DK3059323T3 - DETECTION OF GENETIC PREDICTION FOR OSTEOARTHRITIS-ASSOCIATED CONDITIONS - Google Patents

DETECTION OF GENETIC PREDICTION FOR OSTEOARTHRITIS-ASSOCIATED CONDITIONS Download PDF

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Publication number
DK3059323T3
DK3059323T3 DK15193948.5T DK15193948T DK3059323T3 DK 3059323 T3 DK3059323 T3 DK 3059323T3 DK 15193948 T DK15193948 T DK 15193948T DK 3059323 T3 DK3059323 T3 DK 3059323T3
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Prior art keywords
subject
osteoarthritis
allele
genotype
vol
Prior art date
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DK15193948.5T
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Danish (da)
English (en)
Inventor
Jack F Bukowski
Nazneen Aziz
Hwa-Ying Wang
Kenneth Huttner
Steven B Abramson
Mukundan Attur
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Orig3N Inc
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Publication of DK3059323T3 publication Critical patent/DK3059323T3/en

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    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
    • C12Q1/6883—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00—Oligonucleotides characterized by their use
    • C12Q2600/106—Pharmacogenomics, i.e. genetic variability in individual responses to drugs and drug metabolism
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00—Oligonucleotides characterized by their use
    • C12Q2600/118—Prognosis of disease development
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00—Oligonucleotides characterized by their use
    • C12Q2600/156—Polymorphic or mutational markers
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00—Oligonucleotides characterized by their use
    • C12Q2600/172—Haplotypes

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  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Wood Science & Technology (AREA)
  • Analytical Chemistry (AREA)
  • Zoology (AREA)
  • Genetics & Genomics (AREA)
  • Engineering & Computer Science (AREA)
  • Pathology (AREA)
  • Immunology (AREA)
  • Microbiology (AREA)
  • Molecular Biology (AREA)
  • Biotechnology (AREA)
  • Biophysics (AREA)
  • Physics & Mathematics (AREA)
  • Biochemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
DK15193948.5T 2008-05-02 2009-05-04 DETECTION OF GENETIC PREDICTION FOR OSTEOARTHRITIS-ASSOCIATED CONDITIONS DK3059323T3 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US4999208P 2008-05-02 2008-05-02
US11874408P 2008-12-01 2008-12-01
EP09740020.4A EP2283156B1 (en) 2008-05-02 2009-05-04 Detecting genetic predisposition to osteoarthritis associated conditions

Publications (1)

Publication Number Publication Date
DK3059323T3 true DK3059323T3 (en) 2019-03-04

Family

ID=41210581

Family Applications (2)

Application Number Title Priority Date Filing Date
DK15193948.5T DK3059323T3 (en) 2008-05-02 2009-05-04 DETECTION OF GENETIC PREDICTION FOR OSTEOARTHRITIS-ASSOCIATED CONDITIONS
DK09740020.4T DK2283156T3 (en) 2008-05-02 2009-05-04 Detection of genetic predisposition to conditions associated with osteoarthritis

Family Applications After (1)

Application Number Title Priority Date Filing Date
DK09740020.4T DK2283156T3 (en) 2008-05-02 2009-05-04 Detection of genetic predisposition to conditions associated with osteoarthritis

Country Status (9)

Country Link
US (2) US20100098775A1 (enExample)
EP (3) EP3059323B1 (enExample)
JP (3) JP5762282B2 (enExample)
AU (1) AU2009242490B2 (enExample)
CA (1) CA2723239C (enExample)
DK (2) DK3059323T3 (enExample)
ES (2) ES2708826T3 (enExample)
NZ (1) NZ589034A (enExample)
WO (1) WO2009135218A2 (enExample)

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20100098775A1 (en) * 2008-05-02 2010-04-22 Interleukin Genetics, Inc. Detecting genetic predisposition to osteoarthritis associated conditions
US20120115137A1 (en) * 2010-08-31 2012-05-10 Kornman Kenneth S Methods of Predicting Osteoarthritis
EP2880179B1 (en) * 2012-08-06 2017-12-13 Merck Patent GmbH Genetic markers for predicting responsiveness to fgf-18 compound
PL2880181T3 (pl) * 2012-08-06 2019-03-29 Merck Patent Gmbh Biomarkery prognostyczne w zaburzeniach chrząstki
WO2017123696A1 (en) 2016-01-12 2017-07-20 Interleukin Genetics, Inc. Methods for predicting response to treatment
US10329620B2 (en) 2017-01-12 2019-06-25 Cardioforecast Ltd. Methods and kits for treating cardiovascular disease
RS63292B1 (sr) 2017-09-29 2022-06-30 Merck Patent Gmbh Inflamatorni biomarkeri za predviđanje responsivnosti na jedinjenje fgf-18
LT3687558T (lt) 2017-09-29 2022-06-27 Merck Patent Gmbh Metaboliniai biožymenys, skirti atsako į fgf-18 junginį numatymui
IL281333B2 (en) * 2018-09-10 2025-11-01 Merck Patent Gmbh A method for reducing risk in a clinical trial
US12370240B2 (en) 2018-11-28 2025-07-29 Genascence Corporation Methods and compositions for treating osteoarthritis
EP3980561A1 (en) 2019-06-06 2022-04-13 Sitokine Limited Compositions and methods for treating lung, colorectal and breast cancer
EP4007819A4 (en) * 2019-08-02 2023-08-09 New York University Methods and compositions for treating arthritis
WO2021028469A1 (en) 2019-08-12 2021-02-18 Sitokine Limited Compositions and methods for treating cytokine release syndrome and neurotoxicity
WO2021205013A1 (en) 2020-04-09 2021-10-14 Sitokine Limited Compositions and methods for treating covid-19

Family Cites Families (19)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB8311018D0 (en) 1983-04-22 1983-05-25 Amersham Int Plc Detecting mutations in dna
US4998617A (en) 1986-09-15 1991-03-12 Laura Lupton Inc Facial cosmetic liquid make up kit
US4968607A (en) 1987-11-25 1990-11-06 Immunex Corporation Interleukin-1 receptors
US5459039A (en) 1989-05-12 1995-10-17 Duke University Methods for mapping genetic mutations
FR2650840B1 (fr) 1989-08-11 1991-11-29 Bertin & Cie Procede rapide de detection et/ou d'identification d'une seule base sur une sequence d'acide nucleique, et ses applications
US6004744A (en) 1991-03-05 1999-12-21 Molecular Tool, Inc. Method for determining nucleotide identity through extension of immobilized primer
ATE267877T1 (de) 1993-01-07 2004-06-15 Sequenom Inc Dns - sequenzierung durch massenspektronomie
US5593826A (en) * 1993-03-22 1997-01-14 Perkin-Elmer Corporation, Applied Biosystems, Inc. Enzymatic ligation of 3'amino-substituted oligonucleotides
US5686246A (en) 1995-08-03 1997-11-11 Kornman; Kenneth S. Detecting genetic predisposition to periodontal disease
US5942390A (en) 1996-01-12 1999-08-24 Cedars-Sinai Medical Center Method of diagnosing predisposition for ulcerative colitis in Jewish population by detection of interleukin-1 receptor antagonist polymorphism
US5698399A (en) 1996-04-05 1997-12-16 Duff; Gordon W. Detecting genetic predisposition for osteoporosis
GB9621129D0 (en) * 1996-10-10 1996-11-27 Duff Gordon W Detecting genetic predisposition to sight-threatening diabetic retinopathy
GB9706359D0 (en) * 1997-03-27 1997-05-14 Gemini International Holdings Polymorphisms of an il-1 receptor antagonist gene
GB9711040D0 (en) * 1997-05-29 1997-07-23 Duff Gordon W Prediction of inflammatory disease
JP2005529585A (ja) * 2002-01-25 2005-10-06 インターリューキン ジェネティックス インコーポレイテッド Il−1遺伝子群ならびに関連する炎症性多型およびハプロタイプ
EP1711622A2 (en) * 2003-11-26 2006-10-18 Applera Corporation Genetic polymorphisms associated with cardiovascular disorders and drug response, methods of detection and uses thereof
WO2007070252A2 (en) * 2005-11-30 2007-06-21 The University Of North Carolina At Chapel Hill Identification of genetic polymorphic variants associated with somatosensory disorders and methods of using the same
US20100098775A1 (en) * 2008-05-02 2010-04-22 Interleukin Genetics, Inc. Detecting genetic predisposition to osteoarthritis associated conditions
US9037472B2 (en) 2012-04-20 2015-05-19 Nuance Communications, Inc. Method and system for facilitating communications for a user transaction

Also Published As

Publication number Publication date
ES2561316T3 (es) 2016-02-25
US20100098775A1 (en) 2010-04-22
JP2015211677A (ja) 2015-11-26
CA2723239A1 (en) 2009-11-05
WO2009135218A3 (en) 2010-04-01
CA2723239C (en) 2020-07-21
EP2283156A2 (en) 2011-02-16
JP2018038436A (ja) 2018-03-15
EP3059323B1 (en) 2018-12-12
JP2011520433A (ja) 2011-07-21
JP5762282B2 (ja) 2015-08-12
DK2283156T3 (en) 2016-02-15
NZ589034A (en) 2012-10-26
EP3467126A1 (en) 2019-04-10
JP6263499B2 (ja) 2018-01-17
AU2009242490A1 (en) 2009-11-05
WO2009135218A2 (en) 2009-11-05
AU2009242490B2 (en) 2015-01-22
EP3059323A1 (en) 2016-08-24
US20160340734A1 (en) 2016-11-24
ES2708826T3 (es) 2019-04-11
EP2283156B1 (en) 2015-11-11

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