JP2017528418A5 - - Google Patents
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- JP2017528418A5 JP2017528418A5 JP2016574072A JP2016574072A JP2017528418A5 JP 2017528418 A5 JP2017528418 A5 JP 2017528418A5 JP 2016574072 A JP2016574072 A JP 2016574072A JP 2016574072 A JP2016574072 A JP 2016574072A JP 2017528418 A5 JP2017528418 A5 JP 2017528418A5
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- Prior art keywords
- linker
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Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201462015321P | 2014-06-20 | 2014-06-20 | |
| US62/015,321 | 2014-06-20 | ||
| PCT/US2015/036824 WO2015196167A1 (en) | 2014-06-20 | 2015-06-19 | Anti-folate receptor aplha (fra) antibody-drug conjugates and methods of using thereof |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2017528418A JP2017528418A (ja) | 2017-09-28 |
| JP2017528418A5 true JP2017528418A5 (cg-RX-API-DMAC7.html) | 2018-08-02 |
Family
ID=54936169
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2016574072A Pending JP2017528418A (ja) | 2014-06-20 | 2015-06-19 | 抗葉酸受容体アルファ（ｆｒａ）抗体−薬物コンジュゲート及びその使用方法 |
Country Status (17)
Families Citing this family (20)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| BR112015014712A2 (pt) | 2012-12-21 | 2017-07-11 | Abgenomics Int Inc | ligadores de autoimolação hidrofílicos e seus conjugados |
| AU2015276821A1 (en) | 2014-06-20 | 2017-01-12 | Abgenomics International Inc. | Anti-folate receptor aplha (FRA) antibody-drug conjugates and methods of using thereof |
| KR102793098B1 (ko) * | 2015-06-29 | 2025-04-09 | 이뮤노젠 아이엔씨 | 시스테인 조작된 항체의 콘주게이트 |
| IL260289B (en) | 2016-01-08 | 2022-08-01 | Bioalliance Cv | Tetravalent anti-psgl-1 antibodies and uses thereof |
| CA3044391A1 (en) | 2016-11-23 | 2018-05-31 | Immunogen, Inc. | Selective sulfonation of benzodiazepine derivatives |
| CN107446020B (zh) * | 2017-07-28 | 2019-10-01 | 中国药科大学 | 叶酸受体α特异性结合肽2及其应用 |
| BR112020005212A2 (pt) * | 2017-09-18 | 2020-09-15 | Sutro Biopharma, Inc. | conjugado de anticorpo, kit, composição farmacêutica, e, métodos de tratamento ou prevenção e de diagnóstico de uma doença ou condição. |
| MX2020009522A (es) | 2018-03-13 | 2020-10-22 | Phanes Therapeutics Inc | Anticuerpos anti-folato del receptor 1 y usos de los mismos. |
| WO2020016661A2 (en) * | 2018-07-09 | 2020-01-23 | Multitude Inc. | Antibodies specific to folate receptor alpha |
| CN109053882B (zh) * | 2018-08-28 | 2019-08-23 | 东莞市朋志生物科技有限公司 | 一种ns1蛋白的结合蛋白以及应用 |
| US20220047716A1 (en) * | 2018-09-17 | 2022-02-17 | Sutro Biopharma, Inc. | Combination therapies with anti-folate receptor antibody conjugates |
| CA3140063A1 (en) * | 2019-05-20 | 2020-11-26 | Novartis Ag | Antibody drug conjugates having linkers comprising hydrophilic groups |
| CN111393528B (zh) * | 2020-01-19 | 2023-01-31 | 中国药科大学 | 一种靶向叶酸受体α的单链抗体及其应用 |
| US10981996B1 (en) * | 2020-06-01 | 2021-04-20 | Abexxa Biologics, Inc. | Antibodies targeting a complex comprising non-classical HLA-I and neoantigen and their methods of use |
| US11976120B2 (en) * | 2020-06-01 | 2024-05-07 | Boehringer Ingelheim International Gmbh | Antibodies targeting a complex comprising non-classical HLA-I and neoantigen and their methods of use |
| WO2022198231A1 (en) | 2021-03-18 | 2022-09-22 | Seagen Inc. | Selective drug release from internalized conjugates of biologically active compounds |
| CN112794911B (zh) * | 2021-04-14 | 2021-08-03 | 上海偌妥生物科技有限公司 | 人源化抗叶酸受体1抗体及其应用 |
| TW202504612A (zh) | 2021-11-17 | 2025-02-01 | 美商美國全心醫藥生技股份有限公司 | 使用抗psgl-1抗體組合jak抑制劑來治療t細胞介導發炎性疾病或癌症的方法 |
| AU2024256916A1 (en) | 2023-04-18 | 2025-12-04 | Astrazeneca Ab | Conjugates comprising cleavable linkers |
| WO2025036307A1 (zh) * | 2023-08-11 | 2025-02-20 | 百奥泰生物制药股份有限公司 | 抗frα抗体药物偶联物在治疗疾病中的应用 |
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| US4816567A (en) | 1983-04-08 | 1989-03-28 | Genentech, Inc. | Recombinant immunoglobin preparations |
| GB8823869D0 (en) | 1988-10-12 | 1988-11-16 | Medical Res Council | Production of antibodies |
| US5198560A (en) | 1990-04-27 | 1993-03-30 | Bristol-Myers Squibb Company | Cytotoxic bicyclo[7.3.1]tridec-4-ene-2,6-diyne compounds and process for the preparation thereof |
| US5625126A (en) | 1990-08-29 | 1997-04-29 | Genpharm International, Inc. | Transgenic non-human animals for producing heterologous antibodies |
| US5661016A (en) | 1990-08-29 | 1997-08-26 | Genpharm International Inc. | Transgenic non-human animals capable of producing heterologous antibodies of various isotypes |
| WO1992003918A1 (en) | 1990-08-29 | 1992-03-19 | Genpharm International, Inc. | Transgenic non-human animals capable of producing heterologous antibodies |
| US5633425A (en) | 1990-08-29 | 1997-05-27 | Genpharm International, Inc. | Transgenic non-human animals capable of producing heterologous antibodies |
| US5545806A (en) | 1990-08-29 | 1996-08-13 | Genpharm International, Inc. | Ransgenic non-human animals for producing heterologous antibodies |
| DK0564531T3 (da) | 1990-12-03 | 1998-09-28 | Genentech Inc | Berigelsesfremgangsmåde for variantproteiner med ændrede bindingsegenskaber |
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-
2015
- 2015-06-19 AU AU2015276821A patent/AU2015276821A1/en not_active Abandoned
- 2015-06-19 EP EP15810153.5A patent/EP3157960A4/en not_active Withdrawn
- 2015-06-19 US US14/745,336 patent/US9950077B2/en active Active
- 2015-06-19 SG SG11201610620UA patent/SG11201610620UA/en unknown
- 2015-06-19 CN CN201580044557.8A patent/CN106661124A/zh active Pending
- 2015-06-19 MX MX2016016490A patent/MX2016016490A/es unknown
- 2015-06-19 CA CA2952876A patent/CA2952876A1/en not_active Abandoned
- 2015-06-19 BR BR112016029860A patent/BR112016029860A2/pt not_active Application Discontinuation
- 2015-06-19 WO PCT/US2015/036824 patent/WO2015196167A1/en not_active Ceased
- 2015-06-19 JP JP2016574072A patent/JP2017528418A/ja active Pending
- 2015-06-19 KR KR1020177001294A patent/KR20170020868A/ko not_active Withdrawn
- 2015-06-19 RU RU2017101662A patent/RU2017101662A/ru not_active Application Discontinuation
- 2015-06-22 TW TW104120020A patent/TWI654995B/zh not_active IP Right Cessation
- 2015-06-22 AR ARP150101993A patent/AR100935A1/es unknown
-
2016
- 2016-12-07 IL IL249442A patent/IL249442A0/en unknown
- 2016-12-16 PH PH12016502524A patent/PH12016502524A1/en unknown
- 2016-12-20 ZA ZA2016/08779A patent/ZA201608779B/en unknown
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