JP2017526728A5 - - Google Patents
Download PDFInfo
- Publication number
- JP2017526728A5 JP2017526728A5 JP2017514446A JP2017514446A JP2017526728A5 JP 2017526728 A5 JP2017526728 A5 JP 2017526728A5 JP 2017514446 A JP2017514446 A JP 2017514446A JP 2017514446 A JP2017514446 A JP 2017514446A JP 2017526728 A5 JP2017526728 A5 JP 2017526728A5
- Authority
- JP
- Japan
- Prior art keywords
- montelukast
- medicament
- combination
- disease
- virus
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- 239000003814 drug Substances 0.000 claims 19
- UCHDWCPVSPXUMX-TZIWLTJVSA-N Montelukast Chemical compound CC(C)(O)C1=CC=CC=C1CC[C@H](C=1C=C(\C=C\C=2N=C3C=C(Cl)C=CC3=CC=2)C=CC=1)SCC1(CC(O)=O)CC1 UCHDWCPVSPXUMX-TZIWLTJVSA-N 0.000 claims 13
- 229960005127 montelukast Drugs 0.000 claims 13
- ZKLPARSLTMPFCP-OAQYLSRUSA-N 2-[2-[4-[(R)-(4-chlorophenyl)-phenylmethyl]-1-piperazinyl]ethoxy]acetic acid Chemical compound C1CN(CCOCC(=O)O)CCN1[C@@H](C=1C=CC(Cl)=CC=1)C1=CC=CC=C1 ZKLPARSLTMPFCP-OAQYLSRUSA-N 0.000 claims 9
- 229960001508 levocetirizine Drugs 0.000 claims 9
- 208000036142 Viral infection Diseases 0.000 claims 4
- 230000009385 viral infection Effects 0.000 claims 4
- 208000024827 Alzheimer disease Diseases 0.000 claims 3
- 206010012289 Dementia Diseases 0.000 claims 3
- 241000725619 Dengue virus Species 0.000 claims 3
- 241001115402 Ebolavirus Species 0.000 claims 3
- 201000011240 Frontotemporal dementia Diseases 0.000 claims 3
- 208000023105 Huntington disease Diseases 0.000 claims 3
- 208000009829 Lewy Body Disease Diseases 0.000 claims 3
- 201000002832 Lewy body dementia Diseases 0.000 claims 3
- 208000018737 Parkinson disease Diseases 0.000 claims 3
- 241000710886 West Nile virus Species 0.000 claims 3
- 241000710772 Yellow fever virus Species 0.000 claims 3
- 206010002026 amyotrophic lateral sclerosis Diseases 0.000 claims 3
- 230000001404 mediated effect Effects 0.000 claims 3
- 230000004770 neurodegeneration Effects 0.000 claims 3
- 208000015122 neurodegenerative disease Diseases 0.000 claims 3
- 229940051021 yellow-fever virus Drugs 0.000 claims 3
- 208000004006 Tick-borne encephalitis Diseases 0.000 claims 2
- 101000979342 Homo sapiens Nuclear factor NF-kappa-B p105 subunit Proteins 0.000 claims 1
- 206010061218 Inflammation Diseases 0.000 claims 1
- 208000012902 Nervous system disease Diseases 0.000 claims 1
- 208000025966 Neurological disease Diseases 0.000 claims 1
- 102100023050 Nuclear factor NF-kappa-B p105 subunit Human genes 0.000 claims 1
- 241000580858 Simian-Human immunodeficiency virus Species 0.000 claims 1
- 241000710771 Tick-borne encephalitis virus Species 0.000 claims 1
- 241000700605 Viruses Species 0.000 claims 1
- 239000003795 chemical substances by application Substances 0.000 claims 1
- 229940079593 drug Drugs 0.000 claims 1
- 230000002757 inflammatory effect Effects 0.000 claims 1
- 230000004054 inflammatory process Effects 0.000 claims 1
- 238000007918 intramuscular administration Methods 0.000 claims 1
- 238000007912 intraperitoneal administration Methods 0.000 claims 1
- 238000001990 intravenous administration Methods 0.000 claims 1
- 238000004519 manufacturing process Methods 0.000 claims 1
- 150000003431 steroids Chemical class 0.000 claims 1
- 238000007920 subcutaneous administration Methods 0.000 claims 1
- 238000013268 sustained release Methods 0.000 claims 1
- 239000012730 sustained-release form Substances 0.000 claims 1
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201462050668P | 2014-09-15 | 2014-09-15 | |
| US62/050,668 | 2014-09-15 | ||
| PCT/US2015/049767 WO2016044095A1 (en) | 2014-09-15 | 2015-09-11 | Levocetirizine and montelukast in the treatment of inflammation mediated conditions |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2020070422A Division JP2020109128A (ja) | 2014-09-15 | 2020-04-09 | 炎症介在性状態の治療におけるレボセチリジン及びモンテルカスト |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2017526728A JP2017526728A (ja) | 2017-09-14 |
| JP2017526728A5 true JP2017526728A5 (enExample) | 2018-10-11 |
Family
ID=55533713
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2017514446A Pending JP2017526728A (ja) | 2014-09-15 | 2015-09-11 | 炎症介在性状態の治療におけるレボセチリジン及びモンテルカスト |
| JP2020070422A Pending JP2020109128A (ja) | 2014-09-15 | 2020-04-09 | 炎症介在性状態の治療におけるレボセチリジン及びモンテルカスト |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2020070422A Pending JP2020109128A (ja) | 2014-09-15 | 2020-04-09 | 炎症介在性状態の治療におけるレボセチリジン及びモンテルカスト |
Country Status (4)
| Country | Link |
|---|---|
| US (4) | US9925183B2 (enExample) |
| EP (1) | EP3193875B1 (enExample) |
| JP (2) | JP2017526728A (enExample) |
| WO (1) | WO2016044095A1 (enExample) |
Families Citing this family (12)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP5781606B2 (ja) | 2010-06-16 | 2015-09-24 | インフラマトリー・レスポンス・リサーチ・インコーポレイテッド | インフルエンザ、一般的な感冒および炎症の治療におけるレボセチリジンおよびモンテルカストの使用 |
| AU2014249534B2 (en) | 2013-03-13 | 2018-08-30 | IRR, Inc. | Use of levocetirizine and montelukast in the treatment of vasculitis |
| EP3300734B1 (en) | 2013-03-13 | 2019-08-14 | Inflammatory Response Research, Inc. | Use of levocetirizine and montelukast in the treatment of autoimmune disorders |
| JP6313414B2 (ja) | 2013-03-13 | 2018-04-18 | インフラマトリー・レスポンス・リサーチ・インコーポレイテッド | 外傷性傷害の処置におけるレボセチリジン及びモンテルカストの使用 |
| JP2017526728A (ja) | 2014-09-15 | 2017-09-14 | インフラマトリー・レスポンス・リサーチ・インコーポレイテッド | 炎症介在性状態の治療におけるレボセチリジン及びモンテルカスト |
| CN120053460A (zh) * | 2018-04-27 | 2025-05-30 | 雷莫内克斯生物制药有限公司 | 用于预防或治疗黄病毒感染症的药物组合物 |
| WO2019209035A1 (ko) * | 2018-04-27 | 2019-10-31 | 주식회사 레모넥스 | 플라비바이러스 감염증의 예방 또는 치료용 약학적 조성물 |
| WO2020049505A1 (en) * | 2018-09-06 | 2020-03-12 | Innopharmascreen Inc. | Methods and compositions for treatment of asthma or parkinson's disease |
| SI3678705T1 (sl) * | 2018-09-14 | 2023-10-30 | Enlitisa (Shanghai) Pharmaceutical Co., Ltd. | Konjugati montelukasta in peptidov |
| US12331320B2 (en) | 2018-10-10 | 2025-06-17 | The Research Foundation For The State University Of New York | Genome edited cancer cell vaccines |
| WO2021175831A2 (en) * | 2020-03-02 | 2021-09-10 | Pharma Mar, S.A. | Compounds for use in viral infections |
| WO2021236518A1 (en) * | 2020-05-19 | 2021-11-25 | IRR, Inc. | Levocetirizine and montelukast in the treatment of sepsis and symptoms thereof |
Family Cites Families (65)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4801612A (en) | 1986-07-03 | 1989-01-31 | Regents Of The University Of California | Method of inhibiting inflammatory response |
| US5211958A (en) | 1987-11-30 | 1993-05-18 | Gist-Brocades, N.V. | Pharmaceutical composition and process for its preparation |
| US5147637A (en) | 1988-06-07 | 1992-09-15 | The Rockefeller University | Method of inhibiting the influx of leukocytes into organs during sepsis or other trauma |
| DE69226372T2 (de) | 1991-11-14 | 1999-04-01 | Alliance Pharmaceutical Corp., San Diego, Calif. | Vorrichtung zur teilweisen flüssigen beatmung mit fluorkohlenwasserstoffen |
| JPH09510952A (ja) | 1993-10-06 | 1997-11-04 | ザ ケネディー インスティチュート オブ リューマトロジー | 自己免疫疾患および炎症性疾患の治療 |
| BR9807112A (pt) | 1997-01-24 | 2001-09-18 | Autoimmune Inc | Composição, formulação farmacêutica, combinação e uso relacionados ao tratamento de doenças autoimunes utilizando antìgeno ou agente tolerante em combinação com metotrexato |
| CZ301349B6 (cs) | 1997-12-23 | 2010-01-27 | Schering Corporation | Prostredek k lécbe respiracních a kožních onemocnení, který obsahuje alespon jednoho antagonistu leukotrienu a alespon jedno antihistaminikum |
| AU2470299A (en) | 1998-01-27 | 1999-08-09 | Nutramax Laboratories, Inc. | Combinations of tyrosine, methylating agents, phospholipids, fatty acids, and st. john's wort for the treatment of mental disturbances |
| US6384038B1 (en) | 1998-04-14 | 2002-05-07 | Sepracor Inc. | Methods and compositions using cetirizine in combination with leukotriene inhibitors or decongestants |
| US7186555B1 (en) | 1999-04-13 | 2007-03-06 | The Feinstein Institute For Medical Research | Prevention of brain damage in stroke |
| US20020006961A1 (en) | 1999-05-14 | 2002-01-17 | Katz Stanley E. | Method and composition for treating mammalian nasal and sinus diseases caused by inflammatory response |
| DE10007203A1 (de) | 2000-02-17 | 2001-08-23 | Asta Medica Ag | Neue Kombination nichtsedierender Antihistaminika mit Substanzen, die die Leukotrienwirkung beeinflussen, zur Behandlung der Rhinitis/Konjunktivitis |
| US20010051624A1 (en) | 2000-04-12 | 2001-12-13 | Jones Thomas R. | Method and compositions for the treatment of allergic conditions using PGD2 receptor antagonists |
| US20020052312A1 (en) | 2000-05-30 | 2002-05-02 | Reiss Theodore F. | Combination therapy of chronic obstructive pulmonary disease using muscarinic receptor antagonists |
| DE60119534T2 (de) | 2000-07-28 | 2007-05-10 | Immupharm Aps | Verwendung von hydroxyethylrutosiden zur behandlung von erkältungssymptomen, symptomen der allergischen rhinitis und atemwegsinfektionen |
| US7718198B2 (en) | 2001-06-20 | 2010-05-18 | Metaproteomics, Llc | Treatment modalities for autoimmune diseases |
| PL206069B1 (pl) | 2001-06-28 | 2010-06-30 | Ucb Farchim Sa | Tabletka dwuwarstwowa zawierająca cetyryzynę i pseudoefedrynę |
| ATE401079T1 (de) | 2001-06-29 | 2008-08-15 | Ab Science | Die verwendung von c-kithemmern zur behandlung von autoimmunerkrankungen |
| HU224941B1 (en) | 2001-08-10 | 2006-04-28 | Bgi Innovacios Kft | Phototerapy apparatus |
| AU2003264859A1 (en) | 2001-12-21 | 2003-12-19 | Sampad Bhattacharya | Intranasal pharmaceutical compositions comprising an antihistamine and a leukotriene inhibitor |
| DE50312523D1 (de) | 2002-05-24 | 2010-04-29 | Carl-Fr Coester | Pharmazeutische wirkstoffkombination sowie deren verwendung |
| US7291331B1 (en) | 2002-09-11 | 2007-11-06 | La Jolla Institute For Allergy And Immunology | Methods of treating OX40 medicated recall immune responses |
| CA2518409A1 (en) * | 2003-03-12 | 2004-09-23 | John P. Mullally | Composition and method for treating inflammations by reducing c-reactive protein |
| US7666417B2 (en) | 2003-04-22 | 2010-02-23 | Fred Hutchinson Cancer Research Center | Methods and compositions for treating autoimmune diseases or conditions |
| US20060263350A1 (en) | 2003-09-26 | 2006-11-23 | Fairfield Clinical Trials Llc | Combination antihistamine medication |
| WO2006010283A1 (en) | 2004-07-28 | 2006-02-02 | Universität Zürich | Prevention and treatment of thrombus formation |
| SG165344A1 (en) | 2004-10-05 | 2010-10-28 | Genentech Inc | Method for treating vasculitis |
| US20070244128A1 (en) | 2005-11-04 | 2007-10-18 | Amira Pharmaceuticals, Inc. | 5-lipoxygenase-activating protein (flap) inhibitors |
| US20070225285A1 (en) * | 2005-11-04 | 2007-09-27 | Amira Pharmaceuticals, Inc. | 5-lipoxygenase-activating protein (flap) inhibitors |
| WO2007056510A2 (en) | 2005-11-09 | 2007-05-18 | The Children's Hospital Of Philadelphia | Chloride transport upregulation for the treatment of traumatic brain injury |
| NZ568349A (en) | 2005-12-21 | 2011-05-27 | Meda Pharma Gmbh & Co Kg | Combination of anticholinergics, glucocorticoids, beta2-agonists, PDE 4 inhibitor and antileukotriene for the treatment of inflammatory diseases |
| US7589076B2 (en) | 2006-05-18 | 2009-09-15 | Pgx Health, Llc | Substituted aryl piperidinylalkynyladenosines as A2AR agonists |
| EP2526938A3 (en) | 2007-02-12 | 2013-06-12 | Mike Nicolaou | Histidine decarboxylase inhibitor sole or combined with a leukotriene receptor antagonist, an anti-H1 and/or an anti-H2 to treat COPD or gastrointestinal disorders. |
| EP2129683A4 (en) | 2007-02-26 | 2011-01-05 | Ironwood Pharmaceuticals Inc | METHODS AND COMPOSITIONS FOR TREATMENT OF HEART FAILURE AND OTHER DISORDERS |
| US20110230496A1 (en) | 2007-08-15 | 2011-09-22 | Chemagis Ltd. | Novel process for preparing highly pure levocetirizine and salts thereof |
| US20090227018A1 (en) | 2007-10-25 | 2009-09-10 | Revalesio Corporation | Compositions and methods for modulating cellular membrane-mediated intracellular signal transduction |
| US20100305080A1 (en) | 2007-10-25 | 2010-12-02 | O'shea Paul | Novel Crystalline Salts of Montelukast |
| AU2008316794B2 (en) | 2007-10-25 | 2015-04-23 | Revalesio Corporation | Compositions and methods for modulating cellular membrane-mediated intracellular signal transduction |
| PT2403845E (pt) | 2009-03-02 | 2014-08-04 | Generics Uk Ltd | Processo melhorado |
| WO2010107404A1 (en) | 2009-03-16 | 2010-09-23 | Mahmut Bilgic | Stable pharmaceutical combinations |
| US8263581B2 (en) | 2009-07-03 | 2012-09-11 | Jdp Therapeutics, Inc. | Non-sedating antihistamine injection formulations and methods of use thereof |
| GB2474748B (en) | 2009-10-01 | 2011-10-12 | Amira Pharmaceuticals Inc | Polycyclic compounds as lysophosphatidic acid receptor antagonists |
| BR112012018913A2 (pt) | 2010-01-28 | 2017-06-20 | Merck Sharp & Dohme | "composição farmacêutica, e, uso da composição" |
| JP5781606B2 (ja) | 2010-06-16 | 2015-09-24 | インフラマトリー・レスポンス・リサーチ・インコーポレイテッド | インフルエンザ、一般的な感冒および炎症の治療におけるレボセチリジンおよびモンテルカストの使用 |
| US20120002637A1 (en) | 2010-06-18 | 2012-01-05 | Interdigital Patent Holdings, Inc. | Method and apparatus for supporting home node-b mobility |
| JP2013535456A (ja) | 2010-07-28 | 2013-09-12 | ベーリンガー インゲルハイム インターナショナル ゲゼルシャフト ミット ベシュレンクテル ハフツング | 呼吸器系及び炎症性疾患の治療用医薬組成物 |
| TR201009398A2 (tr) | 2010-11-11 | 2012-05-21 | Bi̇lgi̇ç Mahmut | Fiziksel özellikleri geliştirilmiş tablet formülasyonları |
| US20130030009A1 (en) | 2010-12-30 | 2013-01-31 | Ziv Harish | Method for the treatment and/or prevention of oral allergic symptions of the lips due to oral contact with a food allergen |
| EP2658538A2 (en) | 2010-12-30 | 2013-11-06 | M.D. Ziv Harish | Preparations for topical prevention and/or treatment of oral allergic symptoms due to oral contact with fruits and/or vegetables |
| AU2012242592B2 (en) * | 2011-04-13 | 2016-03-10 | Revalesio Corporation | Compositions and methods for inhibiting and/or modulating effector T-cells involved in inflammatory neurodegenerative disease |
| EP2520292A1 (en) | 2011-05-06 | 2012-11-07 | Helmholtz-Zentrum für Infektionsforschung GmbH | Use of spirangiens for the treatment or prevention of IL-8 or IL-6 mediated disorders |
| KR20130009553A (ko) | 2011-07-15 | 2013-01-23 | 한미약품 주식회사 | 몬테루카스트 또는 이의 약학적으로 허용가능한 염 및 레보세티리진 또는 이의 약학적으로 허용가능한 염을 함유하는 캡슐 제제 |
| WO2013014060A1 (en) | 2011-07-26 | 2013-01-31 | Boehringer Ingelheim International Gmbh | Substituted quinolines and their use as medicaments |
| CN102895661A (zh) | 2011-07-28 | 2013-01-30 | 中国科学院上海药物研究所 | 靶向CysLT1的药物在制备用于预防或治疗自身免疫性疾病的药物中的用途 |
| US9730921B2 (en) * | 2012-03-27 | 2017-08-15 | Duke University | Compositions and methods for the prevention and treatment of mast cell-induced vascular leakage |
| CN103505731A (zh) | 2012-06-15 | 2014-01-15 | 中国药科大学 | 1型半胱氨酰白三烯受体拮抗剂在制备用于治疗阿尔茨海默病的药物中的用途 |
| WO2014090990A1 (en) | 2012-12-13 | 2014-06-19 | Ludwig Aigner | Leukotriene pathway antagonists for the treatment of dementia, cognitive deficits in parkinson's disease and/or learning and memory deficiencies in parkinson's disease |
| WO2014164281A1 (en) | 2013-03-13 | 2014-10-09 | Inflammatory Response Research, Inc. | Use of levocetirizine and montelukast in the treatment of anaphylaxis |
| AU2014249534B2 (en) | 2013-03-13 | 2018-08-30 | IRR, Inc. | Use of levocetirizine and montelukast in the treatment of vasculitis |
| EP3300734B1 (en) | 2013-03-13 | 2019-08-14 | Inflammatory Response Research, Inc. | Use of levocetirizine and montelukast in the treatment of autoimmune disorders |
| JP6313414B2 (ja) | 2013-03-13 | 2018-04-18 | インフラマトリー・レスポンス・リサーチ・インコーポレイテッド | 外傷性傷害の処置におけるレボセチリジン及びモンテルカストの使用 |
| US9371282B2 (en) | 2013-05-17 | 2016-06-21 | Centrexion Therapeutics Corporation | Somatostatin receptor subtype 4 (SSTR4) agonists |
| JP2017526728A (ja) * | 2014-09-15 | 2017-09-14 | インフラマトリー・レスポンス・リサーチ・インコーポレイテッド | 炎症介在性状態の治療におけるレボセチリジン及びモンテルカスト |
| EP3463324A4 (en) | 2016-06-03 | 2020-01-29 | Irr, Inc. | LEVOCETTIRIZINE AND MONTELUKAST IN THE TREATMENT OF MEDIATED CONDITIONS OF MEDIA BY EXPOSURE TO RADIATION |
| WO2021236518A1 (en) | 2020-05-19 | 2021-11-25 | IRR, Inc. | Levocetirizine and montelukast in the treatment of sepsis and symptoms thereof |
-
2015
- 2015-09-11 JP JP2017514446A patent/JP2017526728A/ja active Pending
- 2015-09-11 EP EP15841696.6A patent/EP3193875B1/en active Active
- 2015-09-11 WO PCT/US2015/049767 patent/WO2016044095A1/en not_active Ceased
-
2017
- 2017-03-06 US US15/450,840 patent/US9925183B2/en active Active
-
2018
- 2018-02-13 US US15/895,918 patent/US10195193B2/en active Active
- 2018-12-18 US US16/224,573 patent/US10792281B2/en active Active
-
2020
- 2020-04-09 JP JP2020070422A patent/JP2020109128A/ja active Pending
- 2020-08-31 US US17/007,902 patent/US11590125B2/en active Active
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| JP2017526728A5 (enExample) | ||
| MX381187B (es) | Nuevo derivado de quinoleina para usarse en el tratamiento y prevencion de infecciones virales. | |
| DOP2022000056A (es) | Profármacos antivirales y formulaciones de los mismos | |
| BR112017005917A2 (pt) | processos e composições para indução de imunidade protetora contra infecção com o vírus da imunodeficiência humana | |
| PH12017500797A1 (en) | Substituted chromanes and methods of use | |
| WO2017044507A3 (en) | Sirna/nanoparticle formulations for treatment of middle-east respiratory syndrome coronaviral infection | |
| BR112015003778A2 (pt) | profármaco tenofovir e usos farmacêuticos do mesmo | |
| EA202190602A2 (ru) | 2'-замещенные-n6-замещенные пуриновые нуклеотиды для лечения вызванных рнк-вирусом заболеваний | |
| TR201909152T4 (tr) | Polisiklik-karbamoilpiridon bileşikleri ve bunların farmasötik kullanımı. | |
| JOP20210249A1 (ar) | مشتقات البيرميدون الحلقية المدمجة للاستخدام في علاج عدوىhbv أو الأمراض التي يسببها فيروس hbv | |
| PH12020551709A1 (en) | Antiviral immunotropic agent for the treatment of acute respiratory viral infections | |
| MX2015007563A (es) | Composiciones farmaceuticas. | |
| HRP20211749T1 (hr) | Pentanske kiseline supstituirane pirolo-[2-3,b]pirimidin-piridinima za liječenje virusnih infekcija influencom | |
| MY191515A (en) | Tenofovir monobenzyl ester phosphamide prodrug, preparation method and use thereof | |
| MX2017012272A (es) | Solucion para inhalacion de tiotropio para nebulizacion. | |
| CA2991023C (en) | Attenuated influenza vectors used for the prevention and/or treatment of infectious diseases as well as for the treatment of oncological diseases | |
| PH12019550039A1 (en) | Dihydropyrimidine compound and preparation method and use thereof | |
| DOP2017000086A (es) | Composiciones farmacéuticas de acción prolongada | |
| PH12014502551B1 (en) | Oligonucleotide chelate complex-polypeptide compositions and methods | |
| HRP20210361T1 (hr) | Upotreba pripravka koji sadrži gliceril-tribenzoat kod neurodegenerativnih poremećaja | |
| PH12018502735A1 (en) | Liver delivery-based antiviral precursor drug nucleoside cyclophosphate compound and use thereof | |
| EA202092814A1 (ru) | Пиридоновое производное, его композиция и применение в качестве противовирусного лекарственного средства | |
| DOP2017000114A (es) | Composiciones farmacéuticas de acción prolongada para hepatitis c | |
| DOP2017000116A (es) | Composiciones de acción prolongada de combinación y procedimientos para hepatitis c | |
| MX2019003720A (es) | Composiciones y metodos para tratar el mal de alzheimer y la enfermedad de parkinson. |