MX381187B - Nuevo derivado de quinoleina para usarse en el tratamiento y prevencion de infecciones virales. - Google Patents
Nuevo derivado de quinoleina para usarse en el tratamiento y prevencion de infecciones virales.Info
- Publication number
- MX381187B MX381187B MX2017010506A MX2017010506A MX381187B MX 381187 B MX381187 B MX 381187B MX 2017010506 A MX2017010506 A MX 2017010506A MX 2017010506 A MX2017010506 A MX 2017010506A MX 381187 B MX381187 B MX 381187B
- Authority
- MX
- Mexico
- Prior art keywords
- quinoline derivative
- prevention
- treatment
- viral infections
- present
- Prior art date
Links
- 208000036142 Viral infection Diseases 0.000 title abstract 2
- 230000002265 prevention Effects 0.000 title abstract 2
- SMWDFEZZVXVKRB-UHFFFAOYSA-N Quinoline Chemical class N1=CC=CC2=CC=CC=C21 SMWDFEZZVXVKRB-UHFFFAOYSA-N 0.000 title 1
- 125000002943 quinolinyl group Chemical class N1=C(C=CC2=CC=CC=C12)* 0.000 abstract 3
- 208000030507 AIDS Diseases 0.000 abstract 2
- 241000725303 Human immunodeficiency virus Species 0.000 abstract 2
- 206010038997 Retroviral infections Diseases 0.000 abstract 1
- 150000001875 compounds Chemical class 0.000 abstract 1
- 239000003814 drug Substances 0.000 abstract 1
- 238000004519 manufacturing process Methods 0.000 abstract 1
- 239000008194 pharmaceutical composition Substances 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
- 230000003612 virological effect Effects 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/47—Quinolines; Isoquinolines
- A61K31/4709—Non-condensed quinolines and containing further heterocyclic rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/47—Quinolines; Isoquinolines
- A61K31/472—Non-condensed isoquinolines, e.g. papaverine
- A61K31/4725—Non-condensed isoquinolines, e.g. papaverine containing further heterocyclic rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/14—Antivirals for RNA viruses
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/14—Antivirals for RNA viruses
- A61P31/18—Antivirals for RNA viruses for HIV
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
- C07D405/12—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H17/00—Compounds containing heterocyclic radicals directly attached to hetero atoms of saccharide radicals
- C07H17/02—Heterocyclic radicals containing only nitrogen as ring hetero atoms
Landscapes
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Virology (AREA)
- Molecular Biology (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Engineering & Computer Science (AREA)
- Communicable Diseases (AREA)
- Oncology (AREA)
- Biotechnology (AREA)
- Biochemistry (AREA)
- Genetics & Genomics (AREA)
- Epidemiology (AREA)
- Tropical Medicine & Parasitology (AREA)
- AIDS & HIV (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Saccharide Compounds (AREA)
- Medicinal Preparation (AREA)
Abstract
La presente invención se refiere a un derivado de quinoleína de la fórmula (1) o una de sus sales farmacéuticamente aceptables. La presente invención se refiere además al derivado de quinoleína para el medicamento y para su uso en el tratamiento o prevención de una infección viral o retroviral y en particular el SIDA o una afección relacionada con el SIDA o el virus de inmunodeficiencia humana (VIH). La presente invención se refiere también a una composición farmacéutica que comprende el derivado de quinoleína y al proceso para prepararla como un nuevo compuesto intermedio.
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP15305274.1A EP3059236A1 (en) | 2015-02-23 | 2015-02-23 | A new quinoline derivative for use in the treatment and prevention of viral infections |
| PCT/EP2016/053532 WO2016135052A1 (en) | 2015-02-23 | 2016-02-19 | A new quinoline derivative for use in the treatment and prevention of viral infections |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| MX2017010506A MX2017010506A (es) | 2017-11-13 |
| MX381187B true MX381187B (es) | 2025-03-12 |
Family
ID=52629497
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| MX2017010506A MX381187B (es) | 2015-02-23 | 2016-02-19 | Nuevo derivado de quinoleina para usarse en el tratamiento y prevencion de infecciones virales. |
Country Status (22)
| Country | Link |
|---|---|
| US (1) | US10329317B2 (es) |
| EP (2) | EP3059236A1 (es) |
| JP (1) | JP6797126B2 (es) |
| KR (1) | KR102583506B1 (es) |
| CN (1) | CN107531681B (es) |
| AU (1) | AU2016223687B2 (es) |
| BR (1) | BR112017017500B1 (es) |
| CA (1) | CA2975577C (es) |
| CU (1) | CU24525B1 (es) |
| DK (1) | DK3262037T3 (es) |
| ES (1) | ES2785374T3 (es) |
| HR (1) | HRP20200649T1 (es) |
| HU (1) | HUE048577T2 (es) |
| LT (1) | LT3262037T (es) |
| MX (1) | MX381187B (es) |
| PL (1) | PL3262037T3 (es) |
| PT (1) | PT3262037T (es) |
| RS (1) | RS60369B1 (es) |
| RU (1) | RU2723013C2 (es) |
| SI (1) | SI3262037T1 (es) |
| WO (1) | WO2016135052A1 (es) |
| ZA (1) | ZA201705633B (es) |
Families Citing this family (16)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP2757161A1 (en) | 2013-01-17 | 2014-07-23 | Splicos | miRNA-124 as a biomarker of viral infection |
| EP2974729A1 (en) | 2014-07-17 | 2016-01-20 | Abivax | Quinoline derivatives for use in the treatment of inflammatory diseases |
| EP3059591A1 (en) | 2015-02-23 | 2016-08-24 | Abivax | Methods for screening compounds for treating or preventing a viral infection or a virus-related condition |
| US20190034990A1 (en) * | 2017-07-26 | 2019-01-31 | International Business Machines Corporation | Information insight system for providers of products or services |
| EP3669873A1 (en) * | 2018-12-20 | 2020-06-24 | Abivax | Quinoline derivatives for use ine the traeatment of inflammation diseases |
| EP3669874A1 (en) * | 2018-12-20 | 2020-06-24 | Abivax | Quinoline derivatives for use in the treatment or prevention of cancer |
| EP3881844A1 (en) * | 2020-03-20 | 2021-09-22 | Abivax | Compounds for treating or preventing a coronaviridae infection & methods and uses for assessing the occurrence of a coronaviridae infection |
| BR112022018793A2 (pt) * | 2020-03-20 | 2022-11-29 | Abivax | Uso de um composto de fórmula (i) ou (ii) para tratar ou previnir uma infecção por coronaviridae e condições relacionadas, composição farmacêutica e medicamento compreendendo os mesmos, uso de um mirna como um biomarcador de uma infecção por coronaviridae, e método para avaliar uma infecção por coronaviridae |
| EP3884946A1 (en) * | 2020-03-25 | 2021-09-29 | Abivax | Compounds for treating or preventing a coronaviridae infection & methods and uses for assessing the occurrence of a coronaviridae infection |
| KR20240014059A (ko) * | 2021-05-27 | 2024-01-31 | 지앙수 헨그루이 파마슈티컬스 컴퍼니 리미티드 | 퀴놀린아민 화합물, 이의 제조 방법 및 약제에서의 이의 용도 |
| EP4201948A1 (en) | 2021-12-21 | 2023-06-28 | Abivax | Method of preparation of 1-(n-(quinolin-2-yl)-(phenylamino)-1-deoxy-beta-d-glucopyranuronic acid derivatives |
| EP4212156A1 (en) | 2022-01-13 | 2023-07-19 | Abivax | Combination of 8-chloro-n-(4-(trifluoromethoxy)phenyl)quinolin-2-amine and its derivatives with a s1p receptor modulator |
| EP4215196A1 (en) * | 2022-01-24 | 2023-07-26 | Abivax | Combination of 8-chloro-n-(4-(trifluoromethoxy)phenyl)quinolin-2-amine and its derivatives with a jak inhibitor |
| WO2024109937A1 (zh) * | 2022-11-25 | 2024-05-30 | 江苏恒瑞医药股份有限公司 | 一种喹啉胺类化合物的可药用盐、晶型及其制备方法 |
| WO2024109936A1 (zh) * | 2022-11-25 | 2024-05-30 | 江苏恒瑞医药股份有限公司 | 一种喹啉胺类化合物晶型及其制备方法 |
| CN116617226B (zh) * | 2023-06-21 | 2024-06-25 | 湖北工业大学 | 新型吲哚喹啉衍生物作为肠道病毒71型抑制剂的应用 |
Family Cites Families (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR2436786A1 (fr) | 1978-09-21 | 1980-04-18 | Anvar | Nouveaux derives des pyrido (4,3-b) carbazoles (ellipticines), substitues en position 1 par une chaine polyaminee, leur obtention et leur application a titre de medicaments |
| FR2627493B1 (fr) | 1988-02-23 | 1991-10-31 | Sanofi Sa | Procede de preparation de derives d'isoquinoleine |
| FR2645861A1 (fr) | 1989-04-17 | 1990-10-19 | Inst Nat Sante Rech Med | Utilisation de dipyrido (4,3-b) (3,4-f) indoles pour la preparation de medicaments utiles pour le traitement du sida |
| US5354853A (en) * | 1993-03-12 | 1994-10-11 | Genzyme Corporation | Phospholipid-saccharide conjugates |
| FR2859474B1 (fr) | 2003-09-04 | 2006-01-13 | Centre Nat Rech Scient | Utilisation de composes derives d'indole pour la preparation d'un medicament utile pour le traitement de maladies genetiques resultant de l'alteration des processus d'epissage |
| TR201910781T4 (tr) | 2009-06-12 | 2019-08-21 | Abivax | Kanser tedavisi için yararlı bileşikler. |
| EP2465502A1 (en) | 2010-12-15 | 2012-06-20 | Société Splicos | Compounds useful for treating AIDS |
| US9827237B2 (en) * | 2013-07-05 | 2017-11-28 | Abivax | Compounds useful for treating diseases caused by retroviruses |
| EP2975034A1 (en) | 2014-07-17 | 2016-01-20 | Abivax | A quinoline derivative for the treatment of inflammatory diseases and AIDS |
| EP2974729A1 (en) | 2014-07-17 | 2016-01-20 | Abivax | Quinoline derivatives for use in the treatment of inflammatory diseases |
-
2015
- 2015-02-23 EP EP15305274.1A patent/EP3059236A1/en not_active Withdrawn
-
2016
- 2016-02-19 RS RS20200447A patent/RS60369B1/sr unknown
- 2016-02-19 KR KR1020177023445A patent/KR102583506B1/ko active Active
- 2016-02-19 ES ES16705515T patent/ES2785374T3/es active Active
- 2016-02-19 SI SI201630722T patent/SI3262037T1/sl unknown
- 2016-02-19 BR BR112017017500-2A patent/BR112017017500B1/pt active IP Right Grant
- 2016-02-19 LT LTEP16705515.1T patent/LT3262037T/lt unknown
- 2016-02-19 MX MX2017010506A patent/MX381187B/es unknown
- 2016-02-19 CU CU2017000109A patent/CU24525B1/es unknown
- 2016-02-19 HR HRP20200649TT patent/HRP20200649T1/hr unknown
- 2016-02-19 AU AU2016223687A patent/AU2016223687B2/en active Active
- 2016-02-19 PT PT167055151T patent/PT3262037T/pt unknown
- 2016-02-19 HU HUE16705515A patent/HUE048577T2/hu unknown
- 2016-02-19 CA CA2975577A patent/CA2975577C/en active Active
- 2016-02-19 DK DK16705515.1T patent/DK3262037T3/da active
- 2016-02-19 EP EP16705515.1A patent/EP3262037B1/en active Active
- 2016-02-19 RU RU2017128643A patent/RU2723013C2/ru active
- 2016-02-19 PL PL16705515T patent/PL3262037T3/pl unknown
- 2016-02-19 WO PCT/EP2016/053532 patent/WO2016135052A1/en not_active Ceased
- 2016-02-19 JP JP2017543995A patent/JP6797126B2/ja active Active
- 2016-02-19 US US15/552,587 patent/US10329317B2/en active Active
- 2016-02-19 CN CN201680011519.7A patent/CN107531681B/zh active Active
-
2017
- 2017-08-18 ZA ZA2017/05633A patent/ZA201705633B/en unknown
Also Published As
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| MX381187B (es) | Nuevo derivado de quinoleina para usarse en el tratamiento y prevencion de infecciones virales. | |
| MX2017007814A (es) | Compuesto de carbamoilpiridona policiclicos y su uso farmaceutico. | |
| PH12020551089A1 (en) | Pyrrolopyrimidine compounds used as tlr7 agonist | |
| NZ729150A (en) | Antiretroviral agents | |
| EA201791872A1 (ru) | Полициклические карбамоилпиридоновые соединения и их фармацевтическое применение | |
| PH12015501881A1 (en) | Amide compounds for the treatment of hiv | |
| MD4754B1 (ro) | Compuşi policiclici de carbamoilpiridonă şi utilizarea lor farmaceutică | |
| NZ631726A (en) | Therapeutic compounds for the treatment of viral infections | |
| BR112017022544A2 (pt) | ?composto, composição, e, método para tratamento de infecção por hiv?. | |
| UY35263A (es) | Compuestos terapéuticos | |
| EA201590862A1 (ru) | Фармацевтические композиции | |
| BR112017005917A2 (pt) | processos e composições para indução de imunidade protetora contra infecção com o vírus da imunodeficiência humana | |
| MX384729B (es) | Compuestos heterocíclicos tricíclicos útiles como inhibidores de la integrasa del virus de inmunodeficiencia humana (vih). | |
| BR112018002689A2 (pt) | composto, composição útil e método para tratamento de infecção por hiv | |
| MX2017003928A (es) | Composiciones farmaceuticas de accion prolongada. | |
| DOP2018000035A (es) | Derivados del ácido 5-(n-bencil-tetrahidroisoquinolin-6-il)-piridin-3-il acético como inhibidores de la replicación del virus de la inmunodeficiencia humana | |
| WO2015198263A3 (en) | Novel betulinic proline substituted derivatives as hiv inhibitors | |
| BR112018003181A2 (pt) | composto, composição, e, método para tratar infecção por hiv | |
| BR112018002678A2 (pt) | composto, composição, e, método para tratar infecção por hiv | |
| BR112018002681A2 (pt) | ?composto, composição, e, método para tratamento de infecção por hiv? | |
| EA033921B9 (ru) | Производные сиаловой кислоты и их применение в лечении инфекций, вызываемых вирусом гриппа | |
| BR112018000179A2 (pt) | composto, composição, e, método para tratar a infecção pelo hiv. | |
| WO2015154883A8 (en) | Neosoraphens |