CU24525B1 - Derivado de quinoleína para tratar y prevenir infecciones virales - Google Patents
Derivado de quinoleína para tratar y prevenir infecciones viralesInfo
- Publication number
- CU24525B1 CU24525B1 CU2017000109A CU20170109A CU24525B1 CU 24525 B1 CU24525 B1 CU 24525B1 CU 2017000109 A CU2017000109 A CU 2017000109A CU 20170109 A CU20170109 A CU 20170109A CU 24525 B1 CU24525 B1 CU 24525B1
- Authority
- CU
- Cuba
- Prior art keywords
- derivative
- quinolein
- treat
- viral infections
- prevent viral
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
- C07D405/12—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/47—Quinolines; Isoquinolines
- A61K31/4709—Non-condensed quinolines and containing further heterocyclic rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/47—Quinolines; Isoquinolines
- A61K31/472—Non-condensed isoquinolines, e.g. papaverine
- A61K31/4725—Non-condensed isoquinolines, e.g. papaverine containing further heterocyclic rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/14—Antivirals for RNA viruses
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/14—Antivirals for RNA viruses
- A61P31/18—Antivirals for RNA viruses for HIV
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H17/00—Compounds containing heterocyclic radicals directly attached to hetero atoms of saccharide radicals
- C07H17/02—Heterocyclic radicals containing only nitrogen as ring hetero atoms
Landscapes
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Virology (AREA)
- Molecular Biology (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Engineering & Computer Science (AREA)
- Communicable Diseases (AREA)
- Oncology (AREA)
- Biotechnology (AREA)
- Biochemistry (AREA)
- Genetics & Genomics (AREA)
- Epidemiology (AREA)
- Tropical Medicine & Parasitology (AREA)
- AIDS & HIV (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Saccharide Compounds (AREA)
- Medicinal Preparation (AREA)
Abstract
<p>La presente invención se refiere derivados de quinoleínas de la fórmula (1) y (4)</p> <p>ESPACIO PARA FÓRMULAS</p> <p>o una de sus sales farmacéuticamente aceptables. La presente invención se refiere además al derivado de quinoleína para el medicamento y para su uso en el tratamiento o prevención de una infección viral o retroviral y en particular el SIDA o una afección relacionada con el SIDA o el virus de inmunodeficiencia humana (VIH).</p>
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP15305274.1A EP3059236A1 (en) | 2015-02-23 | 2015-02-23 | A new quinoline derivative for use in the treatment and prevention of viral infections |
| PCT/EP2016/053532 WO2016135052A1 (en) | 2015-02-23 | 2016-02-19 | A new quinoline derivative for use in the treatment and prevention of viral infections |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CU20170109A7 CU20170109A7 (es) | 2018-02-08 |
| CU24525B1 true CU24525B1 (es) | 2021-06-08 |
Family
ID=52629497
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CU2017000109A CU24525B1 (es) | 2015-02-23 | 2016-02-19 | Derivado de quinoleína para tratar y prevenir infecciones virales |
Country Status (22)
| Country | Link |
|---|---|
| US (1) | US10329317B2 (es) |
| EP (2) | EP3059236A1 (es) |
| JP (1) | JP6797126B2 (es) |
| KR (1) | KR102583506B1 (es) |
| CN (1) | CN107531681B (es) |
| AU (1) | AU2016223687B2 (es) |
| BR (1) | BR112017017500B1 (es) |
| CA (1) | CA2975577C (es) |
| CU (1) | CU24525B1 (es) |
| DK (1) | DK3262037T3 (es) |
| ES (1) | ES2785374T3 (es) |
| HR (1) | HRP20200649T1 (es) |
| HU (1) | HUE048577T2 (es) |
| LT (1) | LT3262037T (es) |
| MX (1) | MX2017010506A (es) |
| PL (1) | PL3262037T3 (es) |
| PT (1) | PT3262037T (es) |
| RS (1) | RS60369B1 (es) |
| RU (1) | RU2723013C2 (es) |
| SI (1) | SI3262037T1 (es) |
| WO (1) | WO2016135052A1 (es) |
| ZA (1) | ZA201705633B (es) |
Families Citing this family (13)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP2757161A1 (en) | 2013-01-17 | 2014-07-23 | Splicos | miRNA-124 as a biomarker of viral infection |
| EP2974729A1 (en) | 2014-07-17 | 2016-01-20 | Abivax | Quinoline derivatives for use in the treatment of inflammatory diseases |
| EP3059591A1 (en) | 2015-02-23 | 2016-08-24 | Abivax | Methods for screening compounds for treating or preventing a viral infection or a virus-related condition |
| US20190034990A1 (en) * | 2017-07-26 | 2019-01-31 | International Business Machines Corporation | Information insight system for providers of products or services |
| EP3669874A1 (en) * | 2018-12-20 | 2020-06-24 | Abivax | Quinoline derivatives for use in the treatment or prevention of cancer |
| WO2021186053A1 (en) * | 2020-03-20 | 2021-09-23 | Abivax | Compounds for treating or preventing a coronaviridae infection & methods and uses for assessing the occurrence of a coronaviridae infection |
| EP3881844A1 (en) * | 2020-03-20 | 2021-09-22 | Abivax | Compounds for treating or preventing a coronaviridae infection & methods and uses for assessing the occurrence of a coronaviridae infection |
| EP3884946A1 (en) * | 2020-03-25 | 2021-09-29 | Abivax | Compounds for treating or preventing a coronaviridae infection & methods and uses for assessing the occurrence of a coronaviridae infection |
| WO2022247920A1 (zh) * | 2021-05-27 | 2022-12-01 | 江苏恒瑞医药股份有限公司 | 喹啉胺类化合物、其制备方法及其在医药上的应用 |
| EP4201948A1 (en) | 2021-12-21 | 2023-06-28 | Abivax | Method of preparation of 1-(n-(quinolin-2-yl)-(phenylamino)-1-deoxy-beta-d-glucopyranuronic acid derivatives |
| EP4212156A1 (en) | 2022-01-13 | 2023-07-19 | Abivax | Combination of 8-chloro-n-(4-(trifluoromethoxy)phenyl)quinolin-2-amine and its derivatives with a s1p receptor modulator |
| EP4215196A1 (en) * | 2022-01-24 | 2023-07-26 | Abivax | Combination of 8-chloro-n-(4-(trifluoromethoxy)phenyl)quinolin-2-amine and its derivatives with a jak inhibitor |
| CN116617226A (zh) * | 2023-06-21 | 2023-08-22 | 湖北工业大学 | 新型吲哚喹啉衍生物作为肠道病毒71型抑制剂的应用 |
Family Cites Families (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR2436786A1 (fr) | 1978-09-21 | 1980-04-18 | Anvar | Nouveaux derives des pyrido (4,3-b) carbazoles (ellipticines), substitues en position 1 par une chaine polyaminee, leur obtention et leur application a titre de medicaments |
| FR2627493B1 (fr) | 1988-02-23 | 1991-10-31 | Sanofi Sa | Procede de preparation de derives d'isoquinoleine |
| FR2645861A1 (fr) | 1989-04-17 | 1990-10-19 | Inst Nat Sante Rech Med | Utilisation de dipyrido (4,3-b) (3,4-f) indoles pour la preparation de medicaments utiles pour le traitement du sida |
| US5354853A (en) * | 1993-03-12 | 1994-10-11 | Genzyme Corporation | Phospholipid-saccharide conjugates |
| FR2859474B1 (fr) | 2003-09-04 | 2006-01-13 | Centre Nat Rech Scient | Utilisation de composes derives d'indole pour la preparation d'un medicament utile pour le traitement de maladies genetiques resultant de l'alteration des processus d'epissage |
| CN106928194B (zh) * | 2009-06-12 | 2019-11-12 | Abivax公司 | 用于治疗过早衰老和尤其是早衰的化合物 |
| EP2465502A1 (en) | 2010-12-15 | 2012-06-20 | Société Splicos | Compounds useful for treating AIDS |
| RU2681943C9 (ru) * | 2013-07-05 | 2019-05-16 | Абивакс | Соединения, полезные для лечения заболеваний, вызванных ретровирусами |
| EP2974729A1 (en) | 2014-07-17 | 2016-01-20 | Abivax | Quinoline derivatives for use in the treatment of inflammatory diseases |
| EP2975034A1 (en) | 2014-07-17 | 2016-01-20 | Abivax | A quinoline derivative for the treatment of inflammatory diseases and AIDS |
-
2015
- 2015-02-23 EP EP15305274.1A patent/EP3059236A1/en not_active Withdrawn
-
2016
- 2016-02-19 KR KR1020177023445A patent/KR102583506B1/ko active IP Right Grant
- 2016-02-19 EP EP16705515.1A patent/EP3262037B1/en active Active
- 2016-02-19 BR BR112017017500-2A patent/BR112017017500B1/pt active IP Right Grant
- 2016-02-19 HU HUE16705515A patent/HUE048577T2/hu unknown
- 2016-02-19 AU AU2016223687A patent/AU2016223687B2/en active Active
- 2016-02-19 US US15/552,587 patent/US10329317B2/en active Active
- 2016-02-19 CA CA2975577A patent/CA2975577C/en active Active
- 2016-02-19 CU CU2017000109A patent/CU24525B1/es unknown
- 2016-02-19 MX MX2017010506A patent/MX2017010506A/es unknown
- 2016-02-19 SI SI201630722T patent/SI3262037T1/sl unknown
- 2016-02-19 ES ES16705515T patent/ES2785374T3/es active Active
- 2016-02-19 JP JP2017543995A patent/JP6797126B2/ja active Active
- 2016-02-19 DK DK16705515.1T patent/DK3262037T3/da active
- 2016-02-19 PT PT167055151T patent/PT3262037T/pt unknown
- 2016-02-19 RU RU2017128643A patent/RU2723013C2/ru active
- 2016-02-19 LT LTEP16705515.1T patent/LT3262037T/lt unknown
- 2016-02-19 CN CN201680011519.7A patent/CN107531681B/zh active Active
- 2016-02-19 WO PCT/EP2016/053532 patent/WO2016135052A1/en active Application Filing
- 2016-02-19 PL PL16705515T patent/PL3262037T3/pl unknown
- 2016-02-19 RS RS20200447A patent/RS60369B1/sr unknown
-
2017
- 2017-08-18 ZA ZA2017/05633A patent/ZA201705633B/en unknown
-
2020
- 2020-04-22 HR HRP20200649TT patent/HRP20200649T1/hr unknown
Also Published As
| Publication number | Publication date |
|---|---|
| ES2785374T3 (es) | 2020-10-06 |
| KR20170129698A (ko) | 2017-11-27 |
| BR112017017500B1 (pt) | 2023-04-04 |
| EP3262037A1 (en) | 2018-01-03 |
| JP6797126B2 (ja) | 2020-12-09 |
| JP2018507215A (ja) | 2018-03-15 |
| WO2016135052A1 (en) | 2016-09-01 |
| RS60369B1 (sr) | 2020-07-31 |
| US20180030078A1 (en) | 2018-02-01 |
| CA2975577C (en) | 2020-04-07 |
| SI3262037T1 (sl) | 2020-09-30 |
| RU2017128643A3 (es) | 2019-04-15 |
| BR112017017500A2 (pt) | 2018-04-17 |
| RU2723013C2 (ru) | 2020-06-08 |
| US10329317B2 (en) | 2019-06-25 |
| PT3262037T (pt) | 2020-04-09 |
| CA2975577A1 (en) | 2016-09-01 |
| EP3262037B1 (en) | 2020-02-12 |
| RU2017128643A (ru) | 2019-03-25 |
| PL3262037T3 (pl) | 2020-10-19 |
| HUE048577T2 (hu) | 2020-07-28 |
| AU2016223687B2 (en) | 2020-03-19 |
| LT3262037T (lt) | 2020-07-10 |
| DK3262037T3 (da) | 2020-05-04 |
| CN107531681B (zh) | 2020-11-24 |
| ZA201705633B (en) | 2018-12-19 |
| AU2016223687A1 (en) | 2017-08-31 |
| MX2017010506A (es) | 2017-11-13 |
| CN107531681A (zh) | 2018-01-02 |
| EP3059236A1 (en) | 2016-08-24 |
| HRP20200649T1 (hr) | 2020-10-16 |
| CU20170109A7 (es) | 2018-02-08 |
| KR102583506B1 (ko) | 2023-09-26 |
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