JP2017526339A5 - - Google Patents
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- Publication number
- JP2017526339A5 JP2017526339A5 JP2016573964A JP2016573964A JP2017526339A5 JP 2017526339 A5 JP2017526339 A5 JP 2017526339A5 JP 2016573964 A JP2016573964 A JP 2016573964A JP 2016573964 A JP2016573964 A JP 2016573964A JP 2017526339 A5 JP2017526339 A5 JP 2017526339A5
- Authority
- JP
- Japan
- Prior art keywords
- antibody
- domain
- axl
- seq
- nucleic acid
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB1410825.2 | 2014-06-18 | ||
| GBGB1410825.2A GB201410825D0 (en) | 2014-06-18 | 2014-06-18 | Anti-axl antibodies |
| PCT/EP2015/063704 WO2015193430A1 (en) | 2014-06-18 | 2015-06-18 | Anti-axl antibodies |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2017526339A JP2017526339A (ja) | 2017-09-14 |
| JP2017526339A5 true JP2017526339A5 (enExample) | 2018-05-10 |
| JP6787796B2 JP6787796B2 (ja) | 2020-11-18 |
Family
ID=51266760
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2016573964A Expired - Fee Related JP6787796B2 (ja) | 2014-06-18 | 2015-06-18 | 抗Ａｘｌ抗体 |
Country Status (10)
| Country | Link |
|---|---|
| US (1) | US9975953B2 (enExample) |
| EP (1) | EP3157575B1 (enExample) |
| JP (1) | JP6787796B2 (enExample) |
| KR (1) | KR102408356B1 (enExample) |
| CN (2) | CN113321732B (enExample) |
| AU (1) | AU2015276155B2 (enExample) |
| CA (1) | CA2952113A1 (enExample) |
| GB (1) | GB201410825D0 (enExample) |
| MX (1) | MX375524B (enExample) |
| WO (1) | WO2015193430A1 (enExample) |
Families Citing this family (22)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB201410826D0 (en) | 2014-06-18 | 2014-07-30 | Bergenbio As | Anti-axl antibodies |
| DK3169706T3 (da) | 2014-07-11 | 2020-03-09 | Genmab As | Antistoffer, der binder axl |
| EP3229836B1 (en) * | 2014-12-09 | 2019-11-13 | Institut National de la Sante et de la Recherche Medicale (INSERM) | Human monoclonal antibodies against axl |
| WO2016097370A2 (en) | 2014-12-18 | 2016-06-23 | Bergen Teknologioverføring As | Anti-axl antagonistic antibodies |
| GB201506411D0 (en) | 2015-04-15 | 2015-05-27 | Bergenbio As | Humanized anti-axl antibodies |
| GB201509338D0 (en) | 2015-05-29 | 2015-07-15 | Bergenbio As | Combination therapy |
| CA2991805A1 (en) * | 2015-07-10 | 2017-01-19 | Genmab A/S | Axl-specific antibody-drug conjugates for cancer treatment |
| EP4656204A3 (en) * | 2016-04-15 | 2026-06-03 | BioAtla, Inc. | Anti-axl antibodies, antibody fragments and their immunoconjugates and uses thereof |
| GB201610902D0 (en) | 2016-06-22 | 2016-08-03 | Bergen Teknologioverforing As And Bergenbio As | Anti-Axl Antagonistic Antibodies |
| CN107973854B (zh) * | 2017-12-11 | 2021-05-04 | 苏州银河生物医药有限公司 | Pdl1单克隆抗体及其应用 |
| EP3774904A1 (en) * | 2018-04-10 | 2021-02-17 | Genmab A/S | Axl-specific antibodies for cancer treatment |
| US20210215697A1 (en) | 2018-05-14 | 2021-07-15 | Bergenbio Asa | Serum Biomarkers |
| CN110540592B (zh) * | 2018-05-29 | 2022-08-09 | 杭州尚健生物技术有限公司 | 结合axl蛋白的抗体及其应用 |
| CN112955240B (zh) * | 2018-10-25 | 2022-09-16 | 豪夫迈·罗氏有限公司 | 抗体FcRn结合的修饰 |
| GB201912059D0 (en) | 2019-08-22 | 2019-10-09 | Bergenbio As | Combaination therapy of a patient subgroup |
| CN115052663B (zh) | 2020-01-08 | 2026-06-09 | 辛瑟斯治疗股份有限公司 | Alk5抑制剂缀合物及其用途 |
| GB202004189D0 (en) | 2020-03-23 | 2020-05-06 | Bergenbio As | Combination therapy |
| WO2021204713A1 (en) | 2020-04-08 | 2021-10-14 | Bergenbio Asa | Axl inhibitors for antiviral therapy |
| GB202006072D0 (en) | 2020-04-24 | 2020-06-10 | Bergenbio Asa | Method of selecting patients for treatment with cmbination therapy |
| WO2022164288A1 (ko) | 2021-01-29 | 2022-08-04 | 한국과학기술원 | 비염증성 식세포작용 유도 활성을 갖는 융합분자 |
| GB202104037D0 (en) | 2021-03-23 | 2021-05-05 | Bergenbio Asa | Combination therapy |
| CN113444180B (zh) * | 2021-06-16 | 2023-03-31 | 上海鑫湾生物科技有限公司 | 靶向axl蛋白的抗体及其抗原结合片段、其制备方法和应用 |
Family Cites Families (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| BRPI0820073A2 (pt) | 2007-11-12 | 2015-06-23 | U3 Pharma Gmbh | Anticorpos anti-axl |
| CN101918452A (zh) | 2007-11-15 | 2010-12-15 | 中外制药株式会社 | 与Anexelekto结合的单克隆抗体及其利用 |
| CN102459344A (zh) | 2009-05-15 | 2012-05-16 | 中外制药株式会社 | 抗axl抗体 |
| TW201106972A (en) * | 2009-07-27 | 2011-03-01 | Genentech Inc | Combination treatments |
| CN103080136B (zh) * | 2010-06-18 | 2015-08-12 | 霍夫曼-拉罗奇有限公司 | 抗Axl抗体及使用方法 |
| AU2012273955A1 (en) | 2011-06-22 | 2014-01-09 | Inserm (Institut National De La Sante Et De La Recherche Medicale) | Anti-Axl antibodies and uses thereof |
| WO2012175691A1 (en) * | 2011-06-22 | 2012-12-27 | INSERM (Institut National de la Santé et de la Recherche Médicale) | Anti-axl antibodies and uses thereof |
| EP2589609A1 (en) | 2011-11-03 | 2013-05-08 | Pierre Fabre Medicament | Antigen binding protein and its use as addressing product for the treatment of cancer |
| CN108341873B (zh) * | 2011-12-05 | 2022-03-25 | 诺华股份有限公司 | 表皮生长因子受体3(her3)的抗体 |
| GB201410826D0 (en) | 2014-06-18 | 2014-07-30 | Bergenbio As | Anti-axl antibodies |
| WO2016097370A2 (en) * | 2014-12-18 | 2016-06-23 | Bergen Teknologioverføring As | Anti-axl antagonistic antibodies |
-
2014
- 2014-06-18 GB GBGB1410825.2A patent/GB201410825D0/en not_active Ceased
-
2015
- 2015-06-18 US US15/318,023 patent/US9975953B2/en not_active Expired - Fee Related
- 2015-06-18 CA CA2952113A patent/CA2952113A1/en active Pending
- 2015-06-18 CN CN202110419463.1A patent/CN113321732B/zh not_active Expired - Fee Related
- 2015-06-18 MX MX2016016886A patent/MX375524B/es active IP Right Grant
- 2015-06-18 KR KR1020177001481A patent/KR102408356B1/ko not_active Expired - Fee Related
- 2015-06-18 AU AU2015276155A patent/AU2015276155B2/en not_active Ceased
- 2015-06-18 WO PCT/EP2015/063704 patent/WO2015193430A1/en not_active Ceased
- 2015-06-18 CN CN201580042718.XA patent/CN106573980B/zh not_active Expired - Fee Related
- 2015-06-18 JP JP2016573964A patent/JP6787796B2/ja not_active Expired - Fee Related
- 2015-06-18 EP EP15729850.6A patent/EP3157575B1/en active Active
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