JP2017523959A5 - - Google Patents

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Publication number
JP2017523959A5
JP2017523959A5 JP2016575360A JP2016575360A JP2017523959A5 JP 2017523959 A5 JP2017523959 A5 JP 2017523959A5 JP 2016575360 A JP2016575360 A JP 2016575360A JP 2016575360 A JP2016575360 A JP 2016575360A JP 2017523959 A5 JP2017523959 A5 JP 2017523959A5
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JP
Japan
Prior art keywords
pharmaceutically acceptable
composition
acceptable salt
hepcidin
hepcidin analog
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
JP2016575360A
Other languages
English (en)
Japanese (ja)
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JP2017523959A (ja
Filing date
Publication date
Application filed filed Critical
Priority claimed from PCT/US2015/038370 external-priority patent/WO2015200916A2/en
Publication of JP2017523959A publication Critical patent/JP2017523959A/ja
Publication of JP2017523959A5 publication Critical patent/JP2017523959A5/ja
Withdrawn legal-status Critical Current

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JP2016575360A 2014-06-27 2015-06-29 ヘプシジンおよびミニ−ヘプシジンアナログおよびその使用 Withdrawn JP2017523959A (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201462018382P 2014-06-27 2014-06-27
US62/018,382 2014-06-27
PCT/US2015/038370 WO2015200916A2 (en) 2014-06-27 2015-06-29 Hepcidin and mini-hepcidin analogues and uses therof

Publications (2)

Publication Number Publication Date
JP2017523959A JP2017523959A (ja) 2017-08-24
JP2017523959A5 true JP2017523959A5 (enExample) 2019-02-28

Family

ID=54938965

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2016575360A Withdrawn JP2017523959A (ja) 2014-06-27 2015-06-29 ヘプシジンおよびミニ−ヘプシジンアナログおよびその使用

Country Status (10)

Country Link
US (2) US20170313754A1 (enExample)
EP (1) EP3161164A4 (enExample)
JP (1) JP2017523959A (enExample)
KR (1) KR20170043509A (enExample)
CN (1) CN107075574A (enExample)
AU (1) AU2015279571A1 (enExample)
CA (1) CA2953721A1 (enExample)
IL (1) IL249692A0 (enExample)
SG (1) SG11201610799WA (enExample)
WO (1) WO2015200916A2 (enExample)

Families Citing this family (42)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2448382C (en) 2001-05-25 2013-02-19 Institut National De La Sante Et De La Recherche Medicale (Inserm) Use of hepcidin as a regulator of iron homeostasis
KR102236829B1 (ko) * 2013-03-15 2021-04-07 프로타고니스트 테라퓨틱스, 인코포레이티드 헵시딘 유사체 및 이의 용도
US11504346B2 (en) 2013-11-03 2022-11-22 Arizona Board Of Regents On Behalf Of The University Of Arizona Redox-activated pro-chelators
US12383518B2 (en) 2013-11-03 2025-08-12 Arizona Board Of Regents On Behalf Of The University Of Arizona Disulfide-masked pro-chelator compositions and methods of use
AU2015258863B2 (en) 2014-05-16 2019-10-24 Protagonist Therapeutics, Inc. Alpha4beta7 integrin thioether peptide antagonists
AU2015289642B2 (en) 2014-07-17 2021-02-25 Protagonist Therapeutics, Inc. Oral peptide inhibitors of interleukin-23 receptor and their use to treat inflammatory bowel diseases
WO2016054411A1 (en) 2014-10-01 2016-04-07 Protagonist Therapeutics, Inc. NOVEL α4β7 PEPTIDE MONOMER AND DIMER ANTAGONISTS
EP3201217A4 (en) 2014-10-01 2018-07-18 Protagonist Therapeutics Inc. Novel cyclic monomer and dimer peptides having integrin antagonist activity
US10787490B2 (en) 2015-07-15 2020-09-29 Protaganist Therapeutics, Inc. Peptide inhibitors of interleukin-23 receptor and their use to treat inflammatory diseases
WO2017117411A1 (en) * 2015-12-30 2017-07-06 Protagonist Therapeutics, Inc. Analogues of hepcidin mimetics with improved in vivo half lives
KR20180109917A (ko) * 2016-01-08 2018-10-08 라 졸라 파마슈티칼 컴파니 헵시딘의 투여 방법
EP3432906A4 (en) 2016-03-23 2020-04-01 Protagonist Therapeutics, Inc. METHOD FOR SYNTHETIZING ALPHA4BETA7 PEPTIDE ANTAGONISTS
AU2017324446A1 (en) * 2016-09-06 2019-03-28 La Jolla Pharmceutical Company Methods of treating iron overload
AU2017378976A1 (en) * 2016-12-19 2019-07-04 La Jolla Pharmaceutical Company Methods of administering hepcidin
WO2018128828A1 (en) 2016-12-23 2018-07-12 Bayer Healthcare Llc Novel hepcidin mimetics and uses thereof
US20200170971A1 (en) * 2017-07-18 2020-06-04 Arizona Board Of Regents On Behalf Of The University Of Arizona Disulfide-masked pro-chelator compositions and methods of use
US10278957B2 (en) 2017-09-11 2019-05-07 Protagonist Therapeutics, Inc. Opioid agonist peptides and uses thereof
EP3749345A4 (en) 2018-02-08 2022-04-06 Protagonist Therapeutics, Inc. CONJUGATED HEPCIDIN MIMETICS
TW202019948A (zh) 2018-07-12 2020-06-01 美商領導醫療有限公司 介白素-23受體之肽抑制劑及其治療發炎疾病之用途
US11286243B2 (en) 2018-12-13 2022-03-29 Global Blood Therapeutics, Inc. Ferroportin inhibitors and methods of use
CN114585637B (zh) 2019-05-07 2025-04-15 拜耳公司 Masp抑制化合物及其用途
MX2022000397A (es) 2019-07-10 2022-04-25 Protagonist Therapeutics Inc Inhibidores peptídicos del receptor de interleucina-23 y su uso para tratar enfermedades inflamatorias.
EP4025592B1 (en) * 2019-09-03 2025-10-29 Protagonist Therapeutics, Inc. Conjugated hepcidin mimetics for use in treating of polycythemia vera
WO2021062171A1 (en) * 2019-09-27 2021-04-01 Disc Medicine, Inc. Methods for treating anemia of chronic disease
JP2022549506A (ja) * 2019-09-27 2022-11-25 ディスク・メディシン・インコーポレイテッド 骨髄線維症および関連状態を処置するための方法
KR20220141808A (ko) 2020-01-15 2022-10-20 얀센 바이오테크 인코포레이티드 인터루킨-23 수용체의 펩티드 억제제 및 염증성 질환을 치료하기 위한 이의 용도
CN118063554A (zh) 2020-01-15 2024-05-24 詹森生物科技公司 介白素-23受体的肽抑制剂及其治疗炎性疾病的用途
CA3181577A1 (en) 2020-04-28 2021-11-04 Global Blood Therapeutics, Inc. Thieno pyrimidines as ferroportin inhibitors
PE20230845A1 (es) 2020-04-28 2023-05-23 Global Blood Therapeutics Inc Pirimidinas cicloalquiladas como inhibidores de la ferroportina
US20230226074A1 (en) 2020-04-28 2023-07-20 Global Blood Therapeutics, Inc. Methods of use for pyrimidines as ferroportin inhibitors
KR20230012539A (ko) 2020-05-13 2023-01-26 디스크 메디슨, 인크. 골수섬유증을 치료하기 위한 항-헤모주벨린 (hjv) 항체
CN111560051B (zh) * 2020-05-26 2022-11-25 大连工业大学 一种具有促铁吸收活性的虾源九肽及其应用
US20230324413A1 (en) * 2020-07-02 2023-10-12 Tampere University Foundation Sr Renin-based analysis of hepcidin
KR20230053615A (ko) * 2020-07-28 2023-04-21 프로타고니스트 테라퓨틱스, 인코포레이티드 접합된 헵시딘 모방체
CN114252627A (zh) * 2020-09-24 2022-03-29 首都医科大学附属北京世纪坛医院 尿液铁调素及其多肽片段在过敏性疾病中的应用
KR20230110570A (ko) 2020-11-20 2023-07-24 얀센 파마슈티카 엔.브이. 인터류킨-23 수용체의 펩티드 억제제의 조성물
WO2022212696A1 (en) * 2021-04-01 2022-10-06 Protagonist Therapeutics, Inc. Conjugated hepcidin mimetics
WO2022266060A1 (en) 2021-06-14 2022-12-22 Protagonist Therapeutics, Inc. Hepcidin mimetics for treatment of hereditary hemochromatosis
TW202330013A (zh) 2021-07-14 2023-08-01 美商健生生物科技公司 介白素-23受體之脂化肽抑制劑
CN115703826B (zh) * 2021-08-03 2025-05-06 浙江大学 铁调素改造体及其应用
EP4587034A1 (en) * 2022-09-15 2025-07-23 Migal Galilee Research Institute Ltd Site-specific activation of regulatory t cells
WO2025224128A1 (en) 2024-04-24 2025-10-30 Institut National de la Santé et de la Recherche Médicale Methods of treatment of iron overload associated diseases by administration hepcidin locally in the gut

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AR065083A1 (es) * 2007-02-02 2009-05-13 Amgen Inc Hepcidina, antagonistas de la hepcidina y metodos de uso
CN101358201A (zh) * 2007-07-31 2009-02-04 钱忠明 重组人铁调素腺病毒、其制备方法及应用
CN101307085B (zh) * 2007-08-01 2012-06-13 香港理工大学深圳研究院 抑制铁调素调节蛋白的siRNA、重组慢病毒及其应用
GR1006896B (el) * 2007-08-24 2010-07-20 Ελληνικο Ινστιτουτο Παστερ, Μεθοδος παραγωγης μιας πεπτιδικης ορμονης
WO2010065815A2 (en) * 2008-12-05 2010-06-10 The Regents Of The University Of California Mini-hepcidin peptides and methods of using thereof
US20130236977A1 (en) * 2010-05-24 2013-09-12 Children's Medical Center Corporation Compositions and methods for plasma peptide analysis
BR112014013697A2 (pt) * 2011-12-09 2020-11-03 The Regents Of The University Of California peptídeos mini-hepcidina modificados e métodos de uso dos mesmos
KR102236829B1 (ko) * 2013-03-15 2021-04-07 프로타고니스트 테라퓨틱스, 인코포레이티드 헵시딘 유사체 및 이의 용도

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