SG11201610799WA - Hepcidin and mini-hepcidin analogues and uses therof - Google Patents
Hepcidin and mini-hepcidin analogues and uses therofInfo
- Publication number
- SG11201610799WA SG11201610799WA SG11201610799WA SG11201610799WA SG11201610799WA SG 11201610799W A SG11201610799W A SG 11201610799WA SG 11201610799W A SG11201610799W A SG 11201610799WA SG 11201610799W A SG11201610799W A SG 11201610799WA SG 11201610799W A SG11201610799W A SG 11201610799WA
- Authority
- SG
- Singapore
- Prior art keywords
- hepcidin
- mini
- analogues
- uses therof
- therof
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/575—Hormones
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/06—Antianaemics
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
- C07K7/04—Linear peptides containing only normal peptide links
- C07K7/06—Linear peptides containing only normal peptide links having 5 to 11 amino acids
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
- C07K7/04—Linear peptides containing only normal peptide links
- C07K7/08—Linear peptides containing only normal peptide links having 12 to 20 amino acids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Molecular Biology (AREA)
- Genetics & Genomics (AREA)
- Biophysics (AREA)
- Biochemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pharmacology & Pharmacy (AREA)
- Engineering & Computer Science (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Gastroenterology & Hepatology (AREA)
- Toxicology (AREA)
- Zoology (AREA)
- Endocrinology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Diabetes (AREA)
- Hematology (AREA)
- Immunology (AREA)
- Epidemiology (AREA)
- Obesity (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Peptides Or Proteins (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201462018382P | 2014-06-27 | 2014-06-27 | |
| PCT/US2015/038370 WO2015200916A2 (en) | 2014-06-27 | 2015-06-29 | Hepcidin and mini-hepcidin analogues and uses therof |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| SG11201610799WA true SG11201610799WA (en) | 2017-01-27 |
Family
ID=54938965
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| SG11201610799WA SG11201610799WA (en) | 2014-06-27 | 2015-06-29 | Hepcidin and mini-hepcidin analogues and uses therof |
Country Status (10)
| Country | Link |
|---|---|
| US (2) | US20170313754A1 (en) |
| EP (1) | EP3161164A4 (en) |
| JP (1) | JP2017523959A (en) |
| KR (1) | KR20170043509A (en) |
| CN (1) | CN107075574A (en) |
| AU (1) | AU2015279571A1 (en) |
| CA (1) | CA2953721A1 (en) |
| IL (1) | IL249692A0 (en) |
| SG (1) | SG11201610799WA (en) |
| WO (1) | WO2015200916A2 (en) |
Families Citing this family (31)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CA2448382C (en) | 2001-05-25 | 2013-02-19 | Institut National De La Sante Et De La Recherche Medicale (Inserm) | Use of hepcidin as a regulator of iron homeostasis |
| RS62633B1 (en) | 2013-03-15 | 2021-12-31 | Protagonist Therapeutics Inc | Hepcidin analogues and uses thereof |
| US11504346B2 (en) | 2013-11-03 | 2022-11-22 | Arizona Board Of Regents On Behalf Of The University Of Arizona | Redox-activated pro-chelators |
| JP6585162B2 (en) | 2014-05-16 | 2019-10-02 | プロタゴニスト セラピューティクス， インコーポレイテッド | α4β7 integrin thioether peptide antagonist |
| RU2736637C9 (en) | 2014-07-17 | 2021-02-08 | Протагонист Терепьютикс, Инк. | Peptidic interleukin-23 receptor inhibitors for oral administration and use thereof for treating inflammatory intestinal diseases |
| BR112017006826A2 (en) | 2014-10-01 | 2017-12-12 | Protagonist Therapeutics Inc | new antagonist a4ss7 peptide monomers and dimers |
| EP3201217A4 (en) | 2014-10-01 | 2018-07-18 | Protagonist Therapeutics Inc. | Novel cyclic monomer and dimer peptides having integrin antagonist activity |
| US10787490B2 (en) | 2015-07-15 | 2020-09-29 | Protaganist Therapeutics, Inc. | Peptide inhibitors of interleukin-23 receptor and their use to treat inflammatory diseases |
| WO2017117411A1 (en) * | 2015-12-30 | 2017-07-06 | Protagonist Therapeutics, Inc. | Analogues of hepcidin mimetics with improved in vivo half lives |
| BR112018013833A2 (en) * | 2016-01-08 | 2018-12-11 | La Jolla Pharmaceutical Company | hepcidine administration methods |
| US10407468B2 (en) | 2016-03-23 | 2019-09-10 | Protagonist Therapeutics, Inc. | Methods for synthesizing α4β7 peptide antagonists |
| EP3509621A4 (en) * | 2016-09-06 | 2020-06-17 | La Jolla Pharmaceutical Company | Methods of treating iron overload |
| EP3558343A1 (en) * | 2016-12-19 | 2019-10-30 | La Jolla Pharmaceutical Company | Methods of administering hepcidin |
| WO2018128828A1 (en) | 2016-12-23 | 2018-07-12 | Bayer Healthcare Llc | Novel hepcidin mimetics and uses thereof |
| US20200170971A1 (en) * | 2017-07-18 | 2020-06-04 | Arizona Board Of Regents On Behalf Of The University Of Arizona | Disulfide-masked pro-chelator compositions and methods of use |
| EP3681900A4 (en) | 2017-09-11 | 2021-09-08 | Protagonist Therapeutics, Inc. | Opioid agonist peptides and uses thereof |
| CA3089868A1 (en) | 2018-02-08 | 2019-08-15 | Protagonist Therapeutics, Inc. | Conjugated hepcidin mimetics |
| US11286243B2 (en) | 2018-12-13 | 2022-03-29 | Global Blood Therapeutics, Inc. | Ferroportin inhibitors and methods of use |
| PE20220431A1 (en) | 2019-05-07 | 2022-03-29 | Bayer Ag | MASP INHIBITOR COMPOUNDS AND THEIR USES |
| AU2020311395A1 (en) | 2019-07-10 | 2022-02-03 | Protagonist Therapeutics, Inc. | Peptide inhibitors of interleukin-23 receptor and their use to treat inflammatory diseases |
| US20220372099A1 (en) * | 2019-09-03 | 2022-11-24 | Protagonist Therapeutics, Inc. | Conjugated hepcidin mimetics |
| JP2022549506A (en) * | 2019-09-27 | 2022-11-25 | ディスク・メディシン・インコーポレイテッド | Methods for treating myelofibrosis and related conditions |
| US20220372136A1 (en) * | 2019-09-27 | 2022-11-24 | Disc Medicine, Inc. | Methods for treating anemia of chronic disease |
| JP7441955B2 (en) | 2020-01-15 | 2024-03-01 | ヤンセン バイオテツク，インコーポレーテツド | Peptide inhibitors of interleukin-23 receptors and their use for treating inflammatory diseases |
| US20230226074A1 (en) | 2020-04-28 | 2023-07-20 | Global Blood Therapeutics, Inc. | Methods of use for pyrimidines as ferroportin inhibitors |
| KR20230007441A (en) | 2020-04-28 | 2023-01-12 | 글로벌 블러드 테라퓨틱스, 인크. | Cycloalkyl pyrimidines as ferroportin inhibitors |
| US20230159553A1 (en) | 2020-04-28 | 2023-05-25 | Global Blood Therapeutics, Inc | Thieno pyrimidines as ferroportin inhibitors |
| CN111560051B (en) * | 2020-05-26 | 2022-11-25 | 大连工业大学 | Shrimp-derived nonapeptide with iron absorption promoting activity and application thereof |
| AU2021301284A1 (en) * | 2020-07-02 | 2023-02-09 | Tampere University Foundation Sr | Renin-based analysis of hepcidin |
| IL302996A (en) | 2020-11-20 | 2023-07-01 | Janssen Pharmaceutica Nv | Compositions of peptide inhibitors of interleukin-23 receptor |
| WO2024059264A1 (en) * | 2022-09-15 | 2024-03-21 | Migal Galilee Research Institute Ltd | Site-specific activation of regulatory t cells |
Family Cites Families (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| TW201307390A (en) * | 2007-02-02 | 2013-02-16 | Amgen Inc | Hepcidin, hepcidin antagonists and methods of use |
| CN101358201A (en) * | 2007-07-31 | 2009-02-04 | 钱忠明 | Recombinant human iron-regulatory hormone adenovirus, preparation method and application thereof |
| CN101307085B (en) * | 2007-08-01 | 2012-06-13 | 香港理工大学深圳研究院 | SiRNA and recombination lentivirus from preventing hepcidin from regulating protein and uses thereof |
| GR1006896B (en) * | 2007-08-24 | 2010-07-20 | Ελληνικο Ινστιτουτο Παστερ, | A process for producing a peptide hormone. |
| EP2373679B1 (en) * | 2008-12-05 | 2017-03-08 | The Regents of The University of California | Mini-hepcidin peptides and methods of using thereof |
| US20130236977A1 (en) * | 2010-05-24 | 2013-09-12 | Children's Medical Center Corporation | Compositions and methods for plasma peptide analysis |
| AU2012327226C1 (en) * | 2011-12-09 | 2017-03-02 | The Regents Of The University Of California | Modified mini-hepcidin peptides and methods of using thereof |
| RS62633B1 (en) * | 2013-03-15 | 2021-12-31 | Protagonist Therapeutics Inc | Hepcidin analogues and uses thereof |
-
2015
- 2015-06-29 US US15/321,124 patent/US20170313754A1/en not_active Abandoned
- 2015-06-29 WO PCT/US2015/038370 patent/WO2015200916A2/en active Application Filing
- 2015-06-29 JP JP2016575360A patent/JP2017523959A/en not_active Withdrawn
- 2015-06-29 EP EP15812513.8A patent/EP3161164A4/en not_active Withdrawn
- 2015-06-29 CA CA2953721A patent/CA2953721A1/en not_active Abandoned
- 2015-06-29 SG SG11201610799WA patent/SG11201610799WA/en unknown
- 2015-06-29 AU AU2015279571A patent/AU2015279571A1/en not_active Abandoned
- 2015-06-29 CN CN201580043057.2A patent/CN107075574A/en active Pending
- 2015-06-29 KR KR1020177002630A patent/KR20170043509A/en unknown
-
2016
- 2016-12-21 IL IL249692A patent/IL249692A0/en unknown
-
2019
- 2019-06-12 US US16/439,435 patent/US20200017566A1/en not_active Abandoned
Also Published As
| Publication number | Publication date |
|---|---|
| CN107075574A (en) | 2017-08-18 |
| JP2017523959A (en) | 2017-08-24 |
| US20200017566A1 (en) | 2020-01-16 |
| CA2953721A1 (en) | 2015-12-30 |
| KR20170043509A (en) | 2017-04-21 |
| US20170313754A1 (en) | 2017-11-02 |
| AU2015279571A1 (en) | 2017-02-02 |
| EP3161164A2 (en) | 2017-05-03 |
| IL249692A0 (en) | 2017-02-28 |
| EP3161164A4 (en) | 2018-04-25 |
| WO2015200916A2 (en) | 2015-12-30 |
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