JP2017520580A5 - - Google Patents
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- JP2017520580A5 JP2017520580A5 JP2016575734A JP2016575734A JP2017520580A5 JP 2017520580 A5 JP2017520580 A5 JP 2017520580A5 JP 2016575734 A JP2016575734 A JP 2016575734A JP 2016575734 A JP2016575734 A JP 2016575734A JP 2017520580 A5 JP2017520580 A5 JP 2017520580A5
- Authority
- JP
- Japan
- Prior art keywords
- nucleic acid
- transposon
- target nucleic
- target
- transposome
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
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- 150000007523 nucleic acids Chemical class 0.000 claims 77
- 108020004707 nucleic acids Proteins 0.000 claims 74
- 102000039446 nucleic acids Human genes 0.000 claims 74
- 238000000034 method Methods 0.000 claims 38
- 102000008579 Transposases Human genes 0.000 claims 14
- 108010020764 Transposases Proteins 0.000 claims 14
- 238000012163 sequencing technique Methods 0.000 claims 10
- 108020004414 DNA Proteins 0.000 claims 9
- 108091028043 Nucleic acid sequence Proteins 0.000 claims 6
- 239000000523 sample Substances 0.000 claims 6
- 239000000178 monomer Substances 0.000 claims 5
- YBJHBAHKTGYVGT-ZKWXMUAHSA-N (+)-Biotin Chemical compound N1C(=O)N[C@@H]2[C@H](CCCCC(=O)O)SC[C@@H]21 YBJHBAHKTGYVGT-ZKWXMUAHSA-N 0.000 claims 4
- 230000003321 amplification Effects 0.000 claims 4
- 238000003199 nucleic acid amplification method Methods 0.000 claims 4
- 230000000694 effects Effects 0.000 claims 3
- 238000011176 pooling Methods 0.000 claims 3
- 108010034143 Inflammasomes Proteins 0.000 claims 2
- 229960002685 biotin Drugs 0.000 claims 2
- 235000020958 biotin Nutrition 0.000 claims 2
- 239000011616 biotin Substances 0.000 claims 2
- 108090001008 Avidin Proteins 0.000 claims 1
- 102000016928 DNA-directed DNA polymerase Human genes 0.000 claims 1
- 108010014303 DNA-directed DNA polymerase Proteins 0.000 claims 1
- 108010090804 Streptavidin Proteins 0.000 claims 1
- 239000002253 acid Substances 0.000 claims 1
- 125000000217 alkyl group Chemical group 0.000 claims 1
- 125000003277 amino group Chemical group 0.000 claims 1
- 125000003118 aryl group Chemical group 0.000 claims 1
- IVRMZWNICZWHMI-UHFFFAOYSA-N azide group Chemical group [N-]=[N+]=[N-] IVRMZWNICZWHMI-UHFFFAOYSA-N 0.000 claims 1
- 239000002299 complementary DNA Substances 0.000 claims 1
- 238000005034 decoration Methods 0.000 claims 1
- -1 different sequences Chemical class 0.000 claims 1
- 239000000539 dimer Substances 0.000 claims 1
- 239000012634 fragment Substances 0.000 claims 1
- 102000054766 genetic haplotypes Human genes 0.000 claims 1
- 239000002773 nucleotide Substances 0.000 claims 1
- 125000003729 nucleotide group Chemical group 0.000 claims 1
- 125000002467 phosphate group Chemical group [H]OP(=O)(O[H])O[*] 0.000 claims 1
- 125000006850 spacer group Chemical group 0.000 claims 1
- QAOWNCQODCNURD-UHFFFAOYSA-L sulfate group Chemical group S(=O)(=O)([O-])[O-] QAOWNCQODCNURD-UHFFFAOYSA-L 0.000 claims 1
- 125000003396 thiol group Chemical group [H]S* 0.000 claims 1
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201462019209P | 2014-06-30 | 2014-06-30 | |
| US62/019,209 | 2014-06-30 | ||
| PCT/US2015/038050 WO2016003814A1 (en) | 2014-06-30 | 2015-06-26 | Methods and compositions using one-sided transposition |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2017520580A JP2017520580A (ja) | 2017-07-27 |
| JP2017520580A5 true JP2017520580A5 (enExample) | 2018-08-02 |
| JP6652512B2 JP6652512B2 (ja) | 2020-02-26 |
Family
ID=53514440
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2016575734A Active JP6652512B2 (ja) | 2014-06-30 | 2015-06-26 | 片側転移を用いた方法および組成物 |
Country Status (10)
| Country | Link |
|---|---|
| US (5) | US10577603B2 (enExample) |
| EP (1) | EP3161152B1 (enExample) |
| JP (1) | JP6652512B2 (enExample) |
| CN (2) | CN112430641A (enExample) |
| AU (1) | AU2015284464B2 (enExample) |
| CA (1) | CA2953791A1 (enExample) |
| DK (1) | DK3161152T3 (enExample) |
| ES (1) | ES2713153T3 (enExample) |
| SG (1) | SG11201610910QA (enExample) |
| WO (1) | WO2016003814A1 (enExample) |
Families Citing this family (77)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CA2750879C (en) | 2009-01-30 | 2018-05-22 | Oxford Nanopore Technologies Limited | Adaptors for nucleic acid constructs in transmembrane sequencing |
| US10787701B2 (en) | 2010-04-05 | 2020-09-29 | Prognosys Biosciences, Inc. | Spatially encoded biological assays |
| RS54482B1 (sr) | 2010-04-05 | 2016-06-30 | Prognosys Biosciences, Inc. | Biološka testiranja sa prostornim kodiranjem |
| US9957560B2 (en) | 2011-07-25 | 2018-05-01 | Oxford Nanopore Technologies Ltd. | Hairpin loop method for double strand polynucleotide sequencing using transmembrane pores |
| US11155860B2 (en) | 2012-07-19 | 2021-10-26 | Oxford Nanopore Technologies Ltd. | SSB method |
| EP2909337B1 (en) | 2012-10-17 | 2019-01-09 | Spatial Transcriptomics AB | Methods and product for optimising localised or spatial detection of gene expression in a tissue sample |
| BR112015021788B1 (pt) | 2013-03-08 | 2023-02-28 | Oxford Nanopore Technologies Plc | Métodos para mover uma ou mais helicases imobilizadas, para controlar o movimento de um polinucleotídeo alvo, para caracterizar um polinucleotídeo alvo e para controlar o carregamento de uma ou mais helicases em um polinucleotídeo alvo, uso de um poro de transmembrana e de um potencial aplicado e de um ou mais espaçadores, complexo, e, kit |
| GB201314695D0 (en) | 2013-08-16 | 2013-10-02 | Oxford Nanopore Tech Ltd | Method |
| CN105849275B (zh) | 2013-06-25 | 2020-03-17 | 普罗格诺西斯生物科学公司 | 检测样品中生物靶标的空间分布的方法和系统 |
| GB201403096D0 (en) | 2014-02-21 | 2014-04-09 | Oxford Nanopore Tech Ltd | Sample preparation method |
| GB201418159D0 (en) | 2014-10-14 | 2014-11-26 | Oxford Nanopore Tech Ltd | Method |
| EP4119677B1 (en) | 2015-04-10 | 2023-06-28 | Spatial Transcriptomics AB | Spatially distinguished, multiplex nucleic acid analysis of biological specimens |
| US20170283864A1 (en) | 2016-03-31 | 2017-10-05 | Agilent Technologies, Inc. | Use of transposase and y adapters to fragment and tag dna |
| JP7022699B2 (ja) * | 2016-04-19 | 2022-02-18 | カパ バイオシステムズ， インコーポレイテッド | トランスポザーゼ競合物制御系 |
| GB201609220D0 (en) | 2016-05-25 | 2016-07-06 | Oxford Nanopore Tech Ltd | Method |
| US10240196B2 (en) | 2016-05-27 | 2019-03-26 | Agilent Technologies, Inc. | Transposase-random priming DNA sample preparation |
| SG11201811504PA (en) | 2016-07-22 | 2019-01-30 | Univ Oregon Health & Science | Single cell whole genome libraries and combinatorial indexing methods of making thereof |
| EP3452621B1 (en) * | 2017-02-21 | 2022-09-21 | Illumina Inc. | Tagmentation using immobilized transposomes with linkers |
| CN111148846B (zh) | 2017-05-05 | 2024-06-18 | 西比欧生物科学公司 | 在水凝胶中捕获离散生物单元并使其条码化的方法 |
| US10752894B2 (en) * | 2017-05-23 | 2020-08-25 | Bio-Rad Laboratories, Inc. | Molecular barcoding |
| GB201807793D0 (en) | 2018-05-14 | 2018-06-27 | Oxford Nanopore Tech Ltd | Method |
| MX2019015013A (es) | 2018-05-17 | 2021-01-08 | Illumina Inc | Secuenciación de células individuales de alto rendimiento con sesgo de amplificación reducido. |
| US11519033B2 (en) | 2018-08-28 | 2022-12-06 | 10X Genomics, Inc. | Method for transposase-mediated spatial tagging and analyzing genomic DNA in a biological sample |
| EP3859014A4 (en) * | 2018-09-27 | 2022-04-27 | BGI Shenzhen | METHOD OF CONSTRUCTING SEQUENCING LIBRARY, OBTAINED SEQUENCING LIBRARY AND METHOD OF SEQUENCING |
| MX2021003771A (es) | 2018-11-30 | 2021-05-27 | Illumina Inc | Analisis de analitos multiples usando un ensayo unico. |
| US12385083B2 (en) | 2018-12-10 | 2025-08-12 | 10X Genomics, Inc. | Methods of using master / copy arrays for spatial detection |
| CN112867800B (zh) * | 2018-12-17 | 2024-07-12 | Illumina公司 | 用于制备测序文库的方法和手段 |
| US11926867B2 (en) | 2019-01-06 | 2024-03-12 | 10X Genomics, Inc. | Generating capture probes for spatial analysis |
| US11649485B2 (en) | 2019-01-06 | 2023-05-16 | 10X Genomics, Inc. | Generating capture probes for spatial analysis |
| AU2020266530A1 (en) | 2019-04-29 | 2021-04-08 | Illumina, Inc. | Identification and analysis of microbial samples by rapid incubation and nucleic acid enrichment |
| EP3976820A1 (en) | 2019-05-30 | 2022-04-06 | 10X Genomics, Inc. | Methods of detecting spatial heterogeneity of a biological sample |
| SG11202105834UA (en) | 2019-07-12 | 2021-07-29 | Illumina Cambridge Ltd | Nucleic acid library preparation using electrophoresis |
| WO2021011803A1 (en) | 2019-07-16 | 2021-01-21 | Omniome, Inc. | Synthetic nucleic acids having non-natural structures |
| WO2021092433A2 (en) | 2019-11-08 | 2021-05-14 | 10X Genomics, Inc. | Enhancing specificity of analyte binding |
| ES2946357T3 (es) | 2019-12-23 | 2023-07-17 | 10X Genomics Inc | Métodos para el análisis espacial usando ligación con molde de ARN |
| WO2021133842A1 (en) | 2019-12-23 | 2021-07-01 | 10X Genomics, Inc. | Compositions and methods for using fixed biological samples in partition-based assays |
| CN115667507A (zh) | 2019-12-31 | 2023-01-31 | 奇异基因组学系统公司 | 用于长读出测序的多核苷酸条形码 |
| US12365942B2 (en) | 2020-01-13 | 2025-07-22 | 10X Genomics, Inc. | Methods of decreasing background on a spatial array |
| US12405264B2 (en) | 2020-01-17 | 2025-09-02 | 10X Genomics, Inc. | Electrophoretic system and method for analyte capture |
| US11702693B2 (en) | 2020-01-21 | 2023-07-18 | 10X Genomics, Inc. | Methods for printing cells and generating arrays of barcoded cells |
| US11732299B2 (en) | 2020-01-21 | 2023-08-22 | 10X Genomics, Inc. | Spatial assays with perturbed cells |
| US20210230681A1 (en) | 2020-01-24 | 2021-07-29 | 10X Genomics, Inc. | Methods for spatial analysis using proximity ligation |
| US12076701B2 (en) | 2020-01-31 | 2024-09-03 | 10X Genomics, Inc. | Capturing oligonucleotides in spatial transcriptomics |
| US12110541B2 (en) | 2020-02-03 | 2024-10-08 | 10X Genomics, Inc. | Methods for preparing high-resolution spatial arrays |
| US11898205B2 (en) | 2020-02-03 | 2024-02-13 | 10X Genomics, Inc. | Increasing capture efficiency of spatial assays |
| US11732300B2 (en) | 2020-02-05 | 2023-08-22 | 10X Genomics, Inc. | Increasing efficiency of spatial analysis in a biological sample |
| US12129516B2 (en) | 2020-02-07 | 2024-10-29 | 10X Genomics, Inc. | Quantitative and automated permeabilization performance evaluation for spatial transcriptomics |
| IL294909A (en) | 2020-02-13 | 2022-09-01 | Zymergen Inc | Metagenomic library and natural product discovery platform |
| US12281357B1 (en) | 2020-02-14 | 2025-04-22 | 10X Genomics, Inc. | In situ spatial barcoding |
| US11891654B2 (en) | 2020-02-24 | 2024-02-06 | 10X Genomics, Inc. | Methods of making gene expression libraries |
| ES2965354T3 (es) | 2020-04-22 | 2024-04-12 | 10X Genomics Inc | Métodos para análisis espacial que usan eliminación de ARN elegido como diana |
| EP4553168A3 (en) | 2020-05-22 | 2025-08-27 | 10x Genomics, Inc. | Spatial analysis to detect sequence variants |
| EP4153775B1 (en) | 2020-05-22 | 2024-07-24 | 10X Genomics, Inc. | Simultaneous spatio-temporal measurement of gene expression and cellular activity |
| WO2021242834A1 (en) | 2020-05-26 | 2021-12-02 | 10X Genomics, Inc. | Method for resetting an array |
| US12031177B1 (en) | 2020-06-04 | 2024-07-09 | 10X Genomics, Inc. | Methods of enhancing spatial resolution of transcripts |
| WO2021252499A1 (en) | 2020-06-08 | 2021-12-16 | 10X Genomics, Inc. | Methods of determining a surgical margin and methods of use thereof |
| EP4446430A3 (en) | 2020-06-10 | 2024-12-18 | 10X Genomics, Inc. | Methods for determining a location of an analyte in a biological sample |
| CN116034166A (zh) | 2020-06-25 | 2023-04-28 | 10X基因组学有限公司 | Dna甲基化的空间分析 |
| US11981960B1 (en) | 2020-07-06 | 2024-05-14 | 10X Genomics, Inc. | Spatial analysis utilizing degradable hydrogels |
| US12209280B1 (en) | 2020-07-06 | 2025-01-28 | 10X Genomics, Inc. | Methods of identifying abundance and location of an analyte in a biological sample using second strand synthesis |
| US11761038B1 (en) | 2020-07-06 | 2023-09-19 | 10X Genomics, Inc. | Methods for identifying a location of an RNA in a biological sample |
| US11981958B1 (en) | 2020-08-20 | 2024-05-14 | 10X Genomics, Inc. | Methods for spatial analysis using DNA capture |
| US11926822B1 (en) | 2020-09-23 | 2024-03-12 | 10X Genomics, Inc. | Three-dimensional spatial analysis |
| US11827935B1 (en) | 2020-11-19 | 2023-11-28 | 10X Genomics, Inc. | Methods for spatial analysis using rolling circle amplification and detection probes |
| AU2021409136A1 (en) | 2020-12-21 | 2023-06-29 | 10X Genomics, Inc. | Methods, compositions, and systems for capturing probes and/or barcodes |
| AU2022245985A1 (en) * | 2021-03-22 | 2023-09-21 | Illumina Cambridge Limited | Methods for improving nucleic acid cluster clonality |
| EP4428246B1 (en) | 2021-04-14 | 2025-12-24 | 10X Genomics, Inc. | Methods of measuring mislocalization of an analyte |
| WO2022233821A1 (en) * | 2021-05-03 | 2022-11-10 | European Molecular Biology Laboratory | Methods for isolating and/or obtaining captured polynucleotide fragments |
| WO2022236054A1 (en) | 2021-05-06 | 2022-11-10 | 10X Genomics, Inc. | Methods for increasing resolution of spatial analysis |
| WO2022256503A1 (en) | 2021-06-03 | 2022-12-08 | 10X Genomics, Inc. | Methods, compositions, kits, and systems for enhancing analyte capture for spatial analysis |
| EP4509614A3 (en) | 2021-09-01 | 2025-05-14 | 10X Genomics, Inc. | Methods, compositions, and kits for blocking a capture probe on a spatial array |
| EP4419707A1 (en) | 2021-11-10 | 2024-08-28 | 10X Genomics, Inc. | Methods, compositions, and kits for determining the location of an analyte in a biological sample |
| WO2023102118A2 (en) | 2021-12-01 | 2023-06-08 | 10X Genomics, Inc. | Methods, compositions, and systems for improved in situ detection of analytes and spatial analysis |
| WO2023122755A2 (en) * | 2021-12-23 | 2023-06-29 | Illumina Cambridge Limited | Flow cells and methods |
| EP4272764A1 (en) | 2022-05-03 | 2023-11-08 | Scipio Bioscience | Method of complexing biological units with particles |
| US20250320487A1 (en) * | 2022-05-18 | 2025-10-16 | Illumina, Inc. | Preparation Of Size-Controlled Nucleic Acid Fragments |
| WO2025129074A2 (en) | 2023-12-14 | 2025-06-19 | Illumina, Inc. | Indexing techniques for tagmented dna libraries |
Family Cites Families (93)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CA1323293C (en) | 1987-12-11 | 1993-10-19 | Keith C. Backman | Assay using template-dependent nucleic acid probe reorganization |
| GB8810400D0 (en) | 1988-05-03 | 1988-06-08 | Southern E | Analysing polynucleotide sequences |
| CA1341584C (en) | 1988-04-06 | 2008-11-18 | Bruce Wallace | Method of amplifying and detecting nucleic acid sequences |
| AU3539089A (en) | 1988-04-08 | 1989-11-03 | Salk Institute For Biological Studies, The | Ligase-based amplification method |
| US5130238A (en) | 1988-06-24 | 1992-07-14 | Cangene Corporation | Enhanced nucleic acid amplification process |
| ATE144556T1 (de) | 1988-06-24 | 1996-11-15 | Amgen Inc | Verfahren und mittel zum nachweis von nukleinsäuresequenzen |
| EP0425563B1 (en) | 1988-07-20 | 1996-05-15 | David Segev | Process for amplifying and detecting nucleic acid sequences |
| US5185243A (en) | 1988-08-25 | 1993-02-09 | Syntex (U.S.A.) Inc. | Method for detection of specific nucleic acid sequences |
| EP0450060A1 (en) | 1989-10-26 | 1991-10-09 | Sri International | Dna sequencing |
| US5573907A (en) | 1990-01-26 | 1996-11-12 | Abbott Laboratories | Detecting and amplifying target nucleic acids using exonucleolytic activity |
| EP0439182B1 (en) | 1990-01-26 | 1996-04-24 | Abbott Laboratories | Improved method of amplifying target nucleic acids applicable to both polymerase and ligase chain reactions |
| US5223414A (en) | 1990-05-07 | 1993-06-29 | Sri International | Process for nucleic acid hybridization and amplification |
| US5455166A (en) | 1991-01-31 | 1995-10-03 | Becton, Dickinson And Company | Strand displacement amplification |
| ATE247716T1 (de) | 1994-02-07 | 2003-09-15 | Beckman Coulter Inc | Ligase/polymerase-vermittelte analyse genetischer elemente von einzelnukleotid-polymorphismen und ihre verwendung in der genetischen analyse |
| US5677170A (en) | 1994-03-02 | 1997-10-14 | The Johns Hopkins University | In vitro transposition of artificial transposons |
| JPH09510351A (ja) | 1994-03-16 | 1997-10-21 | ジェン−プローブ・インコーポレイテッド | 等温鎖置換核酸増幅法 |
| US5552278A (en) | 1994-04-04 | 1996-09-03 | Spectragen, Inc. | DNA sequencing by stepwise ligation and cleavage |
| US5641658A (en) | 1994-08-03 | 1997-06-24 | Mosaic Technologies, Inc. | Method for performing amplification of nucleic acid with two primers bound to a single solid support |
| EP0796341B1 (en) | 1994-12-09 | 1998-09-23 | Imperial College Innovations Limited | Identification of genes which allow a microorganism to adapt to a particular environment |
| US5750341A (en) | 1995-04-17 | 1998-05-12 | Lynx Therapeutics, Inc. | DNA sequencing by parallel oligonucleotide extensions |
| US5925545A (en) | 1996-09-09 | 1999-07-20 | Wisconsin Alumni Research Foundation | System for in vitro transposition |
| US5965443A (en) | 1996-09-09 | 1999-10-12 | Wisconsin Alumni Research Foundation | System for in vitro transposition |
| GB9620209D0 (en) | 1996-09-27 | 1996-11-13 | Cemu Bioteknik Ab | Method of sequencing DNA |
| GB9626815D0 (en) | 1996-12-23 | 1997-02-12 | Cemu Bioteknik Ab | Method of sequencing DNA |
| ATE364718T1 (de) | 1997-04-01 | 2007-07-15 | Solexa Ltd | Verfahren zur vervielfältigung von nukleinsäure |
| ATE269908T1 (de) | 1997-04-01 | 2004-07-15 | Manteia S A | Methode zur sequenzierung von nukleinsäuren |
| FI103809B (fi) | 1997-07-14 | 1999-09-30 | Finnzymes Oy | In vitro -menetelmä templaattien tuottamiseksi DNA-sekventointia varten |
| AR021833A1 (es) | 1998-09-30 | 2002-08-07 | Applied Research Systems | Metodos de amplificacion y secuenciacion de acido nucleico |
| US20050244870A1 (en) | 1999-04-20 | 2005-11-03 | Illumina, Inc. | Nucleic acid sequencing using microsphere arrays |
| US6274320B1 (en) | 1999-09-16 | 2001-08-14 | Curagen Corporation | Method of sequencing a nucleic acid |
| US7244559B2 (en) | 1999-09-16 | 2007-07-17 | 454 Life Sciences Corporation | Method of sequencing a nucleic acid |
| US7955794B2 (en) | 2000-09-21 | 2011-06-07 | Illumina, Inc. | Multiplex nucleic acid reactions |
| US7611869B2 (en) | 2000-02-07 | 2009-11-03 | Illumina, Inc. | Multiplexed methylation detection methods |
| US7582420B2 (en) | 2001-07-12 | 2009-09-01 | Illumina, Inc. | Multiplex nucleic acid reactions |
| US7001792B2 (en) | 2000-04-24 | 2006-02-21 | Eagle Research & Development, Llc | Ultra-fast nucleic acid sequencing device and a method for making and using the same |
| CA2415897A1 (en) | 2000-07-07 | 2002-01-17 | Susan H. Hardin | Real-time sequence determination |
| US7211414B2 (en) | 2000-12-01 | 2007-05-01 | Visigen Biotechnologies, Inc. | Enzymatic nucleic acid synthesis: compositions and methods for altering monomer incorporation fidelity |
| AR031640A1 (es) | 2000-12-08 | 2003-09-24 | Applied Research Systems | Amplificacion isotermica de acidos nucleicos en un soporte solido |
| US20040110191A1 (en) | 2001-01-31 | 2004-06-10 | Winkler Matthew M. | Comparative analysis of nucleic acids using population tagging |
| US7138267B1 (en) | 2001-04-04 | 2006-11-21 | Epicentre Technologies Corporation | Methods and compositions for amplifying DNA clone copy number |
| WO2003031629A1 (en) * | 2001-10-09 | 2003-04-17 | Copyrat Pty Ltd | Methods of preparing a targeting vector and uses thereof |
| US7057026B2 (en) | 2001-12-04 | 2006-06-06 | Solexa Limited | Labelled nucleotides |
| US7399590B2 (en) | 2002-02-21 | 2008-07-15 | Asm Scientific, Inc. | Recombinase polymerase amplification |
| US20040002090A1 (en) | 2002-03-05 | 2004-01-01 | Pascal Mayer | Methods for detecting genome-wide sequence variations associated with a phenotype |
| GB2395954A (en) | 2002-08-23 | 2004-06-09 | Solexa Ltd | Modified nucleotides |
| US7595883B1 (en) | 2002-09-16 | 2009-09-29 | The Board Of Trustees Of The Leland Stanford Junior University | Biological analysis arrangement and approach therefor |
| US7083980B2 (en) | 2003-04-17 | 2006-08-01 | Wisconsin Alumni Research Foundation | Tn5 transposase mutants and the use thereof |
| JP2007525963A (ja) | 2003-06-20 | 2007-09-13 | イルミナ インコーポレイテッド | 全ゲノム増幅および遺伝型決定のための方法および組成物 |
| EP1682680B2 (en) | 2003-10-31 | 2018-03-21 | AB Advanced Genetic Analysis Corporation | Methods for producing a paired tag from a nucleic acid sequence and methods of use thereof |
| EP1701785A1 (en) | 2004-01-07 | 2006-09-20 | Solexa Ltd. | Modified molecular arrays |
| US7595160B2 (en) | 2004-01-13 | 2009-09-29 | U.S. Genomics, Inc. | Analyte detection using barcoded polymers |
| WO2005100585A2 (en) | 2004-03-30 | 2005-10-27 | Epicentre | Methods for obtaining directionally truncated polypeptides |
| US7608434B2 (en) | 2004-08-04 | 2009-10-27 | Wisconsin Alumni Research Foundation | Mutated Tn5 transposase proteins and the use thereof |
| EP1790202A4 (en) | 2004-09-17 | 2013-02-20 | Pacific Biosciences California | APPARATUS AND METHOD FOR ANALYZING MOLECULES |
| US7405281B2 (en) | 2005-09-29 | 2008-07-29 | Pacific Biosciences Of California, Inc. | Fluorescent nucleotide analogs and uses therefor |
| GB0522310D0 (en) | 2005-11-01 | 2005-12-07 | Solexa Ltd | Methods of preparing libraries of template polynucleotides |
| US20070128610A1 (en) | 2005-12-02 | 2007-06-07 | Buzby Philip R | Sample preparation method and apparatus for nucleic acid sequencing |
| US7537897B2 (en) | 2006-01-23 | 2009-05-26 | Population Genetics Technologies, Ltd. | Molecular counting |
| US20080009420A1 (en) | 2006-03-17 | 2008-01-10 | Schroth Gary P | Isothermal methods for creating clonal single molecule arrays |
| EP3722409A1 (en) | 2006-03-31 | 2020-10-14 | Illumina, Inc. | Systems and devices for sequence by synthesis analysis |
| EP2038429B1 (en) | 2006-06-30 | 2013-08-21 | Nugen Technologies, Inc. | Methods for fragmentation and labeling of nucleic acids |
| US7754429B2 (en) | 2006-10-06 | 2010-07-13 | Illumina Cambridge Limited | Method for pair-wise sequencing a plurity of target polynucleotides |
| WO2008051530A2 (en) | 2006-10-23 | 2008-05-02 | Pacific Biosciences Of California, Inc. | Polymerase enzymes and reagents for enhanced nucleic acid sequencing |
| CA2672315A1 (en) | 2006-12-14 | 2008-06-26 | Ion Torrent Systems Incorporated | Methods and apparatus for measuring analytes using large scale fet arrays |
| US8349167B2 (en) | 2006-12-14 | 2013-01-08 | Life Technologies Corporation | Methods and apparatus for detecting molecular interactions using FET arrays |
| US8262900B2 (en) | 2006-12-14 | 2012-09-11 | Life Technologies Corporation | Methods and apparatus for measuring analytes using large scale FET arrays |
| JP2010535513A (ja) | 2007-08-15 | 2010-11-25 | ザ ユニバーシティ オブ ホンコン | 高スループット亜硫酸水素ｄｎａシークエンシングのための方法および組成物ならびに有用性 |
| US8383345B2 (en) | 2008-09-12 | 2013-02-26 | University Of Washington | Sequence tag directed subassembly of short sequencing reads into long sequencing reads |
| US20100137143A1 (en) | 2008-10-22 | 2010-06-03 | Ion Torrent Systems Incorporated | Methods and apparatus for measuring analytes |
| US9080211B2 (en) | 2008-10-24 | 2015-07-14 | Epicentre Technologies Corporation | Transposon end compositions and methods for modifying nucleic acids |
| HUE027961T2 (en) * | 2008-10-24 | 2016-11-28 | Epicentre Tech Corp | Transposon final preparations and methods for modifying nucleic acids |
| CN102421902A (zh) | 2009-02-25 | 2012-04-18 | 约翰·霍普金斯大学 | Piggybac转座子变异及其使用方法 |
| US8148515B1 (en) | 2009-06-02 | 2012-04-03 | Biotium, Inc. | Detection using a dye and a dye modifier |
| US20110224106A1 (en) * | 2010-03-10 | 2011-09-15 | Ibis Biosciences, Inc. | Production Of Single-Stranded Circular Nucleic Acid |
| US9029103B2 (en) | 2010-08-27 | 2015-05-12 | Illumina Cambridge Limited | Methods for sequencing polynucleotides |
| WO2012058096A1 (en) | 2010-10-27 | 2012-05-03 | Illumina, Inc. | Microdevices and biosensor cartridges for biological or chemical analysis and systems and methods for the same |
| US8829171B2 (en) | 2011-02-10 | 2014-09-09 | Illumina, Inc. | Linking sequence reads using paired code tags |
| US9074251B2 (en) | 2011-02-10 | 2015-07-07 | Illumina, Inc. | Linking sequence reads using paired code tags |
| EP2635679B1 (en) | 2010-11-05 | 2017-04-19 | Illumina, Inc. | Linking sequence reads using paired code tags |
| US8951781B2 (en) | 2011-01-10 | 2015-02-10 | Illumina, Inc. | Systems, methods, and apparatuses to image a sample for biological or chemical analysis |
| ES2762866T3 (es) * | 2011-01-28 | 2020-05-26 | Illumina Inc | Reemplazo de nucleótidos por bibliotecas doblemente etiquetadas y direccionales |
| US10457936B2 (en) * | 2011-02-02 | 2019-10-29 | University Of Washington Through Its Center For Commercialization | Massively parallel contiguity mapping |
| EP2710172B1 (en) * | 2011-05-20 | 2017-03-29 | Fluidigm Corporation | Nucleic acid encoding reactions |
| US9005935B2 (en) * | 2011-05-23 | 2015-04-14 | Agilent Technologies, Inc. | Methods and compositions for DNA fragmentation and tagging by transposases |
| US20130017978A1 (en) * | 2011-07-11 | 2013-01-17 | Finnzymes Oy | Methods and transposon nucleic acids for generating a dna library |
| NO2694769T3 (enExample) * | 2012-03-06 | 2018-03-03 | ||
| US9012022B2 (en) | 2012-06-08 | 2015-04-21 | Illumina, Inc. | Polymer coatings |
| CN105188767A (zh) | 2012-07-25 | 2015-12-23 | 布罗德研究所有限公司 | 可诱导的dna结合蛋白和基因组干扰工具及其应用 |
| US9644199B2 (en) * | 2012-10-01 | 2017-05-09 | Agilent Technologies, Inc. | Immobilized transposase complexes for DNA fragmentation and tagging |
| US9683230B2 (en) | 2013-01-09 | 2017-06-20 | Illumina Cambridge Limited | Sample preparation on a solid support |
| EP2970951B1 (en) | 2013-03-13 | 2019-02-20 | Illumina, Inc. | Methods for nucleic acid sequencing |
| US10100355B2 (en) * | 2013-12-09 | 2018-10-16 | Illumina, Inc. | Methods and compositions for targeted nucleic acid sequencing |
| EP3845640A3 (en) | 2014-04-15 | 2021-09-01 | Illumina, Inc. | Modified tranposases for improved insertion sequence bias and increased dna input tolerence |
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