JP2017511698A5 - - Google Patents
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- JP2017511698A5 JP2017511698A5 JP2016553385A JP2016553385A JP2017511698A5 JP 2017511698 A5 JP2017511698 A5 JP 2017511698A5 JP 2016553385 A JP2016553385 A JP 2016553385A JP 2016553385 A JP2016553385 A JP 2016553385A JP 2017511698 A5 JP2017511698 A5 JP 2017511698A5
- Authority
- JP
- Japan
- Prior art keywords
- probe
- seq
- nos
- her2
- control
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 239000000523 sample Substances 0.000 claims 39
- 101001012157 Homo sapiens Receptor tyrosine-protein kinase erbB-2 Proteins 0.000 claims 11
- 102100030086 Receptor tyrosine-protein kinase erbB-2 Human genes 0.000 claims 11
- 238000000034 method Methods 0.000 claims 10
- 210000003917 human chromosome Anatomy 0.000 claims 8
- 210000001519 tissue Anatomy 0.000 claims 8
- 210000004940 nucleus Anatomy 0.000 claims 6
- 101100495913 Arabidopsis thaliana CHR17 gene Proteins 0.000 claims 5
- 238000007901 in situ hybridization Methods 0.000 claims 4
- 210000000349 chromosome Anatomy 0.000 claims 3
- 241000576133 Alphasatellites Species 0.000 claims 2
- 101150054472 HER2 gene Proteins 0.000 claims 2
- 230000000295 complement effect Effects 0.000 claims 2
- 108700020302 erbB-2 Genes Proteins 0.000 claims 2
- 239000000178 monomer Substances 0.000 claims 2
- 239000002773 nucleotide Substances 0.000 claims 2
- 125000003729 nucleotide group Chemical group 0.000 claims 2
- 238000010186 staining Methods 0.000 claims 2
- 206010028980 Neoplasm Diseases 0.000 claims 1
- 108091034117 Oligonucleotide Proteins 0.000 claims 1
- 239000003086 colorant Substances 0.000 claims 1
- 230000004154 complement system Effects 0.000 claims 1
- 238000001514 detection method Methods 0.000 claims 1
- 239000000975 dye Substances 0.000 claims 1
- 238000011065 in-situ storage Methods 0.000 claims 1
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201461943196P | 2014-02-21 | 2014-02-21 | |
| US61/943,196 | 2014-02-21 | ||
| US201462094543P | 2014-12-19 | 2014-12-19 | |
| US62/094,543 | 2014-12-19 | ||
| PCT/EP2015/053555 WO2015124702A1 (en) | 2014-02-21 | 2015-02-20 | Single-stranded oligonucleotide probes for chromosome or gene copy enumeration |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2020002295A Division JP2020089374A (ja) | 2014-02-21 | 2020-01-09 | 染色体又は遺伝子コピーの計数のための一本鎖オリゴヌクレオチドプローブ |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2017511698A JP2017511698A (ja) | 2017-04-27 |
| JP2017511698A5 true JP2017511698A5 (enExample) | 2018-03-29 |
| JP6982392B2 JP6982392B2 (ja) | 2021-12-17 |
Family
ID=52574155
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2016553385A Active JP6982392B2 (ja) | 2014-02-21 | 2015-02-20 | 染色体又は遺伝子コピーの計数のための一本鎖オリゴヌクレオチドプローブ |
| JP2020002295A Pending JP2020089374A (ja) | 2014-02-21 | 2020-01-09 | 染色体又は遺伝子コピーの計数のための一本鎖オリゴヌクレオチドプローブ |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2020002295A Pending JP2020089374A (ja) | 2014-02-21 | 2020-01-09 | 染色体又は遺伝子コピーの計数のための一本鎖オリゴヌクレオチドプローブ |
Country Status (8)
| Country | Link |
|---|---|
| US (3) | US10752955B2 (enExample) |
| EP (1) | EP3108006B1 (enExample) |
| JP (2) | JP6982392B2 (enExample) |
| AU (1) | AU2015220749B2 (enExample) |
| CA (1) | CA2940111C (enExample) |
| DK (1) | DK3108006T3 (enExample) |
| ES (1) | ES2689568T3 (enExample) |
| WO (1) | WO2015124702A1 (enExample) |
Families Citing this family (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AU2015326827B2 (en) * | 2014-10-02 | 2019-11-07 | Ventana Medical Systems, Inc. | Polymers and conjugates comprising the same |
| EP3710820B1 (en) | 2017-11-13 | 2025-06-11 | F. Hoffmann-La Roche AG | Devices for sample analysis using epitachophoresis |
| WO2020074742A1 (en) | 2018-10-12 | 2020-04-16 | F. Hoffmann-La Roche Ag | Detection methods for epitachophoresis workflow automation |
| WO2020229437A1 (en) | 2019-05-14 | 2020-11-19 | F. Hoffmann-La Roche Ag | Devices and methods for sample analysis |
| CN111411146B (zh) * | 2020-03-31 | 2024-01-16 | 宜昌美光硅谷生命科技股份有限公司 | 一种检测和定量单拷贝染色体外dna或rna的方法 |
| CN112795649A (zh) * | 2021-01-05 | 2021-05-14 | 武汉友芝友医疗科技股份有限公司 | 一种用于检测her2基因扩增水平的探针组及其应用 |
| CN114214318A (zh) * | 2021-11-30 | 2022-03-22 | 广州康立明生物科技股份有限公司 | 一种染色体着丝粒探针 |
| CN121368715A (zh) | 2023-04-13 | 2026-01-20 | 文塔纳医疗系统公司 | 用于固定的实体瘤的增殖测定 |
| WO2025193604A1 (en) | 2024-03-11 | 2025-09-18 | Ventana Medical Systems, Inc. | Non-enzymatic dissociation of ffpe tissue and generation of single cells with intact cell surface markers |
Family Cites Families (18)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5447841A (en) | 1986-01-16 | 1995-09-05 | The Regents Of The Univ. Of California | Methods for chromosome-specific staining |
| EP0511750A1 (en) * | 1991-04-09 | 1992-11-04 | The Regents Of The University Of California | Repeat sequence chromosome specific nucleic acid probes |
| US5750340A (en) * | 1995-04-07 | 1998-05-12 | University Of New Mexico | In situ hybridization solution and process |
| US6046004A (en) | 1997-02-27 | 2000-04-04 | Lorne Park Research, Inc. | Solution hybridization of nucleic acids with antisense probes having modified backbones |
| US6573043B1 (en) * | 1998-10-07 | 2003-06-03 | Genentech, Inc. | Tissue analysis and kits therefor |
| US20020081590A1 (en) * | 2000-02-04 | 2002-06-27 | Aeomica, Inc. | Methods and apparatus for predicting, confirming, and displaying functional information derived from genomic sequence |
| US20030017491A1 (en) * | 2000-09-14 | 2003-01-23 | Zuo-Rong Shi | Chromogenic in situ hybridization methods, kits, and compositions |
| US20020160401A1 (en) | 2001-03-29 | 2002-10-31 | Yasuyuki Nozaki | Biochip and method of designing probes |
| JP2002296279A (ja) * | 2001-03-29 | 2002-10-09 | Hitachi Software Eng Co Ltd | バイオチップ及びプローブ設計方法 |
| WO2007087612A2 (en) * | 2006-01-25 | 2007-08-02 | Board Of Regents, The University Of Texas System | Detection and diagnosis of smoking related cancers |
| US7807356B2 (en) | 2006-03-09 | 2010-10-05 | Agilent Technologies, Inc. | Labeled nucleotide composition |
| JP5126644B2 (ja) * | 2006-05-31 | 2013-01-23 | 独立行政法人産業技術総合研究所 | 遺伝子発現プロファイルを用いた漢方薬の評価法 |
| US20080299555A1 (en) * | 2007-05-30 | 2008-12-04 | Hiroaki Nitta | Multicolor chromogenic detection of biomarkers |
| WO2010033508A1 (en) * | 2008-09-16 | 2010-03-25 | Historx, Inc. | Reproducible quantification of biomarker expression |
| DK2459743T3 (da) | 2009-07-30 | 2017-11-06 | Hoffmann La Roche | Sæt af oligonukleotidprober såvel som fremgangsmåder og anvendelser relateret dertil |
| WO2012049211A1 (en) * | 2010-10-12 | 2012-04-19 | Universite Libre De Bruxelles | Bach2 repression in cells |
| CA2838736A1 (en) * | 2011-06-07 | 2012-12-13 | Caris Mpi, Inc. | Molecular profiling for cancer |
| US10510435B2 (en) * | 2013-04-30 | 2019-12-17 | California Institute Of Technology | Error correction of multiplex imaging analysis by sequential hybridization |
-
2015
- 2015-02-20 CA CA2940111A patent/CA2940111C/en active Active
- 2015-02-20 WO PCT/EP2015/053555 patent/WO2015124702A1/en not_active Ceased
- 2015-02-20 JP JP2016553385A patent/JP6982392B2/ja active Active
- 2015-02-20 AU AU2015220749A patent/AU2015220749B2/en active Active
- 2015-02-20 ES ES15705997.3T patent/ES2689568T3/es active Active
- 2015-02-20 EP EP15705997.3A patent/EP3108006B1/en active Active
- 2015-02-20 DK DK15705997.3T patent/DK3108006T3/en active
-
2016
- 2016-08-19 US US15/242,471 patent/US10752955B2/en active Active
-
2020
- 2020-01-09 JP JP2020002295A patent/JP2020089374A/ja active Pending
- 2020-05-20 US US16/879,228 patent/US11788149B2/en active Active
-
2023
- 2023-08-29 US US18/458,024 patent/US20240084395A1/en active Pending
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