DK3108006T3 - SINGLE-STRENGTHED OIGONUCLEOTIDE PRINCIPLES FOR CHROMOSOME OR RE-COPY COUNTING - Google Patents
SINGLE-STRENGTHED OIGONUCLEOTIDE PRINCIPLES FOR CHROMOSOME OR RE-COPY COUNTING Download PDFInfo
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- DK3108006T3 DK3108006T3 DK15705997.3T DK15705997T DK3108006T3 DK 3108006 T3 DK3108006 T3 DK 3108006T3 DK 15705997 T DK15705997 T DK 15705997T DK 3108006 T3 DK3108006 T3 DK 3108006T3
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- Prior art keywords
- probe
- her2
- probes
- hybridization
- chr17
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- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
- C12Q1/6883—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
- C12Q1/6886—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material for cancer
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- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6813—Hybridisation assays
- C12Q1/6841—In situ hybridisation
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- C12Q2600/156—Polymorphic or mutational markers
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- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
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- C12Q2600/00—Oligonucleotides characterized by their use
- C12Q2600/158—Expression markers
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| PCT/EP2015/053555 WO2015124702A1 (en) | 2014-02-21 | 2015-02-20 | Single-stranded oligonucleotide probes for chromosome or gene copy enumeration |
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| WO2016050913A2 (en) * | 2014-10-02 | 2016-04-07 | Ventana Medical Systems, Inc. | Polymers and conjugates comprising the same |
| US11691141B2 (en) | 2017-11-13 | 2023-07-04 | Roche Sequencing Solutions, Inc. | Devices for sample analysis using epitachophoresis |
| WO2020074742A1 (en) | 2018-10-12 | 2020-04-16 | F. Hoffmann-La Roche Ag | Detection methods for epitachophoresis workflow automation |
| WO2020229437A1 (en) | 2019-05-14 | 2020-11-19 | F. Hoffmann-La Roche Ag | Devices and methods for sample analysis |
| CN111411146B (zh) * | 2020-03-31 | 2024-01-16 | 宜昌美光硅谷生命科技股份有限公司 | 一种检测和定量单拷贝染色体外dna或rna的方法 |
| CN112795649A (zh) * | 2021-01-05 | 2021-05-14 | 武汉友芝友医疗科技股份有限公司 | 一种用于检测her2基因扩增水平的探针组及其应用 |
| CN114214318A (zh) * | 2021-11-30 | 2022-03-22 | 广州康立明生物科技股份有限公司 | 一种染色体着丝粒探针 |
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| WO2025193604A1 (en) | 2024-03-11 | 2025-09-18 | Ventana Medical Systems, Inc. | Non-enzymatic dissociation of ffpe tissue and generation of single cells with intact cell surface markers |
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| US5447841A (en) | 1986-01-16 | 1995-09-05 | The Regents Of The Univ. Of California | Methods for chromosome-specific staining |
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| US5750340A (en) * | 1995-04-07 | 1998-05-12 | University Of New Mexico | In situ hybridization solution and process |
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| AU3087801A (en) * | 2000-02-04 | 2001-08-14 | Molecular Dynamics Inc | Human genome-derived single exon nucleic acid probes useful for analysis of geneexpression in human breast and hbl 100 cells |
| US20030017491A1 (en) | 2000-09-14 | 2003-01-23 | Zuo-Rong Shi | Chromogenic in situ hybridization methods, kits, and compositions |
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| EP1989329A2 (en) * | 2006-01-25 | 2008-11-12 | Board of Regents, The University of Texas System | Detection and diagnosis of smoking related cancers |
| US7807356B2 (en) | 2006-03-09 | 2010-10-05 | Agilent Technologies, Inc. | Labeled nucleotide composition |
| JP5126644B2 (ja) * | 2006-05-31 | 2013-01-23 | 独立行政法人産業技術総合研究所 | 遺伝子発現プロファイルを用いた漢方薬の評価法 |
| US20080299555A1 (en) * | 2007-05-30 | 2008-12-04 | Hiroaki Nitta | Multicolor chromogenic detection of biomarkers |
| AU2009293380B2 (en) * | 2008-09-16 | 2016-05-19 | Novartis Ag | Reproducible quantification of biomarker expression |
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| WO2012170715A1 (en) * | 2011-06-07 | 2012-12-13 | Caris Mpi, Inc. | Molecular profiling for cancer |
| US10510435B2 (en) * | 2013-04-30 | 2019-12-17 | California Institute Of Technology | Error correction of multiplex imaging analysis by sequential hybridization |
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