AU2015220749B2 - Single-stranded oligonucleotide probes for chromosome or gene copy enumeration - Google Patents

Single-stranded oligonucleotide probes for chromosome or gene copy enumeration Download PDF

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Publication number
AU2015220749B2
AU2015220749B2 AU2015220749A AU2015220749A AU2015220749B2 AU 2015220749 B2 AU2015220749 B2 AU 2015220749B2 AU 2015220749 A AU2015220749 A AU 2015220749A AU 2015220749 A AU2015220749 A AU 2015220749A AU 2015220749 B2 AU2015220749 B2 AU 2015220749B2
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her2
probe
probes
chr17
hybridization
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AU2015220749A1 (en
Inventor
Michael Farrell
Antony HUBBARD
Donald Johnson
Brian D. Kelly
Taylor SHINGLER
Lei Tang
Wenjun Zhang
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Ventana Medical Systems Inc
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Ventana Medical Systems Inc
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    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
    • C12Q1/6883—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
    • C12Q1/6886—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material for cancer
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6813—Hybridisation assays
    • C12Q1/6841—In situ hybridisation
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00—Oligonucleotides characterized by their use
    • C12Q2600/156—Polymorphic or mutational markers
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00—Oligonucleotides characterized by their use
    • C12Q2600/158—Expression markers

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  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Engineering & Computer Science (AREA)
  • Immunology (AREA)
  • Genetics & Genomics (AREA)
  • Analytical Chemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Biotechnology (AREA)
  • Microbiology (AREA)
  • Biochemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Molecular Biology (AREA)
  • Biophysics (AREA)
  • Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Hospice & Palliative Care (AREA)
  • Oncology (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
AU2015220749A 2014-02-21 2015-02-20 Single-stranded oligonucleotide probes for chromosome or gene copy enumeration Active AU2015220749B2 (en)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US201461943196P 2014-02-21 2014-02-21
US61/943,196 2014-02-21
US201462094543P 2014-12-19 2014-12-19
US62/094,543 2014-12-19
PCT/EP2015/053555 WO2015124702A1 (en) 2014-02-21 2015-02-20 Single-stranded oligonucleotide probes for chromosome or gene copy enumeration

Publications (2)

Publication Number Publication Date
AU2015220749A1 AU2015220749A1 (en) 2016-07-07
AU2015220749B2 true AU2015220749B2 (en) 2020-12-24

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AU2015220749A Active AU2015220749B2 (en) 2014-02-21 2015-02-20 Single-stranded oligonucleotide probes for chromosome or gene copy enumeration

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US (3) US10752955B2 (enExample)
EP (1) EP3108006B1 (enExample)
JP (2) JP6982392B2 (enExample)
AU (1) AU2015220749B2 (enExample)
CA (1) CA2940111C (enExample)
DK (1) DK3108006T3 (enExample)
ES (1) ES2689568T3 (enExample)
WO (1) WO2015124702A1 (enExample)

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AU2015326827B2 (en) * 2014-10-02 2019-11-07 Ventana Medical Systems, Inc. Polymers and conjugates comprising the same
JP7038209B2 (ja) 2017-11-13 2022-03-17 エフ．ホフマン－ラ ロシュ アーゲー エピタコ電気泳動を使用する試料分析のための装置
EP3864403A1 (en) 2018-10-12 2021-08-18 F. Hoffmann-La Roche AG Detection methods for epitachophoresis workflow automation
WO2020229437A1 (en) 2019-05-14 2020-11-19 F. Hoffmann-La Roche Ag Devices and methods for sample analysis
CN111411146B (zh) * 2020-03-31 2024-01-16 宜昌美光硅谷生命科技股份有限公司 一种检测和定量单拷贝染色体外dna或rna的方法
CN112795649A (zh) * 2021-01-05 2021-05-14 武汉友芝友医疗科技股份有限公司 一种用于检测her2基因扩增水平的探针组及其应用
CN114214318A (zh) * 2021-11-30 2022-03-22 广州康立明生物科技股份有限公司 一种染色体着丝粒探针
WO2024215528A1 (en) 2023-04-13 2024-10-17 Ventana Medical Systems, Inc. Proliferation assay for fixed solid tumors
WO2025193604A1 (en) 2024-03-11 2025-09-18 Ventana Medical Systems, Inc. Non-enzymatic dissociation of ffpe tissue and generation of single cells with intact cell surface markers

Citations (1)

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Publication number Priority date Publication date Assignee Title
WO2001057277A2 (en) * 2000-02-04 2001-08-09 Aeomica, Inc. Human genome-derived single exon nucleic acid probes useful for analysis of gene expression in human fetal liver

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US5447841A (en) 1986-01-16 1995-09-05 The Regents Of The Univ. Of California Methods for chromosome-specific staining
JPH0686697A (ja) * 1991-04-09 1994-03-29 Univ California 反復配列染色体特異的核酸プローブ
US5750340A (en) * 1995-04-07 1998-05-12 University Of New Mexico In situ hybridization solution and process
US6046004A (en) * 1997-02-27 2000-04-04 Lorne Park Research, Inc. Solution hybridization of nucleic acids with antisense probes having modified backbones
US6573043B1 (en) * 1998-10-07 2003-06-03 Genentech, Inc. Tissue analysis and kits therefor
US20030017491A1 (en) 2000-09-14 2003-01-23 Zuo-Rong Shi Chromogenic in situ hybridization methods, kits, and compositions
JP2002296279A (ja) * 2001-03-29 2002-10-09 Hitachi Software Eng Co Ltd バイオチップ及びプローブ設計方法
US20020160401A1 (en) 2001-03-29 2002-10-31 Yasuyuki Nozaki Biochip and method of designing probes
EP1989329A2 (en) * 2006-01-25 2008-11-12 Board of Regents, The University of Texas System Detection and diagnosis of smoking related cancers
US7807356B2 (en) 2006-03-09 2010-10-05 Agilent Technologies, Inc. Labeled nucleotide composition
JP5126644B2 (ja) * 2006-05-31 2013-01-23 独立行政法人産業技術総合研究所 遺伝子発現プロファイルを用いた漢方薬の評価法
US20080299555A1 (en) * 2007-05-30 2008-12-04 Hiroaki Nitta Multicolor chromogenic detection of biomarkers
EP2335221B8 (en) * 2008-09-16 2016-05-25 Novartis AG Reproducible quantification of biomarker expression
ES2645754T3 (es) 2009-07-30 2017-12-07 F. Hoffmann-La Roche Ag Conjunto de sondas de oligonucleótidos así como métodos y usos relacionados con el mismo
EP2627780B1 (en) * 2010-10-12 2018-02-21 Universite Libre De Bruxelles Bach2 repression in cells
CA2838736A1 (en) * 2011-06-07 2012-12-13 Caris Mpi, Inc. Molecular profiling for cancer
US10510435B2 (en) * 2013-04-30 2019-12-17 California Institute Of Technology Error correction of multiplex imaging analysis by sequential hybridization

Patent Citations (1)

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Publication number Priority date Publication date Assignee Title
WO2001057277A2 (en) * 2000-02-04 2001-08-09 Aeomica, Inc. Human genome-derived single exon nucleic acid probes useful for analysis of gene expression in human fetal liver

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
WANG G P ET AL, "HIV integration site selection: Analysis by massively parallel pyrosequencing reveals association with epigenetic modifications", GENOME RESEARCH, vol. 17, no. 8, pages 1186 - 1194, (2007-06-01) *

Also Published As

Publication number Publication date
US11788149B2 (en) 2023-10-17
JP2020089374A (ja) 2020-06-11
AU2015220749A1 (en) 2016-07-07
CA2940111C (en) 2022-03-15
CA2940111A1 (en) 2015-08-27
ES2689568T3 (es) 2018-11-14
DK3108006T3 (en) 2018-10-15
US20170009305A1 (en) 2017-01-12
EP3108006B1 (en) 2018-08-01
JP6982392B2 (ja) 2021-12-17
US10752955B2 (en) 2020-08-25
JP2017511698A (ja) 2017-04-27
US20240084395A1 (en) 2024-03-14
EP3108006A1 (en) 2016-12-28
WO2015124702A1 (en) 2015-08-27
US20210002726A1 (en) 2021-01-07

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