JP2017511129A5 - - Google Patents
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- JP2017511129A5 JP2017511129A5 JP2016559160A JP2016559160A JP2017511129A5 JP 2017511129 A5 JP2017511129 A5 JP 2017511129A5 JP 2016559160 A JP2016559160 A JP 2016559160A JP 2016559160 A JP2016559160 A JP 2016559160A JP 2017511129 A5 JP2017511129 A5 JP 2017511129A5
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- JP
- Japan
- Prior art keywords
- amino acid
- seq
- residue
- polypeptide
- acid sequence
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Ceased
Links
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201461972182P | 2014-03-28 | 2014-03-28 | |
| US61/972,182 | 2014-03-28 | ||
| PCT/US2015/023087 WO2015148974A2 (en) | 2014-03-28 | 2015-03-27 | Engineered light-activated anion channel proteins and methods of use thereof |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2017511129A JP2017511129A (ja) | 2017-04-20 |
| JP2017511129A5 true JP2017511129A5 (enExample) | 2018-05-10 |
Family
ID=54196574
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2016559160A Ceased JP2017511129A (ja) | 2014-03-28 | 2015-03-27 | 遺伝子操作された光活性化アニオンチャネルタンパク質及びその使用方法 |
Country Status (8)
| Country | Link |
|---|---|
| US (3) | US10052383B2 (enExample) |
| EP (2) | EP3122761B1 (enExample) |
| JP (1) | JP2017511129A (enExample) |
| CN (1) | CN106459138A (enExample) |
| AU (1) | AU2015237265A1 (enExample) |
| CA (1) | CA2943367A1 (enExample) |
| ES (1) | ES2725951T3 (enExample) |
| WO (1) | WO2015148974A2 (enExample) |
Families Citing this family (26)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US9274099B2 (en) | 2005-07-22 | 2016-03-01 | The Board Of Trustees Of The Leland Stanford Junior University | Screening test drugs to identify their effects on cell membrane voltage-gated ion channel |
| US8906360B2 (en) | 2005-07-22 | 2014-12-09 | The Board Of Trustees Of The Leland Stanford Junior University | Light-activated cation channel and uses thereof |
| US8926959B2 (en) | 2005-07-22 | 2015-01-06 | The Board Of Trustees Of The Leland Stanford Junior University | System for optical stimulation of target cells |
| WO2008086470A1 (en) | 2007-01-10 | 2008-07-17 | The Board Of Trustees Of The Leland Stanford Junior University | System for optical stimulation of target cells |
| WO2008106694A2 (en) | 2007-03-01 | 2008-09-04 | The Board Of Trustees Of The Leland Stanford Junior University | Systems, methods and compositions for optical stimulation of target cells |
| US10434327B2 (en) | 2007-10-31 | 2019-10-08 | The Board Of Trustees Of The Leland Stanford Junior University | Implantable optical stimulators |
| MY169771A (en) | 2008-04-23 | 2019-05-15 | Univ Leland Stanford Junior | Systems, methods and compositions for optical stimulation of target cells |
| BRPI0915583A2 (pt) | 2008-06-17 | 2016-01-26 | Univ Leland Stanford Junior | aparelho e métodos para controle do desenvolvimento celular |
| US9101759B2 (en) | 2008-07-08 | 2015-08-11 | The Board Of Trustees Of The Leland Stanford Junior University | Materials and approaches for optical stimulation of the peripheral nervous system |
| CA2816971A1 (en) | 2010-11-05 | 2012-05-10 | The Board Of Trustees Of The Leland Stanford Junior University | Light-activated chimeric opsins and methods of using the same |
| CN103491770B (zh) | 2010-11-05 | 2016-06-08 | 斯坦福大学托管董事会 | 稳定阶跃函数视蛋白及其使用方法 |
| US8696722B2 (en) | 2010-11-22 | 2014-04-15 | The Board Of Trustees Of The Leland Stanford Junior University | Optogenetic magnetic resonance imaging |
| EP3524676A1 (en) | 2011-12-16 | 2019-08-14 | The Board of Trustees of The Leland Stanford Junior University | Opsin polypeptides and methods of use thereof |
| EP2817068B1 (en) | 2012-02-21 | 2017-04-12 | The Board of Trustees of the Leland Stanford Junior University | Compositions for treating neurogenic disorders of the pelvic floor |
| WO2016209654A1 (en) | 2015-06-22 | 2016-12-29 | The Board Of Trustees Of The Leland Stanford Junior University | Methods and devices for imaging and/or optogenetic control of light-responsive neurons |
| US11684284B2 (en) | 2015-07-21 | 2023-06-27 | The Board Of Trustees Of The Leland Stanford Junior University | Carbon fiber optrodes for magnetic resonance imaging compatible optogenetics |
| WO2017048808A1 (en) * | 2015-09-15 | 2017-03-23 | The Board Of Trustees Of The Leland Stanford Junior University | Light-responsive polypeptides and methods of use thereof |
| AU2017293925C1 (en) | 2016-07-07 | 2025-02-27 | Howard Hughes Medical Institute | Modified ligand-gated ion channels and methods of use |
| US11294165B2 (en) | 2017-03-30 | 2022-04-05 | The Board Of Trustees Of The Leland Stanford Junior University | Modular, electro-optical device for increasing the imaging field of view using time-sequential capture |
| KR20260035215A (ko) * | 2017-11-10 | 2026-03-12 | 하워드 휴즈 메디컬 인스티튜트 | 변형된 리간드-게이팅 이온 채널 및 사용 방법 |
| CN108192896B (zh) * | 2018-02-10 | 2021-05-07 | 中国烟草总公司郑州烟草研究院 | 一个烟草慢阴离子通道蛋白NtSLAH1及其应用 |
| WO2020061079A1 (en) * | 2018-09-18 | 2020-03-26 | California Institute Of Technology | Engineered light-sensitive proteins |
| US12325729B2 (en) | 2018-09-20 | 2025-06-10 | National University Corporation, Iwate University | Modified channel rhodopsin |
| CN111263086A (zh) * | 2020-02-10 | 2020-06-09 | 江南大学 | 细胞融合的光电传感器的制作方法及其成像系统的工作方法 |
| US11921271B2 (en) | 2020-05-22 | 2024-03-05 | The Board Of Trustees Of The Leland Stanford Junior Univeristy | Multifocal macroscope for large field of view imaging of dynamic specimens |
| WO2025189030A1 (en) | 2024-03-07 | 2025-09-12 | Stellaromics, Inc. | Methods and systems for volumetric imaging |
Family Cites Families (50)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4797368A (en) | 1985-03-15 | 1989-01-10 | The United States Of America As Represented By The Department Of Health And Human Services | Adeno-associated virus as eukaryotic expression vector |
| US5139941A (en) | 1985-10-31 | 1992-08-18 | University Of Florida Research Foundation, Inc. | AAV transduction vectors |
| AU7906691A (en) | 1990-05-23 | 1991-12-10 | United States of America, as represented by the Secretary, U.S. Department of Commerce, The | Adeno-associated virus (aav)-based eucaryotic vectors |
| WO1991019810A1 (en) | 1990-06-15 | 1991-12-26 | California Biotechnology Inc. | Transgenic non-human mammal displaying the amyloid-forming pathology of alzheimer's disease |
| US5173414A (en) | 1990-10-30 | 1992-12-22 | Applied Immune Sciences, Inc. | Production of recombinant adeno-associated virus vectors |
| US5252479A (en) | 1991-11-08 | 1993-10-12 | Research Corporation Technologies, Inc. | Safe vector for gene therapy |
| US5985930A (en) | 1996-11-21 | 1999-11-16 | Pasinetti; Giulio M. | Treatment of neurodegenerative conditions with nimesulide |
| DK1944362T3 (en) | 1997-09-05 | 2016-01-25 | Genzyme Corp | Fremgangsmåder til fremstilling af hjælpevirusfri præparater med høj titer af rekombinante AAV-vektorer |
| US6566118B1 (en) | 1997-09-05 | 2003-05-20 | Targeted Genetics Corporation | Methods for generating high titer helper-free preparations of released recombinant AAV vectors |
| US6989264B2 (en) | 1997-09-05 | 2006-01-24 | Targeted Genetics Corporation | Methods for generating high titer helper-free preparations of released recombinant AAV vectors |
| US6080849A (en) | 1997-09-10 | 2000-06-27 | Vion Pharmaceuticals, Inc. | Genetically modified tumor-targeted bacteria with reduced virulence |
| EP2369002A1 (en) | 1999-08-09 | 2011-09-28 | Targeted Genetics Corporation | Enhancement of expression of a single-stranded, heterologous nucleotide sequence from recombinant viral vectors by designing the sequence such that it forms intrastrand base pairs |
| US7632679B2 (en) | 2002-07-16 | 2009-12-15 | The Trustees Of Columbia University In The City Of New York | Systems and methods for screening for modulators of neural differentiation |
| US8906360B2 (en) | 2005-07-22 | 2014-12-09 | The Board Of Trustees Of The Leland Stanford Junior University | Light-activated cation channel and uses thereof |
| US9274099B2 (en) | 2005-07-22 | 2016-03-01 | The Board Of Trustees Of The Leland Stanford Junior University | Screening test drugs to identify their effects on cell membrane voltage-gated ion channel |
| US8926959B2 (en) | 2005-07-22 | 2015-01-06 | The Board Of Trustees Of The Leland Stanford Junior University | System for optical stimulation of target cells |
| US10052497B2 (en) | 2005-07-22 | 2018-08-21 | The Board Of Trustees Of The Leland Stanford Junior University | System for optical stimulation of target cells |
| US9238150B2 (en) | 2005-07-22 | 2016-01-19 | The Board Of Trustees Of The Leland Stanford Junior University | Optical tissue interface method and apparatus for stimulating cells |
| EP2061891B1 (en) | 2006-08-24 | 2012-04-11 | Virovek, Inc. | Expression in insect cells of genes with overlapping open reading frames, methods and compositions therefor |
| WO2008086470A1 (en) | 2007-01-10 | 2008-07-17 | The Board Of Trustees Of The Leland Stanford Junior University | System for optical stimulation of target cells |
| WO2008101128A1 (en) | 2007-02-14 | 2008-08-21 | The Board Of Trustees Of The Leland Stanford Junior University | System, method and applications involving identification of biological circuits such as neurological characteristics |
| WO2008106694A2 (en) | 2007-03-01 | 2008-09-04 | The Board Of Trustees Of The Leland Stanford Junior University | Systems, methods and compositions for optical stimulation of target cells |
| US8545543B2 (en) | 2009-10-08 | 2013-10-01 | Massachusetts Institute Of Technology | Methods and apparatus for microstructure lightguides |
| US10035027B2 (en) | 2007-10-31 | 2018-07-31 | The Board Of Trustees Of The Leland Stanford Junior University | Device and method for ultrasonic neuromodulation via stereotactic frame based technique |
| US10434327B2 (en) | 2007-10-31 | 2019-10-08 | The Board Of Trustees Of The Leland Stanford Junior University | Implantable optical stimulators |
| JP5544659B2 (ja) | 2008-03-24 | 2014-07-09 | 国立大学法人東北大学 | 改変された光受容体チャネル型ロドプシンタンパク質 |
| MY169771A (en) | 2008-04-23 | 2019-05-15 | Univ Leland Stanford Junior | Systems, methods and compositions for optical stimulation of target cells |
| AU2009256457B2 (en) | 2008-05-29 | 2014-06-26 | The Board Of Trustees Of The Leland Stanford Junior University | Cell line, system and method for optical control of secondary messengers |
| CA2728238C (en) | 2008-06-17 | 2019-03-12 | M. Bret Schneider | Methods, systems and devices for optical stimulation of target cells using an optical transmission element |
| BRPI0915583A2 (pt) | 2008-06-17 | 2016-01-26 | Univ Leland Stanford Junior | aparelho e métodos para controle do desenvolvimento celular |
| US9101759B2 (en) | 2008-07-08 | 2015-08-11 | The Board Of Trustees Of The Leland Stanford Junior University | Materials and approaches for optical stimulation of the peripheral nervous system |
| NZ602416A (en) | 2008-11-14 | 2014-08-29 | Univ Leland Stanford Junior | Optically-based stimulation of target cells and modifications thereto |
| CA2791094A1 (en) | 2010-03-17 | 2011-09-22 | The Board Of Trustees Of The Leland Stanford Junior University | Light-sensitive ion-passing molecules |
| WO2012061741A2 (en) | 2010-11-05 | 2012-05-10 | The Board Of Trustees Of The Leland Stanford Junior University. | Control and characterization of psychotic states |
| CN103491770B (zh) | 2010-11-05 | 2016-06-08 | 斯坦福大学托管董事会 | 稳定阶跃函数视蛋白及其使用方法 |
| WO2012061690A2 (en) | 2010-11-05 | 2012-05-10 | The Board Of Trustees Of The Leland Stanford Junior University | Optically-controlled cns dysfunction |
| CN106376525A (zh) | 2010-11-05 | 2017-02-08 | 斯坦福大学托管董事会 | 记忆功能的控制和表征 |
| EP2635341B1 (en) | 2010-11-05 | 2018-08-08 | The Board of Trustees of the Leland Stanford Junior University | Upconversion of light for use in optogenetic methods |
| EP3225108A1 (en) | 2010-11-05 | 2017-10-04 | The Board of Trustees of The Leland Stanford Junior University | Optogenetic control of reward-related behaviors |
| CA2816971A1 (en) * | 2010-11-05 | 2012-05-10 | The Board Of Trustees Of The Leland Stanford Junior University | Light-activated chimeric opsins and methods of using the same |
| US8957028B2 (en) | 2010-11-13 | 2015-02-17 | Massachusetts Institute Of Technology | Red-shifted opsin molecules and uses thereof |
| US8696722B2 (en) | 2010-11-22 | 2014-04-15 | The Board Of Trustees Of The Leland Stanford Junior University | Optogenetic magnetic resonance imaging |
| EP3524676A1 (en) | 2011-12-16 | 2019-08-14 | The Board of Trustees of The Leland Stanford Junior University | Opsin polypeptides and methods of use thereof |
| EP2817068B1 (en) | 2012-02-21 | 2017-04-12 | The Board of Trustees of the Leland Stanford Junior University | Compositions for treating neurogenic disorders of the pelvic floor |
| AU2013235517B2 (en) | 2012-03-20 | 2018-11-08 | The Board Of Trustees Of The Leland Stanford Junior University | Non-human animal models of depression and methods of use thereof |
| EP3659518A1 (en) | 2012-11-21 | 2020-06-03 | Circuit Therapeutics, Inc. | System and method for optogenetic therapy |
| US9636380B2 (en) | 2013-03-15 | 2017-05-02 | The Board Of Trustees Of The Leland Stanford Junior University | Optogenetic control of inputs to the ventral tegmental area |
| CA2906756A1 (en) | 2013-03-15 | 2014-09-18 | The Board Of Trustees Of The Leland Stanford Junior University | Optogenetic control of behavioral state |
| JP6549559B2 (ja) | 2013-04-29 | 2019-07-24 | ザ ボード オブ トラスティーズ オブ ザ レランド スタンフォード ジュニア ユニバーシティー | 標的細胞における活動電位の光遺伝学的調節のための装置、システム及び方法 |
| CN105829538A (zh) | 2013-08-14 | 2016-08-03 | 小利兰·斯坦福大学托管委员会 | 用于控制疼痛的组合物和方法 |
-
2015
- 2015-03-27 EP EP15770114.5A patent/EP3122761B1/en not_active Not-in-force
- 2015-03-27 JP JP2016559160A patent/JP2017511129A/ja not_active Ceased
- 2015-03-27 CN CN201580028022.1A patent/CN106459138A/zh active Pending
- 2015-03-27 CA CA2943367A patent/CA2943367A1/en not_active Abandoned
- 2015-03-27 EP EP19156461.6A patent/EP3581580A1/en not_active Withdrawn
- 2015-03-27 ES ES15770114T patent/ES2725951T3/es active Active
- 2015-03-27 AU AU2015237265A patent/AU2015237265A1/en not_active Abandoned
- 2015-03-27 WO PCT/US2015/023087 patent/WO2015148974A2/en not_active Ceased
- 2015-03-27 US US15/126,859 patent/US10052383B2/en active Active
-
2018
- 2018-08-07 US US16/057,639 patent/US10478499B2/en active Active
-
2019
- 2019-10-11 US US16/600,076 patent/US20200030446A1/en not_active Abandoned
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