JP2017511129A5 - - Google Patents
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- JP2017511129A5 JP2017511129A5 JP2016559160A JP2016559160A JP2017511129A5 JP 2017511129 A5 JP2017511129 A5 JP 2017511129A5 JP 2016559160 A JP2016559160 A JP 2016559160A JP 2016559160 A JP2016559160 A JP 2016559160A JP 2017511129 A5 JP2017511129 A5 JP 2017511129A5
- Authority
- JP
- Japan
- Prior art keywords
- amino acid
- seq
- residue
- polypeptide
- acid sequence
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Ceased
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Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201461972182P | 2014-03-28 | 2014-03-28 | |
| US61/972,182 | 2014-03-28 | ||
| PCT/US2015/023087 WO2015148974A2 (en) | 2014-03-28 | 2015-03-27 | Engineered light-activated anion channel proteins and methods of use thereof |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2017511129A JP2017511129A (ja) | 2017-04-20 |
| JP2017511129A5 true JP2017511129A5 (enExample) | 2018-05-10 |
Family
ID=54196574
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2016559160A Ceased JP2017511129A (ja) | 2014-03-28 | 2015-03-27 | 遺伝子操作された光活性化アニオンチャネルタンパク質及びその使用方法 |
Country Status (8)
| Country | Link |
|---|---|
| US (3) | US10052383B2 (enExample) |
| EP (2) | EP3581580A1 (enExample) |
| JP (1) | JP2017511129A (enExample) |
| CN (1) | CN106459138A (enExample) |
| AU (1) | AU2015237265A1 (enExample) |
| CA (1) | CA2943367A1 (enExample) |
| ES (1) | ES2725951T3 (enExample) |
| WO (1) | WO2015148974A2 (enExample) |
Families Citing this family (27)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US8926959B2 (en) | 2005-07-22 | 2015-01-06 | The Board Of Trustees Of The Leland Stanford Junior University | System for optical stimulation of target cells |
| JP2009502140A (ja) | 2005-07-22 | 2009-01-29 | ザ ボード オブ トラスティーズ オブ ザ レランド スタンフォード ジュニア ユニバーシティー | 光活性化陽イオンチャネルおよびその使用 |
| US9274099B2 (en) | 2005-07-22 | 2016-03-01 | The Board Of Trustees Of The Leland Stanford Junior University | Screening test drugs to identify their effects on cell membrane voltage-gated ion channel |
| US20090093403A1 (en) | 2007-03-01 | 2009-04-09 | Feng Zhang | Systems, methods and compositions for optical stimulation of target cells |
| US8398692B2 (en) | 2007-01-10 | 2013-03-19 | The Board Of Trustees Of The Leland Stanford Junior University | System for optical stimulation of target cells |
| US10434327B2 (en) | 2007-10-31 | 2019-10-08 | The Board Of Trustees Of The Leland Stanford Junior University | Implantable optical stimulators |
| ES2701349T3 (es) | 2008-04-23 | 2019-02-21 | Univ Leland Stanford Junior | Sistemas, métodos y composiciones para la estimulación óptica de células diana |
| EP2303405A4 (en) | 2008-06-17 | 2017-12-27 | The Board of Trustees of the Leland Stanford Junior University | Apparatus and methods for controlling cellular development |
| WO2010006049A1 (en) | 2008-07-08 | 2010-01-14 | The Board Of Trustees Of The Leland Stanford Junior University | Materials and approaches for optical stimulation of the peripheral nervous system |
| EP3486253A1 (en) | 2010-11-05 | 2019-05-22 | The Board of Trustees of The Leland Stanford Junior University | Light-activated chimeric opsins and methods of using the same |
| US10568307B2 (en) | 2010-11-05 | 2020-02-25 | The Board Of Trustees Of The Leland Stanford Junior University | Stabilized step function opsin proteins and methods of using the same |
| US8696722B2 (en) | 2010-11-22 | 2014-04-15 | The Board Of Trustees Of The Leland Stanford Junior University | Optogenetic magnetic resonance imaging |
| CA2859364C (en) | 2011-12-16 | 2019-05-07 | The Board Of Trustees Of The Leland Stanford Junior University | Opsin polypeptides and methods of use thereof |
| ES2628006T3 (es) | 2012-02-21 | 2017-08-01 | Circuit Therapeutics, Inc. | Composiciones para el tratamiento de trastornos neurogénicos del suelo pélvico |
| US10568516B2 (en) | 2015-06-22 | 2020-02-25 | The Board Of Trustees Of The Leland Stanford Junior University | Methods and devices for imaging and/or optogenetic control of light-responsive neurons |
| EP3324833B1 (en) | 2015-07-21 | 2021-03-17 | The Board of Trustees of the Leland Stanford Junior University | Carbon fiber optrodes for magnetic resonance imaging compatible optogenetics |
| US11801301B2 (en) | 2015-09-15 | 2023-10-31 | The Board Of Trustees Of The Leland Stanford Junior University | Light-responsive polypeptides and methods of use thereof |
| IL311984A (en) | 2016-07-07 | 2024-06-01 | Hughes Howard Med Inst | Modified ligand-gated ion channels and methods of use |
| US11294165B2 (en) | 2017-03-30 | 2022-04-05 | The Board Of Trustees Of The Leland Stanford Junior University | Modular, electro-optical device for increasing the imaging field of view using time-sequential capture |
| CN111556751B (zh) * | 2017-11-10 | 2024-07-12 | 霍华休斯医学研究院 | 经修饰的配体门控的离子通道及使用方法 |
| CN108192896B (zh) * | 2018-02-10 | 2021-05-07 | 中国烟草总公司郑州烟草研究院 | 一个烟草慢阴离子通道蛋白NtSLAH1及其应用 |
| US11858969B2 (en) | 2018-09-18 | 2024-01-02 | California Institute Of Technology | Engineered light-sensitive proteins |
| EP3854876A4 (en) * | 2018-09-20 | 2022-11-30 | National University Corporation, Iwate University | MODIFIED CHANNEL RRHODOPSIN |
| CN111263086A (zh) * | 2020-02-10 | 2020-06-09 | 江南大学 | 细胞融合的光电传感器的制作方法及其成像系统的工作方法 |
| US11921271B2 (en) | 2020-05-22 | 2024-03-05 | The Board Of Trustees Of The Leland Stanford Junior Univeristy | Multifocal macroscope for large field of view imaging of dynamic specimens |
| EP4334471A1 (en) | 2021-05-07 | 2024-03-13 | The Broad Institute Inc. | Spatiotemporally resolved transcriptomics at subcellular resolution |
| WO2025189030A1 (en) | 2024-03-07 | 2025-09-12 | Stellaromics, Inc. | Methods and systems for volumetric imaging |
Family Cites Families (50)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4797368A (en) | 1985-03-15 | 1989-01-10 | The United States Of America As Represented By The Department Of Health And Human Services | Adeno-associated virus as eukaryotic expression vector |
| US5139941A (en) | 1985-10-31 | 1992-08-18 | University Of Florida Research Foundation, Inc. | AAV transduction vectors |
| AU7906691A (en) | 1990-05-23 | 1991-12-10 | United States of America, as represented by the Secretary, U.S. Department of Commerce, The | Adeno-associated virus (aav)-based eucaryotic vectors |
| JPH06507782A (ja) | 1990-06-15 | 1994-09-08 | サイオス ノバ インコーポレイテッド | アルツハイマー病のアミロイド形成開症状を示すヒト以外の組換え哺乳動物 |
| US5173414A (en) | 1990-10-30 | 1992-12-22 | Applied Immune Sciences, Inc. | Production of recombinant adeno-associated virus vectors |
| US5252479A (en) | 1991-11-08 | 1993-10-12 | Research Corporation Technologies, Inc. | Safe vector for gene therapy |
| US5985930A (en) | 1996-11-21 | 1999-11-16 | Pasinetti; Giulio M. | Treatment of neurodegenerative conditions with nimesulide |
| US6995006B2 (en) | 1997-09-05 | 2006-02-07 | Targeted Genetics Corporation | Methods for generating high titer helper-free preparations of released recombinant AAV vectors |
| CA2995542A1 (en) | 1997-09-05 | 1999-03-11 | Genzyme Corporation | Methods for generating high titer helper-free preparations of recombinant aav vectors |
| US6566118B1 (en) | 1997-09-05 | 2003-05-20 | Targeted Genetics Corporation | Methods for generating high titer helper-free preparations of released recombinant AAV vectors |
| US6080849A (en) | 1997-09-10 | 2000-06-27 | Vion Pharmaceuticals, Inc. | Genetically modified tumor-targeted bacteria with reduced virulence |
| US6596535B1 (en) | 1999-08-09 | 2003-07-22 | Targeted Genetics Corporation | Metabolically activated recombinant viral vectors and methods for the preparation and use |
| US7632679B2 (en) | 2002-07-16 | 2009-12-15 | The Trustees Of Columbia University In The City Of New York | Systems and methods for screening for modulators of neural differentiation |
| US9274099B2 (en) | 2005-07-22 | 2016-03-01 | The Board Of Trustees Of The Leland Stanford Junior University | Screening test drugs to identify their effects on cell membrane voltage-gated ion channel |
| JP2009502140A (ja) | 2005-07-22 | 2009-01-29 | ザ ボード オブ トラスティーズ オブ ザ レランド スタンフォード ジュニア ユニバーシティー | 光活性化陽イオンチャネルおよびその使用 |
| US10052497B2 (en) | 2005-07-22 | 2018-08-21 | The Board Of Trustees Of The Leland Stanford Junior University | System for optical stimulation of target cells |
| US20090093403A1 (en) | 2007-03-01 | 2009-04-09 | Feng Zhang | Systems, methods and compositions for optical stimulation of target cells |
| US8926959B2 (en) | 2005-07-22 | 2015-01-06 | The Board Of Trustees Of The Leland Stanford Junior University | System for optical stimulation of target cells |
| US9238150B2 (en) | 2005-07-22 | 2016-01-19 | The Board Of Trustees Of The Leland Stanford Junior University | Optical tissue interface method and apparatus for stimulating cells |
| ES2385679T3 (es) | 2006-08-24 | 2012-07-30 | Virovek, Inc. | Expresión de células de insecto de genes con marcos de lectura abiertos superpuestos, métodos y composiciones de éstos |
| US8398692B2 (en) | 2007-01-10 | 2013-03-19 | The Board Of Trustees Of The Leland Stanford Junior University | System for optical stimulation of target cells |
| US8401609B2 (en) | 2007-02-14 | 2013-03-19 | The Board Of Trustees Of The Leland Stanford Junior University | System, method and applications involving identification of biological circuits such as neurological characteristics |
| US8545543B2 (en) | 2009-10-08 | 2013-10-01 | Massachusetts Institute Of Technology | Methods and apparatus for microstructure lightguides |
| US10035027B2 (en) | 2007-10-31 | 2018-07-31 | The Board Of Trustees Of The Leland Stanford Junior University | Device and method for ultrasonic neuromodulation via stereotactic frame based technique |
| US10434327B2 (en) | 2007-10-31 | 2019-10-08 | The Board Of Trustees Of The Leland Stanford Junior University | Implantable optical stimulators |
| WO2009119782A1 (ja) | 2008-03-24 | 2009-10-01 | 国立大学法人東北大学 | 改変された光受容体チャネル型ロドプシンタンパク質 |
| ES2701349T3 (es) | 2008-04-23 | 2019-02-21 | Univ Leland Stanford Junior | Sistemas, métodos y composiciones para la estimulación óptica de células diana |
| EP2294208B1 (en) | 2008-05-29 | 2013-05-08 | The Board of Trustees of The Leland Stanford Junior University | Cell line, system and method for optical control of secondary messengers |
| EP2303405A4 (en) | 2008-06-17 | 2017-12-27 | The Board of Trustees of the Leland Stanford Junior University | Apparatus and methods for controlling cellular development |
| JP2011525130A (ja) | 2008-06-17 | 2011-09-15 | ボード オブ トラスティーズ オブ ザ レランド スタンフォード ジュニア ユニバーシティ | 光伝送素子を用いた標的細胞の光刺激のための方法、システム、および装置 |
| WO2010006049A1 (en) | 2008-07-08 | 2010-01-14 | The Board Of Trustees Of The Leland Stanford Junior University | Materials and approaches for optical stimulation of the peripheral nervous system |
| NZ602416A (en) | 2008-11-14 | 2014-08-29 | Univ Leland Stanford Junior | Optically-based stimulation of target cells and modifications thereto |
| EP3399024A1 (en) | 2010-03-17 | 2018-11-07 | The Board of Trustees of The Leland Stanford Junior University | Light-sensitive ion-passing molecules |
| EP3486253A1 (en) | 2010-11-05 | 2019-05-22 | The Board of Trustees of The Leland Stanford Junior University | Light-activated chimeric opsins and methods of using the same |
| US10568307B2 (en) | 2010-11-05 | 2020-02-25 | The Board Of Trustees Of The Leland Stanford Junior University | Stabilized step function opsin proteins and methods of using the same |
| CN106422081B (zh) | 2010-11-05 | 2019-06-21 | 斯坦福大学托管董事会 | 用于光遗传学方法的光的上转换 |
| US10086012B2 (en) | 2010-11-05 | 2018-10-02 | The Board Of Trustees Of The Leland Stanford Junior University | Control and characterization of memory function |
| JP5986575B2 (ja) | 2010-11-05 | 2016-09-06 | ザ ボード オブ トラスティーズ オブ ザ レランド スタンフォード ジュニア ユニバーシティー | 精神病状態の制御および特徴付け |
| ES2625179T3 (es) | 2010-11-05 | 2017-07-18 | The Board Of Trustees Of The Leland Stanford Junior University | Control optogenético de comportamientos relacionados con la recompensa |
| CN103384469B (zh) | 2010-11-05 | 2016-06-15 | 斯坦福大学托管董事会 | 光控cns功能障碍 |
| US8957028B2 (en) | 2010-11-13 | 2015-02-17 | Massachusetts Institute Of Technology | Red-shifted opsin molecules and uses thereof |
| US8696722B2 (en) | 2010-11-22 | 2014-04-15 | The Board Of Trustees Of The Leland Stanford Junior University | Optogenetic magnetic resonance imaging |
| CA2859364C (en) | 2011-12-16 | 2019-05-07 | The Board Of Trustees Of The Leland Stanford Junior University | Opsin polypeptides and methods of use thereof |
| ES2628006T3 (es) | 2012-02-21 | 2017-08-01 | Circuit Therapeutics, Inc. | Composiciones para el tratamiento de trastornos neurogénicos del suelo pélvico |
| JP6396883B2 (ja) | 2012-03-20 | 2018-09-26 | ザ ボード オブ トラスティーズ オブ ザ レランド スタンフォード ジュニア ユニバーシティー | うつ病の非ヒト動物モデルおよびその使用方法 |
| CA2894718A1 (en) | 2012-11-21 | 2014-05-30 | Circuit Therapeutics, Inc. | System and method for optogenetic therapy |
| US9636380B2 (en) | 2013-03-15 | 2017-05-02 | The Board Of Trustees Of The Leland Stanford Junior University | Optogenetic control of inputs to the ventral tegmental area |
| ES2742492T3 (es) | 2013-03-15 | 2020-02-14 | Univ Leland Stanford Junior | Control optogenético del estado conductual |
| US10220092B2 (en) | 2013-04-29 | 2019-03-05 | The Board Of Trustees Of The Leland Stanford Junior University | Devices, systems and methods for optogenetic modulation of action potentials in target cells |
| JP6621747B2 (ja) | 2013-08-14 | 2019-12-18 | ザ ボード オブ トラスティーズ オブ ザ レランド スタンフォード ジュニア ユニバーシティー | 疼痛を制御するための組成物及び方法 |
-
2015
- 2015-03-27 EP EP19156461.6A patent/EP3581580A1/en not_active Withdrawn
- 2015-03-27 ES ES15770114T patent/ES2725951T3/es active Active
- 2015-03-27 CN CN201580028022.1A patent/CN106459138A/zh active Pending
- 2015-03-27 EP EP15770114.5A patent/EP3122761B1/en not_active Not-in-force
- 2015-03-27 JP JP2016559160A patent/JP2017511129A/ja not_active Ceased
- 2015-03-27 AU AU2015237265A patent/AU2015237265A1/en not_active Abandoned
- 2015-03-27 US US15/126,859 patent/US10052383B2/en active Active
- 2015-03-27 WO PCT/US2015/023087 patent/WO2015148974A2/en not_active Ceased
- 2015-03-27 CA CA2943367A patent/CA2943367A1/en not_active Abandoned
-
2018
- 2018-08-07 US US16/057,639 patent/US10478499B2/en active Active
-
2019
- 2019-10-11 US US16/600,076 patent/US20200030446A1/en not_active Abandoned
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