JP2017500017A5 - - Google Patents
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- JP2017500017A5 JP2017500017A5 JP2016532136A JP2016532136A JP2017500017A5 JP 2017500017 A5 JP2017500017 A5 JP 2017500017A5 JP 2016532136 A JP2016532136 A JP 2016532136A JP 2016532136 A JP2016532136 A JP 2016532136A JP 2017500017 A5 JP2017500017 A5 JP 2017500017A5
- Authority
- JP
- Japan
- Prior art keywords
- culture
- cells
- liters
- item
- viable
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Withdrawn
Links
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201361919629P | 2013-12-20 | 2013-12-20 | |
| US61/919,629 | 2013-12-20 | ||
| PCT/US2014/071701 WO2015095809A1 (en) | 2013-12-20 | 2014-12-19 | Use of perfusion seed cultures to improve biopharmaceutical fed-batch production capacity and product quality |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2020000268A Division JP2020054388A (ja) | 2013-12-20 | 2020-01-06 | 生物薬剤フェドバッチ生産能力及び生産物品質を改善するための灌流シード培養の使用 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2017500017A JP2017500017A (ja) | 2017-01-05 |
| JP2017500017A5 true JP2017500017A5 (https=) | 2018-02-08 |
Family
ID=52347449
Family Applications (3)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2016532136A Withdrawn JP2017500017A (ja) | 2013-12-20 | 2014-12-19 | 生物薬剤フェドバッチ生産能力及び生産物品質を改善するための灌流シード培養の使用 |
| JP2020000268A Withdrawn JP2020054388A (ja) | 2013-12-20 | 2020-01-06 | 生物薬剤フェドバッチ生産能力及び生産物品質を改善するための灌流シード培養の使用 |
| JP2022197095A Pending JP2023022317A (ja) | 2013-12-20 | 2022-12-09 | 生物薬剤フェドバッチ生産能力及び生産物品質を改善するための灌流シード培養の使用 |
Family Applications After (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2020000268A Withdrawn JP2020054388A (ja) | 2013-12-20 | 2020-01-06 | 生物薬剤フェドバッチ生産能力及び生産物品質を改善するための灌流シード培養の使用 |
| JP2022197095A Pending JP2023022317A (ja) | 2013-12-20 | 2022-12-09 | 生物薬剤フェドバッチ生産能力及び生産物品質を改善するための灌流シード培養の使用 |
Country Status (5)
| Country | Link |
|---|---|
| US (2) | US20160289633A1 (https=) |
| EP (1) | EP3083933B1 (https=) |
| JP (3) | JP2017500017A (https=) |
| DK (1) | DK3083933T3 (https=) |
| WO (1) | WO2015095809A1 (https=) |
Families Citing this family (28)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DK3083933T3 (da) | 2013-12-20 | 2026-03-16 | Biogen Ma Inc | Anvendelse af perfusionssåningskulturer til forbedring af biofarmaceutisk fed-batch-produktionskapacitet og -produktkvalitet |
| TW202204596A (zh) | 2014-06-06 | 2022-02-01 | 美商健臻公司 | 灌注培養方法及其用途 |
| TWI776235B (zh) | 2014-06-09 | 2022-09-01 | 美商健臻公司 | 種子罐培養法(seed train processes)及其用途 |
| US20180312802A1 (en) * | 2015-11-02 | 2018-11-01 | Ares Trading S.A. | Methods for modulating production profiles of recombinant proteins in perfusion mode |
| CN116083344A (zh) | 2016-01-26 | 2023-05-09 | 勃林格殷格翰国际公司 | 对连续流动搅拌釜反应器细胞培养系统的连接灌注 |
| WO2018044699A1 (en) | 2016-08-27 | 2018-03-08 | 3D Biotek, Llc | Bioreactor |
| EP3681989A1 (en) * | 2017-09-15 | 2020-07-22 | Bristol-Myers Squibb Company | Online biomass capacitance monitoring during large scale production of polypeptides of interest |
| WO2019071076A1 (en) | 2017-10-06 | 2019-04-11 | Lonza Ltd. | AUTOMATED CONTROL OF CELL CULTURE BY SPECTROSCOPY RAMAN |
| IL315801A (en) | 2017-10-16 | 2024-11-01 | Regeneron Pharma | Perfusion bioreactor and methods of using it |
| KR20200083564A (ko) * | 2017-11-13 | 2020-07-08 | 암젠 인크 | 단백질 산물을 제조하는 방법 |
| KR20250111232A (ko) * | 2017-12-11 | 2025-07-22 | 암젠 인크 | 이중특이적 항체 생성물의 연속 제조 공정 |
| CN110241012B (zh) * | 2018-03-09 | 2022-11-01 | 嘉和生物药业有限公司 | 一种生物大分子上游分阶段截留的生产方法、生产模块及在生产中的应用 |
| WO2019212921A1 (en) * | 2018-04-29 | 2019-11-07 | Regenxbio Inc. | Scalable clarification process for recombinant aav production |
| US12071607B2 (en) * | 2018-06-01 | 2024-08-27 | Lonza Ltd. | Midscale model for organic growth and phasing |
| EP3818078B1 (en) * | 2018-07-03 | 2024-02-28 | Bristol-Myers Squibb Company | Methods of producing recombinant proteins |
| WO2020086408A1 (en) | 2018-10-26 | 2020-04-30 | The United States Of America, As Represented By The Secretary, Department Of Health And Human Services | A high-yield perfusion-based transient gene expression bioprocess |
| EP3875595A4 (en) * | 2018-11-02 | 2022-07-13 | Kyowa Kirin Co., Ltd. | Liquid medium preparation method |
| US20220098556A1 (en) * | 2019-01-25 | 2022-03-31 | Biogen Ma Inc. | Seed culture process for aav production |
| WO2020208050A1 (en) * | 2019-04-11 | 2020-10-15 | Merck Patent Gmbh | Cell culture media comprising keto acids |
| CA3144125A1 (en) * | 2019-07-16 | 2021-01-21 | Haihong Sun | Cell culture method based on high-density and continuous inoculation and use thereof |
| JP2022543781A (ja) * | 2019-08-01 | 2022-10-14 | ブリストル－マイヤーズ スクイブ カンパニー | フェッドバッチ細胞培養におけるタンパク質産生性の改良方法 |
| US12529024B2 (en) | 2019-11-15 | 2026-01-20 | Lonza Ltd | Process and system for producing an inoculum |
| CA3201327A1 (en) * | 2020-12-08 | 2022-06-16 | Partner Therapeutics, Inc. | Manufacture of granulocyte macrophage-colony stimulating factor |
| BR112023017717A2 (pt) | 2021-05-03 | 2024-01-09 | Boehringer Ingelheim Int | Método para produção de espesolimabe |
| WO2023114901A2 (en) | 2021-12-15 | 2023-06-22 | Oxford Biomedica Solutions Llc | Methods and compositions for the production of adeno-associated virus |
| CN119137263A (zh) * | 2022-03-07 | 2024-12-13 | 奥特吉尼克斯制药公司 | 改进的分批aav产生系统和方法 |
| CN120153061A (zh) * | 2022-09-06 | 2025-06-13 | 美国安进公司 | 精简灌注细胞培养方法 |
| WO2026033566A2 (en) | 2024-08-09 | 2026-02-12 | Omnibrx Biotechnologies Private Limited | A multistage bioreactor system and method thereof |
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| EP1400536A1 (en) | 1991-06-14 | 2004-03-24 | Genentech Inc. | Method for making humanized antibodies |
| DE4122599C2 (de) | 1991-07-08 | 1993-11-11 | Deutsches Krebsforsch | Phagemid zum Screenen von Antikörpern |
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| US5667988A (en) | 1992-01-27 | 1997-09-16 | The Scripps Research Institute | Methods for producing antibody libraries using universal or randomized immunoglobulin light chains |
| US5856179A (en) | 1994-03-10 | 1999-01-05 | Genentech, Inc. | Polypeptide production in animal cell culture |
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| CA2557046A1 (en) * | 2004-03-05 | 2005-10-13 | John Crowley | Process for cell culturing by continuous perfusion and alternating tangential flow |
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| TWI456062B (zh) * | 2006-09-13 | 2014-10-11 | Abbvie Inc | 細胞培養改良 |
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| RU2010147652A (ru) * | 2008-04-23 | 2012-05-27 | Симфоген А/С (Dk) | Способы производства поликлонального белка |
| UA106047C2 (uk) * | 2008-06-13 | 2014-07-25 | Сентокор Орто Байотек Інк. | Спосіб отримання високої щільності життєздатних клітин в культурі клітин ссавців |
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| SG10201505217WA (en) | 2010-07-09 | 2015-08-28 | Biogen Hemophilia Inc | Chimeric clotting factors |
| UA126265C2 (uk) | 2010-07-09 | 2022-09-14 | Байовератів Терапьютікс Інк. | Поліпептид фактора іх і спосіб його застосування |
| EP2591101B1 (en) | 2010-07-09 | 2018-11-07 | Bioverativ Therapeutics Inc. | Systems for factor viii processing and methods thereof |
| CN103415610B (zh) | 2011-03-18 | 2016-10-19 | 通用电气健康护理生物科学股份公司 | 用于培养细胞的弹性袋 |
| DK2726600T3 (en) * | 2011-07-01 | 2017-05-15 | Amgen Inc | Mammalian Cell Culture |
| DK3083933T3 (da) | 2013-12-20 | 2026-03-16 | Biogen Ma Inc | Anvendelse af perfusionssåningskulturer til forbedring af biofarmaceutisk fed-batch-produktionskapacitet og -produktkvalitet |
-
2014
- 2014-12-19 DK DK14827357.6T patent/DK3083933T3/da active
- 2014-12-19 JP JP2016532136A patent/JP2017500017A/ja not_active Withdrawn
- 2014-12-19 US US15/038,698 patent/US20160289633A1/en not_active Abandoned
- 2014-12-19 WO PCT/US2014/071701 patent/WO2015095809A1/en not_active Ceased
- 2014-12-19 EP EP14827357.6A patent/EP3083933B1/en active Active
-
2020
- 2020-01-06 JP JP2020000268A patent/JP2020054388A/ja not_active Withdrawn
-
2022
- 2022-12-09 JP JP2022197095A patent/JP2023022317A/ja active Pending
-
2025
- 2025-01-17 US US19/027,281 patent/US20250382568A1/en active Pending
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