JP2017181518A5 - - Google Patents
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- JP2017181518A5 JP2017181518A5 JP2017111070A JP2017111070A JP2017181518A5 JP 2017181518 A5 JP2017181518 A5 JP 2017181518A5 JP 2017111070 A JP2017111070 A JP 2017111070A JP 2017111070 A JP2017111070 A JP 2017111070A JP 2017181518 A5 JP2017181518 A5 JP 2017181518A5
- Authority
- JP
- Japan
- Prior art keywords
- biomarker
- detection reagent
- autoantibody against
- tau
- seq
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
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Links
- 238000000034 method Methods 0.000 claims 20
- 239000000090 biomarker Substances 0.000 claims 12
- 239000003153 chemical reaction reagent Substances 0.000 claims 12
- 238000001514 detection method Methods 0.000 claims 12
- 239000012472 biological sample Substances 0.000 claims 6
- 150000001413 amino acids Chemical class 0.000 claims 5
- 238000003776 cleavage reaction Methods 0.000 claims 4
- 239000007857 degradation product Substances 0.000 claims 4
- 230000007017 scission Effects 0.000 claims 4
- 102000013498 tau Proteins Human genes 0.000 claims 4
- 108010026424 tau Proteins Proteins 0.000 claims 4
- 101000891579 Homo sapiens Microtubule-associated protein tau Proteins 0.000 claims 3
- 101100480719 Rattus norvegicus Mapt gene Proteins 0.000 claims 3
- 208000030886 Traumatic Brain injury Diseases 0.000 claims 3
- 125000003275 alpha amino acid group Chemical group 0.000 claims 3
- 102000057063 human MAPT Human genes 0.000 claims 3
- 230000000926 neurological effect Effects 0.000 claims 3
- 230000009529 traumatic brain injury Effects 0.000 claims 3
- 208000004051 Chronic Traumatic Encephalopathy Diseases 0.000 claims 2
- 210000004369 blood Anatomy 0.000 claims 2
- 239000008280 blood Substances 0.000 claims 2
- 210000001175 cerebrospinal fluid Anatomy 0.000 claims 2
- 208000017004 dementia pugilistica Diseases 0.000 claims 2
- 210000002381 plasma Anatomy 0.000 claims 2
- 210000003296 saliva Anatomy 0.000 claims 2
- 210000002966 serum Anatomy 0.000 claims 2
- 210000001519 tissue Anatomy 0.000 claims 2
- 210000002700 urine Anatomy 0.000 claims 2
- 208000024827 Alzheimer disease Diseases 0.000 claims 1
- 208000018737 Parkinson disease Diseases 0.000 claims 1
- 208000006011 Stroke Diseases 0.000 claims 1
- 208000027418 Wounds and injury Diseases 0.000 claims 1
- 230000006378 damage Effects 0.000 claims 1
- 208000014674 injury Diseases 0.000 claims 1
- 230000004770 neurodegeneration Effects 0.000 claims 1
- 208000015122 neurodegenerative disease Diseases 0.000 claims 1
Applications Claiming Priority (8)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US24212309P | 2009-09-14 | 2009-09-14 | |
| US61/242,123 | 2009-09-14 | ||
| US35450410P | 2010-06-14 | 2010-06-14 | |
| US61/354,504 | 2010-06-14 | ||
| US35577910P | 2010-06-17 | 2010-06-17 | |
| US61/355,779 | 2010-06-17 | ||
| US38015810P | 2010-09-03 | 2010-09-03 | |
| US61/380,158 | 2010-09-03 |
Related Parent Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2015253708A Division JP2016105097A (ja) | 2009-09-14 | 2015-12-25 | ニューロン損傷診断のためのマイクロrna、自己抗体およびタンパク質マーカー |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2017181518A JP2017181518A (ja) | 2017-10-05 |
| JP2017181518A5 true JP2017181518A5 (OSRAM) | 2017-11-30 |
| JP6469760B2 JP6469760B2 (ja) | 2019-02-13 |
Family
ID=43733138
Family Applications (3)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2012528991A Active JP5909447B2 (ja) | 2009-09-14 | 2010-09-14 | ニューロン損傷診断のためのマイクロrna、自己抗体およびタンパク質マーカー |
| JP2015253708A Pending JP2016105097A (ja) | 2009-09-14 | 2015-12-25 | ニューロン損傷診断のためのマイクロrna、自己抗体およびタンパク質マーカー |
| JP2017111070A Active JP6469760B2 (ja) | 2009-09-14 | 2017-06-05 | ニューロン損傷診断のためのマイクロrna、自己抗体およびタンパク質マーカー |
Family Applications Before (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2012528991A Active JP5909447B2 (ja) | 2009-09-14 | 2010-09-14 | ニューロン損傷診断のためのマイクロrna、自己抗体およびタンパク質マーカー |
| JP2015253708A Pending JP2016105097A (ja) | 2009-09-14 | 2015-12-25 | ニューロン損傷診断のためのマイクロrna、自己抗体およびタンパク質マーカー |
Country Status (8)
| Country | Link |
|---|---|
| US (3) | US20130022982A1 (OSRAM) |
| EP (1) | EP2478360B1 (OSRAM) |
| JP (3) | JP5909447B2 (OSRAM) |
| AU (2) | AU2010291933B2 (OSRAM) |
| CA (1) | CA2774173A1 (OSRAM) |
| ES (1) | ES2687469T3 (OSRAM) |
| HU (1) | HUE040281T2 (OSRAM) |
| WO (1) | WO2011032155A2 (OSRAM) |
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| AU2009212463A1 (en) * | 2008-02-04 | 2009-08-13 | Banyan Biomarkers, Inc. | Process to diagnose or treat brain injury |
| EP2143735A1 (en) | 2008-07-10 | 2010-01-13 | Institut Pasteur | Variable domains of camelid heavy-chain antibodies directed against glial fibrillary acidic proteins |
| US20140342381A1 (en) | 2008-08-11 | 2014-11-20 | Banyan Biomarkers, Inc. | Devices and methods for biomarker detection process and assay of neurological condition |
| AU2009282117B2 (en) * | 2008-08-11 | 2016-05-12 | Banyan Biomarkers, Inc. | Biomarker detection process and assay of neurological condition |
| US20120094295A1 (en) | 2008-11-21 | 2012-04-19 | The Johns Hopkins University | Neurodegenerative disease diagnostic compositions and methods of use |
| US20170315136A9 (en) | 2009-06-19 | 2017-11-02 | Banyan Biomarkers, Inc. | Biomarker assay of neurological condition |
| CA2766057A1 (en) * | 2009-06-19 | 2010-12-23 | Banyan Biomarkers, Inc. | Biomarker assay of neurological condition |
| US20120202231A1 (en) | 2009-07-18 | 2012-08-09 | Kevin Ka-Wang Wang | Synergistic biomarker assay of neurological condition using s-100b |
| JP5909447B2 (ja) | 2009-09-14 | 2016-04-26 | バンヤン・バイオマーカーズ・インコーポレーテッド | ニューロン損傷診断のためのマイクロrna、自己抗体およびタンパク質マーカー |
| JP2013524220A (ja) | 2010-04-01 | 2013-06-17 | バンヤン・バイオマーカーズ・インコーポレイテッド | 神経毒性を検出するためのマーカーおよびアッセイ |
| WO2011160096A2 (en) | 2010-06-17 | 2011-12-22 | Banyan Biomarkers, Inc. | Glial fibrillary acidic protein, autoantigens and autoantibodies thereto as biomarkers of neural injury or neurological disorder or condition |
| WO2013040502A2 (en) | 2011-09-14 | 2013-03-21 | The Henry M. Jackson Foundation For The Advancement Of Military Medicine, Inc. | Processes and kits to detect and monitor for diagnostic biomarkers for post traumatic stress disorder (ptsd) and to differentiate between suicidal and non-suicidal form of the disorder |
| US20140024053A1 (en) | 2012-07-20 | 2014-01-23 | Banyan Biomarkers, Inc. | Methods, kits and devices for detecting bii-spectrin, and breakdown products thereof, as biomarkers for the diagnosis of neural injury |
| US20140275294A1 (en) | 2013-03-15 | 2014-09-18 | Banyan Biomarkers, Inc. | Devices and methods for biomarker detection process and assay of liver injury |
| WO2014194329A1 (en) | 2013-05-31 | 2014-12-04 | Banyan Biomarkers, Inc. | NEURAL SPECIFIC S100β FOR BIOMARKER ASSAYS AND DEVICES FOR DETECTION OF A NEUROLOGICAL CONDITION |
-
2010
- 2010-09-14 JP JP2012528991A patent/JP5909447B2/ja active Active
- 2010-09-14 ES ES10816275T patent/ES2687469T3/es active Active
- 2010-09-14 CA CA2774173A patent/CA2774173A1/en not_active Abandoned
- 2010-09-14 AU AU2010291933A patent/AU2010291933B2/en not_active Expired - Fee Related
- 2010-09-14 WO PCT/US2010/048789 patent/WO2011032155A2/en not_active Ceased
- 2010-09-14 US US13/395,931 patent/US20130022982A1/en not_active Abandoned
- 2010-09-14 HU HUE10816275A patent/HUE040281T2/hu unknown
- 2010-09-14 EP EP10816275.1A patent/EP2478360B1/en not_active Revoked
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2015
- 2015-12-25 JP JP2015253708A patent/JP2016105097A/ja active Pending
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2016
- 2016-12-07 AU AU2016269481A patent/AU2016269481B2/en not_active Ceased
- 2016-12-27 US US15/391,755 patent/US10041959B2/en active Active
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2017
- 2017-06-05 JP JP2017111070A patent/JP6469760B2/ja active Active
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2018
- 2018-08-01 US US16/052,512 patent/US20190064188A1/en not_active Abandoned
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