JP2017014255A5 - - Google Patents

Download PDF

Info

Publication number
JP2017014255A5
JP2017014255A5 JP2016159414A JP2016159414A JP2017014255A5 JP 2017014255 A5 JP2017014255 A5 JP 2017014255A5 JP 2016159414 A JP2016159414 A JP 2016159414A JP 2016159414 A JP2016159414 A JP 2016159414A JP 2017014255 A5 JP2017014255 A5 JP 2017014255A5
Authority
JP
Japan
Prior art keywords
cancer
tumor
complex
nanoparticle core
pharmaceutical composition
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP2016159414A
Other languages
English (en)
Japanese (ja)
Other versions
JP2017014255A (ja
Filing date
Publication date
Application filed filed Critical
Publication of JP2017014255A publication Critical patent/JP2017014255A/ja
Publication of JP2017014255A5 publication Critical patent/JP2017014255A5/ja
Pending legal-status Critical Current

Links

JP2016159414A 2010-11-12 2016-08-16 癌の予防および治療のための組成物および方法 Pending JP2017014255A (ja)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US41333010P 2010-11-12 2010-11-12
US61/413,330 2010-11-12

Related Parent Applications (1)

Application Number Title Priority Date Filing Date
JP2013538208A Division JP5991979B2 (ja) 2010-11-12 2011-11-11 癌の予防および治療のための組成物および方法

Publications (2)

Publication Number Publication Date
JP2017014255A JP2017014255A (ja) 2017-01-19
JP2017014255A5 true JP2017014255A5 (cg-RX-API-DMAC10.html) 2017-06-08

Family

ID=44983530

Family Applications (2)

Application Number Title Priority Date Filing Date
JP2013538208A Expired - Fee Related JP5991979B2 (ja) 2010-11-12 2011-11-11 癌の予防および治療のための組成物および方法
JP2016159414A Pending JP2017014255A (ja) 2010-11-12 2016-08-16 癌の予防および治療のための組成物および方法

Family Applications Before (1)

Application Number Title Priority Date Filing Date
JP2013538208A Expired - Fee Related JP5991979B2 (ja) 2010-11-12 2011-11-11 癌の予防および治療のための組成物および方法

Country Status (14)

Country Link
US (3) US9511151B2 (cg-RX-API-DMAC10.html)
EP (1) EP2637700A2 (cg-RX-API-DMAC10.html)
JP (2) JP5991979B2 (cg-RX-API-DMAC10.html)
KR (1) KR20140037789A (cg-RX-API-DMAC10.html)
CN (2) CN105770906A (cg-RX-API-DMAC10.html)
AU (2) AU2011328077A1 (cg-RX-API-DMAC10.html)
BR (1) BR112013007064A2 (cg-RX-API-DMAC10.html)
CA (1) CA2817710C (cg-RX-API-DMAC10.html)
IL (1) IL225471B (cg-RX-API-DMAC10.html)
MX (1) MX350203B (cg-RX-API-DMAC10.html)
NZ (1) NZ608695A (cg-RX-API-DMAC10.html)
RU (2) RU2623038C2 (cg-RX-API-DMAC10.html)
SG (2) SG189909A1 (cg-RX-API-DMAC10.html)
WO (1) WO2012062904A2 (cg-RX-API-DMAC10.html)

Families Citing this family (39)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP5650406B2 (ja) * 2007-03-07 2015-01-07 ユーティーアイ リミテッド パートナーシップ 自己免疫状態の予防および治療のための組成物および方法
US20140105980A1 (en) * 2012-10-11 2014-04-17 Uti Limited Partnership Methods and compositions for treating multiple sclerosis and related disorders
BR112013007069A2 (pt) * 2010-09-29 2016-09-13 Uti Limited Partnership métodos para tratar doença autoimune usando nanoesferas biocompatíveis e bioabsorvíveis
US9511151B2 (en) 2010-11-12 2016-12-06 Uti Limited Partnership Compositions and methods for the prevention and treatment of cancer
US10988516B2 (en) 2012-03-26 2021-04-27 Uti Limited Partnership Methods and compositions for treating inflammation
US9156897B2 (en) * 2012-06-08 2015-10-13 Alkermes, Inc. Fusion polypeptides comprising an active protein linked to a mucin-domain polypeptide
EP2711418B1 (en) 2012-09-25 2017-08-23 Miltenyi Biotec GmbH Method for polyclonal stimulation of T cells by flexible nanomatrices
US10548957B2 (en) * 2012-09-28 2020-02-04 Dana-Farber Cancer Institute, Inc. Targeted expansion of Qa-1-peptide-specific regulatory CD8 T cells to ameliorate arthritis
US9603948B2 (en) 2012-10-11 2017-03-28 Uti Limited Partnership Methods and compositions for treating multiple sclerosis and related disorders
AU2014302784B2 (en) 2013-06-24 2020-01-23 Neximmune Compositions and methods for immunotherapy
ES2612918T3 (es) 2013-07-10 2017-05-19 Miltenyi Biotec Gmbh Método para inducir la proliferación de células asesinas naturales por nanomatrices móviles
SG10201803780UA (en) 2013-11-04 2018-06-28 Uti Lp Methods and compositions for sustained immunotherapy
TWI689310B (zh) 2014-07-11 2020-04-01 巨生生醫股份有限公司 治療鐵缺乏症之方法
CN106317202A (zh) * 2014-09-05 2017-01-11 马恒标 大蒜中提取得到的抗肿瘤活性的多肽
BR112017008042A2 (pt) 2014-10-20 2017-12-26 Juno Therapeutics Inc métodos e composições para dosagem em terapia de célula adotiva
JP6743022B2 (ja) 2014-12-24 2020-08-19 ネクシミューン インコーポレイテッド 免疫療法のためのナノ粒子組成物及び方法
ES3055030T3 (en) 2015-05-06 2026-02-09 Uti Lp Nanoparticle compositions for sustained therapy
KR102080107B1 (ko) * 2015-05-14 2020-02-21 더 보오드 오브 트러스티스 오브 더 유니버시티 오브 일리노이즈 순환되는 종양세포를 바이오마커로 사용하여 암 치료요법의 효율을 모니터링 하는 방법
AU2016270823B2 (en) 2015-06-01 2020-09-03 California Institute Of Technology Compositions and methods for screening T cells with antigens for specific populations
CN110191893B (zh) * 2016-11-22 2023-03-21 武汉华大吉诺因生物科技有限公司 多肽及其应用
MX2019010171A (es) 2017-02-27 2019-10-15 Juno Therapeutics Inc Composiciones, articulos de fabricacion y metodos relacionados con la dosificacion en la terapia celular.
EP3592862A1 (en) 2017-03-08 2020-01-15 California Institute of Technology Pairing antigen specificity of a t cell with t cell receptor sequences
SG11201909290TA (en) 2017-04-07 2019-11-28 Uti Lp Assay to measure the potency of receptor-ligand interactions in nanomedicines
IL327498A (en) 2017-06-02 2026-05-01 Juno Therapeutics Inc Articles of manufacture and methods for treatment using adoptive cell therapy
AU2018283319B2 (en) * 2017-06-16 2023-11-09 Mayo Foundation For Medical Education And Research Materials and methods for increasing immune responses
KR20200030593A (ko) * 2017-07-21 2020-03-20 버클리 라잇츠, 인크. 항원 제시 합성 표면, 공유결합으로 관능화된 표면, 활성화된 t 세포, 및 이들의 용도
WO2019089858A2 (en) 2017-11-01 2019-05-09 Juno Therapeutics, Inc. Methods of assessing or monitoring a response to a cell therapy
JP7357626B2 (ja) 2017-11-01 2023-10-06 ジュノー セラピューティクス インコーポレイテッド 操作された細胞の治療用組成物を生成するためのプロセス
EP3716949A4 (en) 2017-11-29 2022-05-18 UTI Limited Partnership METHODS OF TREATMENT OF AUTOIMMUNE DISEASES
BR112020011223A2 (pt) 2017-12-08 2020-11-17 Juno Therapeutics Inc marcadores fenotípicos para terapia celular e mé-todos relacionados
CN108359013A (zh) * 2018-02-07 2018-08-03 上海交通大学 一种人工抗原递呈纳米制剂及其用于体内外扩增特异性t细胞的应用
KR20210063362A (ko) * 2018-09-21 2021-06-01 버클리 라잇츠, 인크. 작용화된 웰 플레이트, 이의 제조 및 사용 방법
AU2020277486A1 (en) * 2019-05-23 2022-01-27 Uti Limited Partnership Nanoparticles comprising non-classical MHC and uses thereof
US20220249389A1 (en) 2019-07-12 2022-08-11 Oregon Health & Science University Immunotherapeutic constructs and methods of their use
MX2019015508A (es) 2019-12-18 2021-06-21 Univ Guadalajara Nanopartículas para el tratamiento del cáncer.
WO2022204267A1 (en) 2021-03-24 2022-09-29 Alkermes, Inc. Upar antibodies and fusion proteins with the same
CN113403276A (zh) * 2021-06-23 2021-09-17 河北大学 抗体功能化的外泌体制剂及其制备方法和应用
WO2024130393A1 (en) * 2022-12-21 2024-06-27 Moskovchenko Svitlana Nanoparticle and method of synthesis thereof
WO2025217590A1 (en) * 2024-04-11 2025-10-16 Envoya, Inc. Compositions and methods of making polymeric nanoparticles for delivery of therapeutic agents

Family Cites Families (147)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US1000470A (en) 1908-02-11 1911-08-15 Frank C Widmann Ring-mold.
US1017295A (en) 1910-08-20 1912-02-13 Adolph F Hensler Journal-box.
US1048588A (en) 1911-05-05 1912-12-31 Adams & Westlake Co Pole-changer.
US1008080A (en) 1911-07-15 1911-11-07 Jacub Schwartzman Bed-spring.
US1012404A (en) 1911-07-29 1911-12-19 Frederick L S Means Protective caster.
US1044155A (en) 1912-04-11 1912-11-12 Diamond Match Co Splint-drying means for match-machines.
US4367110A (en) 1979-07-02 1983-01-04 Toppan Printing Co. Decorative laminate and a manufacturing method therefor
US4452901A (en) 1980-03-20 1984-06-05 Ciba-Geigy Corporation Electrophoretically transferring electropherograms to nitrocellulose sheets for immuno-assays
US4554101A (en) 1981-01-09 1985-11-19 New York Blood Center, Inc. Identification and preparation of epitopes on antigens and allergens on the basis of hydrophilicity
FR2504010B1 (fr) 1981-04-15 1985-10-25 Sanofi Sa Medicaments anticancereux contenant la chaine a de la ricine associee a un anticorps antimelanome et procede pour leur preparation
GB2097032B (en) 1981-04-22 1984-09-19 Teron International Urban Dev A combined ceiling air and services distribution system mechanical chasse and structural roof member
US4478946A (en) 1981-07-02 1984-10-23 South African Inventions Development Corporation Carrier bound immunosorbent
US4671958A (en) 1982-03-09 1987-06-09 Cytogen Corporation Antibody conjugates for the delivery of compounds to target sites
DE3377484D1 (en) 1982-04-19 1988-09-01 Nissan Motor Method for controlling reduction ratio of continuously variable transmission with acceleration compensation
US4818542A (en) 1983-11-14 1989-04-04 The University Of Kentucky Research Foundation Porous microspheres for drug delivery and methods for making same
US4542225A (en) 1984-08-29 1985-09-17 Dana-Farber Cancer Institute, Inc. Acid-cleavable compound
US4659839A (en) 1984-10-10 1987-04-21 Mallinckrodt, Inc. Coupling agents for radiolabeled antibody fragments
ATE66469T1 (de) 1985-01-14 1991-09-15 Neorx Corp Metall-radionuklid markiertes protein fuer diagnose und therapie.
US5171582A (en) 1985-07-31 1992-12-15 Ghent William R Treatment of iodine deficiency diseases
US4680338A (en) 1985-10-17 1987-07-14 Immunomedics, Inc. Bifunctional linker
US4699784A (en) 1986-02-25 1987-10-13 Center For Molecular Medicine & Immunology Tumoricidal methotrexate-antibody conjugate
US5258499A (en) 1988-05-16 1993-11-02 Vestar, Inc. Liposome targeting using receptor specific ligands
US5260422A (en) 1988-06-23 1993-11-09 Anergen, Inc. MHC conjugates useful in ameliorating autoimmunity
US6106840A (en) 1988-06-23 2000-08-22 Anergen, Inc. MHC conjugates useful in ameliorating autoimmunity
US4859839A (en) 1988-07-08 1989-08-22 Counter Computer Corporation Point-of-sale terminal for laundry or dry cleaning establishments
US5543390A (en) 1990-11-01 1996-08-06 State Of Oregon, Acting By And Through The Oregon State Board Of Higher Education, Acting For And On Behalf Of The Oregon Health Sciences University Covalent microparticle-drug conjugates for biological targeting
DE69232875T2 (de) 1991-04-23 2003-08-21 Anergen, Inc. MHC-Konjugate zur Verbesserung der Autoimmunität.
US5200189A (en) 1991-07-23 1993-04-06 Ecolab Inc. Peroxyacid antimicrobial composition
WO1993016725A1 (en) 1992-02-27 1993-09-02 The Board Of Trustees Of The Leland Stanford Junior University Early antigen for autoimmune diabetes
JP2631436B2 (ja) 1992-07-24 1997-07-16 徳厚 小島 排水立て管継手
US5972336A (en) 1992-11-03 1999-10-26 Oravax Merieux Co. Urease-based vaccine against helicobacter infection
CN1148812A (zh) 1994-03-28 1997-04-30 尼科梅德成像有限公司 “脂质体”
US6103379A (en) 1994-10-06 2000-08-15 Bar-Ilan University Process for the preparation of microspheres and microspheres made thereby
WO1996018105A1 (en) 1994-12-06 1996-06-13 The President And Fellows Of Harvard College Single chain t-cell receptor
DE19508058A1 (de) 1995-02-21 1996-08-22 Schering Ag Verfahren zur Herstellung von DTPA-Tetraestern der terminalen Carbonsäuren und deren Verwendung zur Herstellung pharmazeutischer Mittel
US5731168A (en) 1995-03-01 1998-03-24 Genentech, Inc. Method for making heteromultimeric polypeptides
US5840839A (en) 1996-02-09 1998-11-24 The United States Of America As Represented By The Secretary Of The Department Of Health And Human Services Alternative open reading frame DNA of a normal gene and a novel human cancer antigen encoded therein
US6033864A (en) 1996-04-12 2000-03-07 The Regents Of The University Of California Diagnosis, prevention and treatment of ulcerative colitis, and clinical subtypes thereof, using microbial UC pANCA antigens
DK0935607T3 (da) 1996-08-16 2004-12-06 Harvard College Oplöselige monovalente og multivalente MHC klasse II-fusionsproteiner samt anvendelser deraf
US20050003431A1 (en) 1996-08-16 2005-01-06 Wucherpfennig Kai W. Monovalent, multivalent, and multimeric MHC binding domain fusion proteins and conjugates, and uses therefor
AU741130B2 (en) 1997-09-16 2001-11-22 Oregon Health Sciences University Recombinant MHC molecules useful for manipulation of antigen-specific T-cells
BR9908082A (pt) 1998-02-19 2000-10-31 Harvard College Proteìna de fusão do complexo de histocompatibilidade principal classe ii, conjugado dos domìnios de ligação do complexo de histocompatibilidade principal multimérico, processos para detectar células t tendo uma especificidade do complexo definido de mhc / peptìdeo, para conferir a um indivìduo imunidade adotiva a um complexo definido de mhc / peptìdeo, para estimular ou ativar as células t reativas a um complexo definido de mhc / peptìdeo, para seletivamente matar células t reativas a um complexo definido de mhc / peptìdeo, para tolerizar um indivìduo humano a um complexo definido de mhc / peptìdeo, e, ácido nucleico isolado
EP1094828A4 (en) 1998-05-07 2005-01-26 Univ California USE OF TARGETED, NEGLIGATED TISSUE ANTIGENS TO MODULATE IMMUNE REACTIONS
DE19825371A1 (de) 1998-06-06 1999-12-09 Bayer Ag Elektrochrome Anzeigevorrichtung mit isolierten Zuleitungen
IL125608A0 (en) 1998-07-30 1999-03-12 Yeda Res & Dev Tumor associated antigen peptides and use of same as anti-tumor vaccines
US7807377B2 (en) * 1998-10-20 2010-10-05 Salvatore Albani Method of isolating antigen-specific T cells employing artificial antigen presenting cells
US6150022A (en) 1998-12-07 2000-11-21 Flex Products, Inc. Bright metal flake based pigments
JP2000213425A (ja) 1999-01-20 2000-08-02 Hino Motors Ltd Egrク―ラ
US7090973B1 (en) 1999-04-09 2006-08-15 Oscient Pharmaceuticals Corporation Nucleic acid sequences relating to Bacteroides fragilis for diagnostics and therapeutics
AU4825700A (en) 1999-05-06 2000-11-21 Genetics Institute Inc. Use of soluble costimulatory molecules to enhance immune responses
AU784551B2 (en) 1999-10-06 2006-05-04 Trustees Of The University Of Pennsylvania, The Cell targeting compositions and methods of using the same
US6585947B1 (en) 1999-10-22 2003-07-01 The Board Of Trustess Of The University Of Illinois Method for producing silicon nanoparticles
US6651655B1 (en) 2000-01-18 2003-11-25 Quadrant Technologies Limited Inhaled vaccines
US6797514B2 (en) 2000-02-24 2004-09-28 Xcyte Therapies, Inc. Simultaneous stimulation and concentration of cells
US7572631B2 (en) 2000-02-24 2009-08-11 Invitrogen Corporation Activation and expansion of T cells
KR100379250B1 (ko) 2000-12-04 2003-04-08 한국과학기술연구원 나노 단위 크기의 금속 입자가 함유된 고분자 복합 소재및 그 제조 방법
WO2002080963A1 (en) 2001-04-05 2002-10-17 Virginia Mason Research Center Methods of mhc class ii epitope mapping, detection of autoimmune t cells and antigens, and autoimmune treatment
DE10117858A1 (de) 2001-04-10 2002-10-24 Gsf Forschungszentrum Umwelt MHC-Tetramere
US20070129307A1 (en) 2001-06-22 2007-06-07 The University Of British Columbia Insulin epitopes for the treatment of type 1 diabetes
JP2004532896A (ja) 2001-06-22 2004-10-28 ザ ユニバーシティ オブ ブリティッシュ コロンビア I型糖尿病の診断及び治療
US20030124149A1 (en) 2001-07-06 2003-07-03 Shalaby Shalaby W. Bioactive absorbable microparticles as therapeutic vaccines
JP2005511761A (ja) 2001-07-10 2005-04-28 ノース・キャロライナ・ステイト・ユニヴァーシティ ナノ粒子送達ビヒクル
DE10144252A1 (de) 2001-08-31 2003-03-27 Fraunhofer Ges Forschung Nanopartikel mit daran immobilisiertem biologisch aktivem TNF
CA2466656C (en) 2001-11-09 2013-07-02 Nanosphere, Inc. Bioconjugate-nanoparticle probes
EP1581119B1 (en) 2001-12-17 2013-01-30 Corixa Corporation Compositions and methods for the therapy and diagnosis of inflammatory bowel disease
US6688494B2 (en) 2001-12-20 2004-02-10 Cima Nanotech, Inc. Process for the manufacture of metal nanoparticle
US7285289B2 (en) 2002-04-12 2007-10-23 Nagy Jon O Nanoparticle vaccines
US20040115216A1 (en) 2002-07-12 2004-06-17 The Johns Hopkins University Reagents and methods for engaging unique clonotypic lymphocyte receptors
DE10310261A1 (de) 2003-03-05 2004-09-23 Fraunhofer-Gesellschaft zur Förderung der angewandten Forschung e.V. Identifizierung von Antigen-Epitopen
US20040197304A1 (en) 2003-04-01 2004-10-07 The Procter & Gamble Company And Alimentary Health, Ltd. Methods of determining efficacy of treatments of inflammatory diseases of the bowel
US6929675B1 (en) 2003-04-24 2005-08-16 Sandia Corporation Synthesis metal nanoparticle
US20050118102A1 (en) 2003-04-28 2005-06-02 Intematix Corporation Spin resonance heating and/or imaging in medical applications
WO2004104185A1 (en) 2003-05-08 2004-12-02 Xcyte Therapies, Inc. Generation and isolation of antigen-specific t cells
US8758767B2 (en) 2003-05-20 2014-06-24 Albert Einstein College Of Medicine Of Yeshiva University Antigens targeted by prevalent pathogennic T cells in type 1 diabetes and uses thereof
US7060121B2 (en) 2003-06-25 2006-06-13 Hsing Kuang Lin Method of producing gold nanoparticle
WO2005007673A2 (en) 2003-07-03 2005-01-27 Rush University Medical Center Immunogenic peptides
US9149440B2 (en) 2003-09-02 2015-10-06 University Of South Florida Nanoparticles for drug-delivery
GB0321937D0 (en) 2003-09-19 2003-10-22 Univ Liverpool Nanoparticle conjugates and method of production thereof
CN1864020B (zh) 2003-10-09 2014-03-05 布鲁克斯仪器有限责任公司 阀组件
DE102004023187A1 (de) 2004-05-11 2005-12-01 Ganymed Pharmaceuticals Ag Identifizierung von Oberflächen-assoziierten Antigenen für die Tumordiagnose und -therapie
WO2006080951A2 (en) 2004-07-01 2006-08-03 Yale University Targeted and high density drug loaded polymeric materials
ES2625905T3 (es) 2004-10-01 2017-07-20 Midatech Ltd. Nanopartículas que comprenden antígenos y adyuvantes capaces de estimular linfocitos T cooperadores
WO2006054806A1 (ja) 2004-11-22 2006-05-26 Locomogene, Inc. クローン病関連自己抗原
US7462446B2 (en) 2005-03-18 2008-12-09 University Of Washington Magnetic nanoparticle compositions and methods
US20070059775A1 (en) 2005-03-29 2007-03-15 The Trustees Of Columbia University In The City Of New York Synthesis and conjugation of iron oxide nanoparticles to antibodies for targeting specific cells using fluorescence and MR imaging techniques
US7562421B2 (en) 2005-04-03 2009-07-21 Magen Eco Energy A.C.S. Ltd. Connecting clasp
US7326399B2 (en) 2005-04-15 2008-02-05 Headwaters Technology Innovation, Llc Titanium dioxide nanoparticles and nanoparticle suspensions and methods of making the same
WO2007024026A1 (ja) 2005-08-25 2007-03-01 Taiho Pharmaceutical Co., Ltd. T細胞認識エピトープペプチドを固定化又は内包化した生分解性ナノ粒子
US9393215B2 (en) 2005-12-02 2016-07-19 Novartis Ag Nanoparticles for use in immunogenic compositions
US20100061984A1 (en) 2006-01-20 2010-03-11 The Trustees Of The University Of Pennsylvania Compositions and methods for modulation of suppressor t cell activation
WO2008017517A1 (en) 2006-08-11 2008-02-14 Life Sciences Research Partners Vzw Immunogenic peptides and their use in immune disorders
US7816814B1 (en) 2006-08-18 2010-10-19 Hennessy Michael J Bi-directional power converters
CA2674632A1 (en) 2006-12-29 2008-07-10 University Of Washington Dual-functional nonfouling surfaces and materials
WO2008115641A2 (en) 2007-02-15 2008-09-25 Yale University Modular nanoparticles for adaptable vaccines
JP5650406B2 (ja) 2007-03-07 2015-01-07 ユーティーアイ リミテッド パートナーシップ 自己免疫状態の予防および治療のための組成物および方法
US20150250871A1 (en) 2007-03-07 2015-09-10 Uti Limited Partnership Methods and compositions for treating multiple sclerosis and related disorders
US20140105980A1 (en) 2012-10-11 2014-04-17 Uti Limited Partnership Methods and compositions for treating multiple sclerosis and related disorders
US20100151031A1 (en) 2007-03-23 2010-06-17 Desimone Joseph M Discrete size and shape specific organic nanoparticles designed to elicit an immune response
WO2009003493A2 (en) * 2007-07-03 2009-01-08 Dako Denmark A/S Mhc multimers, methods for their generation, labeling and use
US8666532B2 (en) 2007-07-22 2014-03-04 Camtek Ltd. Method and system for controlling a manufacturing process
JP5085240B2 (ja) 2007-09-03 2012-11-28 日本電波工業株式会社 水晶デバイス及び水晶デバイスの製造方法
JP5624471B2 (ja) 2007-09-24 2014-11-12 バーイラン ユニバーシティー 磁性金属酸化物で被覆されたポリマー性ナノ粒子及びその使用
WO2009064273A1 (en) 2007-11-16 2009-05-22 Paul Appelbaum Apparatus and method for packaging articles in clear plastic packages
WO2009078799A1 (en) 2007-12-17 2009-06-25 Marfl Ab New vaccine for the treatment of mycobacterium related disorders
US8629098B2 (en) 2008-01-15 2014-01-14 Yale University Compositions and methods for adoptive and active immunotherapy
CA2717719A1 (en) 2008-02-04 2009-08-13 David G. Fernig Nanoparticle conjugates
US20110151015A1 (en) 2008-03-04 2011-06-23 Liquikia Technologies, Inc. Immunomodulator particles and methods of treating
WO2009126835A2 (en) 2008-04-09 2009-10-15 University Of Washington Techtransfer Invention Licensing Magnetic nanoparticle and method for imaging t cells
US20090258355A1 (en) 2008-04-11 2009-10-15 Brookhaven Science Associates, Llc Nanoscale Clusters and Methods of Making Same
WO2010098788A2 (en) 2008-08-25 2010-09-02 Amplimmune, Inc. Pd-i antagonists and methods for treating infectious disease
US8323696B2 (en) 2008-08-29 2012-12-04 Ecole Polytechnique Federale De Lausanne Nanoparticles for immunotherapy
WO2010037397A1 (en) 2008-10-01 2010-04-08 Dako Denmark A/S Mhc multimers in cmv immune monitoring
WO2010037395A2 (en) 2008-10-01 2010-04-08 Dako Denmark A/S Mhc multimers in cancer vaccines and immune monitoring
US8343497B2 (en) 2008-10-12 2013-01-01 The Brigham And Women's Hospital, Inc. Targeting of antigen presenting cells with immunonanotherapeutics
CA2642141A1 (en) 2008-10-20 2010-04-20 Innovative Microelectronics Inc. Flange alignment pin
EP2353004B1 (en) 2008-11-12 2018-01-03 Yeda Research and Development Co. Ltd. Diagnosis of multiple sclerosis
WO2010080032A2 (en) 2009-01-09 2010-07-15 Stichting Het Nederlands Kanker Instituut Bead-assisted viral transduction
MX2011007559A (es) 2009-01-20 2011-12-06 Myelin Repair Foundation Inc Composiciones y metodos para induccion de tolerancia antigeno-especifica.
US8383085B2 (en) 2009-05-29 2013-02-26 University Of Manitoba Methods of making iron-containing nanoparticles
WO2011044186A1 (en) 2009-10-06 2011-04-14 The Board Of Trustees Of The University Of Illinois Human single-chain t cell receptors
GB0922066D0 (en) 2009-12-17 2010-02-03 Univ Belfast Modulator
GB201003088D0 (en) 2010-02-24 2010-04-14 Univ Exeter Method for the preparation of a novel nanoparticle conjugate
PL2598165T3 (pl) 2010-07-26 2018-02-28 Qu Biologics Inc. Immunogenne kompozycje przeciwzapalne
WO2012025936A2 (en) 2010-08-25 2012-03-01 Ramamohan Rao Davuluri Improved process for the preparation of rufinamide
WO2012031258A1 (en) 2010-09-03 2012-03-08 Oregon Health & Science University Recombinant t-cell receptor ligands with covalently bound peptides
BR112013007069A2 (pt) 2010-09-29 2016-09-13 Uti Limited Partnership métodos para tratar doença autoimune usando nanoesferas biocompatíveis e bioabsorvíveis
US9511151B2 (en) 2010-11-12 2016-12-06 Uti Limited Partnership Compositions and methods for the prevention and treatment of cancer
JP6077544B2 (ja) 2011-09-07 2017-02-08 ミダテック リミテッド ナノ粒子−ペプチド組成物
WO2013043662A1 (en) 2011-09-22 2013-03-28 Marv Enterprises Llc Method for the treatment of multiple sclerosis
EP2591801A1 (en) 2011-11-14 2013-05-15 Universitätsklinikum Hamburg-Eppendorf Nanoparticle compositions for generation of regulatory T cells and treatment of autoimmune diseases and other chronic inflammatory conditions
CN102376225B (zh) 2011-11-18 2013-09-04 深圳市华星光电技术有限公司 平板显示装置、立体显示装置以及等离子显示装置
US10758487B2 (en) 2011-12-09 2020-09-01 The Johns Hopkins University Artificial antigen presenting cells having a defined and dynamic shape
US10988516B2 (en) 2012-03-26 2021-04-27 Uti Limited Partnership Methods and compositions for treating inflammation
WO2013184976A2 (en) 2012-06-06 2013-12-12 Northwestern University Compositions and methods for antigen-specific tolerance
US9603948B2 (en) 2012-10-11 2017-03-28 Uti Limited Partnership Methods and compositions for treating multiple sclerosis and related disorders
JP6475167B2 (ja) 2012-12-21 2019-02-27 エフ.ホフマン−ラ ロシュ アーゲーF. Hoffmann−La Roche Aktiengesellschaft ジスルフィド結合した多価mhcクラスiを含む多機能タンパク質
US9335768B2 (en) 2013-09-12 2016-05-10 Lam Research Corporation Cluster mass flow devices and multi-line mass flow devices incorporating the same
SG10201803780UA (en) 2013-11-04 2018-06-28 Uti Lp Methods and compositions for sustained immunotherapy
EP3160453A1 (en) 2014-06-25 2017-05-03 Selecta Biosciences, Inc. Methods and compositions for treatment with synthetic nanocarriers and immune checkpoint inhibitors
JP6718450B2 (ja) 2014-12-19 2020-07-08 イーティーエッチ チューリッヒ キメラ抗原受容体及びその使用方法
EP3067366A1 (en) 2015-03-13 2016-09-14 Max-Delbrück-Centrum Für Molekulare Medizin Combined T cell receptor gene therapy of cancer against MHC I and MHC II-restricted epitopes of the tumor antigen NY-ESO-1
BR112017020750A2 (en) 2015-03-27 2018-06-26 President And Fellows Of Harvard College modified t-cells and methods of producing and using them
ES3055030T3 (en) 2015-05-06 2026-02-09 Uti Lp Nanoparticle compositions for sustained therapy
MA44907A (fr) 2015-09-11 2018-07-18 Agenus Inc Cellules hôtes génétiquement modifiées et leurs procédés d'utilisation
US20180127481A1 (en) 2016-11-09 2018-05-10 Uti Limited Partnership RECOMBINANT pMHC CLASS II MOLECULES
SG11201909290TA (en) 2017-04-07 2019-11-28 Uti Lp Assay to measure the potency of receptor-ligand interactions in nanomedicines
EP3716949A4 (en) 2017-11-29 2022-05-18 UTI Limited Partnership METHODS OF TREATMENT OF AUTOIMMUNE DISEASES

Similar Documents

Publication Publication Date Title
RU2017119820A (ru) Композиции и способы профилактики и лечения злокачественных новообразований
Ramakrishnan et al. Novel mechanism of synergistic effects of conventional chemotherapy and immune therapy of cancer
Ma et al. Increasing cure rates of solid tumors by immune checkpoint inhibitors
Musetti et al. Nanoparticle-mediated remodeling of the tumor microenvironment to enhance immunotherapy
Chen et al. Driving CARs on the uneven road of antigen heterogeneity in solid tumors
Schettini et al. Nab-paclitaxel for the treatment of triple-negative breast cancer: Rationale, clinical data and future perspectives
Fang et al. Nanoparticle‐based manipulation of antigen‐presenting cells for cancer immunotherapy
Houot et al. T-cell–based immunotherapy: adoptive cell transfer and checkpoint inhibition
Baxevanis et al. Combinatorial treatments including vaccines, chemotherapy and monoclonal antibodies for cancer therapy
JP2013543855A5 (cg-RX-API-DMAC10.html)
Curiel Immunotherapy: a useful strategy to help combat multidrug resistance
Sofias et al. A paradigm shift in cancer nanomedicine: From traditional tumor targeting to leveraging the immune system
Zhang et al. Combination of active specific immunotherapy or adoptive antibody or lymphocyte immunotherapy with chemotherapy in the treatment of cancer
Zhang et al. The synergistic strategies for the immuno‐oncotherapy with photothermal nanoagents
JP2018536655A5 (cg-RX-API-DMAC10.html)
Kamath Cancer vaccines: An unkept promise?
Saied et al. Immunotherapy for solid tumors—a review for surgeons
Lee et al. Engineered nanocarriers for targeted lung cancer therapy: Mechanistic innovations and recent clinical progress
Qiang et al. Immunotherapy for small cell lung cancer: the current state and future trajectories
Cytryn et al. Biomarker Analysis From a Phase II Study of AgenT-797 (invariant natural killer T cells) with Botensilimab (Fc-enhanced CTLA-4 inhibitor) and Balstilimab (anti-PD-1) in PD-1 Refractory Gastroesophageal Cancer
Singh et al. Cancer immunotherapy: Moving forward with peptide T-cell vaccines
Paul et al. Smart multifunctional nanosystem: Next-generation drug delivery platform for drug-resistant breast cancer
Sasada et al. A patient with stage IV gastric cancer who acquired complete remission after undergoing multi-peptide dendritic cell immunotherapy in combination with standard therapies
Rüttinger et al. Current immunotherapeutic strategies in lung cancer
Akbar et al. Inorganic nanoparticulate carriers in cancer vaccination