JP2016539949A5 - - Google Patents
Download PDFInfo
- Publication number
- JP2016539949A5 JP2016539949A5 JP2016535014A JP2016535014A JP2016539949A5 JP 2016539949 A5 JP2016539949 A5 JP 2016539949A5 JP 2016535014 A JP2016535014 A JP 2016535014A JP 2016535014 A JP2016535014 A JP 2016535014A JP 2016539949 A5 JP2016539949 A5 JP 2016539949A5
- Authority
- JP
- Japan
- Prior art keywords
- type
- adverse effects
- gastrointestinal tract
- symptoms
- trichothecene
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 229930013292 trichothecene Natural products 0.000 claims 28
- 238000000034 method Methods 0.000 claims 21
- 230000002411 adverse Effects 0.000 claims 18
- 230000000694 effects Effects 0.000 claims 18
- LZAJKCZTKKKZNT-PMNGPLLRSA-N trichothecene Chemical compound C12([C@@]3(CC[C@H]2OC2C=C(CCC23C)C)C)CO1 LZAJKCZTKKKZNT-PMNGPLLRSA-N 0.000 claims 17
- 231100000678 Mycotoxin Toxicity 0.000 claims 15
- 210000001035 gastrointestinal tract Anatomy 0.000 claims 15
- 239000002636 mycotoxin Substances 0.000 claims 15
- 239000003463 adsorbent Substances 0.000 claims 14
- 231100000572 poisoning Toxicity 0.000 claims 14
- 230000000607 poisoning effect Effects 0.000 claims 14
- 208000024891 symptom Diseases 0.000 claims 14
- 150000003327 trichothecene derivatives Chemical class 0.000 claims 11
- 229910000323 aluminium silicate Inorganic materials 0.000 claims 8
- HNPSIPDUKPIQMN-UHFFFAOYSA-N dioxosilane;oxo(oxoalumanyloxy)alumane Chemical compound O=[Si]=O.O=[Al]O[Al]=O HNPSIPDUKPIQMN-UHFFFAOYSA-N 0.000 claims 8
- 241001465754 Metazoa Species 0.000 claims 5
- 239000000654 additive Substances 0.000 claims 5
- 238000005341 cation exchange Methods 0.000 claims 5
- 230000002496 gastric effect Effects 0.000 claims 5
- 230000000996 additive effect Effects 0.000 claims 4
- 229930002954 deoxynivalenol Natural products 0.000 claims 4
- LINOMUASTDIRTM-QGRHZQQGSA-N deoxynivalenol Chemical compound C([C@@]12[C@@]3(C[C@@H](O)[C@H]1O[C@@H]1C=C(C([C@@H](O)[C@@]13CO)=O)C)C)O2 LINOMUASTDIRTM-QGRHZQQGSA-N 0.000 claims 4
- 239000000463 material Substances 0.000 claims 4
- LINOMUASTDIRTM-UHFFFAOYSA-N vomitoxin hydrate Natural products OCC12C(O)C(=O)C(C)=CC1OC1C(O)CC2(C)C11CO1 LINOMUASTDIRTM-UHFFFAOYSA-N 0.000 claims 4
- 125000000217 alkyl group Chemical group 0.000 claims 3
- 150000001875 compounds Chemical class 0.000 claims 3
- ADFIQZBYNGPCGY-HTJQZXIKSA-N 3-acetyldeoxynivalenol Chemical compound C([C@]12[C@]3(C)C[C@H]([C@H]2O[C@H]2[C@@]3([C@H](O)C(=O)C(C)=C2)CO)OC(=O)C)O1 ADFIQZBYNGPCGY-HTJQZXIKSA-N 0.000 claims 2
- IDGRYIRJIFKTAN-UHFFFAOYSA-N 3-acetyldeoxynivalenol Natural products CC(=O)OCC12C(O)C(=O)C(C)=CC1OC1C(O)CC2(C)C11CO1 IDGRYIRJIFKTAN-UHFFFAOYSA-N 0.000 claims 2
- ADFIQZBYNGPCGY-UHFFFAOYSA-N Acetyldeoxynivalenol Natural products C1=C(C)C(=O)C(O)C2(CO)C1OC1C(OC(=O)C)CC2(C)C21CO2 ADFIQZBYNGPCGY-UHFFFAOYSA-N 0.000 claims 2
- 206010012735 Diarrhoea Diseases 0.000 claims 2
- XGCUCFKWVIWWNW-UHFFFAOYSA-N Fusarenone X Natural products CC(=O)OC1C(O)C2OC3C=C(C)C(=O)C(O)C3(CO)C1(C)C21CO1 XGCUCFKWVIWWNW-UHFFFAOYSA-N 0.000 claims 2
- PNKLMTPXERFKEN-MLXHEQMXSA-N HT-2 toxin Chemical compound C([C@@]12[C@]3(C)[C@H](O)[C@@H](O)[C@H]1O[C@H]1[C@]3(COC(C)=O)C[C@@H](C(=C1)C)OC(=O)CC(C)C)O2 PNKLMTPXERFKEN-MLXHEQMXSA-N 0.000 claims 2
- 206010061218 Inflammation Diseases 0.000 claims 2
- TVZHDVCTOCZDNE-UHFFFAOYSA-N Neosolaniol Natural products CC(=O)OCC12CC(O)C(C)=CC1OC1C(O)C(OC(C)=O)C2(C)C11CO1 TVZHDVCTOCZDNE-UHFFFAOYSA-N 0.000 claims 2
- ITCSWEBPTQLQKN-UHFFFAOYSA-N Nivalenol Natural products CC1=CC2OC3C(O)C(O)C(C2(CO)CC1=O)C34CO4 ITCSWEBPTQLQKN-UHFFFAOYSA-N 0.000 claims 2
- UKOTXHQERFPCBU-YQPARWETSA-N Nivalenol Chemical compound C([C@]12[C@@]3([C@H](O)[C@@H](O)[C@H]1O[C@@H]1C=C(C([C@@H](O)[C@@]13CO)=O)C)C)O2 UKOTXHQERFPCBU-YQPARWETSA-N 0.000 claims 2
- BXFOFFBJRFZBQZ-QYWOHJEZSA-N T-2 toxin Chemical compound C([C@@]12[C@]3(C)[C@H](OC(C)=O)[C@@H](O)[C@H]1O[C@H]1[C@]3(COC(C)=O)C[C@@H](C(=C1)C)OC(=O)CC(C)C)O2 BXFOFFBJRFZBQZ-QYWOHJEZSA-N 0.000 claims 2
- 206010047700 Vomiting Diseases 0.000 claims 2
- 239000012736 aqueous medium Substances 0.000 claims 2
- 230000000740 bleeding effect Effects 0.000 claims 2
- XGCUCFKWVIWWNW-CAYGJDLQSA-N fusarenone x Chemical compound C([C@@]12[C@@]3(C)[C@@]4(CO)[C@H](O)C(=O)C(C)=C[C@H]4O[C@@H]1[C@H](O)[C@H]3OC(=O)C)O2 XGCUCFKWVIWWNW-CAYGJDLQSA-N 0.000 claims 2
- 230000004054 inflammatory process Effects 0.000 claims 2
- 125000002496 methyl group Chemical group [H]C([H])([H])* 0.000 claims 2
- 230000017074 necrotic cell death Effects 0.000 claims 2
- TVZHDVCTOCZDNE-WVJYZQHISA-N neosolaniol Chemical compound C([C@@]12[C@]3(C)[C@H](OC(C)=O)[C@@H](O)[C@H]1O[C@@H]1C=C(C)[C@@H](O)C[C@@]13COC(=O)C)O2 TVZHDVCTOCZDNE-WVJYZQHISA-N 0.000 claims 2
- 230000002265 prevention Effects 0.000 claims 2
- 230000008673 vomiting Effects 0.000 claims 2
- ZAMOUSCENKQFHK-UHFFFAOYSA-N Chlorine atom Chemical group [Cl] ZAMOUSCENKQFHK-UHFFFAOYSA-N 0.000 claims 1
- GDTBXPJZTBHREO-UHFFFAOYSA-N bromine Substances BrBr GDTBXPJZTBHREO-UHFFFAOYSA-N 0.000 claims 1
- 229910052794 bromium Inorganic materials 0.000 claims 1
- 125000001246 bromo group Chemical group Br* 0.000 claims 1
- 125000004432 carbon atom Chemical group C* 0.000 claims 1
- 239000003795 chemical substances by application Substances 0.000 claims 1
- 229910052801 chlorine Chemical group 0.000 claims 1
- 239000000460 chlorine Chemical group 0.000 claims 1
- UHZZMRAGKVHANO-UHFFFAOYSA-M chlormequat chloride Chemical compound [Cl-].C[N+](C)(C)CCCl UHZZMRAGKVHANO-UHFFFAOYSA-M 0.000 claims 1
- 238000001035 drying Methods 0.000 claims 1
- 230000008030 elimination Effects 0.000 claims 1
- 238000003379 elimination reaction Methods 0.000 claims 1
- 238000001914 filtration Methods 0.000 claims 1
- 229910052736 halogen Inorganic materials 0.000 claims 1
- 150000002367 halogens Chemical group 0.000 claims 1
- 239000000203 mixture Substances 0.000 claims 1
- 229910052615 phyllosilicate Inorganic materials 0.000 claims 1
- 238000002360 preparation method Methods 0.000 claims 1
- 238000001179 sorption measurement Methods 0.000 claims 1
- 238000003756 stirring Methods 0.000 claims 1
- 229910052645 tectosilicate Inorganic materials 0.000 claims 1
- 230000001225 therapeutic effect Effects 0.000 claims 1
- 0 *c1ccc(C=*)cc1 Chemical compound *c1ccc(C=*)cc1 0.000 description 2
- BFFUBOLNTYQJJE-UHFFFAOYSA-N CCCCCCCCCc(cc1)ccc1OCCOCCOCCOCCOCCOCCOCCOCCOCCOCCC(C)(C)Cc1ccccc1 Chemical compound CCCCCCCCCc(cc1)ccc1OCCOCCOCCOCCOCCOCCOCCOCCOCCOCCC(C)(C)Cc1ccccc1 BFFUBOLNTYQJJE-UHFFFAOYSA-N 0.000 description 1
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| MXMX/A/2013/013788 | 2013-11-25 | ||
| MX2013013788A MX338482B (es) | 2013-11-25 | 2013-11-25 | Absorbente de micotoxinas y su uso en alimentos balanceados para animales. |
| PCT/IB2014/066246 WO2015075686A1 (es) | 2013-11-25 | 2014-11-21 | Absorbente de micotoxinas y su uso en alimentos balanceados para animales |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2016539949A JP2016539949A (ja) | 2016-12-22 |
| JP2016539949A5 true JP2016539949A5 (enExample) | 2017-12-07 |
| JP6387097B2 JP6387097B2 (ja) | 2018-09-05 |
Family
ID=53179054
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2016535014A Expired - Fee Related JP6387097B2 (ja) | 2013-11-25 | 2014-11-21 | マイコトキシン吸着剤及びその動物用配合飼料における使用 |
Country Status (11)
| Country | Link |
|---|---|
| US (1) | US20160287617A1 (enExample) |
| EP (1) | EP3075260B1 (enExample) |
| JP (1) | JP6387097B2 (enExample) |
| CN (1) | CN105792665B (enExample) |
| CA (1) | CA2930547C (enExample) |
| CL (1) | CL2016001264A1 (enExample) |
| ES (1) | ES2761568T3 (enExample) |
| MX (1) | MX338482B (enExample) |
| PE (1) | PE20160684A1 (enExample) |
| RS (1) | RS59791B1 (enExample) |
| WO (1) | WO2015075686A1 (enExample) |
Families Citing this family (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| MX354792B (es) * | 2016-06-22 | 2018-03-21 | Nutek S A De C V | Adsorbente de micotoxinas con base en un derivado de betaina para alimentos balanceados de animales. |
| EP3430913B1 (en) | 2017-07-20 | 2020-12-02 | Tolsa, S.A. | Composition for binding mycotoxins and its use |
| EP3840590A4 (en) * | 2018-08-20 | 2022-05-18 | Texas A&M University | Edible enterosorbents used to mitigate acute exposures to ingestible environmental toxins following outbreaks, natural disasters and emergencies |
| CN109364885B (zh) * | 2018-11-24 | 2021-03-12 | 烟台大学 | 羧甲基纤维素钠-胶原-蒙脱土复合黄曲霉菌吸附材料的制备方法 |
| CN109939648B (zh) * | 2019-03-15 | 2023-04-14 | 上海岩康生物科技有限公司 | 一种复合型广谱性霉菌毒素吸附剂及其制备方法 |
| CN110776568B (zh) * | 2019-11-15 | 2023-04-18 | 中国农业科学院油料作物研究所 | 净化伏马毒素b1、蛇形毒素、t-2毒素、玉米赤霉烯酮、呕吐毒素复合亲和柱 |
| CN111298775B (zh) * | 2020-03-03 | 2022-04-26 | 武汉轻工大学 | 一种甲壳素磁性微球吸附剂及其制备方法和应用 |
| DE102020115832B3 (de) | 2020-06-16 | 2021-12-16 | AdFiS products GmbH | Mykotoxin-Adsorber auf Basis von Aktivkohle |
| WO2022243722A1 (es) * | 2021-05-17 | 2022-11-24 | Nutek, S.A. De C.V. | Uso de un adsorbente de fumonisina b1 y zearalenona en alimentos balanceados para animales |
| CN113713777B (zh) * | 2021-09-13 | 2024-01-09 | 湖南农业大学 | 蛋壳粉呕吐毒素吸附剂的制备方法 |
Family Cites Families (18)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CH443774A (de) * | 1963-05-30 | 1967-09-15 | Ciba Geigy | Mittel zur Bekämpfung phytopathogener Mikroorganismen |
| DE3126522A1 (de) * | 1981-07-04 | 1983-01-20 | Basf Ag, 6700 Ludwigshafen | Quaternaere ammoniumsalze und verfahren zu ihrer herstellung |
| DE3810004A1 (de) | 1988-03-24 | 1989-10-05 | Siegfried Dr Moser | Verwendung von bentoniten zur mykotoxinbindung |
| BR9105978A (pt) | 1990-03-07 | 1992-11-17 | Engelhard Corp | Aditivo de forragem particulado,e composicao de forragem |
| DE19900813A1 (de) | 1999-01-12 | 2000-07-13 | Sued Chemie Ag | Mykotoxin-Adsorbens |
| MXPA00007077A (es) * | 2000-07-19 | 2003-09-08 | Nutek S A De C V | Proceso para preparar organoaluminosilicatos y su uso en alimentos balanceados para animales. |
| DE10056634A1 (de) | 2000-11-15 | 2002-05-29 | Sued Chemie Ag | Verwendung Aktivierter Schichtsilicate zur Mykotoxinadsorption |
| HUP0300377A3 (en) * | 2000-12-28 | 2003-07-28 | Inst Za Technologiju Nuklearni | Organomineral adsorbent of mycotoxin as an animal feed additive, procedure for production and application |
| DE60232058D1 (de) * | 2001-02-15 | 2009-06-04 | Patent Co | Verfahren zur tribochemischen gewinnung eines organozeolithen als adsorbens für mycotoxine, |
| ZA200710203B (en) | 2005-05-10 | 2010-08-25 | Sued Chemie Ag | Use of stevensite for mycotoxin adsorption |
| JP4295761B2 (ja) * | 2005-12-27 | 2009-07-15 | 学校法人酪農学園 | マイコトキシン除去用飼料添加剤 |
| US9597313B2 (en) * | 2006-06-27 | 2017-03-21 | Timothy D. Phillips | Composition and methods for the enterosorption and management of toxins |
| KR20090034506A (ko) * | 2007-10-04 | 2009-04-08 | 주식회사 카이로라이트 | 악취 및 ＶＯＣ'ｓ 제거기능을 갖는 친유성 실리케이트 및그 제조방법 |
| EP2279787B1 (en) | 2009-06-29 | 2012-08-08 | Adiveter S.L. | Mycotoxin adsorbent |
| EP2289617A1 (en) | 2009-08-27 | 2011-03-02 | Süd-Chemie AG | Toxin adsorbent |
| WO2012037297A1 (en) | 2010-09-16 | 2012-03-22 | Cubena, Inc. | Mycotoxin binding food and feed additives and processing aids, fungistatic and bacteriostatic plant protecting agents and methods of utilizing the same |
| ES2690550T3 (es) * | 2011-01-13 | 2018-11-21 | Austin Research Labs Corp. | Dispersiones de alta carga para el tratamiento de infecciones |
| CN102847509B (zh) * | 2012-04-17 | 2014-05-14 | 东北农业大学 | 一种饲料霉菌毒素吸附剂及其制备方法 |
-
2013
- 2013-11-25 MX MX2013013788A patent/MX338482B/es active IP Right Grant
-
2014
- 2014-11-21 US US15/037,661 patent/US20160287617A1/en not_active Abandoned
- 2014-11-21 EP EP14864455.2A patent/EP3075260B1/en not_active Not-in-force
- 2014-11-21 ES ES14864455T patent/ES2761568T3/es active Active
- 2014-11-21 JP JP2016535014A patent/JP6387097B2/ja not_active Expired - Fee Related
- 2014-11-21 RS RS20191577A patent/RS59791B1/sr unknown
- 2014-11-21 PE PE2016000612A patent/PE20160684A1/es unknown
- 2014-11-21 WO PCT/IB2014/066246 patent/WO2015075686A1/es not_active Ceased
- 2014-11-21 CA CA2930547A patent/CA2930547C/en not_active Expired - Fee Related
- 2014-11-21 CN CN201480063868.4A patent/CN105792665B/zh not_active Expired - Fee Related
-
2016
- 2016-05-24 CL CL2016001264A patent/CL2016001264A1/es unknown
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| JP2016539949A5 (enExample) | ||
| Lange et al. | Grape seed extract and dried macroalgae, Ulva lactuca Linnaeus, improve survival of greenlip abalone, Haliotis laevigata Donovan, at high water temperature | |
| MX2021013299A (es) | Derivados de acido itaconico y usos de estos en el tratamiento de una enfermedad inflamatoria asociada con una respuesta inmunitaria indeseable. | |
| EA201691590A1 (ru) | Бензимидазол-2-амины в качестве ингибиторов midhi | |
| JP2016523256A5 (enExample) | ||
| TR201909093T4 (tr) | Hidroksi içeren FXR (NR1H4) modüle edici bileşikleri. | |
| EA201791002A1 (ru) | Новые соединения, модулирующие fxr (nr1h4) | |
| JP2016041733A5 (enExample) | ||
| JP2016532706A5 (enExample) | ||
| JP6387097B2 (ja) | マイコトキシン吸着剤及びその動物用配合飼料における使用 | |
| CN108026053A8 (zh) | 作为mIDH1抑制剂的稠合的咪唑类化合物 | |
| EA201790519A1 (ru) | Терапевтические соединения в качестве ингибиторов рецептора орексина-1 | |
| HRP20171611T1 (hr) | N-(4-hidroksi-4-metil-cikloheksil)-4-fenil-benzensulfonamidi i n-(4-hidroksi-4-metil-cikloheksil)-4-(2-piridil)-benzensulfonamidi i njihova terapeutska primjena | |
| EA201700042A1 (ru) | Соединения имидазопиридазина | |
| JP2016515388A5 (enExample) | ||
| CN112004801A (zh) | 一种c-MET 抑制剂的晶型及其盐型和制备方法 | |
| MX2022007671A (es) | Compuestos antihelminticos que comprenden una estructura de azaindoles. | |
| MX2019014935A (es) | Antagonistas muscarinicos y sus combinaciones para el tratamiento de enfermedades de las vias respiratorias en caballos. | |
| PH12016501932A1 (en) | Amido-substituted azole compounds | |
| HRP20190737T1 (hr) | Stelja za perad | |
| MX353966B (es) | Tratamiento de aves de corral, cerdos o peces para reducir la relacion de conversion de alimento o incrementar su ganancia de peso corporal. | |
| JP2018008180A5 (enExample) | ||
| JP2016526379A5 (enExample) | ||
| JP2015030778A5 (enExample) | ||
| JP2016505026A5 (enExample) |