JP2016528198A5 - - Google Patents
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- JP2016528198A5 JP2016528198A5 JP2016524371A JP2016524371A JP2016528198A5 JP 2016528198 A5 JP2016528198 A5 JP 2016528198A5 JP 2016524371 A JP2016524371 A JP 2016524371A JP 2016524371 A JP2016524371 A JP 2016524371A JP 2016528198 A5 JP2016528198 A5 JP 2016528198A5
- Authority
- JP
- Japan
- Prior art keywords
- seq
- antibody
- diabetes
- antibody fragment
- pharmaceutical composition
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201361842745P | 2013-07-03 | 2013-07-03 | |
| US61/842,745 | 2013-07-03 | ||
| US201461982611P | 2014-04-22 | 2014-04-22 | |
| US61/982,611 | 2014-04-22 | ||
| PCT/US2014/045389 WO2015003122A2 (en) | 2013-07-03 | 2014-07-03 | Regulation of glucose metabolism using anti-cgrp antibodies |
Related Child Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2018128766A Division JP2018168186A (ja) | 2013-07-03 | 2018-07-06 | 抗ｃｇｒｐ抗体を使用したグルコース代謝の調整 |
| JP2019052046A Division JP2019112455A (ja) | 2013-07-03 | 2019-03-20 | 抗ｃｇｒｐ抗体を使用したグルコース代謝の調整 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2016528198A JP2016528198A (ja) | 2016-09-15 |
| JP2016528198A5 true JP2016528198A5 (https=) | 2017-08-10 |
| JP6502337B2 JP6502337B2 (ja) | 2019-04-17 |
Family
ID=52144290
Family Applications (4)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2016524371A Active JP6502337B2 (ja) | 2013-07-03 | 2014-07-03 | 抗ｃｇｒｐ抗体を使用したグルコース代謝の調整 |
| JP2018128766A Withdrawn JP2018168186A (ja) | 2013-07-03 | 2018-07-06 | 抗ｃｇｒｐ抗体を使用したグルコース代謝の調整 |
| JP2019052046A Pending JP2019112455A (ja) | 2013-07-03 | 2019-03-20 | 抗ｃｇｒｐ抗体を使用したグルコース代謝の調整 |
| JP2020104177A Pending JP2020158525A (ja) | 2013-07-03 | 2020-06-17 | 抗ｃｇｒｐ抗体を使用したグルコース代謝の調整 |
Family Applications After (3)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2018128766A Withdrawn JP2018168186A (ja) | 2013-07-03 | 2018-07-06 | 抗ｃｇｒｐ抗体を使用したグルコース代謝の調整 |
| JP2019052046A Pending JP2019112455A (ja) | 2013-07-03 | 2019-03-20 | 抗ｃｇｒｐ抗体を使用したグルコース代謝の調整 |
| JP2020104177A Pending JP2020158525A (ja) | 2013-07-03 | 2020-06-17 | 抗ｃｇｒｐ抗体を使用したグルコース代謝の調整 |
Country Status (14)
| Country | Link |
|---|---|
| US (1) | US20150017166A1 (https=) |
| EP (1) | EP3016684B1 (https=) |
| JP (4) | JP6502337B2 (https=) |
| KR (1) | KR102476907B1 (https=) |
| CN (1) | CN105492026B (https=) |
| AU (2) | AU2014285052B2 (https=) |
| CA (1) | CA2916980C (https=) |
| ES (1) | ES2911690T3 (https=) |
| IL (1) | IL243355B2 (https=) |
| MX (1) | MX374612B (https=) |
| NZ (1) | NZ754427A (https=) |
| SG (2) | SG10201906172XA (https=) |
| TW (2) | TWI712419B (https=) |
| WO (1) | WO2015003122A2 (https=) |
Families Citing this family (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| IL243355B2 (en) * | 2013-07-03 | 2024-10-01 | Lundbeck Seattle Biopharmaceuticals Inc | Regulation of glucose metabolism using anti-cgrp antibodies |
| AU2015230933B2 (en) | 2014-03-21 | 2020-08-13 | Teva Pharmaceuticals International Gmbh | Antagonist antibodies directed against calcitonin gene-related peptide and methods using same |
| US10556945B2 (en) | 2014-03-21 | 2020-02-11 | Teva Pharmaceuticals International Gmbh | Antagonist antibodies directed against calcitonin gene-related peptide and methods using same |
| US10588980B2 (en) | 2014-06-23 | 2020-03-17 | Novartis Ag | Fatty acids and their use in conjugation to biomolecules |
| CN109952314A (zh) | 2016-09-23 | 2019-06-28 | 泰瓦制药国际有限公司 | 治疗难治性偏头痛 |
| CA3077973A1 (en) | 2020-04-06 | 2021-10-06 | H. Lundbeck A/S | Treatment of most bothersome symptom (mbs) associated with migraine using anti-cgrp antibodies |
| CN116057185A (zh) * | 2020-08-15 | 2023-05-02 | 雷杰纳荣制药公司 | 治疗具有编码降钙素受体(calcr)的变体核酸分子的受试者的肥胖症 |
| IL310885A (en) | 2021-08-27 | 2024-04-01 | H Lundbeck As | Treatment of cluster headache using anti-CGRP antibodies |
| US20260001942A1 (en) | 2024-06-21 | 2026-01-01 | H. Lundbeck A/S | Treatment of headache disorders and/or psychiatric symptoms using anti-cgrp antibodies, and compositions and methods related thereto |
Family Cites Families (28)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4179337A (en) | 1973-07-20 | 1979-12-18 | Davis Frank F | Non-immunogenic polypeptides |
| GB8720115D0 (en) | 1987-08-26 | 1987-09-30 | Cooper G J S | Treatment of diabetes mellitus |
| GB8725529D0 (en) | 1987-10-30 | 1987-12-02 | Delta Biotechnology Ltd | Polypeptides |
| US5266561A (en) * | 1988-01-11 | 1993-11-30 | Amylin Pharmaceuticals, Inc. | Treatment of type 2 diabetes mellitus |
| US5364841A (en) * | 1988-01-11 | 1994-11-15 | Amylin Pharmaceuticals, Inc. | Treatment of obesity and essential hypertension and related disorders |
| AU631112B2 (en) * | 1988-01-11 | 1992-11-19 | Amylin Corporation | Treatment of type 2 diabetes mellitus |
| US5175145A (en) | 1988-08-26 | 1992-12-29 | Amylin Pharmaceuticals, Inc. | Treatment of diabetes mellitus with amylin agonists |
| WO1990006952A1 (fr) | 1988-12-22 | 1990-06-28 | Kirin-Amgen, Inc. | Facteur de stimulation de colonies de granulocytes modifies chimiquement |
| JPH0666358B2 (ja) * | 1989-01-03 | 1994-08-24 | モトローラ・インコーポレーテッド | 高密度ソルダ・バンプの製造方法と高密度ソルダ・バンプ用基板ソケット |
| US5766883A (en) | 1989-04-29 | 1998-06-16 | Delta Biotechnology Limited | Polypeptides |
| ES2080802T3 (es) * | 1989-07-10 | 1996-02-16 | Amylin Pharmaceuticals Inc | Uso de un antagonista de amilina en la preparacion de un medicamento para el tratamiento de la obesidad e hipertension intrinseca y desordenes asociados. |
| FR2650598B1 (fr) | 1989-08-03 | 1994-06-03 | Rhone Poulenc Sante | Derives de l'albumine a fonction therapeutique |
| CA2090126C (en) | 1990-08-02 | 2002-10-22 | John W. Schrader | Methods for the production of proteins with a desired function |
| FR2686899B1 (fr) | 1992-01-31 | 1995-09-01 | Rhone Poulenc Rorer Sa | Nouveaux polypeptides biologiquement actifs, leur preparation et compositions pharmaceutiques les contenant. |
| AU6445894A (en) | 1993-03-19 | 1994-10-11 | Duke University | Method of treatment of tumors with an antibody binding to tenascin |
| US5643575A (en) | 1993-10-27 | 1997-07-01 | Enzon, Inc. | Non-antigenic branched polymer conjugates |
| DE69534530T2 (de) | 1994-08-12 | 2006-07-06 | Immunomedics, Inc. | Für b-zell-lymphom und leukämiezellen spezifische immunkonjugate und humane antikörper |
| US6653104B2 (en) | 1996-10-17 | 2003-11-25 | Immunomedics, Inc. | Immunotoxins, comprising an internalizing antibody, directed against malignant and normal cells |
| EP1461068A4 (en) * | 2001-11-26 | 2006-03-29 | Protemix Corp Ltd | METHOD AND COMPOSITIONS FOR NORMALIZING LIPID MIRRORS IN MIRACLE TISSUE |
| CA2541651C (en) | 2003-10-22 | 2011-05-24 | Keck Graduate Institute | Methods of synthesizing heteromultimeric polypeptides in yeast using a haploid mating strategy |
| EP3069731A1 (en) * | 2005-11-14 | 2016-09-21 | Labrys Biologics Inc. | Antagonist antibodies directed against calcitonin gene-related peptide and methods using same |
| EP2021463B1 (en) | 2006-05-19 | 2016-11-23 | Alder Biopharmaceuticals, Inc. | Culture method for obtaining a clonal population of antigen-specific b cells |
| KR20170036814A (ko) | 2007-05-21 | 2017-04-03 | 앨더바이오 홀딩스 엘엘씨 | 신규한 래빗 항체 인간화 방법 및 인간화된 래빗 항체 |
| TW201531484A (zh) | 2007-05-21 | 2015-08-16 | Alder Biopharmaceuticals Inc | 抗ＴＮＦ-α之抗體及其用途 |
| DK2164514T3 (en) | 2007-05-21 | 2017-02-27 | Alderbio Holdings Llc | Antibodies to IL-6 and its use |
| PE20141787A1 (es) * | 2011-05-20 | 2014-12-07 | Alderbio Holdings Llc | Composiciones anti-cgrp y uso de las mismas |
| TWI705825B (zh) * | 2011-05-20 | 2020-10-01 | 美商艾爾德生物控股有限責任公司 | 抗降血鈣素基因相關胜肽（ａｎｔｉ－ｃｇｒｐ）或抗降血鈣素基因相關胜肽受器（ａｎｔｉ－ｃｇｒｐ－ｒ）抗體或抗體片段治療或預防慢性及急性型腹瀉之用途 |
| IL243355B2 (en) * | 2013-07-03 | 2024-10-01 | Lundbeck Seattle Biopharmaceuticals Inc | Regulation of glucose metabolism using anti-cgrp antibodies |
-
2014
- 2014-07-03 IL IL243355A patent/IL243355B2/en unknown
- 2014-07-03 EP EP14820173.4A patent/EP3016684B1/en active Active
- 2014-07-03 AU AU2014285052A patent/AU2014285052B2/en active Active
- 2014-07-03 SG SG10201906172XA patent/SG10201906172XA/en unknown
- 2014-07-03 TW TW103122993A patent/TWI712419B/zh active
- 2014-07-03 JP JP2016524371A patent/JP6502337B2/ja active Active
- 2014-07-03 MX MX2016000220A patent/MX374612B/es active IP Right Grant
- 2014-07-03 SG SG11201510618YA patent/SG11201510618YA/en unknown
- 2014-07-03 US US14/323,028 patent/US20150017166A1/en not_active Abandoned
- 2014-07-03 CA CA2916980A patent/CA2916980C/en active Active
- 2014-07-03 TW TW109121891A patent/TWI753471B/zh active
- 2014-07-03 ES ES14820173T patent/ES2911690T3/es active Active
- 2014-07-03 NZ NZ754427A patent/NZ754427A/en unknown
- 2014-07-03 KR KR1020167002907A patent/KR102476907B1/ko active Active
- 2014-07-03 WO PCT/US2014/045389 patent/WO2015003122A2/en not_active Ceased
- 2014-07-03 CN CN201480047723.5A patent/CN105492026B/zh active Active
-
2018
- 2018-07-06 JP JP2018128766A patent/JP2018168186A/ja not_active Withdrawn
-
2019
- 2019-03-20 JP JP2019052046A patent/JP2019112455A/ja active Pending
- 2019-12-10 AU AU2019279945A patent/AU2019279945B2/en active Active
-
2020
- 2020-06-17 JP JP2020104177A patent/JP2020158525A/ja active Pending
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