JP2016526571A5 - - Google Patents
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- Publication number
- JP2016526571A5 JP2016526571A5 JP2016525409A JP2016525409A JP2016526571A5 JP 2016526571 A5 JP2016526571 A5 JP 2016526571A5 JP 2016525409 A JP2016525409 A JP 2016525409A JP 2016525409 A JP2016525409 A JP 2016525409A JP 2016526571 A5 JP2016526571 A5 JP 2016526571A5
- Authority
- JP
- Japan
- Prior art keywords
- och
- acceptable salt
- pharmaceutically acceptable
- pain
- compound
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201361844499P | 2013-07-10 | 2013-07-10 | |
| US61/844,499 | 2013-07-10 | ||
| PCT/US2014/045675 WO2015006280A1 (en) | 2013-07-10 | 2014-07-08 | Fused piperidine amides as modulators of ion channels |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2016526571A JP2016526571A (ja) | 2016-09-05 |
| JP2016526571A5 true JP2016526571A5 (cg-RX-API-DMAC10.html) | 2017-08-17 |
| JP6605462B2 JP6605462B2 (ja) | 2019-11-13 |
Family
ID=51230209
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2016525409A Expired - Fee Related JP6605462B2 (ja) | 2013-07-10 | 2014-07-08 | イオンチャネルのモジュレーターとしての縮合ピペリジンアミド |
Country Status (13)
| Country | Link |
|---|---|
| US (1) | US10233191B2 (cg-RX-API-DMAC10.html) |
| EP (1) | EP3019478B1 (cg-RX-API-DMAC10.html) |
| JP (1) | JP6605462B2 (cg-RX-API-DMAC10.html) |
| KR (1) | KR102306951B1 (cg-RX-API-DMAC10.html) |
| CN (1) | CN105473554B (cg-RX-API-DMAC10.html) |
| AU (1) | AU2014287471C1 (cg-RX-API-DMAC10.html) |
| CA (1) | CA2917198C (cg-RX-API-DMAC10.html) |
| ES (1) | ES2780699T3 (cg-RX-API-DMAC10.html) |
| IL (1) | IL243495B (cg-RX-API-DMAC10.html) |
| MX (1) | MX368728B (cg-RX-API-DMAC10.html) |
| RU (1) | RU2741810C2 (cg-RX-API-DMAC10.html) |
| SG (1) | SG11201600082VA (cg-RX-API-DMAC10.html) |
| WO (1) | WO2015006280A1 (cg-RX-API-DMAC10.html) |
Families Citing this family (22)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN108699015A (zh) | 2015-12-18 | 2018-10-23 | 默沙东公司 | 对电压门控性钠通道具有选择性活性的羟基烷基胺-和羟基环烷基胺-取代的二胺-芳基磺胺化合物 |
| KR102079844B1 (ko) | 2016-09-20 | 2020-02-20 | 가톨릭대학교 산학협력단 | 담석 용해제를 포함하는 담낭 질환 치료용 약학 조성물 |
| US11071721B2 (en) | 2016-12-02 | 2021-07-27 | Genentech, Inc. | Bicyclic amide compounds and methods of use thereof |
| WO2018155260A1 (ja) * | 2017-02-23 | 2018-08-30 | 株式会社Ihi | Ｏｈラジカル検出プローブ、ｏｈラジカル測定装置、および、ｏｈラジカル測定方法 |
| CN119613408A (zh) | 2017-07-14 | 2025-03-14 | 豪夫迈·罗氏有限公司 | 二环酮化合物及其使用方法 |
| CN109574927A (zh) * | 2017-09-29 | 2019-04-05 | 浙江海正药业股份有限公司 | N-(取代磺酰基)苯甲酰胺类衍生物及其制备方法和医药用途 |
| MX2020003451A (es) | 2017-10-31 | 2020-08-03 | Hoffmann La Roche | Sulfonas y sulfoxidos biciclicos y metodos de uso de los mismos. |
| WO2020054657A1 (ja) * | 2018-09-10 | 2020-03-19 | 科研製薬株式会社 | 新規ヘテロ芳香族アミド誘導体及びそれを含有する医薬 |
| CN113302193B (zh) | 2019-01-11 | 2026-05-29 | 豪夫迈·罗氏有限公司 | 双环吡咯并三唑酮化合物及其使用方法 |
| TWI775313B (zh) | 2020-02-18 | 2022-08-21 | 美商基利科學股份有限公司 | 抗病毒化合物 |
| KR20250133471A (ko) | 2020-02-18 | 2025-09-05 | 길리애드 사이언시즈, 인코포레이티드 | 항바이러스 화합물 |
| TWI794742B (zh) | 2020-02-18 | 2023-03-01 | 美商基利科學股份有限公司 | 抗病毒化合物 |
| AU2022256476B2 (en) | 2021-04-16 | 2025-06-05 | Gilead Sciences, Inc. | Methods of preparing carbanucleosides using amides |
| UY39881A (es) | 2021-08-02 | 2023-06-15 | Eurofarma Laboratorios S A | “COMPUESTOS N-ACILHIDRAZÓNICOS INHIBIDORES DE Nav 1.7 Y/O Nav 1.8, SUS PROCESOS DE OBTENCIÓN, COMPOSICIONES, USOS, MÉTODOS DE TRATAMIENTO DE ESTOS Y KITS” |
| UY39882A (es) | 2021-08-02 | 2023-06-15 | Eurofarma Laboratorios S A | COMPUESTOS NACILHIDRAZÓNICOS INHIBIDORES DE Nav 1.7 Y/O Nav 1.8, SUS PROCESOS DE OBTENCIÓN, COMPOSICIONES, USOS, MÉTODOS DE TRATAMIENTO DE ESTOS Y KITS |
| CA3228162A1 (en) | 2021-08-18 | 2023-02-23 | Gilead Sciences, Inc. | Phospholipid compounds and methods of making and using the same |
| WO2024159287A1 (pt) | 2023-01-30 | 2024-08-08 | Eurofarma Laboratórios S.A. | Hidroxamatos bloqueadores de nav 1.7 e/ou nav 1.8, seus processos de obtenção, composições, usos, métodos de tratamento destes e kits |
| AR131715A1 (es) | 2023-01-30 | 2025-04-23 | Eurofarma Laboratorios S A | AMIDAS BLOQUEADORAS DE Nav 1.7 Y/O Nav 1.8, SUS PROCESOS DE OBTENCIÓN, COMPOSICIONES, USOS, MÉTODOS DE TRATAMIENTO DE LOS MISMOS Y KITS |
| PY2404093A (es) | 2023-01-30 | 2024-10-03 | Eurofarma Laboratorios S A | Hidrazidas bloqueadoras de nav 1.7 y/o nav 1.8, sus procesos de obtención, composiciones, usos, métodos de tratamiento de los mismos y kits |
| WO2024159285A1 (pt) | 2023-01-30 | 2024-08-08 | Eurofarma Laboratórios S.A. | Compostos aril piridinas bloqueadores de nav 1.7 e/ou nav 1.8, seus processos de obtenção, composições, usos, métodos de tratamento destes e kits |
| PY2404641A (es) | 2023-01-30 | 2024-10-03 | Eurofarma Laboratorios S A | COMPUESTOS FENÓLICOS BLOQUEADORES DE Nav 1.7 Y/O Nav 1.8, SUS PROCESOS DE OBTENCIÓN, SUS COMPOSICIONES, SUS USOS, LOS MÉTODOS DE TRATAMIENTO DE LOS MISMOS Y SUS KITS |
| CN119285621B (zh) * | 2024-12-13 | 2025-07-18 | 嘉兴安帝康生物科技有限公司 | 作为钠通道调节剂的四氢呋喃甲酰胺类化合物及其在医药上的应用 |
Family Cites Families (15)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3549641A (en) * | 1966-06-28 | 1970-12-22 | Warner Lambert Pharmaceutical | Pyrano pyridines and process for their production |
| SE7509022L (sv) | 1974-09-09 | 1976-03-10 | Du Pont | Foreningar med analgetisk verkan |
| DE2655150A1 (de) | 1975-12-16 | 1977-06-23 | Sandoz Ag | Neue organische verbindungen, ihre herstellung und verwendung |
| US4301290A (en) * | 1975-12-16 | 1981-11-17 | Sandoz Ltd. | Organic compounds |
| PT68934A (en) * | 1977-12-27 | 1979-01-01 | Lilly Co Eli | Process for preparing 4a-aryl-octahydro-1h-2-pyrindines |
| DE2907461A1 (de) * | 1978-03-10 | 1979-09-20 | Sandoz Ag | Isochinolinderivate, ihre herstellung und diese enthaltende pharmazeutische zubereitungen |
| DE4427648A1 (de) | 1994-08-04 | 1996-02-08 | Basf Ag | N-Stubstituierte 3-Azabicyclo[3,2,0,]heptan-Derivate, ihre Herstellung und Verwendung |
| DE4341402A1 (de) | 1993-12-04 | 1995-06-08 | Basf Ag | N-substituierte Azabicycloheptan-Derivate, ihre Herstellung und Verwendung |
| JP2003327534A (ja) * | 1999-11-30 | 2003-11-19 | Toray Ind Inc | 頻尿若しくは尿失禁の治療又は予防剤 |
| EP1663994B1 (en) * | 2003-08-05 | 2012-03-07 | Vertex Pharmaceuticals Incorporated | Tetrahydroquinazoline compounds as inhibitors of voltage-gated ion channels |
| WO2008130319A2 (en) * | 2007-04-23 | 2008-10-30 | Astrazeneca Ab | Novel n-tetrahydronaphtalene or n-chromane carboxamide derivatives for the treatment of pain |
| WO2009005459A1 (en) * | 2007-06-29 | 2009-01-08 | Astrazeneca Ab | Phenyl-1,2, 3,4-tetrahydroisoquinolinone derivatives and their use in the treatment of a pain disorder |
| WO2010151597A1 (en) * | 2009-06-26 | 2010-12-29 | Schering Corporation | Methods for using pyrrolo-benzo-1,4-diazines as sodium channel blockers |
| EP2491034B1 (en) * | 2009-10-23 | 2013-12-18 | Janssen Pharmaceutica, N.V. | Fused heterocyclic compounds as orexin receptor modulators |
| KR101923367B1 (ko) * | 2011-02-02 | 2018-12-04 | 버텍스 파마슈티칼스 인코포레이티드 | 이온 채널의 조절제로서의 피롤로피라진―스피로사이클릭 피페리딘 아미드 |
-
2014
- 2014-07-08 AU AU2014287471A patent/AU2014287471C1/en not_active Ceased
- 2014-07-08 US US14/903,475 patent/US10233191B2/en active Active
- 2014-07-08 EP EP14744707.2A patent/EP3019478B1/en active Active
- 2014-07-08 SG SG11201600082VA patent/SG11201600082VA/en unknown
- 2014-07-08 MX MX2016000038A patent/MX368728B/es active IP Right Grant
- 2014-07-08 RU RU2016104080A patent/RU2741810C2/ru active
- 2014-07-08 CA CA2917198A patent/CA2917198C/en active Active
- 2014-07-08 WO PCT/US2014/045675 patent/WO2015006280A1/en not_active Ceased
- 2014-07-08 CN CN201480045419.7A patent/CN105473554B/zh not_active Expired - Fee Related
- 2014-07-08 JP JP2016525409A patent/JP6605462B2/ja not_active Expired - Fee Related
- 2014-07-08 KR KR1020167003469A patent/KR102306951B1/ko not_active Expired - Fee Related
- 2014-07-08 ES ES14744707T patent/ES2780699T3/es active Active
-
2016
- 2016-01-07 IL IL243495A patent/IL243495B/en active IP Right Grant
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