|
ES2354607T3
(es)
|
2002-06-28 |
2011-03-16 |
Protiva Biotherapeutics Inc. |
Procedimiento y aparato para producir liposomas.
|
|
US20110244026A1
(en)
|
2009-12-01 |
2011-10-06 |
Braydon Charles Guild |
Delivery of mrna for the augmentation of proteins and enzymes in human genetic diseases
|
|
WO2012000104A1
(en)
|
2010-06-30 |
2012-01-05 |
Protiva Biotherapeutics, Inc. |
Non-liposomal systems for nucleic acid delivery
|
|
WO2012075040A2
(en)
|
2010-11-30 |
2012-06-07 |
Shire Human Genetic Therapies, Inc. |
mRNA FOR USE IN TREATMENT OF HUMAN GENETIC DISEASES
|
|
LT2717893T
(lt)
|
2011-06-08 |
2019-08-12 |
Translate Bio, Inc. |
Lipidų nanodalelių kompozicijos ir mrnr pristatymo būdai
|
|
DK3336082T3
(da)
|
2011-06-08 |
2020-04-27 |
Translate Bio Inc |
Spaltelige lipider
|
|
HUE041494T2
(hu)
|
2012-02-24 |
2019-05-28 |
Arbutus Biopharma Corp |
Trialkil-kationos lipidek és alkalmazási módszereik
|
|
ES2858523T3
(es)
|
2012-03-29 |
2021-09-30 |
Translate Bio Inc |
Nanopartículas neutras derivadas de lípidos
|
|
ES2868174T3
(es)
|
2012-03-29 |
2021-10-21 |
Translate Bio Ma Inc |
Lípidos catiónicos ionizables
|
|
US20150267192A1
(en)
|
2012-06-08 |
2015-09-24 |
Shire Human Genetic Therapies, Inc. |
Nuclease resistant polynucleotides and uses thereof
|
|
US10245229B2
(en)
|
2012-06-08 |
2019-04-02 |
Translate Bio, Inc. |
Pulmonary delivery of mRNA to non-lung target cells
|
|
AU2014236305B2
(en)
|
2013-03-14 |
2019-01-17 |
Ethris Gmbh |
CFTR mRNA compositions and related methods and uses
|
|
MX2015012865A
(es)
|
2013-03-14 |
2016-07-21 |
Shire Human Genetic Therapies |
Metodos para purificacion de arn mensajero.
|
|
PL2970456T3
(pl)
|
2013-03-14 |
2022-01-31 |
Translate Bio, Inc. |
Sposoby i kompozycje do dostarczania przeciwciał kodowanych mrna
|
|
PL4332576T3
(pl)
|
2013-03-15 |
2025-09-08 |
Translate Bio, Inc. |
Synergistyczne wzmocnienie dostarczania kwasów nukleinowych poprzez formulacje zmieszane
|
|
CN105555757A
(zh)
*
|
2013-07-23 |
2016-05-04 |
普洛体维生物治疗公司 |
用于递送信使rna的组合物和方法
|
|
JP2016538829A
(ja)
|
2013-10-03 |
2016-12-15 |
モデルナ セラピューティクス インコーポレイテッドＭｏｄｅｒｎａ Ｔｈｅｒａｐｅｕｔｉｃｓ，Ｉｎｃ． |
低密度リポタンパク質受容体をコードするポリヌクレオチド
|
|
EP3871696B1
(en)
|
2013-10-22 |
2025-03-19 |
Translate Bio, Inc. |
Lipid formulations for delivery of messenger rna
|
|
ES2954366T3
(es)
|
2013-10-22 |
2023-11-21 |
Translate Bio Inc |
Terapia de ácido ribonucleico mensajero para la deficiencia de argininosuccinato sintetasa
|
|
EP3574923A1
(en)
|
2013-10-22 |
2019-12-04 |
Translate Bio, Inc. |
Mrna therapy for phenylketonuria
|
|
CN105658800A
(zh)
|
2013-10-22 |
2016-06-08 |
夏尔人类遗传性治疗公司 |
Mrna的cns递送及其用途
|
|
RS66380B1
(sr)
|
2014-04-23 |
2025-02-28 |
Modernatx Inc |
Vakcine nukleinske kiseline
|
|
MX373952B
(es)
|
2014-04-25 |
2020-07-13 |
Shire Human Genetic Therapies |
Métodos de purificación de arn mensajero.
|
|
CN106659731A
(zh)
|
2014-05-30 |
2017-05-10 |
夏尔人类遗传性治疗公司 |
用于递送核酸的可生物降解脂质
|
|
JP6599373B2
(ja)
|
2014-06-24 |
2019-10-30 |
シャイアー ヒューマン ジェネティック セラピーズ インコーポレイテッド |
核酸の送達のための立体化学的に濃縮した組成物
|
|
CN114344275A
(zh)
|
2014-07-02 |
2022-04-15 |
川斯勒佰尔公司 |
信使rna的包封
|
|
AU2015357562B2
(en)
|
2014-12-05 |
2021-10-21 |
Translate Bio, Inc. |
Messenger RNA therapy for treatment of articular disease
|
|
AU2016233135B2
(en)
|
2015-03-19 |
2021-07-08 |
Translate Bio, Inc. |
mRNA therapy for pompe disease
|
|
EP3283059B1
(en)
|
2015-04-13 |
2024-01-03 |
CureVac Manufacturing GmbH |
Method for producing rna compositions
|
|
US10626393B2
(en)
|
2015-06-04 |
2020-04-21 |
Arbutus Biopharma Corporation |
Delivering CRISPR therapeutics with lipid nanoparticles
|
|
US20180245074A1
(en)
*
|
2015-06-04 |
2018-08-30 |
Protiva Biotherapeutics, Inc. |
Treating hepatitis b virus infection using crispr
|
|
WO2017019935A1
(en)
*
|
2015-07-30 |
2017-02-02 |
Modernatx, Inc. |
Multimeric mrna
|
|
WO2017031232A1
(en)
|
2015-08-17 |
2017-02-23 |
Modernatx, Inc. |
Methods for preparing particles and related compositions
|
|
ES2910425T3
(es)
|
2015-09-17 |
2022-05-12 |
Modernatx Inc |
Compuestos y composiciones para la administración intracelular de agentes terapéuticos
|
|
CN108473969B9
(zh)
|
2015-10-14 |
2024-08-23 |
川斯勒佰尔公司 |
用于增强生产的rna相关酶的修饰
|
|
JP7011830B2
(ja)
|
2015-10-14 |
2022-01-27 |
エックス－サーマ インコーポレイテッド |
氷晶形成を低減するための組成物および方法
|
|
JP6921833B2
(ja)
|
2015-10-22 |
2021-08-18 |
モデルナティーエックス， インコーポレイテッド |
ヒトサイトメガロウイルスワクチン
|
|
EP4036079B1
(en)
|
2015-12-22 |
2025-11-19 |
ModernaTX, Inc. |
Compounds and compositions for intracellular delivery of agents
|
|
ES2844180T3
(es)
|
2016-04-08 |
2021-07-21 |
Translate Bio Inc |
Acido nucleico codificante multimérico y usos del mismo
|
|
EP3442590A2
(en)
|
2016-04-13 |
2019-02-20 |
Modernatx, Inc. |
Lipid compositions and their uses for intratumoral polynucleotide delivery
|
|
ES2985317T3
(es)
*
|
2016-05-16 |
2024-11-05 |
Univ Texas |
Composiciones para la distribución de ARNt en nanopartículas y procedimientos de uso de las mismas
|
|
AU2017283479B2
(en)
|
2016-06-13 |
2023-08-17 |
Translate Bio, Inc. |
Messenger RNA therapy for the treatment of ornithine transcarbamylase deficiency
|
|
CA3034681A1
(en)
*
|
2016-06-30 |
2018-01-04 |
Arbutus Biopharma Corporation |
Compositions and methods for delivering messenger rna
|
|
WO2018009838A1
(en)
|
2016-07-07 |
2018-01-11 |
Rubius Therapeutics, Inc. |
Compositions and methods related to therapeutic cell systems expressing exogenous rna
|
|
EP3528821A4
(en)
|
2016-10-21 |
2020-07-01 |
ModernaTX, Inc. |
HUMAN CYTOMEGALOVIRUS VACCINE
|
|
US12491261B2
(en)
|
2016-10-26 |
2025-12-09 |
Acuitas Therapeutics, Inc. |
Lipid nanoparticle formulations
|
|
EP3538067A1
(en)
|
2016-11-08 |
2019-09-18 |
Modernatx, Inc. |
Stabilized formulations of lipid nanoparticles
|
|
ES2905591T3
(es)
|
2017-01-27 |
2022-04-11 |
Methodist Hospital |
Plataforma de estructura de núcleo/cáscara para inmunoterapia
|
|
US11253605B2
(en)
|
2017-02-27 |
2022-02-22 |
Translate Bio, Inc. |
Codon-optimized CFTR MRNA
|
|
AU2018234814B2
(en)
*
|
2017-03-15 |
2022-06-30 |
Modernatx, Inc. |
Crystal forms of amino lipids
|
|
US11464848B2
(en)
|
2017-03-15 |
2022-10-11 |
Modernatx, Inc. |
Respiratory syncytial virus vaccine
|
|
WO2018170336A1
(en)
|
2017-03-15 |
2018-09-20 |
Modernatx, Inc. |
Lipid nanoparticle formulation
|
|
RS63953B1
(sr)
|
2017-03-15 |
2023-02-28 |
Modernatx Inc |
Jedinjenje i kompozicije za intracelularnu isporuku terapeutskih sredstava
|
|
MA49138A
(fr)
|
2017-05-16 |
2020-03-25 |
Translate Bio Inc |
Traitement de la fibrose kystique par administration d'arnm à codons optimisés codant pour la cftr
|
|
AU2018270111B2
(en)
|
2017-05-18 |
2022-07-14 |
Modernatx, Inc. |
Polynucleotides encoding tethered interleukin-12 (IL12) polypeptides and uses thereof
|
|
WO2018232120A1
(en)
|
2017-06-14 |
2018-12-20 |
Modernatx, Inc. |
Compounds and compositions for intracellular delivery of agents
|
|
MA49395A
(fr)
|
2017-06-14 |
2020-04-22 |
Modernatx Inc |
Polynucléotides codant pour le facteur viii de coagulation
|
|
EP3638215A4
(en)
|
2017-06-15 |
2021-03-24 |
Modernatx, Inc. |
RNA FORMULATIONS
|
|
US20190046649A1
(en)
*
|
2017-08-09 |
2019-02-14 |
University Of Maryland, Baltimore County |
Delivery device and use thereof for loading cell plasma membranes
|
|
EP4328314A3
(en)
|
2017-08-22 |
2024-03-20 |
Tessera Therapeutics, Inc. |
Lipid nanoparticle methods and compositions for producing engineered erythroid cells
|
|
CA3073211A1
(en)
|
2017-08-31 |
2019-03-07 |
Modernatx, Inc. |
Methods of making lipid nanoparticles
|
|
EP3727428A1
(en)
|
2017-12-20 |
2020-10-28 |
Translate Bio, Inc. |
Improved composition and methods for treatment of ornithine transcarbamylase deficiency
|
|
CN118634318A
(zh)
*
|
2017-12-27 |
2024-09-13 |
武田药品工业株式会社 |
含核酸脂质纳米粒子及其用途
|
|
US20190330591A1
(en)
|
2018-01-10 |
2019-10-31 |
Rubius Therapeutics, Inc. |
Amplifiable rnas for therapeutic cell systems
|
|
US11911453B2
(en)
|
2018-01-29 |
2024-02-27 |
Modernatx, Inc. |
RSV RNA vaccines
|
|
CN112930396B
(zh)
|
2018-08-24 |
2024-05-24 |
川斯勒佰尔公司 |
用于纯化信使rna的方法
|
|
EP3853202A1
(en)
|
2018-09-19 |
2021-07-28 |
ModernaTX, Inc. |
Compounds and compositions for intracellular delivery of therapeutic agents
|
|
WO2020061457A1
(en)
|
2018-09-20 |
2020-03-26 |
Modernatx, Inc. |
Preparation of lipid nanoparticles and methods of administration thereof
|
|
JP7387745B2
(ja)
*
|
2018-10-01 |
2023-11-28 |
アルニラム・ファーマシューティカルズ・インコーポレーテッド |
活性物質の送達のための生分解性脂質
|
|
WO2020077007A1
(en)
|
2018-10-09 |
2020-04-16 |
The University Of British Columbia |
Compositions and systems comprising transfection-competent vesicles free of organic-solvents and detergents and methods related thereto
|
|
BR112021007360A2
(pt)
|
2018-10-18 |
2021-07-20 |
Takeda Pharmaceutical Company Limited |
métodos para ativar/proliferar células t, para distribuir um ácido nucleico em células t e para produzir um medicamento, célula t, medicamento, cultura de células, composição, e, kit para distribuir um ácido nucleico em células t
|
|
WO2020081933A1
(en)
*
|
2018-10-19 |
2020-04-23 |
Translate Bio, Inc. |
Pumpless encapsulation of messenger rna
|
|
CN113286882A
(zh)
*
|
2018-11-09 |
2021-08-20 |
阿布特斯生物制药公司 |
脂质纳米颗粒制剂
|
|
US20220001029A1
(en)
*
|
2018-11-09 |
2022-01-06 |
Arbutus Biopharma Corporation |
Lipid nanoparticle formulations
|
|
AU2019384557B2
(en)
|
2018-11-21 |
2025-07-17 |
Translate Bio, Inc. |
Treatment of cystic fibrosis by delivery of nebulized mRNA encoding CFTR
|
|
WO2020190750A1
(en)
|
2019-03-15 |
2020-09-24 |
Modernatx, Inc. |
Hiv rna vaccines
|
|
CA3147875A1
(en)
|
2019-07-19 |
2021-01-28 |
Flagship Pioneering Innovations Vi, Llc |
Recombinase compositions and methods of use
|
|
EP4454640A3
(en)
*
|
2019-08-14 |
2025-02-12 |
Acuitas Therapeutics Inc. |
Improved lipid nanoparticles for delivery of nucleic acids
|
|
AR120080A1
(es)
|
2019-09-19 |
2022-02-02 |
Modernatx Inc |
Compuestos lipídicos de cola ramificada y composiciones para la administración intracelular de agentes terapéuticos
|
|
WO2021055849A1
(en)
*
|
2019-09-19 |
2021-03-25 |
Modernatx, Inc. |
Headgroup lipid compounds and compositions for intracellular delivery of therapeutic agents
|
|
CN114828836A
(zh)
*
|
2019-10-18 |
2022-07-29 |
宾夕法尼亚大学理事会 |
脂质和用于药物递送的脂质纳米颗粒配方
|
|
EP4048317A4
(en)
*
|
2019-10-22 |
2023-11-22 |
Genevant Sciences Gmbh |
ORNITHINE TRANS CARBAMYLASE (OTC) CONSTRUCTS AND METHODS OF USE THEREOF
|
|
WO2021188389A2
(en)
|
2020-03-17 |
2021-09-23 |
Genevant Sciences Gmbh |
Cationic lipids for lipid nanoparticle delivery of therapeutics to hepatic stellate cells
|
|
MX2022011806A
(es)
|
2020-03-24 |
2023-01-11 |
Generation Bio Co |
Vectores de adn no virales y usos de estos para expresar agentes terapéuticos contra gaucher.
|
|
IL296660A
(en)
|
2020-03-24 |
2022-11-01 |
Generation Bio Co |
Non-viral dna vectors and uses thereof for expressing factor ix therapeutics
|
|
CA3178455A1
(en)
|
2020-04-09 |
2021-10-14 |
Suzhou Abogen Biosciences Co., Ltd. |
Lipid nanoparticle composition
|
|
CN113874507A
(zh)
|
2020-04-09 |
2021-12-31 |
苏州艾博生物科技有限公司 |
冠状病毒的核酸疫苗
|
|
AU2021275223A1
(en)
|
2020-05-20 |
2023-02-02 |
Flagship Pioneering Innovations Vi, Llc. |
Coronavirus antigen compositions and their uses
|
|
US20230193311A1
(en)
|
2020-05-20 |
2023-06-22 |
Flagship Pioneering Innovations Vi, Llc |
Immunogenic compositions and uses thereof
|
|
CA3182026A1
(en)
|
2020-05-29 |
2021-12-02 |
Flagship Pioneering Innovations Vi, Llc. |
Trem compositions and methods relating thereto
|
|
EP4158031A1
(en)
|
2020-05-29 |
2023-04-05 |
Flagship Pioneering Innovations VI, LLC |
Trem compositions and methods relating thereto
|
|
KR20230030588A
(ko)
|
2020-06-30 |
2023-03-06 |
쑤저우 아보젠 바이오사이언시스 컴퍼니 리미티드 |
지질 화합물 및 지질 나노입자 조성물
|
|
KR20230051172A
(ko)
|
2020-07-16 |
2023-04-17 |
아퀴타스 테라퓨틱스 인크. |
지질 나노 입자에 사용하기 위한 양이온성 지질
|
|
AU2021329900A1
(en)
*
|
2020-08-18 |
2023-03-16 |
Ohio State Innovation Foundation |
Bioinspired lipid derivatives and uses thereof
|
|
KR20230054672A
(ko)
|
2020-08-20 |
2023-04-25 |
쑤저우 아보젠 바이오사이언시스 컴퍼니 리미티드 |
지질 화합물 및 지질 나노입자 조성물
|
|
US11406703B2
(en)
|
2020-08-25 |
2022-08-09 |
Modernatx, Inc. |
Human cytomegalovirus vaccine
|
|
JP2023542492A
(ja)
|
2020-09-03 |
2023-10-10 |
フラッグシップ パイオニアリング イノベーションズ シックス，エルエルシー |
免疫原性組成物及びその使用
|
|
MX2023004371A
(es)
|
2020-10-14 |
2023-07-26 |
George Mason Res Foundation Inc |
Lípidos ionizables, y métodos de fabricación y uso de los mismos.
|
|
TW202233232A
(zh)
|
2020-11-06 |
2022-09-01 |
法商賽諾菲公司 |
遞送mRNA疫苗的脂質奈米顆粒
|
|
PH12023500013A1
(en)
*
|
2020-12-04 |
2024-03-11 |
Tidal Therapeutics Inc |
Ionizable cationic lipids and lipi nanoparticles, and methods of synthesis and use thereof
|
|
AU2021403156A1
(en)
|
2020-12-18 |
2023-07-13 |
Genevant Sciences Gmbh |
Peg lipids and lipid nanoparticles
|
|
CA3206285A1
(en)
|
2020-12-23 |
2022-06-30 |
Flagship Pioneering, Inc. |
Compositions of modified trems and uses thereof
|
|
CN116615472A
(zh)
|
2021-01-14 |
2023-08-18 |
苏州艾博生物科技有限公司 |
聚合物缀合的脂质化合物和脂质纳米颗粒组合物
|
|
WO2022152109A2
(en)
|
2021-01-14 |
2022-07-21 |
Suzhou Abogen Biosciences Co., Ltd. |
Lipid compounds and lipid nanoparticle compositions
|
|
AU2022238571A1
(en)
|
2021-03-18 |
2023-09-14 |
Seagen Inc. |
Selective drug release from internalized conjugates of biologically active compounds
|
|
CA3214085A1
(en)
|
2021-03-31 |
2022-10-06 |
Darby Rye Schmidt |
Thanotransmission polypeptides and their use in treating cancer
|
|
IL308404A
(en)
|
2021-04-27 |
2024-01-01 |
Generation Bio Co |
Non-viral dna vectors expressing therapeutic antibodies and uses thereof
|
|
WO2022232286A1
(en)
|
2021-04-27 |
2022-11-03 |
Generation Bio Co. |
Non-viral dna vectors expressing anti-coronavirus antibodies and uses thereof
|
|
EP4352038A4
(en)
*
|
2021-05-06 |
2025-04-02 |
Arcturus Therapeutics, Inc. |
IONIZABLE CATIONIC LIPIDS FOR RNA DELIVERY
|
|
JP7664392B2
(ja)
|
2021-05-24 |
2025-04-17 |
スージョウ・アボジェン・バイオサイエンシズ・カンパニー・リミテッド |
脂質化合物及び脂質ナノ粒子組成物
|
|
WO2023009547A1
(en)
|
2021-07-26 |
2023-02-02 |
Flagship Pioneering Innovations Vi, Llc |
Trem compositions and uses thereof
|
|
IL311450A
(en)
|
2021-09-17 |
2024-05-01 |
Flagship Pioneering Innovations Vi Llc |
Compositions and methods for producing circular polyribonucleotides
|
|
AU2022358824A1
(en)
|
2021-10-08 |
2024-04-11 |
Suzhou Abogen Biosciences Co., Ltd. |
Lipid compounds and lipid nanoparticle compositions
|
|
CN116064598B
(zh)
|
2021-10-08 |
2024-03-12 |
苏州艾博生物科技有限公司 |
冠状病毒的核酸疫苗
|
|
AR127312A1
(es)
|
2021-10-08 |
2024-01-10 |
Suzhou Abogen Biosciences Co Ltd |
Compuestos lipídicos ycomposiciones de nanopartículas lipídicas
|
|
WO2023069397A1
(en)
|
2021-10-18 |
2023-04-27 |
Flagship Pioneering Innovations Vi, Llc |
Compositions and methods for purifying polyribonucleotides
|
|
EP4430024A1
(en)
|
2021-11-08 |
2024-09-18 |
Orna Therapeutics, Inc. |
Lipid nanoparticle compositions for delivering circular polynucleotides
|
|
MX2024006440A
(es)
|
2021-11-24 |
2024-08-19 |
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Composiciones inmunogenicas y sus usos.
|
|
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(en)
|
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2023-06-01 |
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Coronavirus immunogen compositions and their uses
|
|
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(en)
|
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|
|
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(ja)
|
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|
|
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(en)
|
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|
|
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(zh)
|
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|
|
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(zh)
|
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脂质化合物和脂质纳米颗粒组合物
|
|
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(zh)
*
|
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2022-04-29 |
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一种新型阳离子脂质化合物及其组合物和用途
|
|
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(en)
|
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2023-08-03 |
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Ionizable cationic lipids for lipid nanoparticles
|
|
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(en)
|
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Generation Bio Co. |
Heterologous prime boost vaccine compositions and methods of use
|
|
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(ja)
|
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新規のイオン化脂質および脂質ナノ粒子ならびにそれらを使用する方法
|
|
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(ja)
|
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ワクチン及び関連する方法
|
|
CN114685784B
(zh)
*
|
2022-04-26 |
2023-09-15 |
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|
|
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(en)
|
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2024-11-14 |
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Trem compositions and methods of use for treating proliferative disorders
|
|
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(en)
|
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Double stranded dna compositions and related methods
|
|
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(en)
|
2022-05-31 |
2022-07-13 |
Sisaf Ltd |
Therapeutic compounds and compositions
|
|
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(en)
|
2022-06-07 |
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Generation Bio Co. |
Lipid nanoparticle compositions and uses thereof
|
|
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(en)
|
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2023-12-28 |
Flagship Pioneering Innovations Vi, Llc |
Compositions of modified trems and uses thereof
|
|
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(en)
|
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2022-09-07 |
Sisaf Ltd |
Lipid formulations
|
|
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(en)
|
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2024-02-08 |
Flagship Pioneering Innovations Vii, Llc |
Immunomodulatory Proteins and Associated Methods
|
|
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(en)
|
2022-08-12 |
2024-02-15 |
Remix Therapeutics Inc. |
Methods and compositions for modulating splicing at alternative splice sites
|
|
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(en)
|
2022-08-19 |
2024-02-22 |
Generation Bio Co. |
Cleavable closed-ended dna (cedna) and methods of use thereof
|
|
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(zh)
|
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2025-07-01 |
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|
|
US20240174732A1
(en)
|
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2024-05-30 |
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|
|
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(ko)
|
2022-10-31 |
2025-07-01 |
플래그쉽 파이어니어링 이노베이션스 브이아이, 엘엘씨 |
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|
|
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(zh)
|
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2024-07-16 |
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|
|
WO2024102730A1
(en)
|
2022-11-08 |
2024-05-16 |
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Lipids and nanoparticle compositions for delivering polynucleotides
|
|
WO2024102762A1
(en)
|
2022-11-08 |
2024-05-16 |
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Lipids and lipid nanoparticle compositions for delivering polynucleotides
|
|
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(zh)
|
2022-11-08 |
2025-08-05 |
旗舰创业创新第六有限责任公司 |
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|
|
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(en)
|
2022-12-01 |
2024-06-06 |
Generation Bio Co. |
Novel polyglycerol-conjugated lipids and lipid nanoparticle compositions comprising the same
|
|
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(en)
|
2022-12-01 |
2025-10-08 |
Generation Bio Co. |
Lipid nanoparticles comprising nucleic acids, ionizable lipids, sterols, lipid anchored polymers and helper lipids, their uses
|
|
WO2024119074A1
(en)
|
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2024-06-06 |
Generation Bio Co. |
Stealth lipid nanoparticle compositions for cell targeting
|
|
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(en)
|
2022-12-01 |
2025-10-08 |
Generation Bio Co. |
Lipid nanoparticles comprising nucleic acids and lipid-anchored polymers
|
|
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(zh)
|
2022-12-09 |
2025-09-09 |
武田药品工业株式会社 |
经修饰的免疫调节剂
|
|
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(zh)
|
2022-12-14 |
2024-08-01 |
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用於將治療劑遞送至骨之組成物和方法
|
|
US20240269251A1
(en)
|
2023-01-09 |
2024-08-15 |
Flagship Pioneering Innovations V, Inc. |
Genetic switches and their use in treating cancer
|
|
US20240252520A1
(en)
|
2023-01-09 |
2024-08-01 |
Beth Israel Deaconess Medical Center, Inc. |
Therapeutic agents and their use for treating chronic wounds
|
|
WO2024151583A2
(en)
|
2023-01-09 |
2024-07-18 |
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Vaccines and related methods
|
|
WO2024151673A2
(en)
|
2023-01-09 |
2024-07-18 |
President And Fellows Of Harvard College |
Recombinant nucleic acid molecules and their use in wound healing
|
|
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(zh)
|
2023-02-06 |
2024-10-01 |
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免疫調節組合物及相關方法
|
|
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(en)
|
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2025-09-01 |
Flagship Pioneering Innovations Vii Llc |
Ionizable lipids containing degradable crosslinkers and lipid carriers for therapeutic compositions
|
|
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(en)
|
2023-02-17 |
2025-09-01 |
Flagship Pioneering Innovations Vii Llc |
DNA structures containing modified uracil
|
|
WO2024173836A2
(en)
|
2023-02-17 |
2024-08-22 |
Flagship Pioneering Innovations Vii, Llc |
Dna compositions comprising modified cytosine
|
|
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(en)
|
2023-03-15 |
2024-09-19 |
Flagship Pioneering Innovations Vi, Llc |
Immunogenic compositions and uses thereof
|
|
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(ko)
|
2023-03-15 |
2025-11-18 |
플래그쉽 파이어니어링 이노베이션스 브이아이, 엘엘씨 |
폴리리보뉴클레오티드를 포함하는 조성물 및 이의 용도
|
|
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(en)
|
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Orna Therapeutics, Inc. |
Lipids and lipid nanoparticle compositions for delivering polynucleotides
|
|
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(en)
|
2023-03-30 |
2024-10-03 |
Ose Immunotherapeutics |
Lipid-based nanoparticle targeted at activated immune cells for the expression of immune cell enhancing molecule and use thereof
|
|
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(en)
|
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2024-10-03 |
Ose Immunotherapeutics |
Method of synthesis of targeted lipid nanoparticle and uses thereof
|
|
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(zh)
|
2023-04-07 |
2024-12-16 |
日商武田藥品工業股份有限公司 |
接合複合物
|
|
WO2024216191A1
(en)
|
2023-04-12 |
2024-10-17 |
Flagship Pioneering Innovations Vi, Llc |
Modified trems, compositions, and related methods thereof
|
|
WO2024216128A1
(en)
|
2023-04-12 |
2024-10-17 |
Flagship Pioneering Innovations Vi, Llc |
Trems for use in correction of missense mutations
|
|
WO2024220746A2
(en)
|
2023-04-21 |
2024-10-24 |
Flagship Pioneering Innovations Vii, Llc |
Rnai agents targeting fatty acid synthase and related methods
|
|
WO2024233308A2
(en)
|
2023-05-05 |
2024-11-14 |
Orna Therapeutics, Inc. |
Circular rna compositions and methods
|
|
WO2024236361A1
(en)
|
2023-05-15 |
2024-11-21 |
Takeda Pharmaceutical Company Limited |
Compositions and methods for delivery of nucleic acids to cells
|
|
WO2024236504A1
(en)
|
2023-05-15 |
2024-11-21 |
Takeda Pharmaceutical Company Limited |
Sequences and methods for delivery of dna and rna
|
|
WO2024258829A1
(en)
|
2023-06-12 |
2024-12-19 |
Flagship Pioneering Innovations Vii, Llc |
Sars-cov-2 vaccine compositions and related methods
|
|
WO2025006684A1
(en)
|
2023-06-28 |
2025-01-02 |
Flagship Pioneering Innovations Vi, Llc |
Circular polyribonucleotides encoding antifusogenic polypeptides
|
|
US20250092426A1
(en)
|
2023-07-25 |
2025-03-20 |
Flagship Pioneering Innovations Vii, Llc |
Cas endonucleases and related methods
|
|
WO2025027116A1
(en)
|
2023-08-01 |
2025-02-06 |
Institut Curie |
Nanoparticles comprising nucleic acid sequences encoding cyclic gmp-amp synthase
|
|
WO2025042786A1
(en)
|
2023-08-18 |
2025-02-27 |
Flagship Pioneering Innovations Vi, Llc |
Compositions comprising circular polyribonucleotides and uses thereof
|
|
WO2025049690A1
(en)
|
2023-08-29 |
2025-03-06 |
Orna Therapeutics, Inc. |
Circular polyethylene glycol lipids
|
|
WO2025052278A1
(en)
|
2023-09-05 |
2025-03-13 |
Genevant Sciences Gmbh |
Pyrrolidine based cationic lipids for lipid nanoparticle delivery of therapeutics to hepatic stellate cells
|
|
WO2025054236A2
(en)
|
2023-09-06 |
2025-03-13 |
Flagship Pioneering Innovations Vii, Llc |
Sars-cov-2 vaccine compositions and related methods
|
|
WO2025052180A2
(en)
|
2023-09-07 |
2025-03-13 |
Axelyf ehf. |
Lipids and lipid nanoparticles
|
|
TW202525266A
(zh)
|
2023-09-18 |
2025-07-01 |
美商旗艦先鋒創新有限責任（Ｖｉｉ）公司 |
可電離類脂質組成物及其治療用途
|
|
WO2025072331A1
(en)
|
2023-09-26 |
2025-04-03 |
Flagship Pioneering Innovations Vii, Llc |
Cas nucleases and related methods
|
|
WO2025096807A2
(en)
|
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2025-05-08 |
Flagship Pioneering Innovations Vii, Llc |
Novel therapeutic dna forms
|
|
WO2025101501A1
(en)
|
2023-11-07 |
2025-05-15 |
Orna Therapeutics, Inc. |
Circular rna compositions
|
|
WO2025106670A1
(en)
|
2023-11-14 |
2025-05-22 |
Flagship Pioneering Innovations Vii, Llc |
Ionizable lipidoid compositions and therapeutic uses thereof
|
|
US20250161347A1
(en)
|
2023-11-22 |
2025-05-22 |
Flagship Pioneering Innovations Vii, Llc |
Methods and compositions for treating non-alcoholic fatty liver disease
|
|
WO2025117877A2
(en)
|
2023-12-01 |
2025-06-05 |
Flagship Pioneering Innovations Vii, Llc |
Cas nucleases and related methods
|
|
WO2025133115A1
(en)
|
2023-12-21 |
2025-06-26 |
Ose Immunotherapeutics |
Lipid-based nanoparticles comprising il-35
|
|
WO2025160334A1
(en)
|
2024-01-26 |
2025-07-31 |
Flagship Pioneering Innovations Vii, Llc |
Immunoreceptor inhibitory proteins and related methods
|
|
WO2025157978A1
(en)
*
|
2024-01-26 |
2025-07-31 |
Merck Patent Gmbh |
Ionizable lipids for use in lipid nanoparticles
|
|
WO2025194138A1
(en)
|
2024-03-14 |
2025-09-18 |
Tessera Therapeutics, Inc. |
St1cas9 compositions and methods for modulating a genome
|
|
WO2025194019A1
(en)
|
2024-03-14 |
2025-09-18 |
Flagship Pioneering Innovations Vii, Llc |
Methods for treating liver fibrosis and non-alcoholic fatty liver disease
|
|
WO2025217275A2
(en)
|
2024-04-10 |
2025-10-16 |
Flagship Pioneering Innovations Vii, Llc |
Immune cell targeted compositions and related methods
|
|
US20250353881A1
(en)
|
2024-05-16 |
2025-11-20 |
Flagship Pioneering Innovations Vii, Llc |
Immunoreceptor inhibitory proteins and related methods
|
|
WO2025245188A2
(en)
|
2024-05-21 |
2025-11-27 |
Flagship Pioneering Innovations Vii, Llc |
Methods of treating liver steatosis and non-alcoholic fatty liver disease
|
|
WO2025245111A1
(en)
|
2024-05-22 |
2025-11-27 |
Flagship Pioneering Innovations Vii, Llc |
Immunoreceptor targeting proteins and related methods
|