JP2016521683A5 - - Google Patents

Download PDF

Info

Publication number
JP2016521683A5
JP2016521683A5 JP2016514523A JP2016514523A JP2016521683A5 JP 2016521683 A5 JP2016521683 A5 JP 2016521683A5 JP 2016514523 A JP2016514523 A JP 2016514523A JP 2016514523 A JP2016514523 A JP 2016514523A JP 2016521683 A5 JP2016521683 A5 JP 2016521683A5
Authority
JP
Japan
Prior art keywords
antibody
group
fragment
hydroxytryptophan
acetic acid
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP2016514523A
Other languages
English (en)
Japanese (ja)
Other versions
JP2016521683A (ja
Filing date
Publication date
Application filed filed Critical
Priority claimed from PCT/IB2014/061634 external-priority patent/WO2014188377A2/en
Publication of JP2016521683A publication Critical patent/JP2016521683A/ja
Publication of JP2016521683A5 publication Critical patent/JP2016521683A5/ja
Pending legal-status Critical Current

Links

JP2016514523A 2013-05-24 2014-05-22 過敏性腸症候群の診断を予測するための経路特異的なアッセイ Pending JP2016521683A (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201361827506P 2013-05-24 2013-05-24
US61/827,506 2013-05-24
PCT/IB2014/061634 WO2014188377A2 (en) 2013-05-24 2014-05-22 Pathway specific assays for predicting irritable bowel syndrome diagnosis

Related Child Applications (1)

Application Number Title Priority Date Filing Date
JP2019075081A Division JP2019151637A (ja) 2013-05-24 2019-04-10 過敏性腸症候群の診断を予測するための経路特異的なアッセイ

Publications (2)

Publication Number Publication Date
JP2016521683A JP2016521683A (ja) 2016-07-25
JP2016521683A5 true JP2016521683A5 (https=) 2017-06-29

Family

ID=50884973

Family Applications (4)

Application Number Title Priority Date Filing Date
JP2016514524A Pending JP2016520199A (ja) 2013-05-24 2014-05-22 過敏性腸症候群を診断するための経路特異的マーカー
JP2016514523A Pending JP2016521683A (ja) 2013-05-24 2014-05-22 過敏性腸症候群の診断を予測するための経路特異的なアッセイ
JP2019075081A Pending JP2019151637A (ja) 2013-05-24 2019-04-10 過敏性腸症候群の診断を予測するための経路特異的なアッセイ
JP2019104805A Pending JP2019194600A (ja) 2013-05-24 2019-06-04 過敏性腸症候群を診断するための経路特異的マーカー

Family Applications Before (1)

Application Number Title Priority Date Filing Date
JP2016514524A Pending JP2016520199A (ja) 2013-05-24 2014-05-22 過敏性腸症候群を診断するための経路特異的マーカー

Family Applications After (2)

Application Number Title Priority Date Filing Date
JP2019075081A Pending JP2019151637A (ja) 2013-05-24 2019-04-10 過敏性腸症候群の診断を予測するための経路特異的なアッセイ
JP2019104805A Pending JP2019194600A (ja) 2013-05-24 2019-06-04 過敏性腸症候群を診断するための経路特異的マーカー

Country Status (14)

Country Link
US (5) US9891235B2 (https=)
EP (2) EP3004892B1 (https=)
JP (4) JP2016520199A (https=)
KR (2) KR20160010621A (https=)
CN (2) CN105579852B (https=)
AU (3) AU2014269961A1 (https=)
BR (2) BR112015029318A2 (https=)
CA (2) CA2913108A1 (https=)
HK (1) HK1223361A1 (https=)
IL (2) IL242595B (https=)
MX (1) MX367046B (https=)
RU (2) RU2015155552A (https=)
SG (2) SG11201509371XA (https=)
WO (2) WO2014188377A2 (https=)

Families Citing this family (65)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SG11201509371XA (en) * 2013-05-24 2015-12-30 Nestec Sa Pathway specific markers for diagnosing irritable bowel syndrome
AU2014284047B2 (en) 2013-06-21 2018-11-22 Ondek Pty Ltd Immunotherapy composition and use thereof
AU2015257589A1 (en) * 2014-05-09 2016-11-24 Nogra Pharma Limited Methods for treating inflammatory bowel disease
KR102546748B1 (ko) 2014-11-19 2023-06-22 엔제트피 유케이 리미티드 스테로이드 FXR 조절인자를 제조하기 위한 중간체로서의 6α-알킬-3,7-다이온 스테로이드
CN107207559B (zh) 2014-11-19 2019-10-25 Nzp英国有限公司 作为制备类固醇fxr调节剂的中间体的6-烷基-7-羟基-4-烯-3-酮类固醇
SG11201703729RA (en) 2014-11-19 2017-06-29 Nestec Sa Antibodies against serotonin, tryptophan and kynurenine metabolites and uses thereof
EA033445B1 (ru) 2014-11-19 2019-10-31 Nzp Uk Ltd 5-бета-6-алкил-7-гидрокси-3-оновые стероиды в качестве промежуточных соединений для получения стероидных модуляторов fxr
KR102527821B1 (ko) 2014-11-19 2023-05-02 엔제트피 유케이 리미티드 스테로이드 FXR 조절인자를 제조하기 위한 중간체로서의 6α-알킬-6,7-다이온 스테로이드
CA2969326A1 (en) * 2014-12-02 2016-06-09 Nestec S.A. Methods for establishing a vedolizumab dosing regimen to treat patients with irritable bowel disease
CN105987995A (zh) * 2015-02-04 2016-10-05 东莞博捷生物科技有限公司 一种检测人抗酿酒酵母IgG类抗体的酶联免疫试剂盒
CN105987996A (zh) * 2015-02-09 2016-10-05 东莞博捷生物科技有限公司 一种检测人抗酿酒酵母IgA类抗体的酶联免疫试剂盒
CN105061305A (zh) * 2015-08-31 2015-11-18 河南师范大学 一步合成3-甲基-2-吡啶甲酸甲酯的方法
GB201608777D0 (en) 2016-05-18 2016-06-29 Dextra Lab Ltd Compounds
CN106399344B (zh) * 2016-06-01 2021-01-01 上海领潮生物新材料有限公司 一种vin-cdtb融合蛋白的制备方法
WO2018011691A1 (en) * 2016-07-12 2018-01-18 Nestec S.A. Competitive immunoassay methods
CN106188191A (zh) * 2016-07-13 2016-12-07 西安电子科技大学 基于gsh响应的诊治一体化有机分子探针及其制备方法
CA3036702A1 (en) * 2016-09-15 2018-03-22 Sun Genomics Inc. Universal method for extracting nucleic acid molecules from a diverse population of one or more types of microbes in a sample
US10428370B2 (en) 2016-09-15 2019-10-01 Sun Genomics, Inc. Universal method for extracting nucleic acid molecules from a diverse population of one or more types of microbes in a sample
US11959125B2 (en) 2016-09-15 2024-04-16 Sun Genomics, Inc. Universal method for extracting nucleic acid molecules from a diverse population of one or more types of microbes in a sample
US10610104B2 (en) 2016-12-07 2020-04-07 Progenity, Inc. Gastrointestinal tract detection methods, devices and systems
EP3554346B1 (en) 2016-12-14 2024-01-31 Biora Therapeutics, Inc. Treatment of a disease of the gastrointestinal tract with an immunosuppressant
WO2018112232A1 (en) 2016-12-14 2018-06-21 Progenity Inc. Treatment of a disease of the gastrointestinal tract with an il-12/il-23 inhibitor released using an ingestible device
BR112019012071A2 (pt) 2016-12-14 2019-11-12 Progenity Inc tratamento de uma doença do trato gastrointestinal com um inibidor de integrina
CA3045310A1 (en) 2016-12-14 2018-06-21 Progenity, Inc. Treatment of a disease of the gastrointestinal tract with a chemokine/chemokine receptor inhibitor
EP3554342B1 (en) 2016-12-14 2024-07-24 Biora Therapeutics, Inc. Treatment of a disease of the gastrointestinal tract with a tnf inhibitor
WO2018112256A1 (en) 2016-12-14 2018-06-21 Progenity Inc. Treatment of a disease of the gastrointestinal tract with an il-1 inhibitor
EP3554485B9 (en) 2016-12-14 2023-09-27 Biora Therapeutics, Inc. Treatment of a disease of the gastrointestinal tract with a jak inhibitor and devices
US11978543B2 (en) 2016-12-14 2024-05-07 Astarte Medical Partners Inc. System and methods for developing and using a microbiome-based action component
US11134889B2 (en) 2016-12-14 2021-10-05 Progenity, Inc. Treatment of a disease of the gastrointestinal tract with a SMAD7 inhibitor
EP3554362A4 (en) * 2016-12-14 2020-08-12 Warren, Tracy SYSTEM AND METHODS FOR DEVELOPING AND USING A MICROBIOME-BASED ACTION COMPONENT FOR PATIENT HEALTH
WO2018112237A1 (en) 2016-12-14 2018-06-21 Progenity Inc. Treatment of a disease of the gastrointestinal tract with an il-6r inhibitor
CA3046019A1 (en) 2016-12-14 2018-06-21 Progenity Inc. Treatment of a disease of the gastrointestinal tract with a tlr modulator
AU2018244922A1 (en) 2017-03-30 2019-09-12 Biora Therapeutics, Inc. Treatment of a disease of the gastrointestinal tract with live biotherapeutics
EP3600414A1 (en) 2017-03-30 2020-02-05 Progenity Inc. Treatment of a disease of the gastrointestinal tract with il-10 or an il-10 agonist
WO2018183932A1 (en) 2017-03-30 2018-10-04 Progenity Inc. Treatment of a disease of the gastrointestinal tract with a il-13 inhibitor
US20210138213A1 (en) 2017-03-30 2021-05-13 Progenity, Inc. Treatment of a disease of the gastrointestinal tract with an immune modulatory agent released using an ingestible device
EP3600249A1 (en) 2017-03-30 2020-02-05 Progenity Inc. Treatment of a disease of the gastrointestinal tract with a chst15 inhibitor
US20200306516A1 (en) 2017-08-14 2020-10-01 Progenity, Inc. Treatment of a disease of the gastrointestinal tract with glatiramer or a pharmaceutically acceptable salt thereof
US12582809B2 (en) 2018-01-26 2026-03-24 Bt Bidco, Inc. Treatment of a disease of the gastrointestinal tract with a PDE4 inhibitor
ES3056147T3 (en) * 2018-02-09 2026-02-18 Metabolomic Diagnostics Ltd A system and method of generating a model to detect, or predict the risk of, an outcome
WO2019181830A1 (ja) * 2018-03-19 2019-09-26 富士フイルム和光純薬株式会社 精神疾患の判定方法
US12461111B2 (en) * 2018-04-24 2025-11-04 Universiteit Gent Intestinal and fecal biomarkers for intestinal health of poultry
AU2019278927A1 (en) 2018-06-01 2020-12-24 Bt Bidco, Inc. Devices and systems for gastrointestinal microbiome detection and manipulation
KR20210018823A (ko) * 2018-06-07 2021-02-18 4디 파마 피엘씨 Ibs 환자 계층화 방법
CN110607335B (zh) * 2018-06-14 2021-08-03 中国科学院微生物研究所 一种烟酰胺腺嘌呤二核苷酸类化合物生物合成方法
CN109324132A (zh) * 2018-10-31 2019-02-12 杭州佰辰医学检验所有限公司 高通量检测色氨酸及其代谢产物的试剂盒及其应用
US11488699B1 (en) 2018-12-09 2022-11-01 Cerner Innovation, Inc. Microbiota activity sensor and decision support tool
US11842795B1 (en) * 2018-12-17 2023-12-12 Cerner Innovation, Inc. Irritable bowel syndrome diagnostic sensor and decision support tool
FR3094492A1 (fr) * 2019-04-01 2020-10-02 Polyneuros Procédé de détection ou de suivi de l’évolution d’une maladie chronique dégénérative par dosage immunologique
CN114127317A (zh) * 2019-04-03 2022-03-01 4D制药科克有限公司 诊断疾病的方法
WO2020213732A1 (ja) * 2019-04-18 2020-10-22 株式会社サイキンソー 過敏性腸症候群の検査方法
US11884958B2 (en) * 2019-04-30 2024-01-30 Mayo Foundation For Medical Education And Research Assessing and treating functional gastrointestinal disorders
JP2022533956A (ja) 2019-05-14 2022-07-27 プロメテウス バイオサイエンシーズ,インク. Tl1a患者を選択する方法、システム、およびデバイス
WO2020232262A1 (en) * 2019-05-16 2020-11-19 Procisedx Inc. Assay detection methods for vcam-1 and calprotectin
CN111351870A (zh) * 2019-12-03 2020-06-30 康美华大基因技术有限公司 一种肠易激综合征血清代谢标记物组合及其诊断试剂盒
US20230074127A1 (en) 2020-01-27 2023-03-09 Immundiagnostik Ag Test and in vitro diagnosis of irritable bowel syndrome
WO2021152586A1 (en) * 2020-01-30 2021-08-05 Yeda Research And Development Co. Ltd. Methods of analyzing microbiome, immunoglobulin profile and physiological state
EP3913371A1 (en) 2020-05-18 2021-11-24 Neuroimmun GmbH Method and kit for diagnosting irritable bowel syndrome and for its relief through dietary interventions
KR102478205B1 (ko) * 2020-09-24 2022-12-15 경희대학교 산학협력단 크론병 환자에서 상부위장관 침범 진단을 위한 정보 제공 방법
CN114755313B (zh) * 2021-01-08 2024-08-30 复旦大学附属华山医院 包含尿液nad+代谢物的急性肾损伤标志物
CN115724779B (zh) * 2021-09-01 2024-03-29 四川大学 酰胺烷二硫化合物、其制备方法和用途
EP4452939A4 (en) * 2021-12-24 2025-12-10 Kuleon Llc SEROTONINERGIC COMPOUNDS, POLYPODS, AND PROMEDICINAL PRODIGITS OF SEROTONIN RECEPTOR AGONISTS AND ANTAGONISTS
WO2023180899A1 (en) * 2022-03-21 2023-09-28 Swain Manish Kumar Device and method for detecting diarrhea
CN116381222A (zh) * 2023-03-23 2023-07-04 北京巴瑞医疗器械有限公司 一种血清素发光免疫检测方法及血清素检测试剂盒
CN116990498B (zh) * 2023-09-28 2024-08-09 山东大学齐鲁医院 血浆色氨酸代谢物在儿童偏头痛诊断中的应用

Family Cites Families (33)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4816567A (en) 1983-04-08 1989-03-28 Genentech, Inc. Recombinant immunoglobin preparations
US4676980A (en) 1985-09-23 1987-06-30 The United States Of America As Represented By The Secretary Of The Department Of Health And Human Services Target specific cross-linked heteroantibodies
US5571894A (en) 1991-02-05 1996-11-05 Ciba-Geigy Corporation Recombinant antibodies specific for a growth factor receptor
FI941572L (fi) 1991-10-07 1994-05-27 Oncologix Inc Anti-erbB-2-monoklonaalisten vasta-aineiden yhdistelmä ja käyttömenetelmä
WO1993008829A1 (en) 1991-11-04 1993-05-13 The Regents Of The University Of California Compositions that mediate killing of hiv-infected cells
AU675929B2 (en) 1992-02-06 1997-02-27 Curis, Inc. Biosynthetic binding protein for cancer marker
EP0656064B1 (en) 1992-08-17 1997-03-05 Genentech, Inc. Bispecific immunoadhesins
US5731168A (en) 1995-03-01 1998-03-24 Genentech, Inc. Method for making heteromultimeric polypeptides
US5641870A (en) 1995-04-20 1997-06-24 Genentech, Inc. Low pH hydrophobic interaction chromatography for antibody purification
US6218129B1 (en) * 1998-05-15 2001-04-17 Prometheus Laboratories, Inc. Inflammatory bowel disease first step assay system
US6406862B1 (en) 1998-10-06 2002-06-18 The United States Of America As Represented By The Secretary Of The Army Dip-stick assay for C-reactive protein
AU784812B2 (en) * 1999-12-15 2006-06-29 Merck Sharp & Dohme Corp. Lipopeptides as antibacterial agents
US6838250B2 (en) 2000-03-31 2005-01-04 Ortho-Clinical Diagnostics, Inc. Immunoassay for C-reactive protein
DE10121217A1 (de) * 2001-04-30 2002-10-31 Merck Patent Gmbh 6H-Oxazolo[4,5-e]indol-Derivate als nikotinische Acetylcholinrezeptor Liganden und/oder serotonerge Liganden
CA2549971A1 (en) 2003-11-03 2005-05-12 Duke University Methods of identifying individuals at risk of perioperative bleeding, renal dysfunction or stroke
US20060154276A1 (en) * 2004-05-13 2006-07-13 Prometheus Laboratories Inc. Methods of diagnosing inflammatory bowel disease
WO2006012472A1 (en) 2004-07-21 2006-02-02 Qualyst, Inc. Apparatus, kits and methods for evaluating binding interactions, for detecting and quantifying binding molecules, and for sample preparation
WO2007000046A1 (en) * 2005-06-27 2007-01-04 Holburn Biomedical Corporation Methods for diagnosing functional bowel disease
US7873479B2 (en) 2005-12-01 2011-01-18 Prometheus Laboratories Inc. Methods of diagnosing inflammatory bowel disease
US20100094560A1 (en) 2006-08-15 2010-04-15 Prometheus Laboratories Inc. Methods for diagnosing irritable bowel syndrome
US20080085524A1 (en) 2006-08-15 2008-04-10 Prometheus Laboratories Inc. Methods for diagnosing irritable bowel syndrome
US8278057B2 (en) 2007-09-14 2012-10-02 Nestec S.A. Addressable antibody arrays and methods of use
CA2758531C (en) 2009-04-14 2018-11-13 Derren Barken Inflammatory bowel disease prognostics
US20120171672A1 (en) 2009-04-14 2012-07-05 Prometheus Laboratories Inc. Inflammatory bowel disease prognostics
WO2010151699A1 (en) 2009-06-25 2010-12-29 Prometheus Laboratories Inc. Methods for diagnosing irritable bowel syndrome
PH12012500850A1 (en) * 2009-10-30 2013-01-07 Prometheus Laboratories Inc Methods for diagnosing irritable bowel syndrome
BR112012012513A2 (pt) * 2009-11-25 2017-01-10 Prometheus Lab Inc método para diagnosticar síndrome do intestino irritável em um paciente, método para monitorar a progressão ou regressão da síndrome do intestino irritável em um paciente, e para designar uma terapia contra síndrome do intestino irritável a um paciente em necessidade do mesmo
US8445215B1 (en) * 2010-07-23 2013-05-21 Nestec S.A. Assays and methods for the detection of Crohn's disease
EP2710383B1 (en) * 2011-05-16 2017-01-11 The University of Newcastle Performance of a biomarker panel for irritable bowel syndrome
SG11201401536QA (en) * 2011-10-21 2014-05-29 Nestec Sa Methods for improving inflammatory bowel disease diagnosis
CA2886991A1 (en) * 2012-10-05 2014-04-10 Nestec S.A. Antibodies to microbiome, stress factors and mast cell markers as diagnostic markers for ibs
SG11201509371XA (en) * 2013-05-24 2015-12-30 Nestec Sa Pathway specific markers for diagnosing irritable bowel syndrome
TWI853985B (zh) * 2013-12-04 2024-09-01 日商中外製藥股份有限公司 因應化合物濃度使抗原結合能力變化的抗原結合分子及其資料庫

Similar Documents

Publication Publication Date Title
JP2016521683A5 (https=)
RU2015155552A (ru) Путеспецифические способы прогнозирования диагноза синдрома раздраженного кишечника
JP2017524725A5 (https=)
JP2021502063A5 (https=)
ES2581627T3 (es) Anticuerpos frente a variante truncada CTF-611 de HER2
JP2018515474A5 (https=)
JP2016511254A5 (https=)
AR080291A1 (es) Anticuerpos antagonistas anti receptor de il-7 y procedimientos
JP2019523651A5 (https=)
EA201490677A1 (ru) Связывающие антиген cd27l белки
WO2012059598A3 (en) Methods of treating rheumatoid arthritis using il-17 antagonists
EA201001139A1 (ru) УЛУЧШЕННЫЕ АНТИТЕЛА АНТИ-TrkB
CY1118829T1 (el) Ανασταλτικος vegf σταθερων και διαλυτων αντισωματων
JP2017505622A5 (https=)
EA201692192A1 (ru) СВЯЗЫВАЮЩЕЕСЯ С FcRn АНТИТЕЛО ДЛЯ ЛЕЧЕНИЯ АУТОИММУННЫХ ЗАБОЛЕВАНИЙ
JP2016516400A5 (https=)
JP2016536330A5 (https=)
JP2017532005A5 (https=)
JP2012019790A5 (https=)
JP2021511830A5 (https=)
IL186948A0 (en) Monoclonal antibodies and methods for their use in the detection of cervical disease
JP2014113150A5 (https=)
EA201270491A1 (ru) Антитела, специфически связывающие рецептор ерна2
JP2015531768A5 (https=)
JP2017512838A5 (https=)