JP2016520803A5 - - Google Patents
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- JP2016520803A5 JP2016520803A5 JP2016502475A JP2016502475A JP2016520803A5 JP 2016520803 A5 JP2016520803 A5 JP 2016520803A5 JP 2016502475 A JP2016502475 A JP 2016502475A JP 2016502475 A JP2016502475 A JP 2016502475A JP 2016520803 A5 JP2016520803 A5 JP 2016520803A5
- Authority
- JP
- Japan
- Prior art keywords
- mirna
- cancer
- level
- subject
- sample
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
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Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201361791301P | 2013-03-15 | 2013-03-15 | |
| US61/791,301 | 2013-03-15 | ||
| PCT/US2014/027541 WO2014152622A1 (en) | 2013-03-15 | 2014-03-14 | Mirna biogenesis in exosomes for diagnosis and therapy |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2018108450A Division JP6807351B2 (ja) | 2013-03-15 | 2018-06-06 | 診断及び治療のためのエクソソームにおけるmiRNAバイオジェネシス |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2016520803A JP2016520803A (ja) | 2016-07-14 |
| JP2016520803A5 true JP2016520803A5 (https=) | 2017-04-13 |
| JP6554458B2 JP6554458B2 (ja) | 2019-07-31 |
Family
ID=51581257
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2016502475A Expired - Fee Related JP6554458B2 (ja) | 2013-03-15 | 2014-03-14 | 診断及び治療のためのエクソソームにおけるmiRNAバイオジェネシス |
| JP2018108450A Active JP6807351B2 (ja) | 2013-03-15 | 2018-06-06 | 診断及び治療のためのエクソソームにおけるmiRNAバイオジェネシス |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2018108450A Active JP6807351B2 (ja) | 2013-03-15 | 2018-06-06 | 診断及び治療のためのエクソソームにおけるmiRNAバイオジェネシス |
Country Status (15)
| Country | Link |
|---|---|
| US (2) | US20160024503A1 (https=) |
| EP (2) | EP2971162B1 (https=) |
| JP (2) | JP6554458B2 (https=) |
| KR (1) | KR102183406B1 (https=) |
| CN (2) | CN105264092B (https=) |
| AU (2) | AU2014239309B2 (https=) |
| BR (1) | BR112015023275B1 (https=) |
| CA (2) | CA2905081C (https=) |
| ES (1) | ES2966571T3 (https=) |
| HK (1) | HK1218143A1 (https=) |
| IL (2) | IL241409B (https=) |
| MX (2) | MX373957B (https=) |
| PT (1) | PT3527670T (https=) |
| RU (2) | RU2018101152A (https=) |
| WO (1) | WO2014152622A1 (https=) |
Families Citing this family (40)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2016150475A1 (en) * | 2015-03-22 | 2016-09-29 | Universite De Liege | Circulating micrornas for the diagnosis of breast cancer |
| CN104774966B (zh) * | 2015-05-01 | 2017-07-28 | 北京博奥医学检验所有限公司 | 肺腺癌miRNA标记物 |
| EP3307890A1 (en) | 2015-06-10 | 2018-04-18 | Board of Regents, The University of Texas System | Use of exosomes for the treatment of disease |
| CN107151661A (zh) * | 2016-03-02 | 2017-09-12 | 上海润腾生物科技有限公司 | 一种人外泌体蛋白、试剂盒及其应用 |
| CN106202984B (zh) * | 2016-08-26 | 2018-09-04 | 赵毅 | 一种基于多层复杂网络对肿瘤miRNA标志物的筛选方法 |
| WO2018071806A1 (en) * | 2016-10-13 | 2018-04-19 | University Of Louisville Research Foundation, Inc. | Exosomal biomarkers for diagnosis and prognosis of cancer and related methods |
| US11783918B2 (en) | 2016-11-30 | 2023-10-10 | Microsoft Technology Licensing, Llc | DNA random access storage system via ligation |
| US10793897B2 (en) * | 2017-02-08 | 2020-10-06 | Microsoft Technology Licensing, Llc | Primer and payload design for retrieval of stored polynucleotides |
| CA3083140A1 (en) * | 2017-11-30 | 2019-06-06 | Provincial Health Services Authority | Methods for evaluating head and neck cancers |
| EP3775258A4 (en) | 2018-03-28 | 2022-01-26 | Board of Regents, The University of Texas System | IDENTIFICATION OF EPIGENETIC ALTERATIONS IN DNA ISOLATED FROM EXOSOMES |
| US11648260B2 (en) | 2018-03-29 | 2023-05-16 | Technion Research And Development Foundation Limitted | Vesicles comprising a PTEN inhibitor and uses of same |
| US11364280B2 (en) * | 2018-04-17 | 2022-06-21 | Taipei Veterans General Hospital | Method for blocking stress-induced tumor progression |
| CA3098105A1 (en) | 2018-04-25 | 2019-10-31 | Toray Industries, Inc. | Kit, device, and method for detecting bladder cancer |
| JP7710849B2 (ja) | 2018-10-17 | 2025-07-22 | 合同会社H.U.グループ中央研究所 | 細胞外小胞の回収方法 |
| US11766484B2 (en) | 2019-01-03 | 2023-09-26 | International Business Machines Corporation | Exosome vessels for delivery of molecular cargo |
| US20220136011A1 (en) | 2019-02-08 | 2022-05-05 | Board Of Regents, The University Of Texas System | Telomerase-containing exosomes for treatment of diseases associated with aging and age-related organ dysfunction |
| WO2020163553A1 (en) * | 2019-02-08 | 2020-08-13 | Virginia Commonwealth University | Mda-7/il-24 for cancer treatment and methods of monitoring same |
| CN118512469A (zh) * | 2019-02-26 | 2024-08-20 | 首尔大学校产学协力团 | 包含末端尿苷酰基转移酶4/7表达调控因子的用于预防或治疗癌症的药学组合物 |
| AU2020299633B2 (en) * | 2019-07-02 | 2026-03-26 | Ohio State Innovation Foundation | Neurodegenerative disease therapies utilizing the skin-brain axis |
| US20220275455A1 (en) * | 2019-07-08 | 2022-09-01 | Preferred Networks, Inc. | Data processing and classification for determining a likelihood score for breast disease |
| CN110358835A (zh) * | 2019-07-26 | 2019-10-22 | 泗水县人民医院 | 生物标志物在胃癌检测、诊断中的应用 |
| KR102212699B1 (ko) * | 2019-08-12 | 2021-02-05 | 한국원자력의학원 | 유방암 예방 또는 치료용 조성물 |
| CN110607361A (zh) * | 2019-10-08 | 2019-12-24 | 南京市儿童医院 | miR-431作为靶点在制备促进SP表达的药物中的应用 |
| US20230051797A1 (en) | 2019-12-23 | 2023-02-16 | Fujirebio Inc. | Method for recovering extracellular vesicle and blood collection vessel |
| EP3862442A3 (en) * | 2020-02-04 | 2021-10-27 | Artemisia S.p.A. | Method for the early diagnosis of cancer by means of ddpcr analysis of mirna in liquid biopsy |
| EP3862441A3 (en) * | 2020-02-04 | 2021-10-27 | Artemisia S.p.A. | Method for the early diagnosis of cancer by means of ddpcr analysis of mirna and protein markers in liquid biopsy |
| KR102318328B1 (ko) * | 2020-04-13 | 2021-10-27 | 고려대학교 산학협력단 | Gcc2 단백질을 과발현하는 엑소좀 기반 암 진단 또는 예후 예측용 마커 조성물 |
| US20230227916A1 (en) | 2020-04-15 | 2023-07-20 | H.U. Group Research Institute G.K. | Method for recovering extracellular vesicle |
| CN111920961B (zh) * | 2020-08-14 | 2023-09-08 | 福建医科大学附属协和医院 | 一种治疗癌症的药物 |
| KR102497196B1 (ko) | 2020-09-08 | 2023-02-07 | (주)유로테크 | 전립선암 진단 점수 계산 방법 및 그 용도 |
| EP4212632A4 (en) * | 2020-09-08 | 2024-07-17 | Urotech. Co., Ltd. | METHODS FOR CALCULATION OF THE DIAGNOSTIC PROSTATE CANCER SCORE AND USES THEREOF |
| WO2022102246A1 (ja) * | 2020-11-11 | 2022-05-19 | 国立研究開発法人物質・材料研究機構 | 細胞で産生された膜小胞に由来する塩基配列を解析する方法、その装置、及び、そのプログラム |
| CN112662752B (zh) * | 2021-01-18 | 2022-08-23 | 中国农业大学 | 一种诊断用生物标志物的应用 |
| KR102310302B1 (ko) * | 2021-02-08 | 2021-10-06 | 을지대학교 산학협력단 | 엑소좀 기반 방광암 진단을 위한 정보 제공 방법 |
| CN112760381B (zh) * | 2021-02-08 | 2022-11-01 | 复旦大学附属中山医院 | 一种检测肺腺癌预后的miRNA试剂盒 |
| CN117802235B (zh) * | 2022-09-30 | 2025-08-19 | 上海思路迪生物医学科技有限公司 | 血液胞外囊泡miRNA在卵巢癌诊断中的应用 |
| CN116121377A (zh) * | 2022-11-01 | 2023-05-16 | 山西医科大学 | 一种食管鳞癌外泌体富含的miRNA作为诊断食管鳞癌的标志物中的应用 |
| CN117778574B (zh) * | 2023-12-25 | 2024-09-03 | 山东中医药大学 | Mir937基因组拷贝数扩增在卵巢癌诊断和/或治疗中的应用 |
| CN118421798B (zh) * | 2024-05-22 | 2025-02-07 | 南通市海门区人民医院 | 用于检测结直肠癌相关血清生物标志物、sers传感器及制备方法 |
| EP4667011A1 (en) * | 2024-06-17 | 2025-12-24 | Bios-Therapy, Physiological Systems for Health S.p.A. | Epigenau/11: a natural matrix with therapeutic activity |
Family Cites Families (20)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20030064949A1 (en) | 1998-02-17 | 2003-04-03 | Loretta Nielsen | Combined tumor suppressor gene therapy and chemotherapy in the treatment of neoplasms |
| FR2766205B1 (fr) | 1997-07-16 | 2002-08-30 | Inst Nat Sante Rech Med | Nouveau procede de sensibilisation de cellules presentatrices d'antigene et nouveaux moyens pour la mise en oeuvre du procede |
| KR100519384B1 (ko) | 2002-08-13 | 2005-10-06 | (주)누백스 | 유전자 이입을 이용한 엑소좀의 제조방법 및 상기 엑소좀의 용도 |
| CN1281279C (zh) * | 2004-09-16 | 2006-10-25 | 浙江大学 | 针对表皮生长因子基因的小干扰核糖核酸分子及其用途 |
| CA2676113C (en) * | 2007-07-25 | 2014-07-08 | University Of Louisville Research Foundation, Inc. | Exosome-associated microrna as a diagnostic marker |
| EP2610342B1 (en) * | 2007-09-14 | 2016-05-04 | The Ohio State University Research Foundation | MiRNA Expression in Human Peripheral Blood Microvesicles and uses Thereof |
| CN106310293A (zh) * | 2007-09-27 | 2017-01-11 | 免疫疫苗技术有限公司 | 在包括连续疏水相的载体中的脂质体在体内输送多核苷酸中的应用 |
| KR101810799B1 (ko) | 2008-02-01 | 2017-12-19 | 더 제너럴 하스피탈 코포레이션 | 의학적 질환 및 병태의 진단, 예후, 및 치료에 있어서 미세소포체의 용도 |
| CN102027129B (zh) * | 2008-02-28 | 2014-03-12 | 俄亥俄州立大学研究基金会 | 用于前列腺相关病症的诊断、预后和治疗的基于微rna的方法和组合物 |
| WO2009126563A1 (en) * | 2008-04-11 | 2009-10-15 | The University Of North Carolina At Chapel Hill | Methods and compositions for the regulation of microrna processing |
| WO2009147519A1 (en) * | 2008-06-06 | 2009-12-10 | Centre National De La Recherche Scientifique - Cnrs- | Use of endo-lysosomal system and secreted vesicles (exosome-like) in treatments and diagnostics based on small rna and experimental study of small rna |
| WO2010056337A2 (en) * | 2008-11-12 | 2010-05-20 | Caris Mpi, Inc. | Methods and systems of using exosomes for determining phenotypes |
| JP2013526852A (ja) * | 2010-04-06 | 2013-06-27 | カリス ライフ サイエンシズ ルクセンブルク ホールディングス | 疾患に対する循環バイオマーカー |
| WO2011133504A2 (en) | 2010-04-20 | 2011-10-27 | University Of Florida Research Foundation, Inc. | Nanozymes, methods of making nanozymes, and methods of using nanozymes |
| US9901600B2 (en) * | 2011-03-11 | 2018-02-27 | Children's Medical Center Corporation | Methods and compositions relating to mesenchymal stem cell exosomes |
| CA2871089A1 (en) * | 2011-04-20 | 2012-10-26 | Smith Holdings, Llc | Methods and compositions for modulating gene expression using components that self assemble in cells and produce rnai activity |
| KR20140067001A (ko) * | 2011-08-08 | 2014-06-03 | 카리스 라이프 사이언스 룩셈부르크 홀딩스, 에스.에이.알.엘. | 생물지표 조성물 및 방법 |
| US9777042B2 (en) | 2011-12-15 | 2017-10-03 | Morehouse School Of Medicine | Method of purifying HIV/SIV Nef from exosomal fusion proteins |
| US9921223B2 (en) | 2013-12-04 | 2018-03-20 | Board Of Regents, The University Of Texas System | Analysis of genomic DNA, RNA, and proteins in exosomes for diagnosis and theranosis |
| HUE059718T2 (hu) * | 2016-09-02 | 2022-12-28 | Dicerna Pharmaceuticals Inc | 4'-foszfát analógok és azokat tartalmazó oligonukleotidok |
-
2014
- 2014-03-14 BR BR112015023275-2A patent/BR112015023275B1/pt not_active IP Right Cessation
- 2014-03-14 US US14/775,716 patent/US20160024503A1/en not_active Abandoned
- 2014-03-14 EP EP14770497.7A patent/EP2971162B1/en active Active
- 2014-03-14 CA CA2905081A patent/CA2905081C/en active Active
- 2014-03-14 PT PT191512201T patent/PT3527670T/pt unknown
- 2014-03-14 CN CN201480022292.7A patent/CN105264092B/zh active Active
- 2014-03-14 JP JP2016502475A patent/JP6554458B2/ja not_active Expired - Fee Related
- 2014-03-14 ES ES19151220T patent/ES2966571T3/es active Active
- 2014-03-14 WO PCT/US2014/027541 patent/WO2014152622A1/en not_active Ceased
- 2014-03-14 RU RU2018101152A patent/RU2018101152A/ru not_active Application Discontinuation
- 2014-03-14 RU RU2015144212A patent/RU2644247C2/ru active
- 2014-03-14 AU AU2014239309A patent/AU2014239309B2/en not_active Ceased
- 2014-03-14 CA CA3209023A patent/CA3209023A1/en active Pending
- 2014-03-14 KR KR1020157028765A patent/KR102183406B1/ko active Active
- 2014-03-14 EP EP19151220.1A patent/EP3527670B1/en active Active
- 2014-03-14 MX MX2015013141A patent/MX373957B/es active IP Right Grant
- 2014-03-14 CN CN201910120129.9A patent/CN109852695B/zh active Active
- 2014-03-14 HK HK16106127.5A patent/HK1218143A1/zh unknown
-
2015
- 2015-09-09 IL IL241409A patent/IL241409B/en active IP Right Grant
- 2015-09-15 MX MX2020005165A patent/MX2020005165A/es unknown
-
2018
- 2018-06-06 JP JP2018108450A patent/JP6807351B2/ja active Active
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2020
- 2020-03-23 US US16/827,343 patent/US11926824B2/en active Active
- 2020-04-06 IL IL273829A patent/IL273829B/en unknown
- 2020-06-01 AU AU2020203590A patent/AU2020203590B2/en active Active
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