JP2016520059A - ムベ葉抽出物を有効成分として含む骨組織生成促進用薬学組成物 - Google Patents
ムベ葉抽出物を有効成分として含む骨組織生成促進用薬学組成物 Download PDFInfo
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Abstract
Description
Claims (8)
- ムベ葉粗抽出物を有効成分として含む骨または軟骨組織生成促進用薬学組成物。
- 前記ムベ葉粗抽出物は、水、メタノール、エタノール、プロパノール、イソプロパノール、ブタノールまたはこれらの混合溶媒から選ばれるいずれか一つから選ばれる可溶抽出物であることを特徴とする、請求項1に記載のムベ葉粗抽出物を含有する骨または軟骨組織生成促進用薬学組成物。
- 前記溶媒を使用して抽出したムベ葉粗抽出物は、非極性溶媒としてへキサン、クロロホルム、ジクロロメタン及びエチルアセテートから選ばれるいずれか一つを分画溶媒として使用して分画したことを特徴とする、請求項2に記載のムベ葉粗抽出物を含有する骨または軟骨組織生成促進用薬学組成物。
- 請求項1〜3のいずれか1項に記載の組成物は0.01重量%〜99.9重量%で含まれることを特徴とするムベ葉粗抽出物を含有する骨または軟骨組織生成促進用薬学組成物。
- 前記抽出物の1日当たりの投与量は、体重kg当たりに10mg/kg〜1000mg/kgの量で供給されることを特徴とする、請求項4に記載のムベ葉粗抽出物を含む骨または軟骨組織生成促進用薬学組成物。
- 前記組成物は、散剤、顆粒剤、錠剤、カプセル剤、懸濁液、エマルジョン、シロップ、エアロゾル、経皮剤、坐剤または滅菌注射用液に剤形化されたことを特徴とする、請求項4または5に記載のムベ葉粗抽出物を含む骨または軟骨組織生成促進用薬学組成物。
- 前記抽出物は、歯周炎、骨粗鬆症の予防または治療用に使用されることを特徴とする、請求項1〜6のいずれか1項に記載のムベ葉粗抽出物を含む骨または軟骨組織生成促進用薬学組成物。
- 請求項1〜3のいずれか1項に記載の骨または軟骨組織生成促進用薬学組成物を0.01重量%〜99.9重量%で含む歯周炎または骨粗鬆症改善及び予防用機能性健康食品。
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
KR1020130076190A KR101532832B1 (ko) | 2013-06-30 | 2013-06-30 | 멀꿀 잎 추출물을 유효성분으로 포함하는 골조직 생성 촉진용 약학 조성물 |
KR10-2013-0076190 | 2013-06-30 | ||
PCT/KR2014/003742 WO2015002378A1 (ko) | 2013-06-30 | 2014-04-29 | 멀꿀 잎 추출물을 유효성분으로 포함하는 골조직 생성 촉진용 약학 조성물 |
Publications (2)
Publication Number | Publication Date |
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JP2016520059A true JP2016520059A (ja) | 2016-07-11 |
JP6104462B2 JP6104462B2 (ja) | 2017-03-29 |
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KR102038108B1 (ko) * | 2016-12-29 | 2019-10-29 | 영진약품 주식회사 | 멀꿀 잎 추출물로부터 분리된 신규한 카페인산 화합물 및 이를 유효성분으로 하는 항염, 골조직 생성 또는 연골조직 생성 촉진용 조성물 |
KR102038107B1 (ko) * | 2016-12-29 | 2019-10-29 | 영진약품 주식회사 | 멀꿀 잎 추출물로부터 분리된 신규한 플라보노이드 화합물 및 이를 유효성분으로 하는 항염, 골조직 생성 또는 연골조직 생성 촉진용 조성물 |
CN107259256B (zh) * | 2017-07-18 | 2020-12-29 | 福建农林大学 | 一种五指那藤功能饮品及其制备方法 |
KR102126575B1 (ko) * | 2017-11-03 | 2020-06-24 | 영진약품 주식회사 | 멀꿀 잎 유래 추출물 또는 분획 정제물 또는 이로부터 분리된 신규 플라보노이드 화합물 및 카페인산 화합물을 유효성분으로 포함하는 항염, 또는 골조직 생성 또는 연골조직 생성 촉진용 약학적 조성물 |
KR102241369B1 (ko) * | 2020-02-25 | 2021-04-15 | 영진약품 주식회사 | 멀꿀 잎 유래 추출물 또는 분획 정제물 또는 이로부터 분리된 신규 플라보노이드 화합물 및 카페인산 화합물을 유효성분으로 포함하는 항염, 또는 골조직 생성 또는 연골조직 생성 촉진용 약학적 조성물 |
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JP2011195532A (ja) * | 2010-03-23 | 2011-10-06 | Shiseido Co Ltd | タンパク質糖化抑制剤 |
JP2011201811A (ja) * | 2010-03-25 | 2011-10-13 | Shiseido Co Ltd | Tie2活性化剤、血管の成熟化、正常化又は安定化剤、リンパ管安定化剤並びにしわ防止・改善剤及びむくみ改善・予防剤 |
WO2012133825A1 (ja) * | 2011-03-31 | 2012-10-04 | 株式会社資生堂 | ホットフラッシュの抑制剤 |
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KR100497945B1 (ko) * | 2001-06-26 | 2005-06-29 | 한국 한의학 연구원 | 성장호르몬 분비촉진용 생약추출물 |
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KR101243115B1 (ko) * | 2012-04-17 | 2013-03-12 | 재단법인 전라남도생물산업진흥재단 | 멀꿀 잎 추출물을 포함하는 해열제 |
KR20130020095A (ko) * | 2011-08-18 | 2013-02-27 | 재단법인 전라남도생물산업진흥재단 | 멀꿀 추출물을 포함하는 간 보호용 조성물 |
KR101167589B1 (ko) | 2011-08-18 | 2012-07-27 | 재단법인 전라남도생물산업진흥재단 | 멀꿀 열매 추출물을 포함하는 항염증제 |
KR101317668B1 (ko) | 2012-09-03 | 2013-10-15 | 재단법인 전라남도생물산업진흥재단 | 멀꿀 잎 추출물을 유효성분으로 포함하는 관절염 치료 또는 예방용 약학 조성물 |
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JP2011195532A (ja) * | 2010-03-23 | 2011-10-06 | Shiseido Co Ltd | タンパク質糖化抑制剤 |
JP2011201811A (ja) * | 2010-03-25 | 2011-10-13 | Shiseido Co Ltd | Tie2活性化剤、血管の成熟化、正常化又は安定化剤、リンパ管安定化剤並びにしわ防止・改善剤及びむくみ改善・予防剤 |
WO2012133825A1 (ja) * | 2011-03-31 | 2012-10-04 | 株式会社資生堂 | ホットフラッシュの抑制剤 |
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KR101532832B1 (ko) | 2015-06-30 |
EP3031465A1 (en) | 2016-06-15 |
WO2015002378A1 (ko) | 2015-01-08 |
KR20150002398A (ko) | 2015-01-07 |
CN105407903B (zh) | 2020-08-07 |
CN111494474A (zh) | 2020-08-07 |
CA2911745A1 (en) | 2015-01-08 |
EP3031465B1 (en) | 2019-11-13 |
US10328110B2 (en) | 2019-06-25 |
CN105407903A (zh) | 2016-03-16 |
PL3031465T3 (pl) | 2020-05-18 |
AU2014284932A1 (en) | 2015-11-26 |
CA2911745C (en) | 2019-08-06 |
AU2014284932B2 (en) | 2017-09-14 |
EP3031465A4 (en) | 2017-03-01 |
ES2767351T3 (es) | 2020-06-17 |
JP6104462B2 (ja) | 2017-03-29 |
US20160113979A1 (en) | 2016-04-28 |
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