JP2016519955A5 - - Google Patents
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- Publication number
- JP2016519955A5 JP2016519955A5 JP2016516662A JP2016516662A JP2016519955A5 JP 2016519955 A5 JP2016519955 A5 JP 2016519955A5 JP 2016516662 A JP2016516662 A JP 2016516662A JP 2016516662 A JP2016516662 A JP 2016516662A JP 2016519955 A5 JP2016519955 A5 JP 2016519955A5
- Authority
- JP
- Japan
- Prior art keywords
- animal
- chromosome
- factor
- marker
- exogenous gene
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- 241001465754 Metazoa Species 0.000 claims 19
- 210000002593 Y chromosome Anatomy 0.000 claims 11
- 210000004027 cell Anatomy 0.000 claims 10
- 238000000034 method Methods 0.000 claims 8
- 108090000623 proteins and genes Proteins 0.000 claims 8
- 239000003550 marker Substances 0.000 claims 6
- 244000144972 livestock Species 0.000 claims 5
- 101710163270 Nuclease Proteins 0.000 claims 3
- 210000001161 mammalian embryo Anatomy 0.000 claims 3
- 230000035935 pregnancy Effects 0.000 claims 3
- 239000003053 toxin Substances 0.000 claims 3
- 231100000765 toxin Toxicity 0.000 claims 3
- 238000012800 visualization Methods 0.000 claims 3
- 241000251468 Actinopterygii Species 0.000 claims 2
- 241000283690 Bos taurus Species 0.000 claims 2
- 241000283707 Capra Species 0.000 claims 2
- 241000287828 Gallus gallus Species 0.000 claims 2
- 241000283973 Oryctolagus cuniculus Species 0.000 claims 2
- 241001494479 Pecora Species 0.000 claims 2
- 241001493546 Suina Species 0.000 claims 2
- 241000282898 Sus scrofa Species 0.000 claims 2
- 239000000427 antigen Substances 0.000 claims 2
- 102000036639 antigens Human genes 0.000 claims 2
- 108091007433 antigens Proteins 0.000 claims 2
- 210000002257 embryonic structure Anatomy 0.000 claims 2
- 230000001448 gametogenic effect Effects 0.000 claims 2
- 239000003446 ligand Substances 0.000 claims 2
- 230000004083 survival effect Effects 0.000 claims 2
- 230000004075 alteration Effects 0.000 claims 1
- 239000000729 antidote Substances 0.000 claims 1
- 230000001640 apoptogenic effect Effects 0.000 claims 1
- 239000003795 chemical substances by application Substances 0.000 claims 1
- 230000002759 chromosomal effect Effects 0.000 claims 1
- 210000000349 chromosome Anatomy 0.000 claims 1
- 238000010367 cloning Methods 0.000 claims 1
- 210000003495 flagella Anatomy 0.000 claims 1
- 230000004927 fusion Effects 0.000 claims 1
- 231100000518 lethal Toxicity 0.000 claims 1
- 230000001665 lethal effect Effects 0.000 claims 1
- 238000004519 manufacturing process Methods 0.000 claims 1
- 102000004169 proteins and genes Human genes 0.000 claims 1
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201361829672P | 2013-05-31 | 2013-05-31 | |
| US61/829,672 | 2013-05-31 | ||
| US201361870586P | 2013-08-27 | 2013-08-27 | |
| US61/870,586 | 2013-08-27 | ||
| PCT/US2014/035851 WO2014193584A2 (en) | 2013-05-31 | 2014-04-29 | Genetic techniques for making animals with sortable sperm |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2016519955A JP2016519955A (ja) | 2016-07-11 |
| JP2016519955A5 true JP2016519955A5 (enExample) | 2017-06-15 |
Family
ID=51986778
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2016516662A Pending JP2016519955A (ja) | 2013-05-31 | 2014-04-29 | 選別可能な精子を有する動物を作製するための遺伝子技術 |
Country Status (13)
| Country | Link |
|---|---|
| US (1) | US20140359795A1 (enExample) |
| EP (1) | EP3003021A4 (enExample) |
| JP (1) | JP2016519955A (enExample) |
| KR (1) | KR20160015333A (enExample) |
| CN (1) | CN105658050A (enExample) |
| AP (1) | AP2015008966A0 (enExample) |
| AU (1) | AU2014272107A1 (enExample) |
| BR (1) | BR112015029905A2 (enExample) |
| CA (1) | CA2913412A1 (enExample) |
| MX (1) | MX2015016383A (enExample) |
| PH (1) | PH12015502646A1 (enExample) |
| RU (1) | RU2015156824A (enExample) |
| WO (1) | WO2014193584A2 (enExample) |
Families Citing this family (16)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DK3456831T3 (da) | 2013-04-16 | 2021-09-06 | Regeneron Pharma | Målrettet modifikation af rottegenom |
| US20140359796A1 (en) * | 2013-05-31 | 2014-12-04 | Recombinetics, Inc. | Genetically sterile animals |
| ES2962492T3 (es) | 2013-10-25 | 2024-03-19 | Livestock Improvement Corporation Ltd | Marcadores genéticos y usos de los mismos |
| CN111218447B (zh) | 2013-11-07 | 2024-10-11 | 爱迪塔斯医药有限公司 | 使用统治型gRNA的CRISPR相关方法和组合物 |
| US10787684B2 (en) * | 2013-11-19 | 2020-09-29 | President And Fellows Of Harvard College | Large gene excision and insertion |
| MX388127B (es) | 2013-12-11 | 2025-03-19 | Regeneron Pharma | Metodos y composiciones para la modificacion dirigida de un genoma. |
| BR122023023211A2 (pt) | 2014-04-28 | 2024-01-23 | Recombinetics, Inc. | Método de fazer edições de genes multiplex em uma célula de vertebrado ou de embrião primário não-humano |
| DK3161128T3 (en) | 2014-06-26 | 2018-11-05 | Regeneron Pharma | METHODS AND COMPOSITIONS FOR TARGETED GENTICAL MODIFICATIONS AND PROCEDURES FOR USE THEREOF |
| EP3221457B1 (en) | 2014-11-21 | 2019-03-20 | Regeneron Pharmaceuticals, Inc. | Methods and compositions for targeted genetic modification using paired guide rnas |
| CN108368502B (zh) | 2015-06-03 | 2022-03-18 | 内布拉斯加大学董事委员会 | 使用单链dna的dna编辑 |
| CN107315092B (zh) * | 2017-07-11 | 2019-03-19 | 上海市第一人民医院 | 一种快速评估睾丸生精功能的免疫荧光染色法及其试剂盒 |
| WO2020102565A2 (en) * | 2018-11-14 | 2020-05-22 | Flagship Pioneering Innovations V, Inc. | Systems and methods for nondestructive testing of gametes |
| CN111500530A (zh) * | 2020-04-30 | 2020-08-07 | 延安大学 | 一种通用型动物精子分选方法及x精子质控方法 |
| CN114015705A (zh) * | 2021-11-28 | 2022-02-08 | 华中科技大学同济医学院附属协和医院 | 一种小鼠体外受精繁育性别选择方法 |
| WO2024249570A2 (en) * | 2023-06-02 | 2024-12-05 | New York University | Single-sex chicken with toxin-antitoxin system |
| CN119498221B (zh) * | 2024-11-12 | 2026-07-17 | 南京农业大学 | 一种公猪阴囊智能降温机器人及其工作方法 |
Family Cites Families (14)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2000029602A1 (en) * | 1998-11-13 | 2000-05-25 | Cedars-Sinai Medical Center | Transfection of male germ cells for generation of selectable transgenic stem cells |
| GB9916810D0 (en) * | 1999-07-16 | 1999-09-22 | Cancer Res Campaign Tech | Killing cells |
| US20010041348A1 (en) * | 1999-12-07 | 2001-11-15 | Stan Blecher | Sex-chromosome-specific proteins, species specific and sperm specific proteins and methods for their identification and isolation |
| CN1434678A (zh) * | 1999-12-27 | 2003-08-06 | 刘成宇 | 通过将转基因靶向至性染色体上控制子代性别比例 |
| CN101024829A (zh) * | 2000-02-24 | 2007-08-29 | 马萨诸塞大学 | 只生育单一性别后代的哺乳动物的生产 |
| US20050081256A1 (en) * | 2001-03-22 | 2005-04-14 | Forsberg Erik J. | Sex- specific selection of sperm from transgenic animals |
| CN1313061C (zh) * | 2002-03-11 | 2007-05-02 | 刘凤鸣 | 一种动物精子的性别分选方法 |
| JP4271120B2 (ja) * | 2003-10-14 | 2009-06-03 | 独立行政法人科学技術振興機構 | Ｙ染色体標識トランスジェニック非ヒト動物 |
| CN101014700B (zh) * | 2004-03-29 | 2012-03-28 | 英格朗公司 | 用于分选带有x或y染色体富集群的精子悬浮液 |
| US20060123489A1 (en) * | 2004-12-03 | 2006-06-08 | Envivo Pharmaceuticals, Inc. | Sex-specific automated sorting of non-human animals |
| CA2793945A1 (en) * | 2009-04-01 | 2011-10-21 | Biocern, Inc. | Sperm cell separation methods and compositions containing sperm cell targeting ligands for use therein |
| US8633348B2 (en) * | 2009-08-28 | 2014-01-21 | Novartis Forschungsstiftung, Zweigniederlassung, Friedrich Miescher Institute For Biomedical Research | Genetic vasectomy by overexpression of PRML-EGFP fusion protein in spermatids |
| MX363013B (es) * | 2011-02-25 | 2019-03-04 | Recombinetics Inc | Animales genéticamente modificados y métodos para su obtención. |
| CN102199606B (zh) * | 2011-03-09 | 2012-12-26 | 塔里木大学 | 一种筛选非人哺乳动物xy精子差异表达基因的方法 |
-
2014
- 2014-04-28 US US14/263,431 patent/US20140359795A1/en not_active Abandoned
- 2014-04-29 AP AP2015008966A patent/AP2015008966A0/xx unknown
- 2014-04-29 WO PCT/US2014/035851 patent/WO2014193584A2/en not_active Ceased
- 2014-04-29 MX MX2015016383A patent/MX2015016383A/es unknown
- 2014-04-29 CA CA2913412A patent/CA2913412A1/en not_active Abandoned
- 2014-04-29 BR BR112015029905A patent/BR112015029905A2/pt not_active Application Discontinuation
- 2014-04-29 EP EP14804017.3A patent/EP3003021A4/en not_active Withdrawn
- 2014-04-29 CN CN201480042059.5A patent/CN105658050A/zh active Pending
- 2014-04-29 RU RU2015156824A patent/RU2015156824A/ru not_active Application Discontinuation
- 2014-04-29 AU AU2014272107A patent/AU2014272107A1/en not_active Abandoned
- 2014-04-29 KR KR1020157037264A patent/KR20160015333A/ko not_active Withdrawn
- 2014-04-29 JP JP2016516662A patent/JP2016519955A/ja active Pending
-
2015
- 2015-11-26 PH PH12015502646A patent/PH12015502646A1/en unknown
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