KR20160015333A - 분류가능한 정자를 갖는 동물을 만들기 위한 유전적 기술 - Google Patents

분류가능한 정자를 갖는 동물을 만들기 위한 유전적 기술 Download PDF

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Publication number
KR20160015333A
KR20160015333A KR1020157037264A KR20157037264A KR20160015333A KR 20160015333 A KR20160015333 A KR 20160015333A KR 1020157037264 A KR1020157037264 A KR 1020157037264A KR 20157037264 A KR20157037264 A KR 20157037264A KR 20160015333 A KR20160015333 A KR 20160015333A
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South Korea
Prior art keywords
sperm
marker
animal
chromosome
cells
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KR1020157037264A
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English (en)
Korean (ko)
Inventor
다니엘 에프. 칼슨
스캇 씨. 파렌크루그
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리컴비네틱스 인코포레이티드
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Publication of KR20160015333A publication Critical patent/KR20160015333A/ko
Withdrawn legal-status Critical Current

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    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01K—ANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
    • A01K67/00—Rearing or breeding animals, not otherwise provided for; New or modified breeds of animals
    • A01K67/027—New or modified breeds of vertebrates
    • A01K67/0275—Genetically modified vertebrates, e.g. transgenic
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/87—Introduction of foreign genetic material using processes not otherwise provided for, e.g. co-transformation
    • C12N15/873—Techniques for producing new embryos, e.g. nuclear transfer, manipulation of totipotent cells or production of chimeric embryos
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01K—ANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
    • A01K2217/00—Genetically modified animals
    • A01K2217/05—Animals comprising random inserted nucleic acids (transgenic)
    • A01K2217/052—Animals comprising random inserted nucleic acids (transgenic) inducing gain of function
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01K—ANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
    • A01K2227/00—Animals characterised by species
    • A01K2227/10—Mammal
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01K—ANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
    • A01K2267/00—Animals characterised by purpose
    • A01K2267/02—Animal zootechnically ameliorated

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  • Life Sciences & Earth Sciences (AREA)
  • Environmental Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Biotechnology (AREA)
  • Zoology (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Animal Husbandry (AREA)
  • Biodiversity & Conservation Biology (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Genetics & Genomics (AREA)
  • Chemical & Material Sciences (AREA)
  • Biomedical Technology (AREA)
  • General Engineering & Computer Science (AREA)
  • Wood Science & Technology (AREA)
  • Reproductive Health (AREA)
  • Cell Biology (AREA)
  • Organic Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Developmental Biology & Embryology (AREA)
  • Biochemistry (AREA)
  • Microbiology (AREA)
  • Biophysics (AREA)
  • Plant Pathology (AREA)
  • Molecular Biology (AREA)
  • Physics & Mathematics (AREA)
  • Immunology (AREA)
  • Virology (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Public Health (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
KR1020157037264A 2013-05-31 2014-04-29 분류가능한 정자를 갖는 동물을 만들기 위한 유전적 기술 Withdrawn KR20160015333A (ko)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US201361829672P 2013-05-31 2013-05-31
US61/829,672 2013-05-31
US201361870586P 2013-08-27 2013-08-27
US61/870,586 2013-08-27
PCT/US2014/035851 WO2014193584A2 (en) 2013-05-31 2014-04-29 Genetic techniques for making animals with sortable sperm

Publications (1)

Publication Number Publication Date
KR20160015333A true KR20160015333A (ko) 2016-02-12

Family

ID=51986778

Family Applications (1)

Application Number Title Priority Date Filing Date
KR1020157037264A Withdrawn KR20160015333A (ko) 2013-05-31 2014-04-29 분류가능한 정자를 갖는 동물을 만들기 위한 유전적 기술

Country Status (13)

Country Link
US (1) US20140359795A1 (enExample)
EP (1) EP3003021A4 (enExample)
JP (1) JP2016519955A (enExample)
KR (1) KR20160015333A (enExample)
CN (1) CN105658050A (enExample)
AP (1) AP2015008966A0 (enExample)
AU (1) AU2014272107A1 (enExample)
BR (1) BR112015029905A2 (enExample)
CA (1) CA2913412A1 (enExample)
MX (1) MX2015016383A (enExample)
PH (1) PH12015502646A1 (enExample)
RU (1) RU2015156824A (enExample)
WO (1) WO2014193584A2 (enExample)

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* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SI2986729T1 (sl) 2013-04-16 2019-02-28 Regeneron Pharmaceuticals, Inc. Ciljana sprememba genoma podgane
US20140359796A1 (en) * 2013-05-31 2014-12-04 Recombinetics, Inc. Genetically sterile animals
MX388563B (es) 2013-10-25 2025-03-20 Livestock Improvement Corporation Ltd Marcadores geneticos y usos de los mismos.
EP4372090A3 (en) 2013-11-07 2024-08-07 Editas Medicine, Inc. Crispr-related methods and compositions with governing grnas
US10787684B2 (en) * 2013-11-19 2020-09-29 President And Fellows Of Harvard College Large gene excision and insertion
CN110951779B (zh) 2013-12-11 2024-04-16 瑞泽恩制药公司 用于靶向修饰基因组的方法和组合物
MX2016014066A (es) 2014-04-28 2017-05-03 Recombinetics Inc Edicion de genes multiples en cerdos.
RU2771532C2 (ru) 2014-06-26 2022-05-05 Регенерон Фармасьютикалз, Инк. Способы и композиции для нацеленных генетических модификаций и способы их применения
BR112017010547A2 (pt) 2014-11-21 2018-02-27 Regeneron Pharma métodos para produção de uma modificação bialélica, modificação de um genoma dentro de uma célula, produção de uma geração f0 de um animal não humano e identificação de uma inserção de um inserto de ácido nucleico.
EP3303585A4 (en) 2015-06-03 2018-10-31 Board of Regents of the University of Nebraska Dna editing using single-stranded dna
CN107315092B (zh) * 2017-07-11 2019-03-19 上海市第一人民医院 一种快速评估睾丸生精功能的免疫荧光染色法及其试剂盒
WO2020102565A2 (en) * 2018-11-14 2020-05-22 Flagship Pioneering Innovations V, Inc. Systems and methods for nondestructive testing of gametes
CN111500530A (zh) * 2020-04-30 2020-08-07 延安大学 一种通用型动物精子分选方法及x精子质控方法
CN114015705A (zh) * 2021-11-28 2022-02-08 华中科技大学同济医学院附属协和医院 一种小鼠体外受精繁育性别选择方法
WO2024249570A2 (en) * 2023-06-02 2024-12-05 New York University Single-sex chicken with toxin-antitoxin system

Family Cites Families (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2350829A1 (en) * 1998-11-13 2000-05-25 Cedars-Sinai Medical Center Transfection of male germ cells for generation of selectable transgenic stem cells
GB9916810D0 (en) * 1999-07-16 1999-09-22 Cancer Res Campaign Tech Killing cells
BR0016212A (pt) * 1999-12-07 2002-08-27 Univ Guelph Proteìna especìfica do cromossoma sexual e sequência de ácido nucleico isolada e purificada, método para identificar moléculas especìficas de cromossomas sexuais associadas com membranas celulares de esperma animal, anticorpo contra um epìtopo de uma molécula especìfica de cromossomas sexuais, métodos de triagem para uma molécula especifica de cromossomas sexuais, e para separar esperma determinante de macho e fêmea de sêmen nativo kit para executar um método, contraceptivo, proteìna especìfica do cromossoma sexual isolada e purificada, e , molécula
WO2001047353A1 (en) * 1999-12-27 2001-07-05 Chengyu Liu Controlling offspring's sex ratio by targeting transgenes onto the sex chromosomes
CN101024829A (zh) * 2000-02-24 2007-08-29 马萨诸塞大学 只生育单一性别后代的哺乳动物的生产
WO2002077637A1 (en) * 2001-03-22 2002-10-03 Infigen, Inc. Sex-specific selection of sperm from transgenic animals
CN1313061C (zh) * 2002-03-11 2007-05-02 刘凤鸣 一种动物精子的性别分选方法
JP4271120B2 (ja) * 2003-10-14 2009-06-03 独立行政法人科学技術振興機構 Ｙ染色体標識トランスジェニック非ヒト動物
CN101014700B (zh) * 2004-03-29 2012-03-28 英格朗公司 用于分选带有x或y染色体富集群的精子悬浮液
US20060123489A1 (en) * 2004-12-03 2006-06-08 Envivo Pharmaceuticals, Inc. Sex-specific automated sorting of non-human animals
CA2793945A1 (en) * 2009-04-01 2011-10-21 Biocern, Inc. Sperm cell separation methods and compositions containing sperm cell targeting ligands for use therein
EP2470557A1 (en) * 2009-08-28 2012-07-04 Novartis Forschungsstiftung, Zweigniederlassung Friedrich Miescher Institute For Biomedical Research Genetic vasectomy by overexpression of prml-egfp fusion protein in spermatids
EP3461898A1 (en) * 2011-02-25 2019-04-03 The University Court Of The University of Edinburgh Genetically modified animals and methods for making the same
CN102199606B (zh) * 2011-03-09 2012-12-26 塔里木大学 一种筛选非人哺乳动物xy精子差异表达基因的方法

Also Published As

Publication number Publication date
BR112015029905A2 (pt) 2017-09-26
EP3003021A4 (en) 2016-11-02
AP2015008966A0 (en) 2015-12-31
PH12015502646A1 (en) 2016-03-07
AU2014272107A1 (en) 2016-01-21
WO2014193584A3 (en) 2015-08-06
JP2016519955A (ja) 2016-07-11
RU2015156824A (ru) 2017-07-05
US20140359795A1 (en) 2014-12-04
WO2014193584A2 (en) 2014-12-04
EP3003021A2 (en) 2016-04-13
MX2015016383A (es) 2016-09-29
CN105658050A (zh) 2016-06-08
CA2913412A1 (en) 2014-12-04

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PA0105 International application

Patent event date: 20151231

Patent event code: PA01051R01D

Comment text: International Patent Application

PG1501 Laying open of application
PC1203 Withdrawal of no request for examination
WITN Application deemed withdrawn, e.g. because no request for examination was filed or no examination fee was paid