JP2016519052A5 - - Google Patents
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- JP2016519052A5 JP2016519052A5 JP2015562513A JP2015562513A JP2016519052A5 JP 2016519052 A5 JP2016519052 A5 JP 2016519052A5 JP 2015562513 A JP2015562513 A JP 2015562513A JP 2015562513 A JP2015562513 A JP 2015562513A JP 2016519052 A5 JP2016519052 A5 JP 2016519052A5
- Authority
- JP
- Japan
- Prior art keywords
- protein
- ppm
- acid
- sodium
- tris
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201361787309P | 2013-03-15 | 2013-03-15 | |
| US61/787,309 | 2013-03-15 | ||
| PCT/IB2014/059755 WO2014141150A1 (en) | 2013-03-15 | 2014-03-13 | Methods for purifying antibodies |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2019182562A Division JP7002511B2 (ja) | 2013-03-15 | 2019-10-03 | 抗体を精製するための方法 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2016519052A JP2016519052A (ja) | 2016-06-30 |
| JP2016519052A5 true JP2016519052A5 (enExample) | 2017-03-30 |
| JP6599773B2 JP6599773B2 (ja) | 2019-10-30 |
Family
ID=50391244
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2015562513A Active JP6599773B2 (ja) | 2013-03-15 | 2014-03-13 | 抗体を精製するための方法 |
| JP2019182562A Active JP7002511B2 (ja) | 2013-03-15 | 2019-10-03 | 抗体を精製するための方法 |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2019182562A Active JP7002511B2 (ja) | 2013-03-15 | 2019-10-03 | 抗体を精製するための方法 |
Country Status (15)
| Country | Link |
|---|---|
| US (3) | US10676503B2 (enExample) |
| EP (3) | EP4371996A3 (enExample) |
| JP (2) | JP6599773B2 (enExample) |
| KR (1) | KR102114021B1 (enExample) |
| CN (1) | CN105188872B (enExample) |
| AU (1) | AU2014229280B2 (enExample) |
| BR (1) | BR112015022321A2 (enExample) |
| CA (1) | CA2902287A1 (enExample) |
| DK (2) | DK3680000T3 (enExample) |
| ES (2) | ES2765206T3 (enExample) |
| IL (1) | IL240753B (enExample) |
| RU (1) | RU2651483C2 (enExample) |
| SG (1) | SG11201506494XA (enExample) |
| TW (1) | TWI625335B (enExample) |
| WO (1) | WO2014141150A1 (enExample) |
Families Citing this family (14)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| TWI625335B (zh) | 2013-03-15 | 2018-06-01 | Glaxosmithkline Intellectual Property (No. 2) Limited | 純化抗體的方法 |
| JP2016519145A (ja) | 2013-05-15 | 2016-06-30 | メディミューン リミテッド | 組換え産生ポリペプチドの精製 |
| ES2857582T3 (es) | 2014-04-30 | 2021-09-29 | Novo Nordisk As | Métodos para la purificación de proteínas mediante el uso de ácido caprílico |
| WO2016121701A1 (ja) | 2015-01-26 | 2016-08-04 | 株式会社カネカ | 免疫グロブリンκ鎖可変領域含有タンパク質精製用アフィニティー分離マトリックス |
| CN108064286A (zh) | 2015-01-26 | 2018-05-22 | 株式会社钟化 | 突变型免疫球蛋白κ链可变区结合性肽 |
| WO2017195638A1 (ja) | 2016-05-09 | 2017-11-16 | 株式会社カネカ | 抗体またはκ鎖可変領域含有抗体断片の精製方法 |
| RU2759909C2 (ru) | 2016-09-07 | 2021-11-18 | Глэксосмитклайн Интеллекчуал Проперти Дивелопмент Лимитед | Способы очистки антител |
| CN106939045B (zh) * | 2017-05-01 | 2020-03-31 | 深圳市国创纳米抗体技术有限公司 | 一种单克隆抗体细胞培养液澄清的方法 |
| CN108085358A (zh) * | 2018-02-08 | 2018-05-29 | 保定冀中药业有限公司 | 一种犬细小病毒单克隆抗体IgG2b-Fab片段的制备方法 |
| TW202000891A (zh) * | 2018-03-07 | 2020-01-01 | 英商葛蘭素史克智慧財產發展有限公司 | 純化抗體之方法 |
| TW202003555A (zh) * | 2018-03-07 | 2020-01-16 | 英商葛蘭素史克智慧財產發展有限公司 | 用於純化重組多肽之方法 |
| CN116234619A (zh) * | 2020-08-18 | 2023-06-06 | 赛多利斯比亚分离有限责任公司 | 宿主细胞dna的金属亲和提取 |
| CN114133446A (zh) * | 2021-12-31 | 2022-03-04 | 方坦思(上海)生物医药有限公司 | 单克隆抗体的纯化方法 |
| CN116179582A (zh) * | 2022-09-27 | 2023-05-30 | 南京医事达生物科技有限公司 | 一种通用型基因重组蛋白质a亲和纯化填料制备方法和应用 |
Family Cites Families (17)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS57106673A (en) | 1980-12-24 | 1982-07-02 | Chugai Pharmaceut Co Ltd | Dibenzo(b,f)(1,4)oxazepin derivative |
| GB8607679D0 (en) | 1986-03-27 | 1986-04-30 | Winter G P | Recombinant dna product |
| US5429746A (en) * | 1994-02-22 | 1995-07-04 | Smith Kline Beecham Corporation | Antibody purification |
| US6955917B2 (en) | 1997-06-20 | 2005-10-18 | Bayer Healthcare Llc | Chromatographic method for high yield purification and viral inactivation of antibodies |
| IL127127A0 (en) | 1998-11-18 | 1999-09-22 | Peptor Ltd | Small functional units of antibody heavy chain variable regions |
| EP1584242B1 (en) * | 2001-06-01 | 2010-01-20 | Upfront Chromatography A/S | Fractionation of protein containing mixtures |
| CA2457636C (en) | 2001-08-10 | 2012-01-03 | Aberdeen University | Antigen binding domains |
| CN100403028C (zh) | 2002-05-31 | 2008-07-16 | 印度农业研究委员会 | Bt-cry毒素的迅速检测 |
| ES2407380T5 (es) * | 2004-02-27 | 2017-07-07 | Octapharma Ag | Procedimiento para proporcionar una preparación de anticuerpos purificada, sin riesgo respecto a virus |
| EP1786827A4 (en) * | 2004-05-14 | 2008-10-29 | Kirin Holdings Kk | PROCESS FOR IMMUNOGLOBULINE CLEANING |
| US8263750B2 (en) * | 2006-03-16 | 2012-09-11 | Amgen Inc. | Method for purifying a protein using protein-A affinity chromatography using an intermediate wash step |
| AR062711A1 (es) | 2006-09-08 | 2008-11-26 | Wyeth Corp | Lavado de arginina en l a purificacion de proteinas usando cromatografia de afinidad |
| WO2008085988A1 (en) * | 2007-01-05 | 2008-07-17 | Amgen Inc. | Methods of purifying proteins |
| JP6147726B2 (ja) * | 2011-03-29 | 2017-06-14 | グラクソスミスクライン・リミテッド・ライアビリティ・カンパニーＧｌａｘｏＳｍｉｔｈＫｌｉｎｅ ＬＬＣ | タンパク質精製のためのバッファー系 |
| TWI625335B (zh) * | 2013-03-15 | 2018-06-01 | Glaxosmithkline Intellectual Property (No. 2) Limited | 純化抗體的方法 |
| JP2016519145A (ja) | 2013-05-15 | 2016-06-30 | メディミューン リミテッド | 組換え産生ポリペプチドの精製 |
| EP3683232A1 (en) | 2013-09-13 | 2020-07-22 | F. Hoffmann-La Roche AG | Methods and compositions comprising purified recombinant polypeptides |
-
2014
- 2014-03-13 TW TW103108898A patent/TWI625335B/zh active
- 2014-03-13 RU RU2015136860A patent/RU2651483C2/ru active
- 2014-03-13 CA CA2902287A patent/CA2902287A1/en not_active Abandoned
- 2014-03-13 BR BR112015022321A patent/BR112015022321A2/pt not_active Application Discontinuation
- 2014-03-13 WO PCT/IB2014/059755 patent/WO2014141150A1/en not_active Ceased
- 2014-03-13 EP EP24155364.3A patent/EP4371996A3/en active Pending
- 2014-03-13 SG SG11201506494XA patent/SG11201506494XA/en unknown
- 2014-03-13 ES ES14713926T patent/ES2765206T3/es active Active
- 2014-03-13 JP JP2015562513A patent/JP6599773B2/ja active Active
- 2014-03-13 US US14/775,868 patent/US10676503B2/en active Active
- 2014-03-13 ES ES19198005T patent/ES2978309T3/es active Active
- 2014-03-13 CN CN201480016016.XA patent/CN105188872B/zh active Active
- 2014-03-13 AU AU2014229280A patent/AU2014229280B2/en not_active Ceased
- 2014-03-13 KR KR1020157029042A patent/KR102114021B1/ko active Active
- 2014-03-13 DK DK19198005.1T patent/DK3680000T3/da active
- 2014-03-13 EP EP19198005.1A patent/EP3680000B1/en active Active
- 2014-03-13 DK DK14713926.5T patent/DK2969098T3/da active
- 2014-03-13 EP EP14713926.5A patent/EP2969098B1/en active Active
-
2015
- 2015-08-23 IL IL240753A patent/IL240753B/en active IP Right Grant
-
2019
- 2019-10-03 JP JP2019182562A patent/JP7002511B2/ja active Active
-
2020
- 2020-05-13 US US15/931,062 patent/US12358945B2/en active Active
-
2025
- 2025-06-12 US US19/235,815 patent/US20250353878A1/en active Pending
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