JP2016518388A - 乾燥粉末配合および使用方法 - Google Patents

乾燥粉末配合および使用方法 Download PDF

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Publication number
JP2016518388A
JP2016518388A JP2016511717A JP2016511717A JP2016518388A JP 2016518388 A JP2016518388 A JP 2016518388A JP 2016511717 A JP2016511717 A JP 2016511717A JP 2016511717 A JP2016511717 A JP 2016511717A JP 2016518388 A JP2016518388 A JP 2016518388A
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JP
Japan
Prior art keywords
inhalation
dry powder
particles
dry
less
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Pending
Application number
JP2016511717A
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English (en)
Japanese (ja)
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JP2016518388A5 (https=
Inventor
ヤディディ、カンビズ
Original Assignee
オティトピック インク．
オティトピック インク．
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Publication of JP2016518388A publication Critical patent/JP2016518388A/ja
Publication of JP2016518388A5 publication Critical patent/JP2016518388A5/ja
Pending legal-status Critical Current

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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/007—Pulmonary tract; Aromatherapy
    • A61K9/0073—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy
    • A61K9/0075—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy for inhalation via a dry powder inhaler [DPI], e.g. comprising micronized drug mixed with lactose carrier particles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/60—Salicylic acid; Derivatives thereof
    • A61K31/612—Salicylic acid; Derivatives thereof having the hydroxy group in position 2 esterified, e.g. salicylsulfuric acid
    • A61K31/616—Salicylic acid; Derivatives thereof having the hydroxy group in position 2 esterified, e.g. salicylsulfuric acid by carboxylic acids, e.g. acetylsalicylic acid
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M15/00—Inhalators
    • A61M15/0028—Inhalators using prepacked dosages, one for each application, e.g. capsules to be perforated or broken-up
    • A61M15/0045—Inhalators using prepacked dosages, one for each application, e.g. capsules to be perforated or broken-up using multiple prepacked dosages on a same carrier, e.g. blisters
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M2202/00—Special media to be introduced, removed or treated
    • A61M2202/06—Solids
    • A61M2202/064—Powder
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
    • Y10T428/00—Stock material or miscellaneous articles
    • Y10T428/29—Coated or structually defined flake, particle, cell, strand, strand portion, rod, filament, macroscopic fiber or mass thereof
    • Y10T428/2982—Particulate matter [e.g., sphere, flake, etc.]

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  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical & Material Sciences (AREA)
  • Pulmonology (AREA)
  • Epidemiology (AREA)
  • Hematology (AREA)
  • Anesthesiology (AREA)
  • Biomedical Technology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Otolaryngology (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Diabetes (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
JP2016511717A 2013-04-30 2013-07-24 乾燥粉末配合および使用方法 Pending JP2016518388A (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201361817435P 2013-04-30 2013-04-30
US61/817,435 2013-04-30
PCT/US2013/051895 WO2014178891A1 (en) 2013-04-30 2013-07-24 Dry powder formulations and methods of use

Related Child Applications (1)

Application Number Title Priority Date Filing Date
JP2019034152A Division JP2019089843A (ja) 2013-04-30 2019-02-27 乾燥粉末配合および使用方法

Publications (2)

Publication Number Publication Date
JP2016518388A true JP2016518388A (ja) 2016-06-23
JP2016518388A5 JP2016518388A5 (https=) 2016-09-01

Family

ID=48917722

Family Applications (4)

Application Number Title Priority Date Filing Date
JP2016511717A Pending JP2016518388A (ja) 2013-04-30 2013-07-24 乾燥粉末配合および使用方法
JP2019034152A Pending JP2019089843A (ja) 2013-04-30 2019-02-27 乾燥粉末配合および使用方法
JP2021035890A Active JP7623854B2 (ja) 2013-04-30 2021-03-06 乾燥粉末配合および使用方法
JP2023062960A Abandoned JP2023086774A (ja) 2013-04-30 2023-04-07 乾燥粉末配合および使用方法

Family Applications After (3)

Application Number Title Priority Date Filing Date
JP2019034152A Pending JP2019089843A (ja) 2013-04-30 2019-02-27 乾燥粉末配合および使用方法
JP2021035890A Active JP7623854B2 (ja) 2013-04-30 2021-03-06 乾燥粉末配合および使用方法
JP2023062960A Abandoned JP2023086774A (ja) 2013-04-30 2023-04-07 乾燥粉末配合および使用方法

Country Status (8)

Country Link
US (3) US10149823B2 (https=)
EP (2) EP2991634A1 (https=)
JP (4) JP2016518388A (https=)
CN (1) CN105473133A (https=)
AU (1) AU2013388034B2 (https=)
CA (1) CA2910766C (https=)
HK (2) HK1218720A1 (https=)
WO (1) WO2014178891A1 (https=)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US9757395B2 (en) 2012-12-20 2017-09-12 Otitopic Inc. Dry powder inhaler and methods of use
US9757529B2 (en) 2012-12-20 2017-09-12 Otitopic Inc. Dry powder inhaler and methods of use
HK1218720A1 (zh) * 2013-04-30 2017-03-10 欧缇托匹克公司 干粉制剂及使用方法
ES2922206T3 (es) 2014-02-20 2022-09-09 Otitopic Inc Formulaciones de polvo seco para la inhalación
ES2942297T3 (es) * 2014-07-31 2023-05-31 Vectura Inc Formulaciones de polvo seco para inhalación
WO2017100656A1 (en) * 2015-12-11 2017-06-15 Otitopic Inc. Dry powder formulations of aspirin for inhalation
EP3393517B1 (en) * 2015-12-22 2021-08-11 AspiAir GmbH Acetylsalicylic acid for use in the treatment of moderate to severe influenza
US10568894B2 (en) * 2016-06-03 2020-02-25 Otitopic Inc. Dry powder formulations for inhalation
US11096949B2 (en) 2017-05-30 2021-08-24 Rhoshan Pharmaceuticals, Inc. In-vial deposition of a stable, sterile and crystalline O-acetyl salicylic acid
US10786456B2 (en) 2017-09-22 2020-09-29 Otitopic Inc. Inhaled aspirin and magnesium to treat inflammation
KR102681843B1 (ko) 2017-09-22 2024-07-05 벡추라 인코포레이티드 스테아르산마그네슘을 갖는 건조 분말 조성물
US12397004B2 (en) 2018-11-05 2025-08-26 Rush University Medical Center Nasal delivery of low-dose aspirin for the treatment of neurodegenerative and lysosomal storage diseases
WO2022011210A1 (en) * 2020-07-10 2022-01-13 Sean Downing Treatment for severe acute respiratory illness associated with coronavirus

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