JP2016516754A5 - - Google Patents

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JP2016516754A5
JP2016516754A5 JP2016506618A JP2016506618A JP2016516754A5 JP 2016516754 A5 JP2016516754 A5 JP 2016516754A5 JP 2016506618 A JP2016506618 A JP 2016506618A JP 2016506618 A JP2016506618 A JP 2016506618A JP 2016516754 A5 JP2016516754 A5 JP 2016516754A5
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Japan
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antigens
nanoparticle composition
antigen
nanoparticle
composition according
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Ceased
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JP2016506618A
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Japanese (ja)
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JP2016516754A (ja
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Priority claimed from PCT/US2014/032838 external-priority patent/WO2014165679A1/en
Publication of JP2016516754A publication Critical patent/JP2016516754A/ja
Publication of JP2016516754A5 publication Critical patent/JP2016516754A5/ja
Ceased legal-status Critical Current

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JP2016506618A 2013-04-03 2014-04-03 新規のナノ粒子組成物 Ceased JP2016516754A (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201361808118P 2013-04-03 2013-04-03
US61/808,118 2013-04-03
PCT/US2014/032838 WO2014165679A1 (en) 2013-04-03 2014-04-03 Novel nanoparticle compositions

Related Child Applications (1)

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JP2018243080A Division JP6756810B2 (ja) 2013-04-03 2018-12-26 新規のナノ粒子組成物

Publications (2)

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JP2016516754A JP2016516754A (ja) 2016-06-09
JP2016516754A5 true JP2016516754A5 (enExample) 2017-06-01

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JP2016506618A Ceased JP2016516754A (ja) 2013-04-03 2014-04-03 新規のナノ粒子組成物
JP2018243080A Active JP6756810B2 (ja) 2013-04-03 2018-12-26 新規のナノ粒子組成物

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JP2018243080A Active JP6756810B2 (ja) 2013-04-03 2018-12-26 新規のナノ粒子組成物

Country Status (12)

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US (2) US9539217B2 (enExample)
EP (2) EP3760223A1 (enExample)
JP (2) JP2016516754A (enExample)
KR (1) KR102233251B1 (enExample)
CN (1) CN105188741A (enExample)
AU (1) AU2014248090B2 (enExample)
CA (1) CA2907915C (enExample)
IL (1) IL241807B (enExample)
MX (1) MX375502B (enExample)
SG (1) SG11201508113SA (enExample)
WO (1) WO2014165679A1 (enExample)
ZA (1) ZA201508106B (enExample)

Families Citing this family (33)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US9597385B2 (en) 2012-04-23 2017-03-21 Allertein Therapeutics, Llc Nanoparticles for treatment of allergy
US9492535B2 (en) 2013-03-14 2016-11-15 Aimmune Therapeutics, Inc. Peanut formulations and uses thereof
EP3760223A1 (en) 2013-04-03 2021-01-06 N-Fold Llc Nanoparticle composition for desensitizing a subject to peanut allergens
JP6554493B2 (ja) 2014-06-24 2019-07-31 ザ・トラスティーズ・オブ・プリンストン・ユニバーシティThe Trustees Of Princeton University 可溶性生物製剤、治療薬およびイメージング剤をカプセル化するためのプロセス
CA2916117C (en) * 2014-12-22 2023-02-28 Nishil Mohammed Pristine and surface functionalized cellulose nanocrystals (cncs) incorporated hydrogel beads and uses thereof
CN104689772B (zh) * 2015-03-06 2017-08-11 天津大学 多酚化学启发制备高分子微囊的方法
US11103461B2 (en) 2015-12-22 2021-08-31 The Trustees Of Princeton University Process for encapsulating soluble biologics, therapeutics, and imaging agents
CN106913520A (zh) * 2015-12-25 2017-07-04 上海医药集团股份有限公司 艾沙康唑的微粒给药组合物
JP6977206B2 (ja) * 2016-03-31 2021-12-08 富山県 自然免疫を活性化する粘膜ワクチン用アジュバント
EP3525760A4 (en) * 2016-10-14 2020-06-24 Icahn School of Medicine at Mount Sinai TREATMENT OF IMMUNOLOGICAL DISEASES WITH BERBERIN NANOPARTICLES
WO2019055539A1 (en) 2017-09-12 2019-03-21 Prudhomme Robert K CELLULOSIC POLYMER NANOPARTICLES AND METHODS OF FORMING THE SAME
CN109692327B (zh) * 2017-10-23 2022-04-08 华中科技大学 一种运载蜂毒肽的纳米颗粒的应用
JP2021501753A (ja) 2017-11-03 2021-01-21 ザ・トラスティーズ・オブ・プリンストン・ユニバーシティThe Trustees Of Princeton University 徐放性ナノキャリア製剤を形成するための疎水性イオン対化およびフラッシュナノ沈殿
KR102095355B1 (ko) 2018-01-12 2020-03-31 주식회사 엠디헬스케어 모르가넬라 속 세균 유래 나노소포 및 이의 용도
US12186436B2 (en) 2018-07-19 2025-01-07 The Trustees Of Princeton University Triblock copolymer stabilizers for the formation of nanoparticles encapsulating soluble biologics, therapeutics, and imaging agents
US11731099B2 (en) 2018-07-20 2023-08-22 The Trustees Of Princeton University Method for controlling encapsulation efficiency and burst release of water soluble molecules from nanoparticles and microparticles produced by inverse flash nanoprecipitation
EP3836801A4 (en) 2018-08-16 2022-05-18 Société des Produits Nestlé S.A. Peanut oral immunotherapy with maintenance dose
JP7169837B2 (ja) * 2018-10-03 2022-11-11 三菱鉛筆株式会社 筆記具用水性インク組成物
CN109776478B (zh) * 2018-12-04 2022-10-14 福州大学 源于草酸青霉的iso-Penicillixanthone A及在宫颈癌方面的应用
CN113891722A (zh) * 2018-12-20 2022-01-04 爱沐疗法公司 用于漏服剂量的花生口服免疫疗法给药计划表
WO2020136657A1 (en) * 2018-12-28 2020-07-02 Ramot At Tel-Aviv University Ltd. Polymeric nanovaccines and uses thereof
WO2020150623A1 (en) * 2019-01-18 2020-07-23 University Of Georgia Research Foundation, Inc. Salt nanoparticles and compositions and methods of use thereof
US10398744B1 (en) 2019-02-08 2019-09-03 King Saud University Synthesis of mustard seed nanoparticles
EP3965815A4 (en) 2019-05-10 2023-05-31 Société des Produits Nestlé S.A. METHOD OF IMPROVING THE QUALITY OF LIFE IN A PEANUT ALLERGY PATIENT
US20220387316A1 (en) * 2019-11-13 2022-12-08 The Regents Of The University Of Michigan Nanoemulsion compositions for treating aeroallergen associated allergy and inflammation
WO2021102186A1 (en) * 2019-11-20 2021-05-27 Aimmune Therapeutics, Inc. Methods and systems for managing distribution and treatment of a food allergy oral immunotherapy drug
EP4149513A4 (en) * 2020-05-11 2025-02-26 The University Of Southern California Oral delivery of nanoparticles for kidney disease
AU2022256497A1 (en) * 2021-04-16 2023-11-30 Cour Pharmaceuticals Development Company Inc. Treatment of peanut allergy with tolerizing nanoparticles
WO2023168022A1 (en) 2022-03-04 2023-09-07 Reset Pharmaceuticals, Inc. Co-crystals or salts comprising psilocybin
WO2024006870A2 (en) * 2022-06-29 2024-01-04 Massachusetts Institute Of Technology Structured nucleic acid templated architectures
CN120282796A (zh) * 2022-10-19 2025-07-08 库尔制药开发公司 用耐受性纳米颗粒治疗花生过敏
US12431000B2 (en) * 2024-02-27 2025-09-30 International Business Machines Corporation Detecting allergens using internet of things
WO2025212530A1 (en) 2024-04-01 2025-10-09 N-Fold Llc Nanoparticle manufacturing

Family Cites Families (191)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3977794A (en) 1974-07-15 1976-08-31 Coulter Electronics, Inc. Universal cell holder
DE2650306A1 (de) 1976-11-02 1978-05-03 Merck Patent Gmbh Antibakteriell wirkender wundverband und verfahren zu seiner herstellung
US4270537A (en) 1979-11-19 1981-06-02 Romaine Richard A Automatic hypodermic syringe
US4316885A (en) 1980-08-25 1982-02-23 Ayerst, Mckenna And Harrison, Inc. Acyl derivatives of rapamycin
EP0056782B1 (en) 1981-01-09 1984-08-01 Sandoz Ag Novel cyclosporins
US4894366A (en) 1984-12-03 1990-01-16 Fujisawa Pharmaceutical Company, Ltd. Tricyclo compounds, a process for their production and a pharmaceutical composition containing the same
US5254562A (en) 1984-12-03 1993-10-19 Fujisawa Pharmaceutical Company, Ltd. Tricyclo compounds, a process for their production and a pharmaceutical composition containing the same
US4596556A (en) 1985-03-25 1986-06-24 Bioject, Inc. Hypodermic injection apparatus
AU98530S (en) 1985-06-20 1987-11-05 Novartis Ag Subdivided membrane controlled transdermal device
US4650803A (en) 1985-12-06 1987-03-17 University Of Kansas Prodrugs of rapamycin
US4886499A (en) 1986-12-18 1989-12-12 Hoffmann-La Roche Inc. Portable injection appliance
GB8704027D0 (en) 1987-02-20 1987-03-25 Owen Mumford Ltd Syringe needle combination
US4798823A (en) 1987-06-03 1989-01-17 Merck & Co., Inc. New cyclosporin analogs with modified "C-9 amino acids"
US4940460A (en) 1987-06-19 1990-07-10 Bioject, Inc. Patient-fillable and non-invasive hypodermic injection device assembly
US4790824A (en) 1987-06-19 1988-12-13 Bioject, Inc. Non-invasive hypodermic injection device
US4941880A (en) 1987-06-19 1990-07-17 Bioject, Inc. Pre-filled ampule and non-invasive hypodermic injection device assembly
US5227467A (en) 1987-08-03 1993-07-13 Merck & Co., Inc. Immunosuppressive fluorinated cyclosporin analogs
US5339163A (en) 1988-03-16 1994-08-16 Canon Kabushiki Kaisha Automatic exposure control device using plural image plane detection areas
FR2638359A1 (fr) 1988-11-03 1990-05-04 Tino Dalto Guide de seringue avec reglage de la profondeur de penetration de l'aiguille dans la peau
US5008110A (en) 1988-11-10 1991-04-16 The Procter & Gamble Company Storage-stable transdermal patch
US5284826A (en) 1989-07-24 1994-02-08 Sandoz Ltd. 0-hydroxyethyl and acyloxyethyl derivatives of [ser]8 cyclosporins
US5064413A (en) 1989-11-09 1991-11-12 Bioject, Inc. Needleless hypodermic injection device
US5312335A (en) 1989-11-09 1994-05-17 Bioject Inc. Needleless hypodermic injection device
US5225194A (en) * 1989-11-13 1993-07-06 Ldc Research Corporation Aqueous diafiltration process for preparing acellular vaccines, against selected bacterial diseases
US5208228A (en) 1989-11-13 1993-05-04 Merck & Co., Inc. Aminomacrolides and derivatives having immunosuppressive activity
US5122511A (en) 1990-02-27 1992-06-16 Merck & Co., Inc. Immunosuppressive cyclosporin analogs with modified amino acids at position-8
US5190521A (en) 1990-08-22 1993-03-02 Tecnol Medical Products, Inc. Apparatus and method for raising a skin wheal and anesthetizing skin
PT98990A (pt) 1990-09-19 1992-08-31 American Home Prod Processo para a preparacao de esteres de acidos carboxilicos de rapamicina
US5143918A (en) 1990-10-11 1992-09-01 Merck & Co., Inc. Halomacrolides and derivatives having immunosuppressive activity
US5527288A (en) 1990-12-13 1996-06-18 Elan Medical Technologies Limited Intradermal drug delivery device and method for intradermal delivery of drugs
US5120842A (en) 1991-04-01 1992-06-09 American Home Products Corporation Silyl ethers of rapamycin
US5100883A (en) 1991-04-08 1992-03-31 American Home Products Corporation Fluorinated esters of rapamycin
US5118678A (en) 1991-04-17 1992-06-02 American Home Products Corporation Carbamates of rapamycin
US5250678A (en) 1991-05-13 1993-10-05 Merck & Co., Inc. O-aryl, O-alkyl, O-alkenyl and O-alkynylmacrolides having immunosuppressive activity
US5162334A (en) 1991-05-13 1992-11-10 Merck & Co., Inc. Amino O-alkyl, O-alkenyl and O-alkynlmacrolides having immunosuppressive activity
US5262533A (en) 1991-05-13 1993-11-16 Merck & Co., Inc. Amino O-aryl macrolides having immunosuppressive activity
US5565560A (en) 1991-05-13 1996-10-15 Merck & Co., Inc. O-Aryl,O-alkyl,O-alkenyl and O-alkynylmacrolides having immunosuppressive activity
US5120725A (en) 1991-05-29 1992-06-09 American Home Products Corporation Bicyclic rapamycins
US5120727A (en) 1991-05-29 1992-06-09 American Home Products Corporation Rapamycin dimers
US5169851A (en) 1991-08-07 1992-12-08 American Home Products Corporation Rapamycin analog as immunosuppressants and antifungals
US5202332A (en) 1991-08-07 1993-04-13 American Home Products Corporation Rapamycin analog as immunosuppressant
US5189042A (en) 1991-08-22 1993-02-23 Merck & Co. Inc. Fluoromacrolides having immunosuppressive activity
GB9118204D0 (en) 1991-08-23 1991-10-09 Weston Terence E Needle-less injector
US5208241A (en) 1991-09-09 1993-05-04 Merck & Co., Inc. N-heteroaryl, n-alkylheteroaryl, n-alkenylheteroaryl and n-alkynylheteroarylmacrolides having immunosuppressive activity
SE9102652D0 (sv) 1991-09-13 1991-09-13 Kabi Pharmacia Ab Injection needle arrangement
US5151413A (en) 1991-11-06 1992-09-29 American Home Products Corporation Rapamycin acetals as immunosuppressant and antifungal agents
US6911220B1 (en) 1992-02-19 2005-06-28 The General Hospital Corporation Allogeneic and xenogeneic transplantation
US5328483A (en) 1992-02-27 1994-07-12 Jacoby Richard M Intradermal injection device with medication and needle guard
US6010715A (en) 1992-04-01 2000-01-04 Bertek, Inc. Transdermal patch incorporating a polymer film incorporated with an active agent
US5284840A (en) 1992-06-12 1994-02-08 Merck & Co., Inc. Alkylidene macrolides having immunosuppressive activity
US5383851A (en) 1992-07-24 1995-01-24 Bioject Inc. Needleless hypodermic injection device
US5569189A (en) 1992-09-28 1996-10-29 Equidyne Systems, Inc. hypodermic jet injector
US5334144A (en) 1992-10-30 1994-08-02 Becton, Dickinson And Company Single use disposable needleless injector
US5258389A (en) 1992-11-09 1993-11-02 Merck & Co., Inc. O-aryl, O-alkyl, O-alkenyl and O-alkynylrapamycin derivatives
US5558869A (en) 1992-12-30 1996-09-24 University Of Arkansas Major peanut allergen ara h II
US5591767A (en) 1993-01-25 1997-01-07 Pharmetrix Corporation Liquid reservoir transdermal patch for the administration of ketorolac
US5504091A (en) 1993-04-23 1996-04-02 American Home Products Corporation Biotin esters of rapamycin
US5565215A (en) 1993-07-23 1996-10-15 Massachusettes Institute Of Technology Biodegradable injectable particles for imaging
US5543158A (en) 1993-07-23 1996-08-06 Massachusetts Institute Of Technology Biodegradable injectable nanoparticles
JPH09504308A (ja) 1993-07-23 1997-04-28 マサチューセッツ インスティチュート オブ テクノロジー 非直鎖状の親水性−疎水性マルチブロックコポリマーのナノ粒子およびマイクロ粒子
US5830877A (en) 1993-08-26 1998-11-03 The Regents Of The University Of California Method, compositions and devices for administration of naked polynucleotides which encode antigens and immunostimulatory
IT1261849B (it) 1993-09-02 1996-06-03 Avantgarde Spa Dispositivo medico per la somministrazione di principi attivi o farmaci a bassissimo dosaggio, in particolare di farmaci omeopatici.
WO1995024176A1 (en) 1994-03-07 1995-09-14 Bioject, Inc. Ampule filling device
US5466220A (en) 1994-03-08 1995-11-14 Bioject, Inc. Drug vial mixing and transfer device
US6207646B1 (en) 1994-07-15 2001-03-27 University Of Iowa Research Foundation Immunostimulatory nucleic acid molecules
EP0772619B2 (en) 1994-07-15 2010-12-08 The University of Iowa Research Foundation Immunomodulatory oligonucleotides
US6007845A (en) 1994-07-22 1999-12-28 Massachusetts Institute Of Technology Nanoparticles and microparticles of non-linear hydrophilic-hydrophobic multiblock copolymers
US5837533A (en) 1994-09-28 1998-11-17 American Home Products Corporation Complexes comprising a nucleic acid bound to a cationic polyamine having an endosome disruption agent
US5693648A (en) 1994-09-30 1997-12-02 Merck & Co., Inc. O-aryl, O-alkyl, O-alkenyl and O-alkynyl-macrolides having immunosuppressive activity
US5660854A (en) 1994-11-28 1997-08-26 Haynes; Duncan H Drug releasing surgical implant or dressing material
EP0805678B1 (en) 1995-01-05 2003-10-29 THE BOARD OF REGENTS acting for and on behalf of THE UNIVERSITY OF MICHIGAN Surface-modified nanoparticles and method of making and using same
US5599302A (en) 1995-01-09 1997-02-04 Medi-Ject Corporation Medical injection system and method, gas spring thereof and launching device using gas spring
US6126936A (en) 1995-03-10 2000-10-03 Biohybrid Technologies Llc Microcapsules and composite microreactors for immunoisolation of cells
KR100201352B1 (ko) 1995-03-16 1999-06-15 성재갑 단일주사 백신 제형
US5730723A (en) 1995-10-10 1998-03-24 Visionary Medical Products Corporation, Inc. Gas pressured needle-less injection device and method
DK0752245T3 (da) 1995-07-05 2002-09-09 Europ Economic Community Biokompatible og bionedbrydelige nanopartikler udviklet til absorption og afgivelse af proteinholdige lægemidler
DE19537012A1 (de) 1995-10-04 1997-04-10 Dietl Hans Cyclosporin(e) enhaltende pharmazeutische Zubereitung zur oralen Applikation und Verfahren zu ihrer Herstellung
US6835824B1 (en) 1995-12-29 2004-12-28 University Of Arkansas Peanut allergens and methods
JPH11507840A (ja) 1995-12-29 1999-07-13 ユニバーシティ オブ アーカンソー ピーナッツアレルゲンおよび方法
US20030202980A1 (en) 1995-12-29 2003-10-30 Caplan Michael J. Methods and reagents for decreasing clinical reaction to allergy
US5893397A (en) 1996-01-12 1999-04-13 Bioject Inc. Medication vial/syringe liquid-transfer apparatus
GB9607549D0 (en) 1996-04-11 1996-06-12 Weston Medical Ltd Spring-powered dispensing device
AU734665B2 (en) 1996-05-09 2001-06-21 General Hospital Corporation, The Mixed chimerism and tolerance
US5739432A (en) 1996-05-30 1998-04-14 The Regents Of The University Of California Ultrasonic characterization of single drops of liquids
US5709797A (en) 1996-06-05 1998-01-20 Poli Industria Chimica S.P.A. Method of isolating cyclosporins
US5774209A (en) 1996-10-08 1998-06-30 Spectronic Instruments, Inc. Transmittance cell for spectrophotometer
ATE292980T1 (de) 1996-10-11 2005-04-15 Univ California Immunostimulierende oligonucleotidekonjugate
EP1005368B1 (en) 1997-03-10 2009-09-02 Ottawa Hospital Research Institute Use of nucleic acids containing unmethylated CpG dinucleotide in combination with alum as adjuvants
PL336596A1 (en) * 1997-04-30 2000-07-03 Guilford Pharm Inc Biodegradable compositions with polycycloaliphatic phosphoesters, products containing them and methods of using them
US5993412A (en) 1997-05-19 1999-11-30 Bioject, Inc. Injection apparatus
US5948433A (en) 1997-08-21 1999-09-07 Bertek, Inc. Transdermal patch
US6342507B1 (en) 1997-09-05 2002-01-29 Isotechnika, Inc. Deuterated rapamycin compounds, method and uses thereof
US7399480B2 (en) 1997-09-26 2008-07-15 Abbott Laboratories Methods of administering tetrazole-containing rapamycin analogs with other therapeutic substances using medical devices
DE69840586D1 (de) 1997-10-08 2009-04-02 Isotechnika Inc Deuterierte Cyclosporin-analoga und ihre Verwendung als immunmodulierende Agenzien
IT1298087B1 (it) 1998-01-08 1999-12-20 Fiderm S R L Dispositivo per il controllo della profondita' di penetrazione di un ago, in particolare applicabile ad una siringa per iniezioni
DE69921773D1 (de) 1998-01-16 2004-12-16 Univ Johns Hopkins Orale verabreichung von nukleinsäure-impstoffen durch partikelkomplexe
JP4292262B2 (ja) 1998-01-30 2009-07-08 アラタイン セラピューティクス, エルエルシー 予後アレルギー試験または予後炎症試験
DE69940805D1 (de) 1998-01-31 2009-06-10 Sinai School Medicine Verfahren und reagenzien zur verminderung der klinischen reaktion zur allergie
US7879977B2 (en) 1998-01-31 2011-02-01 University Of Arkansas Methods and reagents for decreasing clinical reaction to allergy
US5965154A (en) 1998-03-17 1999-10-12 Plc Holding, L.L.C. Adhesive matrix type transdermal patch and method of manufacturing same
SE9801288D0 (sv) 1998-04-14 1998-04-14 Astra Ab Vaccine delivery system and metod of production
US6299875B1 (en) 1998-06-04 2001-10-09 Panacea Pharmaceuticals, Llc Methods to block IGE binding to cell surface receptors of mast cells
IL140899A0 (en) 1998-07-17 2002-02-10 Skyepharma Inc Lipid/polymer containing pharmaceutical compositions and processes for the preparation thereof
FR2785812B1 (fr) 1998-11-16 2002-11-29 Commissariat Energie Atomique Protheses bioactives, notamment a proprietes immunosuppressives, antistenose et antithrombose, et leur fabrication
US6551990B2 (en) 1998-12-07 2003-04-22 University Of Washington Methods of inhibiting ectopic calcification
JP2004538237A (ja) 1998-12-18 2004-12-24 シーア ファーマスーティカルズ エルエルシー 表面アレルゲンに対するアレルギー反応を減少させるための方法および組成物
CA2357413A1 (en) 1998-12-22 2000-06-29 Panacea Pharmaceuticals, Llc Sensitizing agents for the treatment of skin lesions
US20020009452A1 (en) 1999-02-10 2002-01-24 Michael Caplan Method for altering undesirable immune responses to polypeptides
AU3760100A (en) 1999-03-16 2000-10-04 Panacea Pharmaceuticals, Llc Immunostimulatory nucleic acids and antigens
US20020090381A1 (en) 1999-04-09 2002-07-11 H. Kim Bottomly System for controlling immune system response to antigen
WO2001014855A1 (en) 1999-08-20 2001-03-01 Charles William Robertson Liquid photometer using surface tension to contain sample
AU4139801A (en) 1999-12-06 2001-06-12 Board Of Trustees Of The University Of Arkansas, The Controlled delivery of antigens
US8246945B2 (en) 2000-04-06 2012-08-21 University Of Arkansas Methods and reagents for decreasing clinical reaction to allergy
ES2260078T3 (es) 2000-04-06 2006-11-01 Seer Pharmaceuticals, Llc. Sistema de administracion microbiana.
AU6815901A (en) 2000-06-02 2001-12-17 Zycos Inc Delivery systems for bioactive agents
WO2002030456A1 (en) 2000-10-12 2002-04-18 The University Of Tennessee Research Corporation Targeting drug/gene carriers to irradiated tissue
US6676963B1 (en) 2000-10-27 2004-01-13 Barnes-Jewish Hospital Ligand-targeted emulsions carrying bioactive agents
US6544543B1 (en) 2000-12-27 2003-04-08 Advanced Cardiovascular Systems, Inc. Periodic constriction of vessels to treat ischemic tissue
US6809826B2 (en) 2001-02-20 2004-10-26 Charles William Robertson Liquid photometer using surface tension to contain sample
AU2002233619A1 (en) 2001-02-26 2002-09-12 Zur Pierre Beserman Systems devices and methods for intrabody targeted delivery and reloading of therapeutic agents
EP1379227A4 (en) 2001-03-21 2007-12-12 Univ Kentucky Res Found MICROEMULSIONS AS PRECURSORS OF SOLID NANOPARTICLES
US20030153044A1 (en) 2001-05-14 2003-08-14 Monika Liljedahl Tissues or organs for use in xenotransplantation
US20030003591A1 (en) 2001-07-02 2003-01-02 Ortho-Clinical Diagnostics, Inc. Reaction vessel
US7081489B2 (en) 2001-08-09 2006-07-25 Florida State University Research Foundation Polymeric encapsulation of nanoparticles
US20040023897A1 (en) 2001-11-13 2004-02-05 Caplan Michael J. Methods for preventing or treating disease mediated by toxin-secreting bacteria
AU2002358947A1 (en) 2001-12-05 2003-06-17 Yissum Research Development Company Of The Hebrew University Of Jerusalem Nanoparticles containing polymeric nucleic acid homologs, pharmaceutical compositions and articles of manufacture containing same and methods of use thereof
US20030235619A1 (en) 2001-12-21 2003-12-25 Christine Allen Polymer-lipid delivery vehicles
US20040038303A1 (en) 2002-04-08 2004-02-26 Unger Gretchen M. Biologic modulations with nanoparticles
US7285289B2 (en) 2002-04-12 2007-10-23 Nagy Jon O Nanoparticle vaccines
CA2516116A1 (en) 2003-01-16 2004-08-05 St. John's University Nanoparticle based stabilization of ir fluorescent dyes
ATE371437T1 (de) 2003-02-17 2007-09-15 Peter Burkhard Peptidische nanoteilchen als arzneimittelabgabe- und antigen-display-systeme
AU2004269405A1 (en) 2003-09-02 2005-03-10 University Of North Carolina At Chapel Hill Biodegradable polymer-ligand conjugates and their uses in isolation of cellular subpopulations and in cryopreservation, culture and transplantation of cells
ES2246695B1 (es) 2004-04-29 2007-05-01 Instituto Cientifico Y Tecnologico De Navarra, S.A. Composicion estimuladora de la respuesta inmunitaria que comprende nanoparticulas a base de un copolimero de metil vinil eter y anhidrido maleico.
WO2006052285A2 (en) 2004-05-13 2006-05-18 The Trustees Of Columbia University In The City Of New York Polymeric nanoparticles and nanogels for extraction and release of compounds
EP1768692B8 (en) 2004-07-01 2015-06-17 Yale University Targeted and high density drug loaded polymeric materials
JP5117191B2 (ja) 2004-10-01 2013-01-09 ミダテック リミテッド 抗原及びアジュバントを含むナノ粒子、並びに免疫原性構造
US7375815B2 (en) 2004-10-12 2008-05-20 Agilent Technologies, Inc. Optical devices, systems and method for producing a collimated light path
US20060087650A1 (en) 2004-10-21 2006-04-27 Shen Thomas Y Cuvette holder for spectrophotometers
US20060109468A1 (en) 2004-11-24 2006-05-25 Evans Richard W Devices, methods, and systems for measuring an optical property of a sample
CA2597612C (en) 2005-02-11 2010-11-02 Nanodrop Technologies, Inc. Apparatus and method for measuring the signal from a fluorescing nanodrop contained by surface tension
DE602006000381T2 (de) 2005-04-28 2008-12-18 Nipro Corp., Osaka Bioabsorbierbare pharmazeutische Zusammensetzung enthaltend einen PLGA-Copolymer
US8252846B2 (en) 2005-05-10 2012-08-28 Emory University Strategies for delivery of active agents using micelles and particles
CA2605551A1 (en) 2005-05-10 2006-11-16 Naomi Balaban Compositions for administering rnaiii-inhibiting peptides
US20070026126A1 (en) 2005-08-01 2007-02-01 Bryan Hitchcock Sterol fortified beverages
EP1973608A1 (en) 2005-12-14 2008-10-01 Cytos Biotechnology AG Immunostimulatory nucleic acid packaged particles for the treatment of hypersensitivity
US8021689B2 (en) 2006-02-21 2011-09-20 Ecole Polytechnique Federale de Lausanne (“EPFL”) Nanoparticles for immunotherapy
US9188594B2 (en) 2006-12-06 2015-11-17 Yale University Nanoelectronic-enzyme linked immunosorbent assay system and method
US8889117B2 (en) 2007-02-15 2014-11-18 Yale University Modular nanoparticles for adaptable vaccines
US10265407B2 (en) 2007-02-15 2019-04-23 Yale University Modular nanodevices for smart adaptable vaccines
JP5443175B2 (ja) * 2007-02-22 2014-03-19 バクスター・インターナショナル・インコーポレイテッド 疎水性タンパク質を精製する方法
WO2008109347A2 (en) 2007-03-02 2008-09-12 Yale University Methods for ex vivo administration of drugs to grafts using polymeric nanoparticles
WO2009038591A1 (en) 2007-09-17 2009-03-26 Yale University Bile salt colloids and methods of making and using thereof
ES2376175T3 (es) * 2007-09-28 2012-03-09 Bind Biosciences, Inc. Direccionamiento a células de c�?ncer usando nanopart�?culas.
BRPI0817664A2 (pt) * 2007-10-12 2015-03-24 Massachusetts Inst Technology Nanopartículas, método para preparar nanopartículas e método para tratar terapeuticamente ou profilaticamente um indivíduo
GB0721081D0 (en) 2007-10-26 2007-12-05 Metcalfe Susan M Immuno-modulatory composition
US8629098B2 (en) 2008-01-15 2014-01-14 Yale University Compositions and methods for adoptive and active immunotherapy
US9737593B2 (en) 2008-03-19 2017-08-22 Yale University Carbon nanotube compositions and methods of use thereof
AU2009266940A1 (en) 2008-07-01 2010-01-07 Emory University Synergistic induction of humoral and cellular immunity by combinatorial activation of toll-like receptors
US20100031262A1 (en) 2008-07-31 2010-02-04 Baird-Gent Jill M Program Schedule Sub-Project Network and Calendar Merge
US8323696B2 (en) 2008-08-29 2012-12-04 Ecole Polytechnique Federale De Lausanne Nanoparticles for immunotherapy
US8343498B2 (en) * 2008-10-12 2013-01-01 Massachusetts Institute Of Technology Adjuvant incorporation in immunonanotherapeutics
WO2010059253A2 (en) 2008-11-24 2010-05-27 Massachusets Institute Of Technology Methods and compositions for localized agent delivery
CA2750098A1 (en) 2009-01-20 2010-07-29 Myelin Repair Foundation, Inc. Compositions and methods for induction of antigen-specific tolerance
US8822065B2 (en) 2009-03-11 2014-09-02 Samsung Sdi Co., Ltd. Rechargeable battery with current collector plate
US20120219545A1 (en) 2009-07-31 2012-08-30 Mount Sinai School Of Medicine Materials and methods for diagnosing and treating shellfish allergy
EP3492922B1 (en) 2009-09-14 2025-11-05 Icahn School of Medicine at Mount Sinai Methods for characterizing antibody binding affinity and epitope diversity in food allergy
US8727965B2 (en) 2010-03-05 2014-05-20 Tissue Genesis, Inc. Methods and compositions to support tissue integration and inosculation of transplanted tissue and transplanted engineered penile tissue with adipose stromal cells
WO2011150235A1 (en) 2010-05-27 2011-12-01 Allertein Therapeutics, Llc Methods and reagents for treating autoimmune disorders and/or graft rejection
JP2013531043A (ja) 2010-07-16 2013-08-01 ザ・ジョンズ・ホプキンス・ユニバーシティー 癌の免疫療法のための方法及び組成物
JP5909745B2 (ja) 2010-11-12 2016-04-27 クール ファーマシューティカルズ ディベロップメント カンパニー 炎症性疾患の治療薬、ならびにウイルスまたは細菌感染疾患の治療薬
CN103501812A (zh) 2011-04-29 2014-01-08 西莱克塔生物科技公司 用于过敏症治疗的致耐受性合成纳米载体
US9446175B2 (en) 2011-06-03 2016-09-20 Yale University Compositions and methods for treating and preventing neointimal stenosis
WO2013003157A1 (en) 2011-06-28 2013-01-03 Yale University Cell-free tissued engineered vascular grafts
EP3939572B1 (en) 2012-04-12 2024-03-27 Yale University Vehicles for controlled delivery of different pharmaceutical agents
US9597385B2 (en) 2012-04-23 2017-03-21 Allertein Therapeutics, Llc Nanoparticles for treatment of allergy
US20150150996A1 (en) 2012-06-06 2015-06-04 Northwestern University Compositions and methods for antigen-specific tolerance
KR20250052503A (ko) 2012-06-21 2025-04-18 노쓰웨스턴유니버시티 펩티드 접합된 입자
CA2921491C (en) 2012-08-23 2022-06-21 Susan Marie Metcalfe Neurotherapeutic nanoparticle compositions and devices
HK1220368A1 (zh) 2013-03-13 2017-05-05 Cour Pharmaceuticals Development Company 用於治疗炎症的免疫修饰性颗粒
EP3760223A1 (en) 2013-04-03 2021-01-06 N-Fold Llc Nanoparticle composition for desensitizing a subject to peanut allergens
JP6553033B2 (ja) 2013-08-13 2019-07-31 ノースウェスタン ユニバーシティ ペプチドコンジュゲート粒子
US20160228521A1 (en) 2013-09-16 2016-08-11 Allertein Therapeutics, Llc Managing immune responses in transplantation
CN105848649B (zh) 2013-11-01 2019-08-02 耶鲁大学 用于免疫疗法的模块化粒子
US10898593B2 (en) 2014-05-13 2021-01-26 Yale University Compositions for nanoconfinement induced contrast enhancement and methods of making and using thereof
WO2016057909A1 (en) 2014-10-10 2016-04-14 Cour Pharmaceuticals Development Company Immune-modifying particles for the treatment of ebola virus
MX2017015127A (es) 2015-05-27 2018-06-22 Univ Northwestern Particulas modificadas por carbohidratos y formulaciones en particulas para modular una respuesta inmunitaria.
WO2017075053A1 (en) 2015-10-26 2017-05-04 Cour Pharmaceuticals Development Company Inc. Immune-modifying particles for the treatment of malaria
AU2016379413B2 (en) 2015-12-23 2024-04-04 Cour Pharmaceuticals Development Company Inc. Covalent polymer-antigen conjugated particles
US20190365656A1 (en) 2016-01-04 2019-12-05 Cour Pharmaceuticals Development Company, Inc. Particles encapsulating fusion proteins containing linked epitopes
JP2019504895A (ja) 2016-02-09 2019-02-21 クール ファーマシューティカルズ ディベロップメント カンパニー インコーポレイテッド スギ花粉エピトープを封入するtimp(組織性メタロプロテアーゼ阻害因子)
US11484506B2 (en) 2016-02-18 2022-11-01 Cour Pharmaceuticals Development Company, Inc. Process for the preparation of tolerizing immune-modulating particles

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