JP2016515113A5 - - Google Patents

Info

Publication number

JP2016515113A5

JP2016515113A5 JP2015562511A JP2015562511A JP2016515113A5 JP 2016515113 A5 JP2016515113 A5 JP 2016515113A5 JP 2015562511 A JP2015562511 A JP 2015562511A JP 2015562511 A JP2015562511 A JP 2015562511A JP 2016515113 A5 JP2016515113 A5 JP 2016515113A5

Authority

JP

Japan

Prior art keywords

solution

item

seq

kit

peptide

Prior art date

2014-03-13

Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)

Granted

Links

• Espacenet
• Global Dossier
• Discuss

• 108090000765 processed proteins & peptides Proteins 0.000 claims description 39
• 150000001413 amino acids Chemical class 0.000 claims description 28
• 230000002265 prevention Effects 0.000 claims description 14
• 102000004196 processed proteins & peptides Human genes 0.000 claims description 14
• FWMNVWWHGCHHJJ-SKKKGAJSSA-N 4-amino-1-[(2r)-6-amino-2-[[(2r)-2-[[(2r)-2-[[(2r)-2-amino-3-phenylpropanoyl]amino]-3-phenylpropanoyl]amino]-4-methylpentanoyl]amino]hexanoyl]piperidine-4-carboxylic acid Chemical compound C([C@H](C(=O)N[C@H](CC(C)C)C(=O)N[C@H](CCCCN)C(=O)N1CCC(N)(CC1)C(O)=O)NC(=O)[C@H](N)CC=1C=CC=CC=1)C1=CC=CC=C1 FWMNVWWHGCHHJJ-SKKKGAJSSA-N 0.000 claims description 10
• 101800002011 Amphipathic peptide Proteins 0.000 claims description 6
• 238000012323 Endoscopic submucosal dissection Methods 0.000 claims description 6
• 238000012326 endoscopic mucosal resection Methods 0.000 claims description 6
• 230000002209 hydrophobic effect Effects 0.000 claims description 6
• 239000000017 hydrogel Substances 0.000 claims description 5
• 239000013543 active substance Substances 0.000 claims description 4
• 239000002121 nanofiber Substances 0.000 claims description 4
• 230000004962 physiological condition Effects 0.000 claims description 4
• 241000124008 Mammalia Species 0.000 claims description 3
• 239000003814 drug Substances 0.000 claims description 3
• 229940079593 drug Drugs 0.000 claims description 3
• 239000011148 porous material Substances 0.000 claims description 3
• CZMRCDWAGMRECN-UGDNZRGBSA-N Sucrose Chemical compound O[C@H]1[C@H](O)[C@@H](CO)O[C@@]1(CO)O[C@@H]1[C@H](O)[C@@H](O)[C@H](O)[C@@H](CO)O1 CZMRCDWAGMRECN-UGDNZRGBSA-N 0.000 claims description 2
• 229930006000 Sucrose Natural products 0.000 claims description 2
• 239000005720 sucrose Substances 0.000 claims description 2
• 239000000243 solution Substances 0.000 claims 41
• 210000000214 mouth Anatomy 0.000 claims 9
• 210000003800 pharynx Anatomy 0.000 claims 9
• 210000003238 esophagus Anatomy 0.000 claims 8
• 208000031481 Pathologic Constriction Diseases 0.000 claims 7
• 208000037804 stenosis Diseases 0.000 claims 7
• 230000036262 stenosis Effects 0.000 claims 7
• 150000001768 cations Chemical class 0.000 claims 6
• 239000007864 aqueous solution Substances 0.000 claims 2
• 230000001419 dependent effect Effects 0.000 claims 1
• 239000007788 liquid Substances 0.000 claims 1
• 238000000034 method Methods 0.000 description 61
• 210000001035 gastrointestinal tract Anatomy 0.000 description 25
• 206010061974 Gastrointestinal obstruction Diseases 0.000 description 14
• 238000001356 surgical procedure Methods 0.000 description 4
• 238000012544 monitoring process Methods 0.000 description 3
• 238000007865 diluting Methods 0.000 description 1
• 230000035876 healing Effects 0.000 description 1
• 238000003384 imaging method Methods 0.000 description 1
• 230000003902 lesion Effects 0.000 description 1
• 230000001737 promoting effect Effects 0.000 description 1