JP2016513623A5 - - Google Patents
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- Publication number
- JP2016513623A5 JP2016513623A5 JP2015560826A JP2015560826A JP2016513623A5 JP 2016513623 A5 JP2016513623 A5 JP 2016513623A5 JP 2015560826 A JP2015560826 A JP 2015560826A JP 2015560826 A JP2015560826 A JP 2015560826A JP 2016513623 A5 JP2016513623 A5 JP 2016513623A5
- Authority
- JP
- Japan
- Prior art keywords
- octylphenyl
- ethyl
- formula
- group
- propanediol
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| IN951/CHE/2013 | 2013-03-05 | ||
| IN951CH2013 | 2013-03-05 | ||
| PCT/IB2014/059423 WO2014136047A2 (en) | 2013-03-05 | 2014-03-04 | A process for the preparation of 2-amino-1,3-propane diol compounds and salts thereof |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2018194845A Division JP2019023224A (ja) | 2013-03-05 | 2018-10-16 | ２−アミノ−１，３−プロパンジオール化合物およびその塩の製造のための方法 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2016513623A JP2016513623A (ja) | 2016-05-16 |
| JP2016513623A5 true JP2016513623A5 (https=) | 2018-05-24 |
| JP6484567B2 JP6484567B2 (ja) | 2019-03-13 |
Family
ID=54198663
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2015560826A Active JP6484567B2 (ja) | 2013-03-05 | 2014-03-04 | ２−アミノ−１，３−プロパンジオール化合物およびその塩の製造のための方法 |
| JP2018194845A Pending JP2019023224A (ja) | 2013-03-05 | 2018-10-16 | ２−アミノ−１，３−プロパンジオール化合物およびその塩の製造のための方法 |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2018194845A Pending JP2019023224A (ja) | 2013-03-05 | 2018-10-16 | ２−アミノ−１，３−プロパンジオール化合物およびその塩の製造のための方法 |
Country Status (9)
| Country | Link |
|---|---|
| US (1) | US9815772B2 (https=) |
| EP (1) | EP2964210B1 (https=) |
| JP (2) | JP6484567B2 (https=) |
| KR (1) | KR102255357B1 (https=) |
| AU (1) | AU2014224237B2 (https=) |
| CA (1) | CA2903708C (https=) |
| ES (1) | ES2964891T3 (https=) |
| RU (1) | RU2663833C2 (https=) |
| WO (1) | WO2014136047A2 (https=) |
Families Citing this family (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| RU2627691C1 (ru) * | 2016-07-06 | 2017-08-10 | Олег Ростиславович Михайлов | Кристаллическая η-модификация 2-амино-2-(2-(4-октилфенил)этил)пропан-1,3-диол гидрохлорида, способ её получения и фармацевтическая композиция на её основе |
| WO2020165672A1 (en) | 2019-02-15 | 2020-08-20 | Shivalik Rasayan Limited | Process for preparation of highly pure fingolimod hydrochloride |
| WO2021167770A1 (en) * | 2020-02-18 | 2021-08-26 | Octagon Therapeutics, Inc. | Immune cell modulators |
Family Cites Families (13)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE69321823T2 (de) * | 1992-10-21 | 1999-06-02 | Taito Co., Ltd., Tokio/Tokyo | 2-amino-1, 3- propandiolverbindung und immunosuppressium |
| GB9624038D0 (en) * | 1996-11-19 | 1997-01-08 | Sandoz Ltd | Organic compounds |
| DK1129066T3 (da) * | 1998-11-11 | 2005-03-29 | Novartis Ag | Fremstilling af 2-amino-2-[2-(C2-20alkylphenyl)ethyl]propan-1,3-dioler |
| US20090170813A1 (en) * | 2005-10-18 | 2009-07-02 | Francine Acher | Hypophosphorous Acid Derivatives and their Therapeutical Applications |
| US20090176744A1 (en) * | 2007-11-02 | 2009-07-09 | Concert Pharmaceuticals, Inc. | Deuterated fingolimod |
| PT2356090T (pt) * | 2008-11-11 | 2017-10-16 | Novartis Ag | Formas cristalinas de fingolimod, hcl |
| JP2012508215A (ja) | 2008-11-11 | 2012-04-05 | ノバルティス アーゲー | 有機化合物 |
| JP2012518671A (ja) * | 2009-02-24 | 2012-08-16 | ノバルティス アーゲー | セラミド類似体代謝物 |
| WO2011009634A2 (en) * | 2009-07-24 | 2011-01-27 | Ratiopharm Gmbh | Process for producing fingolimod salts |
| WO2012041359A1 (en) * | 2010-10-01 | 2012-04-05 | Synthon B.V. | Process for making fingolimod |
| WO2012070059A1 (en) * | 2010-11-25 | 2012-05-31 | Shilpa Medicare Limited | Fingolimod polymorphs and their processes |
| US9216943B2 (en) * | 2011-04-29 | 2015-12-22 | Dr. Reddy's Laboratories Ltd. | Preparation of fingolimod and its salts |
| CN102796022B (zh) * | 2012-08-27 | 2015-03-25 | 南京华威医药科技开发有限公司 | 制备2-氨基-2-[2-(4-烷基苯基)乙基]-1,3-丙二醇盐酸盐的方法 |
-
2014
- 2014-03-04 US US14/772,739 patent/US9815772B2/en active Active
- 2014-03-04 AU AU2014224237A patent/AU2014224237B2/en active Active
- 2014-03-04 CA CA2903708A patent/CA2903708C/en active Active
- 2014-03-04 JP JP2015560826A patent/JP6484567B2/ja active Active
- 2014-03-04 RU RU2015139293A patent/RU2663833C2/ru active
- 2014-03-04 WO PCT/IB2014/059423 patent/WO2014136047A2/en not_active Ceased
- 2014-03-04 EP EP14760844.2A patent/EP2964210B1/en active Active
- 2014-03-04 ES ES14760844T patent/ES2964891T3/es active Active
- 2014-03-04 KR KR1020157026450A patent/KR102255357B1/ko active Active
-
2018
- 2018-10-16 JP JP2018194845A patent/JP2019023224A/ja active Pending
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