JP2016512198A5 - - Google Patents
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- JP2016512198A5 JP2016512198A5 JP2015561594A JP2015561594A JP2016512198A5 JP 2016512198 A5 JP2016512198 A5 JP 2016512198A5 JP 2015561594 A JP2015561594 A JP 2015561594A JP 2015561594 A JP2015561594 A JP 2015561594A JP 2016512198 A5 JP2016512198 A5 JP 2016512198A5
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- JP
- Japan
- Prior art keywords
- independently selected
- group
- optionally substituted
- hydrogen
- aliphatic
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
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Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201361773779P | 2013-03-06 | 2013-03-06 | |
| US61/773,779 | 2013-03-06 | ||
| PCT/US2014/020700 WO2014138212A1 (en) | 2013-03-06 | 2014-03-05 | CaMKII INHIBITORS AND USES THEREOF |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2016512198A JP2016512198A (ja) | 2016-04-25 |
| JP2016512198A5 true JP2016512198A5 (https=) | 2017-04-06 |
| JP6318180B2 JP6318180B2 (ja) | 2018-04-25 |
Family
ID=51491905
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2015561594A Expired - Fee Related JP6318180B2 (ja) | 2013-03-06 | 2014-03-05 | ＣａＭＫＩＩ阻害剤及びその使用 |
Country Status (7)
| Country | Link |
|---|---|
| US (1) | US9951061B2 (https=) |
| EP (1) | EP2964225B1 (https=) |
| JP (1) | JP6318180B2 (https=) |
| CN (1) | CN105517549B (https=) |
| AU (1) | AU2014225889B2 (https=) |
| CA (1) | CA2901155C (https=) |
| WO (1) | WO2014138212A1 (https=) |
Families Citing this family (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2016037106A1 (en) | 2014-09-05 | 2016-03-10 | Allosteros Therapeutics, Inc | CaMKII INHIBITORS AND USES THEREOF |
| JP6532737B2 (ja) * | 2015-04-01 | 2019-06-19 | 東ソー・ファインケム株式会社 | ヘテロアセン化合物の製造方法 |
| AR110252A1 (es) | 2016-11-30 | 2019-03-13 | Gilead Sciences Inc | Compuestos heterocíclicos fusionados como inhibidores de la quinasa cam |
| KR20240103036A (ko) * | 2017-07-06 | 2024-07-03 | 칠드런'즈 메디컬 센터 코포레이션 | 카테콜아민성 다형성 심실성 빈맥을 치료하거나 예방하기 위한 조성물 및 방법 |
| KR20200140805A (ko) | 2018-02-21 | 2020-12-16 | 브리스톨-마이어스 스큅 컴퍼니 | Camk2d 안티센스 올리고뉴클레오티드 및 그의 용도 |
| CN108904532B (zh) * | 2018-08-20 | 2021-07-27 | 上海市第一人民医院 | 一种富勒烯C60纳米晶体联合CaMKII抑制剂的组合物的应用 |
| EP4248953A4 (en) * | 2020-11-20 | 2024-05-22 | Sailing Pharmaceutical Technology Group Co., Ltd. | BRUCIGEL PLASTER AND PRODUCTION METHOD AND USE THEREOF |
| WO2024197267A1 (en) * | 2023-03-22 | 2024-09-26 | The Regents Of The University Of Colorado, A Body Corporate | Inhibitors of ca 2+/calmodulin-dependent protein kinase ii (camkii) that do not inhibit long-term potentiation (ltp) induction and therapeutic uses thereof |
| WO2025101615A1 (en) * | 2023-11-07 | 2025-05-15 | Cardurion Pharmaceuticals, Inc. | Polymorphs of a pyridinylimidazo[1,2-b]pyridazine |
Family Cites Families (13)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2001509808A (ja) | 1997-01-31 | 2001-07-24 | ザ ボード オブ トラスティーズ オブ ザ リーランド スタンフォード ジュニア ユニバーシティ | 多機能性カルシウム／カルモジュリン−依存性プロテインキナーゼの阻害による不整脈の処置 |
| US7320959B2 (en) | 2001-10-01 | 2008-01-22 | Vanderbilt University | Use of calmodulin kinase II inhibitors to treat myocardial dysfunction in structural heart disease |
| AU2003300522A1 (en) * | 2002-12-27 | 2004-07-22 | Bayer Healthcare Ag | 4-phenyl-pyrimido (4,5-b) indole derivatives |
| US20060057639A1 (en) * | 2004-06-16 | 2006-03-16 | Pitt Geoffrey S | CaMKII/calcium channel phosphorylation-related compositions and methods |
| EP1815867A4 (en) | 2004-11-02 | 2010-06-09 | Dainippon Sumitomo Pharma Co | COMBINATION PREPARATION FOR THE TREATMENT OF AUTOIMMUNE DISEASE |
| DE602006014540D1 (en) * | 2005-05-16 | 2010-07-08 | Irm Llc | Pyrrolopyridinderivate als proteinkinaseinhibitoren |
| WO2006127587A1 (en) * | 2005-05-20 | 2006-11-30 | Vertex Pharmaceuticals Incorporated | Pyrrolopyridines useful as inhibitors of protein kinase |
| EP1896472A1 (de) | 2005-06-09 | 2008-03-12 | Boehringer Ingelheim International GmbH | Alpha-carboline als cdk-1 inhibitoren |
| US20070208053A1 (en) * | 2006-01-19 | 2007-09-06 | Arnold Lee D | Fused heterobicyclic kinase inhibitors |
| TW200908968A (en) * | 2007-05-29 | 2009-03-01 | Sgx Pharmaceuticals Inc | Substituted pyrrolopyridines and pyrazolopyridines as kinase modulators |
| EP2161271A1 (en) * | 2008-09-08 | 2010-03-10 | Università Degli Studi Di Milano - Bicocca | Alpha-carboline inhibitors of NMP-ALK, RET, and Bcr-Abl |
| US8440656B2 (en) | 2009-06-22 | 2013-05-14 | University Of Iowa Research Foundation | Methods of treating pulmonary diseases and disorders by modulating calcium/calmodulin dependent protein kinase II activity |
| US8685969B2 (en) * | 2010-06-16 | 2014-04-01 | Bristol-Myers Squibb Company | Carboline carboxamide compounds useful as kinase inhibitors |
-
2014
- 2014-03-05 AU AU2014225889A patent/AU2014225889B2/en not_active Ceased
- 2014-03-05 EP EP14760472.2A patent/EP2964225B1/en active Active
- 2014-03-05 US US14/773,308 patent/US9951061B2/en active Active
- 2014-03-05 CA CA2901155A patent/CA2901155C/en active Active
- 2014-03-05 JP JP2015561594A patent/JP6318180B2/ja not_active Expired - Fee Related
- 2014-03-05 WO PCT/US2014/020700 patent/WO2014138212A1/en not_active Ceased
- 2014-03-05 CN CN201480012869.6A patent/CN105517549B/zh not_active Expired - Fee Related
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