|
AU600575B2
(en)
|
1987-03-18 |
1990-08-16 |
Sb2, Inc. |
Altered antibodies
|
|
US5892019A
(en)
|
1987-07-15 |
1999-04-06 |
The United States Of America, As Represented By The Department Of Health And Human Services |
Production of a single-gene-encoded immunoglobulin
|
|
US5468468A
(en)
|
1989-02-09 |
1995-11-21 |
The United States Of America, As Represented By The Secretary Of The Department Of Health & Human Services |
Method for making a monoclonal antibody, monoclonal antibodies to α PD
|
|
DE4205148A1
(de)
|
1991-05-25 |
1993-01-21 |
Boehringer Mannheim Gmbh |
Monoklonale antikoerper gegen c-kit
|
|
EP0590058B1
(en)
|
1991-06-14 |
2003-11-26 |
Genentech, Inc. |
HUMANIZED Heregulin ANTIBODy
|
|
US6696548B2
(en)
|
1993-12-03 |
2004-02-24 |
St. Jude Children's Research Hospital |
Antibodies for recognition of alk protein tyrosine/kinase receptor
|
|
US5731168A
(en)
|
1995-03-01 |
1998-03-24 |
Genentech, Inc. |
Method for making heteromultimeric polypeptides
|
|
US5686292A
(en)
|
1995-06-02 |
1997-11-11 |
Genentech, Inc. |
Hepatocyte growth factor receptor antagonist antibodies and uses thereof
|
|
DE19638745C2
(de)
|
1996-09-11 |
2001-05-10 |
Schering Ag |
Monoklonale Antikörper gegen die extrazelluläre Domäne des menschlichen VEGF - Rezeptorproteins (KDR)
|
|
US20020062010A1
(en)
|
1997-05-02 |
2002-05-23 |
Genentech, Inc. |
Method for making multispecific antibodies having heteromultimeric and common components
|
|
US6235883B1
(en)
|
1997-05-05 |
2001-05-22 |
Abgenix, Inc. |
Human monoclonal antibodies to epidermal growth factor receptor
|
|
US20020136721A1
(en)
*
|
1998-02-17 |
2002-09-26 |
Schwall Ralph H. |
Hepatocyte growth factor receptor antagonists and uses thereof
|
|
JP4334141B2
(ja)
|
1998-04-20 |
2009-09-30 |
グリカート バイオテクノロジー アクチェンゲゼルシャフト |
抗体依存性細胞傷害性を改善するための抗体のグリコシル化操作
|
|
CA2369292C
(en)
|
1999-04-09 |
2010-09-21 |
Kyowa Hakko Kogyo Co. Ltd. |
Method of modulating the activity of functional immune molecules
|
|
DE69934259T2
(de)
|
1999-07-23 |
2007-05-31 |
Glaxo Group Ltd., Greenford |
Kombination von einem Anti-Ep-CAM-Antikörper mit einem chemotherapeutischen Mittel
|
|
US8071072B2
(en)
|
1999-10-08 |
2011-12-06 |
Hoffmann-La Roche Inc. |
Cytotoxicity mediation of cells evidencing surface expression of CD44
|
|
WO2001029246A1
(fr)
|
1999-10-19 |
2001-04-26 |
Kyowa Hakko Kogyo Co., Ltd. |
Procede de production d'un polypeptide
|
|
JP4132547B2
(ja)
|
2000-03-01 |
2008-08-13 |
富士フイルム株式会社 |
画像形成材料及びそれを用いた平版印刷版原版
|
|
US20020119148A1
(en)
|
2000-09-01 |
2002-08-29 |
Gerritsen Mary E. |
ErbB4 antagonists
|
|
US7101976B1
(en)
|
2000-09-12 |
2006-09-05 |
Purdue Research Foundation |
EphA2 monoclonal antibodies and methods of making and using same
|
|
EA013563B1
(ru)
|
2000-10-06 |
2010-06-30 |
Киова Хакко Кирин Ко., Лтд. |
Трансгенное животное, продуцирующее антитела с измененными углеводными цепями, способ получения антител и содержащее антитела лекарственное средство
|
|
AU2001294175A1
(en)
|
2000-10-06 |
2002-04-22 |
Kyowa Hakko Kogyo Co. Ltd. |
Method of purifying antibody
|
|
AR032028A1
(es)
|
2001-01-05 |
2003-10-22 |
Pfizer |
Anticuerpos contra el receptor del factor de crecimiento similar a insulina
|
|
JP2005500018A
(ja)
|
2001-04-02 |
2005-01-06 |
アイデック ファーマスーティカルズ コーポレイション |
ＧｎＴＩＩＩと同時発現する組換え抗体
|
|
DK1383785T3
(da)
|
2001-05-03 |
2011-05-23 |
Merck Patent Gmbh |
Rekombinant tumorspecifikt antistof og anvendelse deraf
|
|
US6972324B2
(en)
|
2001-05-18 |
2005-12-06 |
Boehringer Ingelheim Pharmaceuticals, Inc. |
Antibodies specific for CD44v6
|
|
IL159177A0
(en)
|
2001-06-20 |
2004-06-01 |
Prochon Biotech Ltd |
Antibodies that block receptor protein tyrosine kinase activation, methods of screening for and uses thereof
|
|
JP4355571B2
(ja)
|
2001-07-19 |
2009-11-04 |
ウニベルジテート チューリッヒ |
ヒト可変ドメインの改変
|
|
ATE430580T1
(de)
|
2001-10-25 |
2009-05-15 |
Genentech Inc |
Glycoprotein-zusammensetzungen
|
|
ES2363765T3
(es)
|
2002-01-31 |
2011-08-16 |
MAX-PLANCK-Gesellschaft zur Förderung der Wissenschaften e.V. |
Agonistas de fgfr.
|
|
CA2478169C
(en)
|
2002-03-04 |
2013-04-16 |
Imclone Systems Incorporated |
Human antibodies specific to kdr and uses thereof
|
|
EP1575509B1
(en)
|
2002-05-10 |
2011-10-26 |
Purdue Research Foundation |
Epha2 agonistic monoclonal antibodies and methods of use thereof
|
|
US20080008713A1
(en)
|
2002-06-28 |
2008-01-10 |
Domantis Limited |
Single domain antibodies against tnfr1 and methods of use therefor
|
|
US7232888B2
(en)
|
2002-07-01 |
2007-06-19 |
Massachusetts Institute Of Technology |
Antibodies against tumor surface antigens
|
|
BRPI0407446A
(pt)
|
2003-02-13 |
2006-01-31 |
Pharmacia Corp |
Anticorpos para c-met para o tratamento de cânceres
|
|
ITMI20031127A1
(it)
|
2003-06-05 |
2004-12-06 |
Uni Degli Studi Del Piemont E Orientale Am |
Anticorpi anti-hgf-r e loro uso
|
|
HN2004000285A
(es)
|
2003-08-04 |
2006-04-27 |
Pfizer Prod Inc |
ANTICUERPOS DIRIGIDOS A c-MET
|
|
NZ545776A
(en)
|
2003-08-22 |
2009-05-31 |
Biogen Idec Inc |
Improved antibodies having altered effector function and methods for making the same
|
|
CA2762955A1
(en)
|
2003-10-16 |
2005-04-28 |
Imclone Llc |
Fibroblast growth factor receptor-1 inhibitors and methods of treatment thereof
|
|
WO2005063815A2
(en)
|
2003-11-12 |
2005-07-14 |
Biogen Idec Ma Inc. |
Fcϝ receptor-binding polypeptide variants and methods related thereto
|
|
CA2545603A1
(en)
|
2003-11-12 |
2005-05-26 |
Biogen Idec Ma Inc. |
Neonatal fc receptor (fcrn)-binding polypeptide variants, dimeric fc binding proteins and methods related thereto
|
|
WO2005063816A2
(en)
|
2003-12-19 |
2005-07-14 |
Genentech, Inc. |
Monovalent antibody fragments useful as therapeutics
|
|
AU2005287404B2
(en)
|
2004-07-22 |
2009-05-07 |
Genentech, Inc. |
HER2 antibody composition
|
|
US7476724B2
(en)
|
2004-08-05 |
2009-01-13 |
Genentech, Inc. |
Humanized anti-cmet antibodies
|
|
MY146381A
(en)
|
2004-12-22 |
2012-08-15 |
Amgen Inc |
Compositions and methods relating relating to anti-igf-1 receptor antibodies
|
|
KR101363252B1
(ko)
|
2005-02-04 |
2014-02-13 |
레이븐 바이오테크놀로지스, 인코퍼레이티드 |
Ｅｐｈａ2에 결합하는 항체 및 그것의 사용방법
|
|
EP2402374A1
(en)
|
2005-02-07 |
2012-01-04 |
GlycArt Biotechnology AG |
Antigen binding molecules that bind EGFR, vectors encoding same, and uses thereof
|
|
EP1868648B1
(en)
|
2005-03-25 |
2015-04-15 |
Genentech, Inc. |
Methods and compositions for modulating hyperstabilized c-met
|
|
MX2007013924A
(es)
|
2005-05-09 |
2008-01-28 |
Glycart Biotechnology Ag |
Moleculas que unen antigeno que tienen regiones fc modificadas y union alterada a receptores fc.
|
|
PT2100614E
(pt)
|
2005-06-17 |
2013-12-16 |
Imclone Llc |
Antagonistas de receptor para tratamento de cancro ósseo metastático
|
|
AR056857A1
(es)
|
2005-12-30 |
2007-10-24 |
U3 Pharma Ag |
Anticuerpos dirigidos hacia her-3 (receptor del factor de crecimiento epidérmico humano-3) y sus usos
|
|
AU2007213920B2
(en)
|
2006-02-09 |
2013-08-29 |
Amgen Research (Munich) Gmbh |
Treatment of metastatic breast cancer
|
|
US7951918B2
(en)
|
2006-03-17 |
2011-05-31 |
Biogen Idec Ma Inc. |
Stabilized polypeptide compositions
|
|
TW200815470A
(en)
|
2006-03-30 |
2008-04-01 |
Novartis Ag |
Compositions and methods of use for antibodies of c-Met
|
|
TWI395754B
(zh)
|
2006-04-24 |
2013-05-11 |
Amgen Inc |
人類化之ｃ-ｋｉｔ抗體
|
|
RU2460540C2
(ru)
|
2006-04-28 |
2012-09-10 |
Деленекс Терапьютикс Аг |
Антитела, связывающиеся с внеклеточным доменом тирозинкиназного рецептора (alk)
|
|
WO2008052796A1
(en)
|
2006-11-03 |
2008-05-08 |
U3 Pharma Gmbh |
Fgfr4 antibodies
|
|
UY30776A1
(es)
|
2006-12-21 |
2008-07-03 |
Medarex Inc |
Anticuerpos cd44
|
|
HRP20131113T1
(hr)
|
2007-02-16 |
2014-01-17 |
Merrimack Pharmaceuticals, Inc. |
Protutijela protiv erbb3 i njihova uporaba
|
|
EP1972637B1
(en)
|
2007-03-19 |
2011-06-29 |
Universität Stuttgart |
huTNFR1 selective antagonists
|
|
BRPI0810374A2
(pt)
|
2007-04-17 |
2014-10-29 |
Imclone Llc |
Inibidores específicos do pdgfrbeta
|
|
US20080260738A1
(en)
*
|
2007-04-18 |
2008-10-23 |
Moore Margaret D |
Single chain fc, methods of making and methods of treatment
|
|
WO2008131575A2
(en)
|
2007-04-27 |
2008-11-06 |
Esbatech Ag |
Anti-alk antibodies suitable for treating metastatic cancers or tumors
|
|
BRPI0811857A2
(pt)
|
2007-05-14 |
2014-10-21 |
Biogen Idec Inc |
Regiões fc (scfc) de cadeia simples, polipeptídeos de aglutinação que as compreendem e métodos relacionados.
|
|
EP2014681A1
(en)
|
2007-07-12 |
2009-01-14 |
Pierre Fabre Medicament |
Novel antibodies inhibiting c-met dimerization, and uses thereof
|
|
CA2700815A1
(en)
|
2007-09-27 |
2009-04-02 |
Viventia Biotech Inc. |
Optimized nucleic acid sequences for the expression of vb4-845
|
|
EP2220121B1
(en)
|
2007-11-12 |
2015-08-19 |
U3 Pharma GmbH |
Axl antibodies
|
|
CL2008003449A1
(es)
|
2007-11-21 |
2010-02-19 |
Imclone Llc |
Anticuerpo o fragmentos del mismo contra el receptor de proteína estimulante de macrófagos/ron; composición farmacéutica que lo comprende; uso para inhibir angiogénesis, crecimiento tumoral, proliferación, migración e invasión de células tumorales, activación de ron o fosforilación de mapk y/o akt; y uso para tratar cáncer.
|
|
PT2235064E
(pt)
|
2008-01-07 |
2016-03-01 |
Amgen Inc |
Método de preparação de moléculas heterodiméricas de fc de anticorpos utilizando efeitos de indução eletrostática
|
|
BRPI0906498A2
(pt)
|
2008-01-22 |
2015-07-14 |
Biogen Idec Inc |
Anticorpo ron e seus usos
|
|
MX2010011145A
(es)
*
|
2008-04-11 |
2011-04-11 |
Merrimack Pharmaceuticals Inc |
Enlazadores de la albumina de suero humana y conjugados de la misma.
|
|
US20100009390A1
(en)
|
2008-05-09 |
2010-01-14 |
The Regents Of The University Of California |
Mutant antibodies with high affinity for egfr
|
|
WO2010002862A2
(en)
|
2008-07-01 |
2010-01-07 |
Aveo Pharmaceuticals, Inc. |
Fibroblast growth factor receptor 3 (fgfr3) binding proteins
|
|
WO2010064090A1
(en)
|
2008-12-02 |
2010-06-10 |
Pierre Fabre Medicament |
Process for the modulation of the antagonistic activity of a monoclonal antibody
|
|
MX2011010158A
(es)
|
2009-04-07 |
2011-10-17 |
Roche Glycart Ag |
Anticuerpos biespecificos anti-erbb-2/anti-c-met.
|
|
MX2011012136A
(es)
|
2009-05-15 |
2012-04-10 |
Chugai Pharmaceutical Co Ltd |
Anticuerpo anti-axl.
|
|
GB0909904D0
(en)
*
|
2009-06-09 |
2009-07-22 |
Affitech As |
Product
|
|
US9493578B2
(en)
*
|
2009-09-02 |
2016-11-15 |
Xencor, Inc. |
Compositions and methods for simultaneous bivalent and monovalent co-engagement of antigens
|
|
TWI600760B
(zh)
|
2009-11-05 |
2017-10-01 |
建南德克公司 |
分泌異源多肽之方法及組合物
|
|
RS66008B1
(sr)
|
2010-03-10 |
2024-10-31 |
Genmab As |
Monoklonska antitela protiv c-met
|
|
WO2011136911A2
(en)
|
2010-04-09 |
2011-11-03 |
Aveo Pharmaceuticals, Inc. |
Anti-erbb3 antibodies
|
|
SG185487A1
(en)
|
2010-05-11 |
2012-12-28 |
Aveo Pharmaceuticals Inc |
Anti-fgfr2 antibodies
|
|
WO2011159980A1
(en)
|
2010-06-18 |
2011-12-22 |
Genentech, Inc. |
Anti-axl antibodies and methods of use
|
|
CA2804399A1
(en)
|
2010-07-06 |
2012-01-12 |
Aveo Pharmaceuticals, Inc. |
Anti-ron antibodies
|
|
WO2012006635A1
(en)
|
2010-07-09 |
2012-01-12 |
Biogen Idec Hemophilia Inc. |
Processable single chain molecules and polypeptides made using same
|
|
WO2013033008A2
(en)
|
2011-08-26 |
2013-03-07 |
Merrimack Pharmaceuticals, Inc. |
Tandem fc bispecific antibodies
|
|
MX2015011712A
(es)
*
|
2013-03-06 |
2016-04-04 |
Merrimack Pharmaceuticals Inc |
Anticerpos biespecificos fc en fila anti-c-met.
|