|
EP0307434B2
(en)
|
1987-03-18 |
1998-07-29 |
Scotgen Biopharmaceuticals, Inc. |
Altered antibodies
|
|
US5892019A
(en)
|
1987-07-15 |
1999-04-06 |
The United States Of America, As Represented By The Department Of Health And Human Services |
Production of a single-gene-encoded immunoglobulin
|
|
US5468468A
(en)
|
1989-02-09 |
1995-11-21 |
The United States Of America, As Represented By The Secretary Of The Department Of Health & Human Services |
Method for making a monoclonal antibody, monoclonal antibodies to α PD
|
|
DE4205148A1
(de)
|
1991-05-25 |
1993-01-21 |
Boehringer Mannheim Gmbh |
Monoklonale antikoerper gegen c-kit
|
|
ATE255131T1
(de)
|
1991-06-14 |
2003-12-15 |
Genentech Inc |
Humanisierter heregulin antikörper
|
|
US6696548B2
(en)
|
1993-12-03 |
2004-02-24 |
St. Jude Children's Research Hospital |
Antibodies for recognition of alk protein tyrosine/kinase receptor
|
|
US5731168A
(en)
|
1995-03-01 |
1998-03-24 |
Genentech, Inc. |
Method for making heteromultimeric polypeptides
|
|
US5686292A
(en)
|
1995-06-02 |
1997-11-11 |
Genentech, Inc. |
Hepatocyte growth factor receptor antagonist antibodies and uses thereof
|
|
DE19638745C2
(de)
|
1996-09-11 |
2001-05-10 |
Schering Ag |
Monoklonale Antikörper gegen die extrazelluläre Domäne des menschlichen VEGF - Rezeptorproteins (KDR)
|
|
US20020062010A1
(en)
|
1997-05-02 |
2002-05-23 |
Genentech, Inc. |
Method for making multispecific antibodies having heteromultimeric and common components
|
|
US6235883B1
(en)
|
1997-05-05 |
2001-05-22 |
Abgenix, Inc. |
Human monoclonal antibodies to epidermal growth factor receptor
|
|
US20020136721A1
(en)
*
|
1998-02-17 |
2002-09-26 |
Schwall Ralph H. |
Hepatocyte growth factor receptor antagonists and uses thereof
|
|
AU3657899A
(en)
|
1998-04-20 |
1999-11-08 |
James E. Bailey |
Glycosylation engineering of antibodies for improving antibody-dependent cellular cytotoxicity
|
|
PT1176195E
(pt)
|
1999-04-09 |
2013-07-18 |
Kyowa Hakko Kirin Co Ltd |
Processo para controlar a actividade de uma molécula funcional sob o ponto de vista imunológico
|
|
AU5286999A
(en)
|
1999-07-23 |
2001-02-13 |
Glaxo Group Limited |
Combination of an anti-ep-cam antibody with a chemotherapeutic agent
|
|
US8071072B2
(en)
|
1999-10-08 |
2011-12-06 |
Hoffmann-La Roche Inc. |
Cytotoxicity mediation of cells evidencing surface expression of CD44
|
|
CA2388245C
(en)
|
1999-10-19 |
2012-01-10 |
Kyowa Kirin Co., Ltd. |
The use of serum-free adapted rat cells for producing heterologous polypeptides
|
|
JP4132547B2
(ja)
|
2000-03-01 |
2008-08-13 |
富士フイルム株式会社 |
画像形成材料及びそれを用いた平版印刷版原版
|
|
US20020119148A1
(en)
|
2000-09-01 |
2002-08-29 |
Gerritsen Mary E. |
ErbB4 antagonists
|
|
US7101976B1
(en)
|
2000-09-12 |
2006-09-05 |
Purdue Research Foundation |
EphA2 monoclonal antibodies and methods of making and using same
|
|
WO2002030954A1
(en)
|
2000-10-06 |
2002-04-18 |
Kyowa Hakko Kogyo Co., Ltd. |
Method of purifying antibody
|
|
DK2314686T4
(da)
|
2000-10-06 |
2023-08-21 |
Kyowa Kirin Co Ltd |
Celler, der danner antistofsammensætninger
|
|
PA8535501A1
(es)
|
2001-01-05 |
2003-07-28 |
Pfizer |
Anticuerpos contra el receptor del factor de crecimiento similar a insulina
|
|
AU2002307037B2
(en)
|
2001-04-02 |
2008-08-07 |
Biogen Idec Inc. |
Recombinant antibodies coexpressed with GnTIII
|
|
KR100900166B1
(ko)
|
2001-05-03 |
2009-06-02 |
메르크 파텐트 게엠베하 |
재조합 종양 특이적 항체 및 이들의 용도
|
|
US6972324B2
(en)
|
2001-05-18 |
2005-12-06 |
Boehringer Ingelheim Pharmaceuticals, Inc. |
Antibodies specific for CD44v6
|
|
CA2450793A1
(en)
|
2001-06-20 |
2002-12-27 |
Prochon Biotech Ltd. |
Antibodies that block receptor protein tyrosine kinase activation, methods of screening for and uses thereof
|
|
CA2453662A1
(en)
|
2001-07-19 |
2003-01-30 |
Stefan Ewert |
Modification of human variable domains
|
|
KR100988949B1
(ko)
|
2001-10-25 |
2010-10-20 |
제넨테크, 인크. |
당단백질 조성물
|
|
JP2005530687A
(ja)
|
2002-01-31 |
2005-10-13 |
マックス−プランク−ゲゼルシャフト・ツア・フェルデルング・デア・ヴィッセンシャフテン・エー・ファオ |
Ｆｇｆｒアゴニスト
|
|
US7498414B2
(en)
|
2002-03-04 |
2009-03-03 |
Imclone Systems Incorporated |
Human antibodies specific to KDR and uses thereof
|
|
EP1575509B1
(en)
|
2002-05-10 |
2011-10-26 |
Purdue Research Foundation |
Epha2 agonistic monoclonal antibodies and methods of use thereof
|
|
US20080008713A1
(en)
|
2002-06-28 |
2008-01-10 |
Domantis Limited |
Single domain antibodies against tnfr1 and methods of use therefor
|
|
US7232888B2
(en)
|
2002-07-01 |
2007-06-19 |
Massachusetts Institute Of Technology |
Antibodies against tumor surface antigens
|
|
EP1592713A2
(en)
|
2003-02-13 |
2005-11-09 |
Pharmacia Corporation |
Antibodies to c-met for the treatment of cancers
|
|
ITMI20031127A1
(it)
|
2003-06-05 |
2004-12-06 |
Uni Degli Studi Del Piemont E Orientale Am |
Anticorpi anti-hgf-r e loro uso
|
|
HN2004000285A
(es)
|
2003-08-04 |
2006-04-27 |
Pfizer Prod Inc |
ANTICUERPOS DIRIGIDOS A c-MET
|
|
CN1871259A
(zh)
|
2003-08-22 |
2006-11-29 |
比奥根艾迪克Ma公司 |
具有改变的效应物功能的经改进的抗体和制备它的方法
|
|
EP2060270A3
(en)
|
2003-10-16 |
2009-12-09 |
Imclone LLC |
Fibroblast growth factor receptor-1 inhibitors and methods of treatment thereof
|
|
WO2005063815A2
(en)
|
2003-11-12 |
2005-07-14 |
Biogen Idec Ma Inc. |
Fcϝ receptor-binding polypeptide variants and methods related thereto
|
|
EP2385069A3
(en)
|
2003-11-12 |
2012-05-30 |
Biogen Idec MA Inc. |
Neonatal Fc rReceptor (FcRn)- binding polypeptide variants, dimeric Fc binding proteins and methods related thereto
|
|
AU2004309347B2
(en)
|
2003-12-19 |
2010-03-04 |
Genentech, Inc. |
Monovalent antibody fragments useful as therapeutics
|
|
HRP20141111T1
(hr)
|
2004-07-22 |
2015-01-02 |
Genentech, Inc. |
Sastav her2-protutijela
|
|
PT1773885E
(pt)
|
2004-08-05 |
2010-07-21 |
Genentech Inc |
Antagonistas anti-cmet humanizados
|
|
MY146381A
(en)
|
2004-12-22 |
2012-08-15 |
Amgen Inc |
Compositions and methods relating relating to anti-igf-1 receptor antibodies
|
|
KR101363252B1
(ko)
|
2005-02-04 |
2014-02-13 |
레이븐 바이오테크놀로지스, 인코퍼레이티드 |
Ｅｐｈａ2에 결합하는 항체 및 그것의 사용방법
|
|
ES2755976T3
(es)
|
2005-02-07 |
2020-04-24 |
Roche Glycart Ag |
Moléculas de unión a antígeno que se unen a EGFR, vectores que las codifican y usos de las mismas
|
|
CN101184506B
(zh)
|
2005-03-25 |
2013-07-17 |
健泰科生物技术公司 |
用于调节超稳定化的c-met的方法和组合物
|
|
JP2008539753A
(ja)
|
2005-05-09 |
2008-11-20 |
グリクアート バイオテクノロジー アクチェンゲゼルシャフト |
修飾ｆｃ領域およびｆｃ受容体との結合変更を有する抗原結合分子
|
|
KR101246504B1
(ko)
|
2005-06-17 |
2013-03-26 |
임클론 엘엘씨 |
항－ＰＤＧＦＲα 항체
|
|
AR056857A1
(es)
|
2005-12-30 |
2007-10-24 |
U3 Pharma Ag |
Anticuerpos dirigidos hacia her-3 (receptor del factor de crecimiento epidérmico humano-3) y sus usos
|
|
US7976842B2
(en)
|
2006-02-09 |
2011-07-12 |
Micromet Ag |
Treatment of metastatic breast cancer
|
|
CN103073639A
(zh)
|
2006-03-17 |
2013-05-01 |
比奥根艾迪克Ma公司 |
稳定的多肽组合物
|
|
CL2007000851A1
(es)
|
2006-03-30 |
2008-03-14 |
Novartis Ag |
Anticuerpo anti receptor del factor de crecimiento del hepatocito (c-met); adn que codifican cadenas livianas y pesadas del anticuerpo; composicion farmaceutica y kit que comprenden dicho anticuerpo; metodo para tratar trastorno relacionado con c-met
|
|
TWI395754B
(zh)
|
2006-04-24 |
2013-05-11 |
Amgen Inc |
人類化之ｃ-ｋｉｔ抗體
|
|
EP2013236B1
(en)
|
2006-04-28 |
2015-06-17 |
Delenex Therapeutics AG |
Antibodies binding to the extracellular domain of the receptor tyrosine kinase alk
|
|
US8394927B2
(en)
|
2006-11-03 |
2013-03-12 |
U3 Pharma Gmbh |
FGFR4 antibodies
|
|
UY30776A1
(es)
|
2006-12-21 |
2008-07-03 |
Medarex Inc |
Anticuerpos cd44
|
|
SG178789A1
(en)
|
2007-02-16 |
2012-03-29 |
Merrimack Pharmaceuticals Inc |
Antibodies against erbb3 and uses thereof
|
|
ATE514714T1
(de)
|
2007-03-19 |
2011-07-15 |
Univ Stuttgart |
Hutnfr1-selektive antagonisten
|
|
CA2682390A1
(en)
|
2007-04-17 |
2008-10-30 |
Imclone Llc |
Pdgfr.beta.-specific inhibitors
|
|
CA2682605A1
(en)
*
|
2007-04-18 |
2008-10-30 |
Zymogenetics, Inc. |
Single chain fc, methods of making and methods of treatment
|
|
WO2008131575A2
(en)
|
2007-04-27 |
2008-11-06 |
Esbatech Ag |
Anti-alk antibodies suitable for treating metastatic cancers or tumors
|
|
EP2158318A2
(en)
*
|
2007-05-14 |
2010-03-03 |
Biogen Idec MA, Inc. |
Single-chain fc (scfc) regions, binding polypeptides comprising same, and methods related thereto
|
|
EP2014681A1
(en)
|
2007-07-12 |
2009-01-14 |
Pierre Fabre Medicament |
Novel antibodies inhibiting c-met dimerization, and uses thereof
|
|
CA2700815A1
(en)
*
|
2007-09-27 |
2009-04-02 |
Viventia Biotech Inc. |
Optimized nucleic acid sequences for the expression of vb4-845
|
|
CA2705164A1
(en)
|
2007-11-12 |
2009-05-22 |
U3 Pharma Gmbh |
Axl antibodies
|
|
AR069393A1
(es)
|
2007-11-21 |
2010-01-20 |
Imclone Systems Inc |
Inhibicion del receptor para la proteina estimulante del macrofago (ron) y metodos para el tratamiento del mismo
|
|
EP3663318A1
(en)
|
2008-01-07 |
2020-06-10 |
Amgen Inc. |
Method for making antibody fc-heterodimeric molecules using electrostatic steering effects
|
|
JP2011509687A
(ja)
|
2008-01-22 |
2011-03-31 |
バイオジェン・アイデック・エムエイ・インコーポレイテッド |
Ｒｏｎ抗体およびその使用
|
|
BRPI0911652A2
(pt)
*
|
2008-04-11 |
2015-08-04 |
Merrimack Pharmaceuticals Inc |
Ligantes de albumina sérica humana e seus conjugados
|
|
US20100009390A1
(en)
|
2008-05-09 |
2010-01-14 |
The Regents Of The University Of California |
Mutant antibodies with high affinity for egfr
|
|
US8187601B2
(en)
|
2008-07-01 |
2012-05-29 |
Aveo Pharmaceuticals, Inc. |
Fibroblast growth factor receptor 3 (FGFR3) binding proteins
|
|
WO2010064090A1
(en)
|
2008-12-02 |
2010-06-10 |
Pierre Fabre Medicament |
Process for the modulation of the antagonistic activity of a monoclonal antibody
|
|
AU2010233993A1
(en)
|
2009-04-07 |
2011-09-08 |
Roche Glycart Ag |
Bispecific anti-ErbB-1/anti-c-Met antibodies
|
|
RU2011151069A
(ru)
|
2009-05-15 |
2013-06-20 |
Чугаи Сейяку Кабусики Кайся |
Анти-axl антитело
|
|
GB0909904D0
(en)
*
|
2009-06-09 |
2009-07-22 |
Affitech As |
Product
|
|
WO2011028952A1
(en)
|
2009-09-02 |
2011-03-10 |
Xencor, Inc. |
Compositions and methods for simultaneous bivalent and monovalent co-engagement of antigens
|
|
SI2496601T1
(sl)
|
2009-11-05 |
2017-09-29 |
F. Hoffmann-La Roche Ag |
Tehnike in sestavek za sekrecijo heterolognih polipeptidov
|
|
WO2011110642A2
(en)
|
2010-03-10 |
2011-09-15 |
Genmab A/S |
Monoclonal antibodies against c-met
|
|
US8481687B2
(en)
|
2010-04-09 |
2013-07-09 |
Aveo Pharmaceuticals, Inc. |
Anti-ErbB3 antibodies
|
|
US8481688B2
(en)
|
2010-05-11 |
2013-07-09 |
Aveo Pharmaceuticals, Inc. |
Anti-FGFR2 antibodies
|
|
CA2794731C
(en)
|
2010-06-18 |
2019-03-19 |
Genentech, Inc. |
Anti-axl antibodies and methods of use
|
|
US8603478B2
(en)
|
2010-07-06 |
2013-12-10 |
Aveo Pharmaceuticals, Inc. |
Anti-RON antibodies
|
|
HRP20191305T1
(hr)
|
2010-07-09 |
2019-10-18 |
Bioverativ Therapeutics Inc. |
Preradive jednolančane molekule i polipeptidi izrađeni koristeći iste
|
|
CN103857700A
(zh)
|
2011-08-26 |
2014-06-11 |
梅里麦克制药股份有限公司 |
串联fc双特异性抗体
|
|
CA2902505A1
(en)
*
|
2013-03-06 |
2014-09-12 |
Merrimack Pharmaceuticals, Inc. |
Anti-c-met tandem fc bispecific antibodies
|