|
JP3101690B2
(ja)
|
1987-03-18 |
2000-10-23 |
エス・ビィ・２・インコーポレイテッド |
変性抗体の、または変性抗体に関する改良
|
|
US5892019A
(en)
|
1987-07-15 |
1999-04-06 |
The United States Of America, As Represented By The Department Of Health And Human Services |
Production of a single-gene-encoded immunoglobulin
|
|
US5468468A
(en)
|
1989-02-09 |
1995-11-21 |
The United States Of America, As Represented By The Secretary Of The Department Of Health & Human Services |
Method for making a monoclonal antibody, monoclonal antibodies to α PD
|
|
DE4205148A1
(de)
|
1991-05-25 |
1993-01-21 |
Boehringer Mannheim Gmbh |
Monoklonale antikoerper gegen c-kit
|
|
EP0590058B1
(en)
|
1991-06-14 |
2003-11-26 |
Genentech, Inc. |
HUMANIZED Heregulin ANTIBODy
|
|
US6696548B2
(en)
|
1993-12-03 |
2004-02-24 |
St. Jude Children's Research Hospital |
Antibodies for recognition of alk protein tyrosine/kinase receptor
|
|
US5731168A
(en)
|
1995-03-01 |
1998-03-24 |
Genentech, Inc. |
Method for making heteromultimeric polypeptides
|
|
US5686292A
(en)
|
1995-06-02 |
1997-11-11 |
Genentech, Inc. |
Hepatocyte growth factor receptor antagonist antibodies and uses thereof
|
|
DE19638745C2
(de)
|
1996-09-11 |
2001-05-10 |
Schering Ag |
Monoklonale Antikörper gegen die extrazelluläre Domäne des menschlichen VEGF - Rezeptorproteins (KDR)
|
|
US20020062010A1
(en)
|
1997-05-02 |
2002-05-23 |
Genentech, Inc. |
Method for making multispecific antibodies having heteromultimeric and common components
|
|
US6235883B1
(en)
|
1997-05-05 |
2001-05-22 |
Abgenix, Inc. |
Human monoclonal antibodies to epidermal growth factor receptor
|
|
US20020136721A1
(en)
*
|
1998-02-17 |
2002-09-26 |
Schwall Ralph H. |
Hepatocyte growth factor receptor antagonists and uses thereof
|
|
JP4334141B2
(ja)
|
1998-04-20 |
2009-09-30 |
グリカート バイオテクノロジー アクチェンゲゼルシャフト |
抗体依存性細胞傷害性を改善するための抗体のグリコシル化操作
|
|
EP2275540B1
(en)
|
1999-04-09 |
2016-03-23 |
Kyowa Hakko Kirin Co., Ltd. |
Method for controlling the activity of immunologically functional molecule
|
|
WO2001007082A1
(en)
|
1999-07-23 |
2001-02-01 |
Glaxo Group Limited |
Combination of an anti-ep-cam antibody with a chemotherapeutic agent
|
|
US8071072B2
(en)
|
1999-10-08 |
2011-12-06 |
Hoffmann-La Roche Inc. |
Cytotoxicity mediation of cells evidencing surface expression of CD44
|
|
CA2388245C
(en)
|
1999-10-19 |
2012-01-10 |
Kyowa Kirin Co., Ltd. |
The use of serum-free adapted rat cells for producing heterologous polypeptides
|
|
JP4132547B2
(ja)
|
2000-03-01 |
2008-08-13 |
富士フイルム株式会社 |
画像形成材料及びそれを用いた平版印刷版原版
|
|
US20020119148A1
(en)
|
2000-09-01 |
2002-08-29 |
Gerritsen Mary E. |
ErbB4 antagonists
|
|
US7101976B1
(en)
|
2000-09-12 |
2006-09-05 |
Purdue Research Foundation |
EphA2 monoclonal antibodies and methods of making and using same
|
|
JPWO2002030954A1
(ja)
|
2000-10-06 |
2004-02-19 |
協和醗酵工業株式会社 |
抗体を精製する方法
|
|
CN103333860B
(zh)
|
2000-10-06 |
2015-07-08 |
协和发酵麒麟株式会社 |
产生抗体组合物的细胞
|
|
NZ527302A
(en)
|
2001-01-05 |
2006-10-27 |
Abgenix Inc |
Antibodies to insulin-like growth factor I receptor
|
|
EP1383800A4
(en)
|
2001-04-02 |
2004-09-22 |
Idec Pharma Corp |
RECOMBINANT ANTIBODIES CO-EXPRESSED WITH GNTIII
|
|
BR0209177A
(pt)
|
2001-05-03 |
2004-10-05 |
Merck Patent Gmbh |
Anticorpo especìfico a tumor recombinante e uso do mesmo
|
|
US6972324B2
(en)
|
2001-05-18 |
2005-12-06 |
Boehringer Ingelheim Pharmaceuticals, Inc. |
Antibodies specific for CD44v6
|
|
IL159177A0
(en)
|
2001-06-20 |
2004-06-01 |
Prochon Biotech Ltd |
Antibodies that block receptor protein tyrosine kinase activation, methods of screening for and uses thereof
|
|
JP4355571B2
(ja)
|
2001-07-19 |
2009-11-04 |
ウニベルジテート チューリッヒ |
ヒト可変ドメインの改変
|
|
PL213948B1
(pl)
|
2001-10-25 |
2013-05-31 |
Genentech Inc |
Kompozycje zawierajace glikoproteine, czasteczka kwasu nukleinowego kodujaca te glikoproteine, komórka gospodarza, sposób wytwarzania glikoproteiny, kompozycja do zastosowania do leczenia, zastosowanie kompozycji i zestaw zawierajacy kompozycje
|
|
ES2363765T3
(es)
|
2002-01-31 |
2011-08-16 |
MAX-PLANCK-Gesellschaft zur Förderung der Wissenschaften e.V. |
Agonistas de fgfr.
|
|
PT1916001E
(pt)
|
2002-03-04 |
2011-07-18 |
Imclone Llc |
Anticorpos humanos específicos para kdr e suas utilizações
|
|
EP1575509B1
(en)
|
2002-05-10 |
2011-10-26 |
Purdue Research Foundation |
Epha2 agonistic monoclonal antibodies and methods of use thereof
|
|
US20080008713A1
(en)
|
2002-06-28 |
2008-01-10 |
Domantis Limited |
Single domain antibodies against tnfr1 and methods of use therefor
|
|
US7232888B2
(en)
|
2002-07-01 |
2007-06-19 |
Massachusetts Institute Of Technology |
Antibodies against tumor surface antigens
|
|
MXPA05008521A
(es)
|
2003-02-13 |
2005-10-20 |
Pharmacia Corp |
Anticuerpos a c-met para el tratamiento de canceres.
|
|
ITMI20031127A1
(it)
|
2003-06-05 |
2004-12-06 |
Uni Degli Studi Del Piemont E Orientale Am |
Anticorpi anti-hgf-r e loro uso
|
|
HN2004000285A
(es)
|
2003-08-04 |
2006-04-27 |
Pfizer Prod Inc |
ANTICUERPOS DIRIGIDOS A c-MET
|
|
AU2004266159A1
(en)
|
2003-08-22 |
2005-03-03 |
Biogen Idec Ma Inc. |
Improved antibodies having altered effector function and methods for making the same
|
|
SI1680140T1
(sl)
|
2003-10-16 |
2011-08-31 |
Imclone Llc |
Inhibitorji receptorja-1 za fibroblastni rastni faktor in metode za zdravljenje z le-temi
|
|
WO2005047327A2
(en)
|
2003-11-12 |
2005-05-26 |
Biogen Idec Ma Inc. |
NEONATAL Fc RECEPTOR (FcRn)-BINDING POLYPEPTIDE VARIANTS, DIMERIC Fc BINDING PROTEINS AND METHODS RELATED THERETO
|
|
WO2005063815A2
(en)
|
2003-11-12 |
2005-07-14 |
Biogen Idec Ma Inc. |
Fcϝ receptor-binding polypeptide variants and methods related thereto
|
|
PT1718677E
(pt)
|
2003-12-19 |
2012-07-18 |
Genentech Inc |
Fragmentos de anticorpo monovalentes úteis como agentes terapêuticos
|
|
UA90480C2
(uk)
|
2004-07-22 |
2010-05-11 |
Джэнэнтэк, Инк. |
Фармацевтична композиція, що має протипухлинну активність, яка включає антитіло до her2
|
|
ME01803B
(me)
|
2004-08-05 |
2010-12-31 |
Genentech Inc |
Humanizovani anti-cmet antagonisti
|
|
MY146381A
(en)
|
2004-12-22 |
2012-08-15 |
Amgen Inc |
Compositions and methods relating relating to anti-igf-1 receptor antibodies
|
|
BRPI0607450A2
(pt)
|
2005-02-04 |
2009-09-01 |
Raven Biotechnologies Inc |
anticorpos que se ligam a epha2 e métodos para sua utilização
|
|
BRPI0607315B1
(pt)
|
2005-02-07 |
2022-05-17 |
Roche Glycart Ag |
Molécula de ligação ao antígeno anti-egfr humanizada e seus usos, composição farmacêutica, e método para detectar a presença de egfr em uma amostra
|
|
US7615529B2
(en)
|
2005-03-25 |
2009-11-10 |
Genentech, Inc. |
Methods and compositions for modulating hyperstabilized c-met
|
|
EP1888649A2
(en)
|
2005-05-09 |
2008-02-20 |
GlycArt Biotechnology AG |
Antigen binding molecules having modified fc regions and altered binding to fc receptors
|
|
CA2678008C
(en)
|
2005-06-17 |
2013-07-30 |
Imclone Systems Incorporated |
Methods of treating a secondary bone tumor with anti-pdgfralpha antibodies
|
|
AR056857A1
(es)
|
2005-12-30 |
2007-10-24 |
U3 Pharma Ag |
Anticuerpos dirigidos hacia her-3 (receptor del factor de crecimiento epidérmico humano-3) y sus usos
|
|
RU2434640C2
(ru)
|
2006-02-09 |
2011-11-27 |
Микромет Аг |
Лечение метастатического рака молочной железы
|
|
EA015992B1
(ru)
|
2006-03-17 |
2012-01-30 |
Байоджен Айдек Эмэй Инк. |
Стабилизированное антитело и многовалентная антигенсвязывающая молекула на его основе, способы получения и использования вышеназванного стабилизированного антитела
|
|
BRPI0709917A2
(pt)
|
2006-03-30 |
2011-07-05 |
Novartis Ag |
composições e métodos de uso para anticorpos de c-met
|
|
TWI395754B
(zh)
|
2006-04-24 |
2013-05-11 |
Amgen Inc |
人類化之ｃ-ｋｉｔ抗體
|
|
CA2650822C
(en)
|
2006-04-28 |
2017-03-14 |
Esbatech Ag |
Antibodies binding to the extracellular domain of the receptor tyrosine kinase alk
|
|
EP2094733A1
(en)
|
2006-11-03 |
2009-09-02 |
U3 Pharma GmbH |
Fgfr4 antibodies
|
|
UY30776A1
(es)
|
2006-12-21 |
2008-07-03 |
Medarex Inc |
Anticuerpos cd44
|
|
NZ579644A
(en)
|
2007-02-16 |
2012-05-25 |
Merrimack Pharmaceuticals Inc |
Antibodies against erbb3 and uses thereof
|
|
PL1972637T3
(pl)
|
2007-03-19 |
2012-01-31 |
Univ Stuttgart |
Antagoniści selektywni wobec huTNFR1
|
|
EA019595B1
(ru)
|
2007-04-17 |
2014-04-30 |
Имклоун Элэлси |
СПЕЦИФИЧНЫЕ ИНГИБИТОРЫ PDGFRβ
|
|
CA2682605A1
(en)
*
|
2007-04-18 |
2008-10-30 |
Zymogenetics, Inc. |
Single chain fc, methods of making and methods of treatment
|
|
WO2008131575A2
(en)
|
2007-04-27 |
2008-11-06 |
Esbatech Ag |
Anti-alk antibodies suitable for treating metastatic cancers or tumors
|
|
MX2009012343A
(es)
*
|
2007-05-14 |
2010-02-10 |
Biogen Idec Inc |
Regiones fc (sc fc) de cadena sencilla, polipeptidos de enlace que comprenden las mismas, y metodos relacionados con ello.
|
|
EP2014681A1
(en)
|
2007-07-12 |
2009-01-14 |
Pierre Fabre Medicament |
Novel antibodies inhibiting c-met dimerization, and uses thereof
|
|
CA2700815A1
(en)
|
2007-09-27 |
2009-04-02 |
Viventia Biotech Inc. |
Optimized nucleic acid sequences for the expression of vb4-845
|
|
BRPI0820073A2
(pt)
|
2007-11-12 |
2015-06-23 |
U3 Pharma Gmbh |
Anticorpos anti-axl
|
|
UY31478A1
(es)
|
2007-11-21 |
2009-07-17 |
|
Inhibicion del receptor para la proteina estimulante del macrofago (ron) y métodos para el tratamiento de lo mismo
|
|
EP3663318A1
(en)
|
2008-01-07 |
2020-06-10 |
Amgen Inc. |
Method for making antibody fc-heterodimeric molecules using electrostatic steering effects
|
|
US20090226442A1
(en)
|
2008-01-22 |
2009-09-10 |
Biogen Idec Ma Inc. |
RON antibodies and uses thereof
|
|
JP5639039B2
(ja)
*
|
2008-04-11 |
2014-12-10 |
メリマック ファーマシューティカルズ インコーポレーティッド |
ヒト血清アルブミンリンカーおよびそのコンジュゲート
|
|
US20100009390A1
(en)
|
2008-05-09 |
2010-01-14 |
The Regents Of The University Of California |
Mutant antibodies with high affinity for egfr
|
|
WO2010002862A2
(en)
|
2008-07-01 |
2010-01-07 |
Aveo Pharmaceuticals, Inc. |
Fibroblast growth factor receptor 3 (fgfr3) binding proteins
|
|
WO2010064090A1
(en)
|
2008-12-02 |
2010-06-10 |
Pierre Fabre Medicament |
Process for the modulation of the antagonistic activity of a monoclonal antibody
|
|
CN102361884A
(zh)
|
2009-04-07 |
2012-02-22 |
罗氏格黎卡特股份公司 |
双特异性抗-ErbB-2/抗-c-Met抗体
|
|
CN102459344A
(zh)
|
2009-05-15 |
2012-05-16 |
中外制药株式会社 |
抗axl抗体
|
|
GB0909904D0
(en)
*
|
2009-06-09 |
2009-07-22 |
Affitech As |
Product
|
|
US9493578B2
(en)
|
2009-09-02 |
2016-11-15 |
Xencor, Inc. |
Compositions and methods for simultaneous bivalent and monovalent co-engagement of antigens
|
|
KR101968766B1
(ko)
|
2009-11-05 |
2019-04-12 |
제넨테크, 인크. |
이종 폴리펩티드의 분비를 위한 방법 및 조성물
|
|
EP3904391B1
(en)
|
2010-03-10 |
2024-07-10 |
Genmab A/S |
Monoclonal antibodies against c-met
|
|
KR101764453B1
(ko)
|
2010-04-09 |
2017-08-02 |
아베오 파마슈티컬즈, 인크. |
항-erbb3 항체
|
|
CA2800311A1
(en)
|
2010-05-11 |
2011-11-17 |
Aveo Pharmaceuticals, Inc. |
Anti-fgfr2 antibodies
|
|
CN103080136B
(zh)
|
2010-06-18 |
2015-08-12 |
霍夫曼-拉罗奇有限公司 |
抗Axl抗体及使用方法
|
|
JP2013533746A
(ja)
|
2010-07-06 |
2013-08-29 |
アベオ ファーマシューティカルズ， インコーポレイテッド |
抗ｒｏｎ抗体
|
|
PT2591006T
(pt)
|
2010-07-09 |
2019-07-29 |
Bioverativ Therapeutics Inc |
Moléculas de cadeia simples processáveis e polipéptidos preparados utilizando as mesmas
|
|
WO2013033008A2
(en)
|
2011-08-26 |
2013-03-07 |
Merrimack Pharmaceuticals, Inc. |
Tandem fc bispecific antibodies
|
|
SG11201506451UA
(en)
*
|
2013-03-06 |
2015-09-29 |
Merrimack Pharmaceuticals Inc |
Anti-c-met tandem fc bispecific antibodies
|