JP2016506391A5 - - Google Patents
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- Publication number
- JP2016506391A5 JP2016506391A5 JP2015546449A JP2015546449A JP2016506391A5 JP 2016506391 A5 JP2016506391 A5 JP 2016506391A5 JP 2015546449 A JP2015546449 A JP 2015546449A JP 2015546449 A JP2015546449 A JP 2015546449A JP 2016506391 A5 JP2016506391 A5 JP 2016506391A5
- Authority
- JP
- Japan
- Prior art keywords
- composition
- disease
- use according
- subject
- insulin resistance
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201261734293P | 2012-12-06 | 2012-12-06 | |
| US61/734,293 | 2012-12-06 | ||
| PCT/US2013/036214 WO2014088631A1 (en) | 2012-12-06 | 2013-04-11 | Peptide therapeutics and methods for using same |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2017146044A Division JP2018021033A (ja) | 2012-12-06 | 2017-07-28 | ペプチド治療薬およびその使用方法 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2016506391A JP2016506391A (ja) | 2016-03-03 |
| JP2016506391A5 true JP2016506391A5 (enExample) | 2016-06-02 |
Family
ID=49549068
Family Applications (3)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2015546449A Pending JP2016506391A (ja) | 2012-12-06 | 2013-04-11 | ペプチド治療薬およびその使用方法 |
| JP2017146044A Pending JP2018021033A (ja) | 2012-12-06 | 2017-07-28 | ペプチド治療薬およびその使用方法 |
| JP2018208926A Pending JP2019069942A (ja) | 2012-12-06 | 2018-11-06 | ペプチド治療薬およびその使用方法 |
Family Applications After (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2017146044A Pending JP2018021033A (ja) | 2012-12-06 | 2017-07-28 | ペプチド治療薬およびその使用方法 |
| JP2018208926A Pending JP2019069942A (ja) | 2012-12-06 | 2018-11-06 | ペプチド治療薬およびその使用方法 |
Country Status (7)
| Country | Link |
|---|---|
| US (3) | US20130303436A1 (enExample) |
| EP (3) | EP3459598A1 (enExample) |
| JP (3) | JP2016506391A (enExample) |
| CN (1) | CN104994912A (enExample) |
| CA (1) | CA2894182A1 (enExample) |
| HK (1) | HK1215934A1 (enExample) |
| WO (1) | WO2014088631A1 (enExample) |
Families Citing this family (49)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| ES3058737T3 (en) * | 2012-10-22 | 2026-03-12 | Stealth Biotherapeutics Inc | Treatment of left ventricular remodeling |
| WO2015057315A1 (en) * | 2013-09-04 | 2015-04-23 | Kelly Joseph Michael Lawless | Methods and systems for the detection of disease |
| WO2015089316A1 (en) * | 2013-12-12 | 2015-06-18 | Cornell University | Methods for preventing and treating oral cancers |
| KR20160098406A (ko) * | 2013-12-13 | 2016-08-18 | 메디뮨 리미티드 | 프로테아제 내성 펩티드 |
| WO2015095077A1 (en) * | 2013-12-16 | 2015-06-25 | Cornell University | Methods and compositions for treating and preventing cognitive dysfunction |
| CA2935207C (en) | 2013-12-27 | 2022-06-21 | Stealth Biotherapeutics Corp | Pharmaceutically relevant aromatic-cationic peptides |
| US20170081363A1 (en) * | 2014-03-03 | 2017-03-23 | Stealth Biotherapeutics Corp | Pharmaceutically relevant aromatic-cationic peptides |
| WO2015183970A1 (en) * | 2014-05-28 | 2015-12-03 | Stealth Peptides International, Inc. | Therapeutic compositions including flavonoid and uses thereof |
| WO2015183963A2 (en) * | 2014-05-28 | 2015-12-03 | Stealth Peptides International, Inc. | Therapeutic compositions including redox-active parabenzoquinones and uses thereof |
| CA2950410A1 (en) * | 2014-05-28 | 2015-12-03 | D. Travis Wilson | Therapeutic compositions including therapeutic small molecules and uses thereof |
| EP3501532A3 (en) * | 2014-05-28 | 2019-07-17 | Stealth BioTherapeutics Corp | Therapeutic compositions including frataxin, lactoferrin, and mitochondrial energy generating enzymes, and uses thereof |
| WO2015183984A2 (en) * | 2014-05-28 | 2015-12-03 | Stealth Peptides International, Inc. | Therapeutic compositions including tocopherol and uses thereof |
| WO2015183985A2 (en) * | 2014-05-28 | 2015-12-03 | Stealth Peptides International, Inc. | Therapeutic compositions including naphthoquinones and uses thereof |
| US10627392B2 (en) | 2014-06-17 | 2020-04-21 | Stealth Biotherapeutics Corp | Methods of identifying and monitoring mitochondrial dysfunction using monocyte screening |
| EP3182989B1 (en) | 2014-08-21 | 2021-04-14 | Stealth Biotherapeutics Corp | Peptide d-arg-2',6'-dmt-lys-phe-nh2 for treating alport syndrome |
| ES2630106T3 (es) * | 2014-10-07 | 2017-08-18 | Cyprumed Gmbh | Formulaciones farmacéuticas para la administración oral de fármacos peptídicos o proteicos |
| WO2016073829A2 (en) | 2014-11-07 | 2016-05-12 | The Johns Hopkins University | Treatment of retinitis pigmentosa with n-acetylcysteine amide |
| WO2016077422A1 (en) * | 2014-11-11 | 2016-05-19 | The Johns Hopkins University | Biomarkers useful in the treatment of subjects having retinits pigmentosa |
| US11268964B2 (en) * | 2014-11-11 | 2022-03-08 | The Johns Hopkins University | Biomarkers useful in the treatment of subjects having diseases of the eye |
| EP3265109B1 (en) | 2015-03-06 | 2020-10-21 | Stealth BioTherapeutics Corp | Processes for preparing pharmaceutically relevant peptides |
| WO2016190852A1 (en) * | 2015-05-26 | 2016-12-01 | Stealth Peptides International, Inc. | Therapeutic compositions including chromanyl compounds, variants and analogues thereof, and uses thereof |
| WO2016195663A1 (en) * | 2015-06-02 | 2016-12-08 | Stealth Peptides International, Inc. | Therapeutic compositions including bpm 31510, variants and analogues thereof, and uses thereof |
| TWI726889B (zh) * | 2015-06-10 | 2021-05-11 | 英商梅迪繆思有限公司 | 蛋白酶抗性之脂化肽 |
| EP3393496B1 (en) | 2015-12-23 | 2023-10-11 | The Johns Hopkins University | Long-acting glp-1r agonist as a therapy of neurological and neurodegenerative conditions |
| ES3057779T3 (en) | 2016-01-15 | 2026-03-04 | Childrens Medical Ct Corp | Therapeutic use of mitochondria and combined mitochondrial agents |
| WO2017180535A1 (en) | 2016-04-11 | 2017-10-19 | Carnot, Llc | Chiral peptides |
| CN105987839B (zh) * | 2016-06-03 | 2018-09-28 | 浙江世纪康大医疗科技股份有限公司 | 一种edta-柠檬酸抗原修复液 |
| US20200316159A1 (en) * | 2016-06-03 | 2020-10-08 | Jt Pharmaceuticals, Inc. | Sustained release compositions of kappa-opioid receptor agonist |
| CN105987840B (zh) * | 2016-06-03 | 2018-09-28 | 浙江世纪康大医疗科技股份有限公司 | 一种柠檬酸抗原修复液 |
| CN107042067B (zh) * | 2017-05-24 | 2019-11-08 | 天津大学 | 聚硅氧烷-金属有机框架材料杂化渗透蒸发复合膜及其制备与应用 |
| US11938172B2 (en) * | 2017-06-19 | 2024-03-26 | Talengen International Limited | Method for regulating and controlling GLP-1/GLP-1R and drug |
| EP3443980A1 (en) * | 2017-08-15 | 2019-02-20 | Ciliocure Limited | Compound for the treatment of patients with leptin-resistant obesity, bardet-biedl syndrome and other ciliopathies |
| AU2018338103B2 (en) | 2017-09-20 | 2020-07-16 | Nacuity Pharmaceuticals, Inc. | Method for preparation of N-acetyl cysteine amide and derivatives thereof |
| US11091433B2 (en) | 2017-09-20 | 2021-08-17 | Nacuity Pharmaceutials, Inc. | Method for preparation of N-acetyl cysteine amide and derivatives thereof |
| US11548851B2 (en) | 2017-09-20 | 2023-01-10 | Nacuity Pharmaceuticals, Inc. | Method for preparation of n-acetyl cysteine amide and derivatives thereof |
| US20190135741A1 (en) | 2017-11-09 | 2019-05-09 | Nacuity Pharmaceuticals, Inc. | Methods of Making Deuterium-Enriched N-acetylcysteine Amide (D-NACA) and (2R, 2R')-3,3'-Disulfanediyl BIS(2-Acetamidopropanamide) (DINACA) and Using D-NACA and DINACA to Treat Diseases Involving Oxidative Stress |
| WO2019201333A1 (zh) * | 2018-04-19 | 2019-10-24 | 杭州先为达生物科技有限公司 | Glp-1衍生物及其治疗用途 |
| WO2020146674A1 (en) | 2019-01-11 | 2020-07-16 | Nacuity Pharmaceuticals, Inc. | Treatment of age-related macular degeneration, glaucoma, and diabetic retinopathy with n-acetylicysteine amide (naca) or 2r,2r')-3-3'-disulfanediyl bis (2-acetamidopropanamide) (dinaca) |
| KR102745520B1 (ko) | 2019-01-11 | 2024-12-23 | 나쿠이티 파마슈티컬스, 인코포레이티드 | 방사선 피부염을 방지 및 치료하고 피부 라이트닝 또는 피부 화이트닝을 위한 n-아세틸시스테인 아미드(naca) 및 (2r,2r')-3,3'-디설판디일 비스(2-아세트아미도프로판아미드)(dinaca) |
| PT3986401T (pt) * | 2019-07-24 | 2026-02-03 | Stealth Biotherapeutics Inc | Composto peptidomimético (r)-2-amino-n-((s)-l-(((s)-5- amino-l-(3-benzil-1,2,4-oxadiazol-5-il)pentil)amino)-3-(4- hidroxi-2,6-dimetilfenil)-1-oxopropan-2-il)-5- guanidinopentanamida no tratamento de doenças neurodegenerativas |
| WO2022006470A1 (en) | 2020-07-01 | 2022-01-06 | Vanderbilt University | Methods of treatment for a kidney disease |
| KR102503914B1 (ko) * | 2020-09-01 | 2023-02-24 | 인제대학교 산학협력단 | 황반변성 세포모델의 제조방법 |
| US20230381281A1 (en) * | 2020-10-16 | 2023-11-30 | Hanmi Pharm. Co., Ltd. | Pharmaceutical composition comprising glucagon/glp-1/gip triple agonist or long-acting conjugate thereof for preventing or treating lupus-related diseases |
| CN112618966B (zh) * | 2020-12-18 | 2023-07-28 | 北京宏强富瑞技术有限公司 | 一种多波长激光针刺仪 |
| CN113421648B (zh) * | 2021-06-21 | 2024-04-23 | 中国科学院北京基因组研究所(国家生物信息中心) | 一种用于预测射血分数保留型心衰风险的模型 |
| CN113588375B (zh) * | 2021-08-20 | 2023-09-29 | 中科光华(西安)智能生物科技有限公司 | 一种高稳定性骨及骨肿瘤组织微阵列芯片及其制备方法 |
| CN116262134A (zh) * | 2021-12-15 | 2023-06-16 | 联邦生物科技(珠海横琴)有限公司 | 一种稳定的多剂量给药的glp-1受体激动剂的制剂及其制备方法和应用 |
| CN114480449A (zh) * | 2022-03-17 | 2022-05-13 | 天津医科大学总医院 | 布拉氏酵母菌CNCMI-745衍生蛋白Trx2及其在制备防治腹泻药物中的应用 |
| CN114949184A (zh) * | 2022-05-13 | 2022-08-30 | 华中科技大学同济医学院附属同济医院 | Glp-1代谢物在制备减轻急性肾损伤药物中的用途 |
Family Cites Families (17)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4522811A (en) | 1982-07-08 | 1985-06-11 | Syntex (U.S.A.) Inc. | Serial injection of muramyldipeptides and liposomes enhances the anti-infective activity of muramyldipeptides |
| US5858784A (en) | 1991-12-17 | 1999-01-12 | The Regents Of The University Of California | Expression of cloned genes in the lung by aerosol- and liposome-based delivery |
| US5716644A (en) | 1992-06-11 | 1998-02-10 | Alkermes, Inc. | Composition for sustained release of non-aggregated erythropoietin |
| US5674534A (en) | 1992-06-11 | 1997-10-07 | Alkermes, Inc. | Composition for sustained release of non-aggregated erythropoietin |
| US5989463A (en) | 1997-09-24 | 1999-11-23 | Alkermes Controlled Therapeutics, Inc. | Methods for fabricating polymer-based controlled release devices |
| US6245740B1 (en) | 1998-12-23 | 2001-06-12 | Amgen Inc. | Polyol:oil suspensions for the sustained release of proteins |
| WO2001066140A1 (en) | 2000-03-09 | 2001-09-13 | Genzyme Corporation | Use of tgf-beta antagonists to treat or to prevent loss of renal function |
| AU2002256092C1 (en) | 2001-04-05 | 2009-10-15 | Collagenex Pharmaceuticals, Inc. | Controlled delivery of tetracycline compounds and tetracycline derivatives |
| JP2005501058A (ja) * | 2001-07-31 | 2005-01-13 | ザ ガバメント オブ ザ ユナイテッドステイツ オブ アメリカ アズ リプレゼンテッド バイ ザ セクレタリー デパートメント オブ ヘルス アンド ヒューマン サービシーズ ザ ナショナル インステ | Glp−1、exendin−4、そのペプチド・アナログ及びその使用 |
| US20080015144A1 (en) | 2003-12-12 | 2008-01-17 | Alvert Einstein College Of Medicine Of Yeshiva Uni | Glp- (9-36) Methods and Compositions |
| US20090202497A1 (en) * | 2005-08-23 | 2009-08-13 | The General Hospital Corporation | Use of glp-1, glp-1 derivatives or glp-1 fragments for skin regeneration, stimulation of hair growth, or treatment of diabetes |
| AU2008297885A1 (en) * | 2007-09-11 | 2009-03-19 | Mondobiotech Laboratories Ag | Use of GLP-1 as a therapeutic agent |
| CA2713150C (en) * | 2008-02-07 | 2016-01-05 | Cornell University | Methods for preventing or treating insulin resistance |
| WO2010054326A2 (en) * | 2008-11-07 | 2010-05-14 | The General Hospital Corporation | C-terminal fragments of glucagon-like peptide-1 (glp-1) |
| DK2464371T3 (en) * | 2009-08-12 | 2016-06-27 | Univ Cornell | Methods for preventing or treating metabolic syndrome |
| EP2547352A4 (en) * | 2010-03-15 | 2013-10-09 | Stealth Peptides Int Inc | COMBINATION THERAPIES USING CYCLOSPORINE AND AROMATIC CATIONIC PEPTIDES |
| CN102614514B (zh) * | 2011-01-26 | 2014-12-10 | 王永祥 | Glp-1受体激动剂用于治疗疼痛 |
-
2013
- 2013-04-11 EP EP18188071.7A patent/EP3459598A1/en not_active Withdrawn
- 2013-04-11 CA CA2894182A patent/CA2894182A1/en not_active Abandoned
- 2013-04-11 CN CN201380072485.9A patent/CN104994912A/zh active Pending
- 2013-04-11 US US13/861,226 patent/US20130303436A1/en not_active Abandoned
- 2013-04-11 HK HK16103877.4A patent/HK1215934A1/zh unknown
- 2013-04-11 EP EP17184720.5A patent/EP3287172A1/en not_active Withdrawn
- 2013-04-11 WO PCT/US2013/036214 patent/WO2014088631A1/en not_active Ceased
- 2013-04-11 JP JP2015546449A patent/JP2016506391A/ja active Pending
- 2013-04-11 EP EP13861220.5A patent/EP2928562A4/en not_active Withdrawn
-
2015
- 2015-04-27 US US14/697,321 patent/US20160101158A1/en not_active Abandoned
-
2017
- 2017-07-28 JP JP2017146044A patent/JP2018021033A/ja active Pending
- 2017-12-21 US US15/850,092 patent/US20180344814A1/en not_active Abandoned
-
2018
- 2018-11-06 JP JP2018208926A patent/JP2019069942A/ja active Pending
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