JP2016506391A - ペプチド治療薬およびその使用方法 - Google Patents
ペプチド治療薬およびその使用方法 Download PDFInfo
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- JP2016506391A JP2016506391A JP2015546449A JP2015546449A JP2016506391A JP 2016506391 A JP2016506391 A JP 2016506391A JP 2015546449 A JP2015546449 A JP 2015546449A JP 2015546449 A JP2015546449 A JP 2015546449A JP 2016506391 A JP2016506391 A JP 2016506391A
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/22—Hormones
- A61K38/26—Glucagons
-
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- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
- A61K38/06—Tripeptides
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- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
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-
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-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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- A61P9/12—Antihypertensives
-
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- A61P9/14—Vasoprotectives; Antihaemorrhoidals; Drugs for varicose therapy; Capillary stabilisers
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/575—Hormones
- C07K14/605—Glucagons
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Organic Chemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Veterinary Medicine (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Neurology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Biomedical Technology (AREA)
- Diabetes (AREA)
- Neurosurgery (AREA)
- Gastroenterology & Hepatology (AREA)
- Endocrinology (AREA)
- Ophthalmology & Optometry (AREA)
- Cardiology (AREA)
- Epidemiology (AREA)
- Immunology (AREA)
- Biochemistry (AREA)
- Heart & Thoracic Surgery (AREA)
- Zoology (AREA)
- Molecular Biology (AREA)
- Genetics & Genomics (AREA)
- Biophysics (AREA)
- Toxicology (AREA)
- Hematology (AREA)
- Obesity (AREA)
- Urology & Nephrology (AREA)
- Pain & Pain Management (AREA)
- Physical Education & Sports Medicine (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Vascular Medicine (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201261734293P | 2012-12-06 | 2012-12-06 | |
| US61/734,293 | 2012-12-06 | ||
| PCT/US2013/036214 WO2014088631A1 (en) | 2012-12-06 | 2013-04-11 | Peptide therapeutics and methods for using same |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2017146044A Division JP2018021033A (ja) | 2012-12-06 | 2017-07-28 | ペプチド治療薬およびその使用方法 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2016506391A true JP2016506391A (ja) | 2016-03-03 |
| JP2016506391A5 JP2016506391A5 (enExample) | 2016-06-02 |
Family
ID=49549068
Family Applications (3)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2015546449A Pending JP2016506391A (ja) | 2012-12-06 | 2013-04-11 | ペプチド治療薬およびその使用方法 |
| JP2017146044A Pending JP2018021033A (ja) | 2012-12-06 | 2017-07-28 | ペプチド治療薬およびその使用方法 |
| JP2018208926A Pending JP2019069942A (ja) | 2012-12-06 | 2018-11-06 | ペプチド治療薬およびその使用方法 |
Family Applications After (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2017146044A Pending JP2018021033A (ja) | 2012-12-06 | 2017-07-28 | ペプチド治療薬およびその使用方法 |
| JP2018208926A Pending JP2019069942A (ja) | 2012-12-06 | 2018-11-06 | ペプチド治療薬およびその使用方法 |
Country Status (7)
| Country | Link |
|---|---|
| US (3) | US20130303436A1 (enExample) |
| EP (3) | EP2928562A4 (enExample) |
| JP (3) | JP2016506391A (enExample) |
| CN (1) | CN104994912A (enExample) |
| CA (1) | CA2894182A1 (enExample) |
| HK (1) | HK1215934A1 (enExample) |
| WO (1) | WO2014088631A1 (enExample) |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2019517586A (ja) * | 2016-06-03 | 2019-06-24 | ジェイティー ファーマスーティカルズ、インク. | カッパオピオイド受容体アゴニストの持続放出組成物 |
Families Citing this family (46)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| MX2015005102A (es) * | 2012-10-22 | 2016-02-09 | Stealth Peptides Int Inc | Metodos para la reduccion de los riesgos asociados con el insuficiencia cardiaca y factores asociado con el mismo. |
| US10772554B2 (en) * | 2013-09-04 | 2020-09-15 | Joseph Michael Lawless Kelly | Methods and systems for the detection of disease |
| US9895410B2 (en) * | 2013-12-12 | 2018-02-20 | Cornell University | Methods for preventing and treating oral cancers |
| SG10201805039UA (en) * | 2013-12-13 | 2018-07-30 | Medimmune Ltd | Protease resistant peptides |
| EP3082838A4 (en) * | 2013-12-16 | 2017-07-26 | Cornell University | Methods and compositions for treating and preventing cognitive dysfunction |
| CN112457368A (zh) * | 2013-12-27 | 2021-03-09 | 康德生物医疗技术公司 | 药学相关的芳香族阳离子肽 |
| CA2942143A1 (en) * | 2014-03-03 | 2015-09-11 | Stealth Biotherapeutics Corp | Pharmaceutically relevant aromatic-cationic peptides and methods of generating the same |
| WO2015183970A1 (en) * | 2014-05-28 | 2015-12-03 | Stealth Peptides International, Inc. | Therapeutic compositions including flavonoid and uses thereof |
| US10576124B2 (en) * | 2014-05-28 | 2020-03-03 | Stealth Biotherapeutics Corp | Therapeutic compositions including frataxin, lactoferrin, and mitochondrial energy generating enzymes, and uses thereof |
| WO2015183985A2 (en) * | 2014-05-28 | 2015-12-03 | Stealth Peptides International, Inc. | Therapeutic compositions including naphthoquinones and uses thereof |
| US20170182117A1 (en) * | 2014-05-28 | 2017-06-29 | Stealth Biotherapeutics Corp | Therapeutic compositions including therapeutic small molecules and uses thereof |
| WO2015183963A2 (en) * | 2014-05-28 | 2015-12-03 | Stealth Peptides International, Inc. | Therapeutic compositions including redox-active parabenzoquinones and uses thereof |
| WO2015183984A2 (en) * | 2014-05-28 | 2015-12-03 | Stealth Peptides International, Inc. | Therapeutic compositions including tocopherol and uses thereof |
| US10627392B2 (en) | 2014-06-17 | 2020-04-21 | Stealth Biotherapeutics Corp | Methods of identifying and monitoring mitochondrial dysfunction using monocyte screening |
| EP3182989B1 (en) | 2014-08-21 | 2021-04-14 | Stealth Biotherapeutics Corp | Peptide d-arg-2',6'-dmt-lys-phe-nh2 for treating alport syndrome |
| ES2630106T3 (es) * | 2014-10-07 | 2017-08-18 | Cyprumed Gmbh | Formulaciones farmacéuticas para la administración oral de fármacos peptídicos o proteicos |
| RU2711913C2 (ru) | 2014-11-07 | 2020-01-24 | Дзе Джонс Хопкинс Юниверсити | Лечение пигментной дистрофии сетчатки n-ацетилцистеинамидом |
| US20170315135A1 (en) * | 2014-11-11 | 2017-11-02 | The Johns Hopkins University | Biomarkers useful in the treatment of subjects having retinits pigmentosa |
| US11268964B2 (en) * | 2014-11-11 | 2022-03-08 | The Johns Hopkins University | Biomarkers useful in the treatment of subjects having diseases of the eye |
| CA2978905A1 (en) | 2015-03-06 | 2016-09-15 | Stealth Biotherapeutics Corp | Processes for preparing pharmaceutically relevant peptides |
| WO2016190852A1 (en) * | 2015-05-26 | 2016-12-01 | Stealth Peptides International, Inc. | Therapeutic compositions including chromanyl compounds, variants and analogues thereof, and uses thereof |
| WO2016195663A1 (en) * | 2015-06-02 | 2016-12-08 | Stealth Peptides International, Inc. | Therapeutic compositions including bpm 31510, variants and analogues thereof, and uses thereof |
| TWI726889B (zh) * | 2015-06-10 | 2021-05-11 | 英商梅迪繆思有限公司 | 蛋白酶抗性之脂化肽 |
| PL3393496T3 (pl) | 2015-12-23 | 2024-04-22 | The Johns Hopkins University | Długo działający agonista glp-1r jako terapia stanów neurologicznych i neurodegeneracyjnych |
| AU2017249218B2 (en) | 2016-04-11 | 2020-08-27 | Arcuate Therapeutics, Inc. | Chiral peptides |
| CN105987839B (zh) * | 2016-06-03 | 2018-09-28 | 浙江世纪康大医疗科技股份有限公司 | 一种edta-柠檬酸抗原修复液 |
| CN105987840B (zh) * | 2016-06-03 | 2018-09-28 | 浙江世纪康大医疗科技股份有限公司 | 一种柠檬酸抗原修复液 |
| CN107042067B (zh) * | 2017-05-24 | 2019-11-08 | 天津大学 | 聚硅氧烷-金属有机框架材料杂化渗透蒸发复合膜及其制备与应用 |
| TWI714862B (zh) * | 2017-06-19 | 2021-01-01 | 大陸商深圳瑞健生命科學硏究院有限公司 | 一種調控glp-1/glp-1r的方法和藥物 |
| EP3443980A1 (en) * | 2017-08-15 | 2019-02-20 | Ciliocure Limited | Compound for the treatment of patients with leptin-resistant obesity, bardet-biedl syndrome and other ciliopathies |
| CN111386255B (zh) | 2017-09-20 | 2021-11-23 | 纳崔泰制药有限公司 | 用于制备n-乙酰基半胱氨酸酰胺及其衍生物的方法 |
| US11091433B2 (en) | 2017-09-20 | 2021-08-17 | Nacuity Pharmaceutials, Inc. | Method for preparation of N-acetyl cysteine amide and derivatives thereof |
| US11548851B2 (en) | 2017-09-20 | 2023-01-10 | Nacuity Pharmaceuticals, Inc. | Method for preparation of n-acetyl cysteine amide and derivatives thereof |
| US20190135741A1 (en) | 2017-11-09 | 2019-05-09 | Nacuity Pharmaceuticals, Inc. | Methods of Making Deuterium-Enriched N-acetylcysteine Amide (D-NACA) and (2R, 2R')-3,3'-Disulfanediyl BIS(2-Acetamidopropanamide) (DINACA) and Using D-NACA and DINACA to Treat Diseases Involving Oxidative Stress |
| WO2019201333A1 (zh) * | 2018-04-19 | 2019-10-24 | 杭州先为达生物科技有限公司 | Glp-1衍生物及其治疗用途 |
| US11766413B2 (en) | 2019-01-11 | 2023-09-26 | Nacuity Pharmaceuticals, Inc. | Treatment of age-related macular degeneration, glaucoma, and diabetic retinopathy with n-acetylcysteine amide (NACA) or (2R,2R′)-3,3′-disulfanediyl BIS(2-acetamidopropanamide)(DiNACA) |
| US12458608B2 (en) | 2019-01-11 | 2025-11-04 | Nacuity Pharmaceuticals, Inc. | N-Acetylcysteine Amide (NACA) and (2R,2R′)-3,3′ disulfanediyl BIS(2-acetamidopropanamide) (DINACA) for the prevention and treatment of radiation dermatitis and skin lightening, skin whitening and skin improvement |
| AU2020316449A1 (en) * | 2019-07-24 | 2022-02-10 | Stealth Biotherapeutics Inc. | The peptidomimetic compound (R)-2-amino-N-((S)-L-(((S)-5-amino-L-(3-benzyl-1,2,4-oxadiazol-5-yl)pentyl)amino)-3-(4-hydroxy-2,6-dimethylphenyl)-l-oxopropan-2-yl)-5-guanidinopentanamide in the treatment of neurodegenerative diseases |
| US12383547B2 (en) | 2020-07-01 | 2025-08-12 | Vanderbilt University | Methods of treatment for a kidney disease |
| KR102503914B1 (ko) * | 2020-09-01 | 2023-02-24 | 인제대학교 산학협력단 | 황반변성 세포모델의 제조방법 |
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| CN114949184A (zh) * | 2022-05-13 | 2022-08-30 | 华中科技大学同济医学院附属同济医院 | Glp-1代谢物在制备减轻急性肾损伤药物中的用途 |
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Also Published As
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| CN104994912A (zh) | 2015-10-21 |
| EP3287172A1 (en) | 2018-02-28 |
| JP2018021033A (ja) | 2018-02-08 |
| EP2928562A1 (en) | 2015-10-14 |
| CA2894182A1 (en) | 2014-06-12 |
| US20180344814A1 (en) | 2018-12-06 |
| WO2014088631A1 (en) | 2014-06-12 |
| EP2928562A4 (en) | 2016-06-22 |
| EP3459598A1 (en) | 2019-03-27 |
| HK1215934A1 (zh) | 2016-09-30 |
| US20160101158A1 (en) | 2016-04-14 |
| JP2019069942A (ja) | 2019-05-09 |
| US20130303436A1 (en) | 2013-11-14 |
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