JP2016505619A5 - - Google Patents
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- JP2016505619A5 JP2016505619A5 JP2015551762A JP2015551762A JP2016505619A5 JP 2016505619 A5 JP2016505619 A5 JP 2016505619A5 JP 2015551762 A JP2015551762 A JP 2015551762A JP 2015551762 A JP2015551762 A JP 2015551762A JP 2016505619 A5 JP2016505619 A5 JP 2016505619A5
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- JP
- Japan
- Prior art keywords
- optionally substituted
- alkyl
- group
- halogen
- compound according
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
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- OPTCHSMAUQAOEX-UHFFFAOYSA-N CCC(O1)=C(C)OC1=O Chemical compound CCC(O1)=C(C)OC1=O OPTCHSMAUQAOEX-UHFFFAOYSA-N 0.000 description 1
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201361749204P | 2013-01-04 | 2013-01-04 | |
| US61/749,204 | 2013-01-04 | ||
| US201361780855P | 2013-03-13 | 2013-03-13 | |
| US61/780,855 | 2013-03-13 | ||
| PCT/US2014/010107 WO2014107536A1 (en) | 2013-01-04 | 2014-01-02 | Boronic acid derivatives and therapeutic uses thereof |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2016505619A JP2016505619A (ja) | 2016-02-25 |
| JP2016505619A5 true JP2016505619A5 (enExample) | 2017-02-09 |
| JP6324409B2 JP6324409B2 (ja) | 2018-05-16 |
Family
ID=51061420
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2015551762A Expired - Fee Related JP6324409B2 (ja) | 2013-01-04 | 2014-01-02 | ボロン酸誘導体及びその治療的使用 |
Country Status (12)
| Country | Link |
|---|---|
| US (1) | US9132140B2 (enExample) |
| EP (1) | EP2941247A4 (enExample) |
| JP (1) | JP6324409B2 (enExample) |
| KR (1) | KR20150103270A (enExample) |
| CN (1) | CN104981239B (enExample) |
| AU (1) | AU2014204046B2 (enExample) |
| BR (1) | BR112015016002A2 (enExample) |
| CA (1) | CA2894892A1 (enExample) |
| EA (1) | EA201591004A1 (enExample) |
| MX (1) | MX2015008627A (enExample) |
| TW (1) | TW201431865A (enExample) |
| WO (1) | WO2014107536A1 (enExample) |
Families Citing this family (39)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| KR102205755B1 (ko) | 2010-08-10 | 2021-01-22 | 렘펙스 파머수티클스 인코퍼레이티드 | 고리형 보론산 에스터 유도체의 결정 형태 |
| PT2928898T (pt) | 2012-12-07 | 2021-07-05 | Venatorx Pharmaceuticals Inc | Inibidores de beta-lactamase |
| JP2016509594A (ja) * | 2013-01-04 | 2016-03-31 | レンペックス・ファーマシューティカルズ・インコーポレイテッド | ボロン酸誘導体及びその治療的使用 |
| JP6346904B2 (ja) | 2013-01-10 | 2018-06-20 | ベナトルクス ファーマシューティカルズ，インク． | ベータ−ラクタマーゼ阻害剤 |
| WO2014151958A1 (en) | 2013-03-14 | 2014-09-25 | VenatoRx Pharmaceuticals, Inc. | Beta-lactamase inhibitors |
| FI3604316T3 (fi) | 2014-05-05 | 2024-02-29 | Melinta Therapeutics Inc | Boronaattisuolojen synteesi |
| US9687497B1 (en) | 2014-05-05 | 2017-06-27 | Rempex Pharmaceuticals, Inc. | Salts and polymorphs of cyclic boronic acid ester derivatives and therapeutic uses thereof |
| AU2015264418A1 (en) * | 2014-05-19 | 2016-11-10 | Rempex Pharmaceuticals, Inc. | Boronic acid derivatives and therapeutic uses thereof |
| US9511142B2 (en) | 2014-06-11 | 2016-12-06 | VenatoRx Pharmaceuticals, Inc. | Beta-lactamase inhibitors |
| RU2686740C2 (ru) | 2014-06-11 | 2019-04-30 | Венаторкс Фармасьютикалс, Инк. | Ингибиторы бета-лактамазы |
| EA201692301A1 (ru) * | 2014-07-01 | 2017-06-30 | Ремпекс Фармасьютикалз, Инк. | Производные бороновой кислоты и их терапевтическое применение |
| WO2016081297A1 (en) | 2014-11-18 | 2016-05-26 | Rempex Pharmaceuticals, Inc. | Cyclic boronic acid ester derivatives and therapeutic uses thereof |
| CN107207537B (zh) | 2014-12-19 | 2019-05-31 | 莱姆派克斯制药公司 | 用于生产硼酸衍生物的设备和连续流方法 |
| US20180051041A1 (en) | 2015-03-17 | 2018-02-22 | Rempex Pharmaceuticals, Inc. | Boronic acid derivatives and therapeutic uses thereof |
| CN108472284A (zh) | 2015-09-11 | 2018-08-31 | 维纳拓尔斯制药公司 | β-内酰胺酶抑制剂 |
| CN105116076B (zh) * | 2015-09-28 | 2017-06-30 | 苏州二叶制药有限公司 | 一种头孢地嗪钠有关物质的检测方法 |
| WO2017100537A1 (en) | 2015-12-10 | 2017-06-15 | VenatoRx Pharmaceuticals, Inc. | Beta-lactamase inhibitors |
| UA124464C2 (uk) | 2016-06-30 | 2021-09-22 | Кьюпекс Біофарма, Інк. | Похідні боронової кислоти та їх терапевтичні застосування |
| WO2018027062A1 (en) | 2016-08-04 | 2018-02-08 | VenatoRx Pharmaceuticals, Inc. | Boron-containing compounds |
| ES3015371T3 (en) | 2017-03-06 | 2025-05-05 | Venatorx Pharmaceuticals Inc | Solid forms and combination compositions comprising a beta-lactamase inhibitor and uses thereof |
| JP7377718B2 (ja) | 2017-05-12 | 2023-11-10 | エナンタ ファーマシューティカルズ インコーポレイテッド | アポトーシスシグナル調節キナーゼ１阻害剤およびその使用方法 |
| EP3630783A4 (en) | 2017-05-26 | 2021-03-03 | Venatorx Pharmaceuticals, Inc. | PENICILLIN-BINDING PROTEIN INHIBITORS |
| WO2018218190A1 (en) | 2017-05-26 | 2018-11-29 | VenatoRx Pharmaceuticals, Inc. | Penicillin-binding protein inhibitors |
| TW201906616A (zh) * | 2017-07-06 | 2019-02-16 | 日商大日本住友製藥股份有限公司 | 醯胺衍生物 |
| WO2019009369A1 (ja) * | 2017-07-06 | 2019-01-10 | 大日本住友製薬株式会社 | イミン誘導体 |
| EP3694864B1 (en) * | 2017-10-11 | 2025-03-05 | Qpex Biopharma, Inc. | Boronic acid derivatives and synthesis thereof |
| CN109696429A (zh) * | 2018-01-30 | 2019-04-30 | 湖南师范大学 | AO-CoOOH纳米荧光探针及其制备方法和应用 |
| WO2019204419A1 (en) * | 2018-04-20 | 2019-10-24 | The Medicines Company (San Diego), Llc | Boronic acid derivatives and therapeutic uses thereof |
| JP7360132B2 (ja) | 2018-04-27 | 2023-10-12 | 住友ファーマ株式会社 | オキソ置換化合物 |
| KR102798464B1 (ko) * | 2018-05-02 | 2025-04-21 | 이난타 파마슈티칼스, 인코포레이티드 | 아폽토시스 신호 조절 키나제 1 억제제를 포함하는 테트라졸 및 이의 사용 방법 |
| WO2019226931A1 (en) | 2018-05-25 | 2019-11-28 | VenatoRx Pharmaceuticals, Inc. | Penicillin-binding protein inhibitors |
| US10968199B2 (en) | 2018-08-22 | 2021-04-06 | Enanta Pharmaceuticals, Inc. | Cycloalkyl-containing apoptosis signal-regulating kinase 1 inhibitors and methods of use thereof |
| US11345699B2 (en) | 2018-11-19 | 2022-05-31 | Enanta Pharmaceuticals, Inc. | Apoptosis signal-regulating kinase 1 inhibitors and methods of use thereof |
| WO2020112542A1 (en) | 2018-11-29 | 2020-06-04 | VenatoRx Pharmaceuticals, Inc. | Combination compositions comprising a beta-lactamase inhibitor and uses thereof |
| WO2020198214A1 (en) | 2019-03-25 | 2020-10-01 | Enanta Pharmaceuticals, Inc. | Apoptosis signal-regulating kinase 1 inhibitors and methods of use thereof |
| CN114929715A (zh) | 2019-10-25 | 2022-08-19 | 住友制药株式会社 | 新型取代稠环型化合物 |
| AU2021266715A1 (en) | 2020-05-05 | 2022-11-17 | Qpex Biopharma, Inc. | Boronic acid derivatives and synthesis, polymorphic forms, and therapeutic uses thereof |
| US20240209004A1 (en) * | 2021-04-13 | 2024-06-27 | Tuojie Biotech (Shanghai) Co., Ltd. | BORIC ACID DERIVATIVE ACTING AS Beta-LACTAMASE INHIBITOR |
| TW202529745A (zh) | 2023-11-21 | 2025-08-01 | 美商維納拓爾斯製藥公司 | 經口遞送之β-內醯胺酶抑制劑之檸檬酸鹽配位錯合物及其用途 |
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| US10561675B2 (en) | 2012-06-06 | 2020-02-18 | Rempex Pharmaceuticals, Inc. | Cyclic boronic acid ester derivatives and therapeutic uses thereof |
| PT2928898T (pt) | 2012-12-07 | 2021-07-05 | Venatorx Pharmaceuticals Inc | Inibidores de beta-lactamase |
| US9241947B2 (en) | 2013-01-04 | 2016-01-26 | Rempex Pharmaceuticals, Inc. | Boronic acid derivatives and therapeutic uses thereof |
| US9101638B2 (en) | 2013-01-04 | 2015-08-11 | Rempex Pharmaceuticals, Inc. | Boronic acid derivatives and therapeutic uses thereof |
| JP2016509594A (ja) | 2013-01-04 | 2016-03-31 | レンペックス・ファーマシューティカルズ・インコーポレイテッド | ボロン酸誘導体及びその治療的使用 |
| JP6346904B2 (ja) | 2013-01-10 | 2018-06-20 | ベナトルクス ファーマシューティカルズ，インク． | ベータ−ラクタマーゼ阻害剤 |
| WO2014151958A1 (en) | 2013-03-14 | 2014-09-25 | VenatoRx Pharmaceuticals, Inc. | Beta-lactamase inhibitors |
-
2014
- 2014-01-02 JP JP2015551762A patent/JP6324409B2/ja not_active Expired - Fee Related
- 2014-01-02 EA EA201591004A patent/EA201591004A1/ru unknown
- 2014-01-02 BR BR112015016002A patent/BR112015016002A2/pt not_active IP Right Cessation
- 2014-01-02 CN CN201480003994.0A patent/CN104981239B/zh active Active
- 2014-01-02 MX MX2015008627A patent/MX2015008627A/es unknown
- 2014-01-02 EP EP14735389.0A patent/EP2941247A4/en not_active Withdrawn
- 2014-01-02 WO PCT/US2014/010107 patent/WO2014107536A1/en not_active Ceased
- 2014-01-02 US US14/146,643 patent/US9132140B2/en active Active
- 2014-01-02 KR KR1020157021054A patent/KR20150103270A/ko not_active Withdrawn
- 2014-01-02 CA CA2894892A patent/CA2894892A1/en not_active Abandoned
- 2014-01-02 AU AU2014204046A patent/AU2014204046B2/en not_active Ceased
- 2014-01-03 TW TW103100230A patent/TW201431865A/zh unknown
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