|
SE430062B
(sv)
|
1977-03-04 |
1983-10-17 |
Pharmacia Fine Chemicals Ab |
Kopplings- eller tioleringsreagens
|
|
US4137230A
(en)
|
1977-11-14 |
1979-01-30 |
Takeda Chemical Industries, Ltd. |
Method for the production of maytansinoids
|
|
US4307016A
(en)
|
1978-03-24 |
1981-12-22 |
Takeda Chemical Industries, Ltd. |
Demethyl maytansinoids
|
|
US4256746A
(en)
|
1978-11-14 |
1981-03-17 |
Takeda Chemical Industries |
Dechloromaytansinoids, their pharmaceutical compositions and method of use
|
|
JPS55102583A
(en)
|
1979-01-31 |
1980-08-05 |
Takeda Chem Ind Ltd |
20-acyloxy-20-demethylmaytansinoid compound
|
|
JPS55162791A
(en)
|
1979-06-05 |
1980-12-18 |
Takeda Chem Ind Ltd |
Antibiotic c-15003pnd and its preparation
|
|
JPS5645483A
(en)
|
1979-09-19 |
1981-04-25 |
Takeda Chem Ind Ltd |
C-15003phm and its preparation
|
|
JPS5645485A
(en)
|
1979-09-21 |
1981-04-25 |
Takeda Chem Ind Ltd |
Production of c-15003pnd
|
|
EP0028683A1
(en)
|
1979-09-21 |
1981-05-20 |
Takeda Chemical Industries, Ltd. |
Antibiotic C-15003 PHO and production thereof
|
|
WO1982001188A1
(en)
|
1980-10-08 |
1982-04-15 |
Takeda Chemical Industries Ltd |
4,5-deoxymaytansinoide compounds and process for preparing same
|
|
US4450254A
(en)
|
1980-11-03 |
1984-05-22 |
Standard Oil Company |
Impact improvement of high nitrile resins
|
|
US4313946A
(en)
|
1981-01-27 |
1982-02-02 |
The United States Of America As Represented By The Secretary Of Agriculture |
Chemotherapeutically active maytansinoids from Trewia nudiflora
|
|
US4315929A
(en)
|
1981-01-27 |
1982-02-16 |
The United States Of America As Represented By The Secretary Of Agriculture |
Method of controlling the European corn borer with trewiasine
|
|
US4563304A
(en)
|
1981-02-27 |
1986-01-07 |
Pharmacia Fine Chemicals Ab |
Pyridine compounds modifying proteins, polypeptides or polysaccharides
|
|
JPS57192389A
(en)
|
1981-05-20 |
1982-11-26 |
Takeda Chem Ind Ltd |
Novel maytansinoid
|
|
US4664911A
(en)
|
1983-06-21 |
1987-05-12 |
Board Of Regents, University Of Texas System |
Immunotoxin conjugates employing toxin B chain moieties
|
|
EP0192009B1
(fr)
|
1985-01-22 |
1991-09-04 |
Saint-Gobain Vitrage International |
Procédé de prèparation d'un poudre à base de formiate d'indium pour la formation d'une couche mince sur un substrat, notamment en verre.
|
|
GB8600582D0
(en)
|
1986-01-10 |
1986-02-19 |
Ca Minister Nat Defence |
Purifying biological materials
|
|
GB8607679D0
(en)
|
1986-03-27 |
1986-04-30 |
Winter G P |
Recombinant dna product
|
|
US5225539A
(en)
|
1986-03-27 |
1993-07-06 |
Medical Research Council |
Recombinant altered antibodies and methods of making altered antibodies
|
|
US4859449A
(en)
|
1987-09-14 |
1989-08-22 |
Center For Molecular Medicine And Immunology |
Modified antibodies for enhanced hepatocyte clearance
|
|
US5241078A
(en)
|
1988-06-14 |
1993-08-31 |
Cetus Oncology |
Coupling agents and sterically hindered disulfide linked conjugates prepared therefrom
|
|
US5024834A
(en)
|
1988-07-12 |
1991-06-18 |
Cetus Corporation |
Thioether linked immunotoxin conjugates
|
|
CA2006408A1
(en)
|
1988-12-27 |
1990-06-27 |
Susumu Iwasa |
Bispecific monoclonal antibody, its production and use
|
|
US5530101A
(en)
|
1988-12-28 |
1996-06-25 |
Protein Design Labs, Inc. |
Humanized immunoglobulins
|
|
US5714149A
(en)
|
1989-02-10 |
1998-02-03 |
Celltech Therapeutics Limited |
Crosslinked antibodies and processes for their preparation
|
|
CA2026147C
(en)
|
1989-10-25 |
2006-02-07 |
Ravi J. Chari |
Cytotoxic agents comprising maytansinoids and their therapeutic use
|
|
US5208020A
(en)
|
1989-10-25 |
1993-05-04 |
Immunogen Inc. |
Cytotoxic agents comprising maytansinoids and their therapeutic use
|
|
US6316003B1
(en)
|
1989-12-21 |
2001-11-13 |
Whitehead Institute For Biomedical Research |
Tat-derived transport polypeptides
|
|
US5137877B1
(en)
|
1990-05-14 |
1996-01-30 |
Bristol Myers Squibb Co |
Bifunctional linking compounds conjugates and methods for their production
|
|
GB9015198D0
(en)
|
1990-07-10 |
1990-08-29 |
Brien Caroline J O |
Binding substance
|
|
KR100272077B1
(ko)
|
1990-08-29 |
2000-11-15 |
젠팜인터내셔날,인코포레이티드 |
이종 항체를 생산할 수 있는 전이유전자를 가진 인간이외의 동물
|
|
US5545806A
(en)
|
1990-08-29 |
1996-08-13 |
Genpharm International, Inc. |
Ransgenic non-human animals for producing heterologous antibodies
|
|
CA2048078A1
(en)
|
1990-11-15 |
1992-05-16 |
Wolfgang A. Wrasidlo |
Chemical modification of antibodies for creation of immunoconjugates
|
|
US5252714A
(en)
|
1990-11-28 |
1993-10-12 |
The University Of Alabama In Huntsville |
Preparation and use of polyethylene glycol propionaldehyde
|
|
SE9102074D0
(sv)
|
1991-07-03 |
1991-07-03 |
Kabi Pharmacia Ab |
Tomour antigen specific antibody
|
|
SE470006B
(sv)
|
1991-09-26 |
1993-10-25 |
Corline Systems Ab |
Nytt konjugat, dess framställning och användning samt substrat preparerat med konjugatet
|
|
ATE408012T1
(de)
|
1991-12-02 |
2008-09-15 |
Medical Res Council |
Herstellung von autoantikörpern auf phagenoberflächen ausgehend von antikörpersegmentbibliotheken
|
|
ES2149768T3
(es)
|
1992-03-25 |
2000-11-16 |
Immunogen Inc |
Conjugados de agentes enlazantes de celulas derivados de cc-1065.
|
|
US5639641A
(en)
|
1992-09-09 |
1997-06-17 |
Immunogen Inc. |
Resurfacing of rodent antibodies
|
|
US5556623A
(en)
|
1993-03-30 |
1996-09-17 |
Eli Lilly And Company |
Antibody-drug conjugates
|
|
IL111748A0
(en)
|
1993-12-03 |
1995-01-24 |
Zeneca Ltd |
Proteins
|
|
US5919758A
(en)
|
1994-03-22 |
1999-07-06 |
Beth Israel Deaconess Medical Center |
Modified polypeptides with altered biological activity
|
|
US5747446A
(en)
|
1994-03-22 |
1998-05-05 |
Beth Israel Deaconess Medical Center |
Modified polypeptides with increased biological activity
|
|
US5580853A
(en)
|
1994-03-22 |
1996-12-03 |
New England Deaconess Hospital |
Modified polypeptides with increased biological activity
|
|
US5612474A
(en)
|
1994-06-30 |
1997-03-18 |
Eli Lilly And Company |
Acid labile immunoconjugate intermediates
|
|
WO1996039183A1
(en)
|
1995-05-31 |
1996-12-12 |
Fred Hutchinson Cancer Research Center |
Compositions and methods for targeted delivery of effector molecules
|
|
US6265150B1
(en)
|
1995-06-07 |
2001-07-24 |
Becton Dickinson & Company |
Phage antibodies
|
|
US5714352A
(en)
|
1996-03-20 |
1998-02-03 |
Xenotech Incorporated |
Directed switch-mediated DNA recombination
|
|
US5958872A
(en)
|
1996-04-01 |
1999-09-28 |
Apoptosis Technology, Inc. |
Active survival domains of IGF-IR and methods of use
|
|
WO1998026747A2
(en)
|
1996-12-17 |
1998-06-25 |
Terman David S |
Superantigen based methods and compositions for treatment of diseases
|
|
US6462070B1
(en)
|
1997-03-06 |
2002-10-08 |
The General Hospital Corporation |
Photosensitizer conjugates for pathogen targeting
|
|
US6371975B2
(en)
|
1998-11-06 |
2002-04-16 |
Neomend, Inc. |
Compositions, systems, and methods for creating in situ, chemically cross-linked, mechanical barriers
|
|
WO1998056906A1
(en)
|
1997-06-11 |
1998-12-17 |
Thoegersen Hans Christian |
Trimerising module
|
|
US6171586B1
(en)
|
1997-06-13 |
2001-01-09 |
Genentech, Inc. |
Antibody formulation
|
|
US5958677A
(en)
*
|
1997-07-28 |
1999-09-28 |
The New York Blood Center, Inc. |
Method for purifying viral nucleic acids
|
|
WO1999006587A2
(en)
|
1997-08-01 |
1999-02-11 |
Morphosys Ag |
Novel method and phage for the identification of nucleic acid sequences encoding members of a multimeric (poly)peptide complex
|
|
US5965714A
(en)
|
1997-10-02 |
1999-10-12 |
Connaught Laboratories, Inc. |
Method for the covalent attachment of polysaccharides to protein molecules
|
|
BR9815388A
(pt)
|
1997-10-03 |
2001-08-21 |
Galenica Pharmaceuticals Inc |
Polissacarìdeos formadores de iminas, sua preparação e seu uso como adjuvantes e imunoestimulantes
|
|
US6121236A
(en)
|
1998-03-24 |
2000-09-19 |
The Children's Medical Center Corporation |
Multivalent ligands which modulate angiogenesis
|
|
AU760669B2
(en)
|
1998-04-28 |
2003-05-22 |
Galenica Pharmaceuticals, Inc. |
Polysaccharide-antigen conjugates
|
|
US5981564A
(en)
|
1998-07-01 |
1999-11-09 |
Universite Laval |
Water-soluble derivatives of paclitaxel, method for producing same and uses thereof
|
|
CA2331789C
(en)
|
1998-07-13 |
2013-09-10 |
Board Of Regents, The University Of Texas System |
Cancer treatment methods using therapeutic conjugates that bind to aminophospholipids
|
|
US6780327B1
(en)
|
1999-02-25 |
2004-08-24 |
Pall Corporation |
Positively charged membrane
|
|
TW593241B
(en)
|
1999-04-20 |
2004-06-21 |
Hoffmann La Roche |
Carbamic acid derivatives
|
|
AUPQ014799A0
(en)
|
1999-05-04 |
1999-05-27 |
Access Pharmaceuticals Australia Pty Limited |
Amplification of folate-mediated targeting to tumor cells using polymers
|
|
EP1229934B1
(en)
|
1999-10-01 |
2014-03-05 |
Immunogen, Inc. |
Compositions and methods for treating cancer using immunoconjugates and chemotherapeutic agents
|
|
CA2388063C
(en)
|
1999-11-24 |
2010-06-08 |
Immunogen, Inc. |
Cytotoxic agents comprising taxanes and their therapeutic use
|
|
CA2395660A1
(en)
|
1999-12-29 |
2001-07-12 |
Immunogen, Inc. |
Cytotoxic agents comprising modified doxorubicins and daunorubicins and their therapeutic use
|
|
JP2004511425A
(ja)
|
2000-02-08 |
2004-04-15 |
ザ ペン ステート リサーチ ファウンデーション |
免疫療法に使用されるインターロイキン13受容体サブユニットアルファー2
|
|
US7097840B2
(en)
|
2000-03-16 |
2006-08-29 |
Genentech, Inc. |
Methods of treatment using anti-ErbB antibody-maytansinoid conjugates
|
|
US6632979B2
(en)
|
2000-03-16 |
2003-10-14 |
Genentech, Inc. |
Rodent HER2 tumor model
|
|
US6596503B1
(en)
|
2000-08-18 |
2003-07-22 |
East Carolina University |
Monoclonal antibody DS6, tumor-associated antigen CA6, and methods of use thereof
|
|
US6333410B1
(en)
|
2000-08-18 |
2001-12-25 |
Immunogen, Inc. |
Process for the preparation and purification of thiol-containing maytansinoids
|
|
US20060062786A1
(en)
|
2000-11-08 |
2006-03-23 |
Human Genome Sciences, Inc. |
Antibodies that immunospecifically bind to TRAIL receptors
|
|
AR032028A1
(es)
|
2001-01-05 |
2003-10-22 |
Pfizer |
Anticuerpos contra el receptor del factor de crecimiento similar a insulina
|
|
NZ545176A
(en)
|
2001-01-29 |
2008-05-30 |
Biogen Idec Inc |
Modified antibodies reactive with CD20 and methods of use
|
|
CA2436408A1
(en)
|
2001-02-07 |
2002-12-12 |
Beth Israel Deaconess Medical Center |
Modified psma ligands and uses related thereto
|
|
EP1610751A4
(en)
|
2001-04-26 |
2006-05-24 |
Univ Texas |
THERAPEUTIC AGENT / LIGAND CONJUGATE COMPOSITIONS, ITS SYNTHESIS PROCESSES AND ITS APPLICATION
|
|
CA2446806A1
(en)
|
2001-05-11 |
2002-11-21 |
Board Of Regents, The University Of Texas System |
Anti-cd26 monoclonal antibodies as therapy for diseases associated with cells expressing cd26
|
|
EP1258255A1
(en)
|
2001-05-18 |
2002-11-20 |
Boehringer Ingelheim International GmbH |
Conjugates of an antibody to CD44 and a maytansinoid
|
|
US6441163B1
(en)
|
2001-05-31 |
2002-08-27 |
Immunogen, Inc. |
Methods for preparation of cytotoxic conjugates of maytansinoids and cell binding agents
|
|
JP4619651B2
(ja)
|
2001-06-01 |
2011-01-26 |
コーネル・リサーチ・ファンデーション・インコーポレイテッド |
前立腺特異的膜抗原に対する修飾抗体およびその使用
|
|
US6576802B2
(en)
|
2001-06-04 |
2003-06-10 |
Shell Oil Company |
One-step production of 1, 3-propanediol from ethylene oxide and syngas with a catalyst with a phospholanoalkane ligand
|
|
WO2003053462A2
(en)
|
2001-12-11 |
2003-07-03 |
Merck & Co., Inc. |
Staphylococcus aureus exopolysaccharide and process
|
|
US6716821B2
(en)
|
2001-12-21 |
2004-04-06 |
Immunogen Inc. |
Cytotoxic agents bearing a reactive polyethylene glycol moiety, cytotoxic conjugates comprising polyethylene glycol linking groups, and methods of making and using the same
|
|
US20050031627A1
(en)
|
2002-01-03 |
2005-02-10 |
Mazzola Gregory J |
Methods for preparing immunoconjugates
|
|
US7591994B2
(en)
|
2002-12-13 |
2009-09-22 |
Immunomedics, Inc. |
Camptothecin-binding moiety conjugates
|
|
US8877901B2
(en)
|
2002-12-13 |
2014-11-04 |
Immunomedics, Inc. |
Camptothecin-binding moiety conjugates
|
|
US6756397B2
(en)
|
2002-04-05 |
2004-06-29 |
Immunogen, Inc. |
Prodrugs of CC-1065 analogs
|
|
US6534660B1
(en)
|
2002-04-05 |
2003-03-18 |
Immunogen, Inc. |
CC-1065 analog synthesis
|
|
JP4319979B2
(ja)
|
2002-04-26 |
2009-08-26 |
ジェネンテック・インコーポレーテッド |
タンパク質の非アフィニティ精製
|
|
TWI438010B
(zh)
|
2002-05-02 |
2014-05-21 |
Wyeth Corp |
卡奇黴素(calicheamicin)衍生物-載體共軛物
|
|
US20090068178A1
(en)
|
2002-05-08 |
2009-03-12 |
Genentech, Inc. |
Compositions and Methods for the Treatment of Tumor of Hematopoietic Origin
|
|
US6596757B1
(en)
|
2002-05-14 |
2003-07-22 |
Immunogen Inc. |
Cytotoxic agents comprising polyethylene glycol-containing taxanes and their therapeutic use
|
|
CN1671741A
(zh)
|
2002-06-21 |
2005-09-21 |
拜奥根Idec公司 |
浓缩抗体的缓冲剂制剂及其使用方法
|
|
US7390898B2
(en)
|
2002-08-02 |
2008-06-24 |
Immunogen Inc. |
Cytotoxic agents containing novel potent taxanes and their therapeutic use
|
|
JP2006500364A
(ja)
|
2002-08-16 |
2006-01-05 |
イムノージェン インコーポレーテッド |
高い反応性と溶解度を有する架橋剤および小分子薬物の標的化送達用コンジュゲートの調製におけるそれらの使用
|
|
US7538092B2
(en)
|
2002-10-08 |
2009-05-26 |
Fresenius Kabi Deutschland Gmbh |
Pharmaceutically active oligosaccharide conjugates
|
|
CN106337046B
(zh)
|
2002-10-30 |
2021-03-23 |
纽韦卢森公司 |
合成双功能复合物的方法
|
|
WO2004043344A2
(en)
|
2002-11-07 |
2004-05-27 |
Immunogen, Inc. |
Anti-cd33 antibodies and method for treatment of acute myeloid leukemia using the same
|
|
US8088387B2
(en)
|
2003-10-10 |
2012-01-03 |
Immunogen Inc. |
Method of targeting specific cell populations using cell-binding agent maytansinoid conjugates linked via a non-cleavable linker, said conjugates, and methods of making said conjugates
|
|
EP2281577B1
(en)
|
2003-05-14 |
2016-11-16 |
ImmunoGen, Inc. |
Drug conjugate composition
|
|
PL1651162T3
(pl)
|
2003-05-20 |
2016-04-29 |
Immunogen Inc |
Maitansynoidy w leczeniu nowotworów
|
|
US7276497B2
(en)
|
2003-05-20 |
2007-10-02 |
Immunogen Inc. |
Cytotoxic agents comprising new maytansinoids
|
|
KR101531400B1
(ko)
|
2003-06-27 |
2015-06-26 |
암젠 프레몬트 인코포레이티드 |
상피 성장 인자 수용체의 결실 돌연변이체 지향 항체 및 그용도
|
|
WO2005002597A1
(en)
|
2003-07-02 |
2005-01-13 |
Polycord, Inc. |
Method for delivering polymerized therapeutic agent compositions and compositions thereof
|
|
EP1682179A4
(en)
|
2003-11-05 |
2008-09-03 |
Palingen Inc |
IMPROVED B-CELL CYTOTOXICITY OF CDIM BINDING ANTIBODY
|
|
US20050175619A1
(en)
|
2004-02-05 |
2005-08-11 |
Robert Duffy |
Methods of producing antibody conjugates
|
|
US20110064754A1
(en)
|
2005-03-03 |
2011-03-17 |
Center For Molecular Medicine And Immunology |
Immunoconjugates Comprising Poxvirus-Derived Peptides and Antibodies Against Antigen-Presenting Cells for Subunit-Based Poxvirus Vaccines
|
|
WO2005094882A1
(en)
|
2004-03-03 |
2005-10-13 |
Millennium Pharmaceuticals, Inc. |
Modified antibodies to prostate-specific membrane antigen and uses thereof
|
|
US8470315B2
(en)
|
2004-04-13 |
2013-06-25 |
Quintessence Biosciences, Inc. |
Non-natural ribonuclease conjugates as cytotoxic agents
|
|
US20060073528A1
(en)
|
2004-05-14 |
2006-04-06 |
Jean-Michel Lecerf |
Measurement methods
|
|
RU2402548C2
(ru)
|
2004-05-19 |
2010-10-27 |
Медарекс, Инк. |
Химические линкеры и их конъюгаты
|
|
MXPA06013413A
(es)
|
2004-05-19 |
2007-01-23 |
Medarex Inc |
Enlazadores quimicos y conjugados de los mismos.
|
|
MXPA06014065A
(es)
|
2004-06-01 |
2007-01-31 |
Genentech Inc |
Conjugados de droga-anticuerpo y metodos.
|
|
US20060045877A1
(en)
|
2004-08-30 |
2006-03-02 |
Goldmakher Viktor S |
Immunoconjugates targeting syndecan-1 expressing cells and use thereof
|
|
TW200630106A
(en)
|
2004-10-08 |
2006-09-01 |
Wyeth Corp |
Immunotherapy of autoimmune disorders
|
|
AU2005316844A1
(en)
|
2004-11-29 |
2006-06-22 |
Seattle Genetics, Inc. |
Engineered antibodies and immunoconjugates
|
|
WO2006062779A2
(en)
|
2004-12-09 |
2006-06-15 |
Centocor, Inc. |
Anti-integrin immunoconjugates, methods and uses
|
|
US7408030B2
(en)
|
2005-01-13 |
2008-08-05 |
North Carolina State University |
Purification of immunoglobulins using affinity chromatography and peptide ligands
|
|
US20110166319A1
(en)
|
2005-02-11 |
2011-07-07 |
Immunogen, Inc. |
Process for preparing purified drug conjugates
|
|
US20060182750A1
(en)
*
|
2005-02-11 |
2006-08-17 |
Immunogen, Inc. |
Process for preparing stable drug conjugates
|
|
EP1869084A2
(en)
|
2005-03-04 |
2007-12-26 |
Biogen Idec MA Inc. |
Methods of humanizing immunoglobulin variable regions through rational modification of complementarity determining residues
|
|
BRPI0608175A2
(pt)
|
2005-04-15 |
2009-11-10 |
Immunogen Inc |
método de eliminação de população de células heterogêneas ou mistas em tumores, assim como compostos maitansinóides
|
|
GB2427360A
(en)
|
2005-06-22 |
2006-12-27 |
Complex Biosystems Gmbh |
Aliphatic prodrug linker
|
|
WO2007009229A1
(en)
|
2005-07-15 |
2007-01-25 |
Angiochem Inc. |
Use of aprotinin polypeptides as carriers in pharmaceutical conjugates
|
|
WO2007019232A2
(en)
|
2005-08-03 |
2007-02-15 |
Immunogen, Inc. |
Immunoconjugate formulations
|
|
CA2893252C
(en)
|
2005-08-24 |
2018-05-29 |
Immunogen, Inc. |
Process for preparing antibody maytansinoid conjugates
|
|
CA2625426A1
(en)
|
2005-09-22 |
2007-03-29 |
Hadasit Medical Research Services & Development Limited |
Dextran and arabinogalactan conjugates of therapeutically active compounds
|
|
JP5290756B2
(ja)
|
2005-09-26 |
2013-09-18 |
メダレックス インコーポレイテッド |
抗体−薬剤コンジュゲート及びその使用
|
|
US7928113B2
(en)
|
2005-11-14 |
2011-04-19 |
University Of Southern California |
Integrin-binding small molecules
|
|
US7964415B2
(en)
|
2006-04-26 |
2011-06-21 |
Cardiogenics Inc. |
Stable water-soluble polyethylenimine conjugates and methods of use thereof
|
|
HRP20140172T1
(hr)
|
2006-05-30 |
2014-03-28 |
Genentech, Inc. |
Protutijela i imunokonjugati kao i njihove uporabe
|
|
CN101622276B
(zh)
*
|
2006-07-18 |
2015-04-22 |
赛诺菲-安万特 |
用于治疗癌症的抗epha2的拮抗抗体
|
|
US20080213349A1
(en)
|
2006-09-11 |
2008-09-04 |
Deepak Ramesh Thakker |
Liposome Complexes Containing Pharmaceutical Agents and Methods
|
|
JP2010505874A
(ja)
*
|
2006-10-03 |
2010-02-25 |
ノヴォ ノルディスク アー/エス |
ポリペプチドコンジュゲートの精製方法
|
|
EP1914242A1
(en)
|
2006-10-19 |
2008-04-23 |
Sanofi-Aventis |
Novel anti-CD38 antibodies for the treatment of cancer
|
|
DK2019104T3
(da)
*
|
2007-07-19 |
2013-12-16 |
Sanofi Sa |
Cytotoksiske midler, der omfatter nye tomaymycinderivater, og terapeutisk anvendelse deraf
|
|
BRPI0911442A2
(pt)
|
2008-04-30 |
2019-03-12 |
Immunogen, Inc. |
conjugados potentes e ligantes hidrofílicos
|
|
CN102076717B
(zh)
*
|
2008-04-30 |
2016-02-03 |
伊缪诺金公司 |
交联剂和它们的用途
|
|
GB0811743D0
(en)
|
2008-06-26 |
2008-07-30 |
Hemosol Biopharma Inc |
Composition
|
|
US20110223257A1
(en)
|
2008-11-17 |
2011-09-15 |
Enzon Pharmaceuticals, Inc. |
Releasable fusogenic lipids for nucleic acids delivery systems
|
|
US8426402B2
(en)
|
2009-02-05 |
2013-04-23 |
Immunogen, Inc. |
Benzodiazepine derivatives
|
|
UY32560A
(es)
|
2009-04-29 |
2010-11-30 |
Bayer Schering Pharma Ag |
Inmunoconjugados de antimesotelina y usos de los mismos
|
|
ME03479B
(me)
|
2009-06-03 |
2020-01-20 |
Immunogen Inc |
Metodi konjugacije
|
|
FR2947269B1
(fr)
|
2009-06-29 |
2013-01-18 |
Sanofi Aventis |
Nouveaux composes anticancereux
|
|
UY32913A
(es)
|
2009-10-02 |
2011-04-29 |
Sanofi Aventis |
Nuevos maitansinoides y el uso de dichos maitansinoides para preparar conjugados con un anticuero
|
|
TW201116297A
(en)
*
|
2009-10-02 |
2011-05-16 |
Sanofi Aventis |
Antibodies that specifically bind to the EphA2 receptor
|
|
SG10201501342UA
(en)
|
2010-02-24 |
2015-04-29 |
Immunogen Inc |
Folate receptor 1 antibodies and immunoconjugates and uses thereof
|
|
SG10201501803YA
(en)
|
2010-03-12 |
2015-05-28 |
Immunogen Inc |
Cd37-binding molecules and immunoconjugates thereof
|
|
WO2012019024A2
(en)
|
2010-08-04 |
2012-02-09 |
Immunogen, Inc. |
Her3-binding molecules and immunoconjugates thereof
|
|
AU2011320314B2
(en)
|
2010-10-29 |
2015-08-06 |
Immunogen, Inc. |
Novel EGFR-binding molecules and immunoconjugates thereof
|
|
EA201390575A1
(ru)
|
2010-10-29 |
2014-01-30 |
Иммьюноджен, Инк. |
Неантагонистические egfr-связывающие молекулы и их иммуноконъюгаты
|
|
US20120149732A1
(en)
|
2010-12-14 |
2012-06-14 |
Alexander Chucholowski |
Multifunctional linkers and methods for the use thereof
|
|
IL279304B
(en)
|
2011-02-15 |
2022-07-01 |
Immunogen Inc |
Method for producing an indolinobenzodiazepine
|
|
ME03353B
(me)
|
2011-03-29 |
2019-10-20 |
Immunogen Inc |
Priprema konjugata antitela i majtanzinoida jednostepenim postupkom
|
|
WO2012135522A2
(en)
|
2011-03-29 |
2012-10-04 |
Immunogen, Inc. |
Process for manufacturing conjugates of improved homogeneity
|
|
CA2831562A1
(en)
|
2011-03-29 |
2012-10-04 |
Immunogen, Inc. |
Process for manufacturing conjugates of improved homogeneity
|
|
SI2694106T1
(en)
|
2011-04-01 |
2018-04-30 |
Immunogen, Inc. |
Methods for increasing the effectiveness of treatment with FOLR1 receptor cancer
|
|
US20130071482A1
(en)
|
2011-09-20 |
2013-03-21 |
The University Of Kentucky Research Foundation |
Block copolymer cross-linked nanoassemblies as modular delivery vehicles
|
|
BR112014014464A2
(pt)
|
2011-12-13 |
2017-06-13 |
Immunogen Inc |
uso de n-hidroxisuccinimida para melhorar a estabilidade do conjugado
|
|
WO2014055842A1
(en)
|
2012-10-04 |
2014-04-10 |
Immunogen, Inc. |
Process for preparing stable antibody maytansinoid conjugates
|
|
AU2013326881B2
(en)
|
2012-10-04 |
2018-08-02 |
Immunogen, Inc. |
Use of a PVDF membrane to purify cell-binding agent cytotoxic agent conjugates
|
|
AU2013326897A1
(en)
|
2012-10-04 |
2015-05-07 |
Immunogen, Inc. |
Use of an ion exchange membrane to remove impurities from cell-binding agent cytotoxic agent conjugates
|
|
US10253099B2
(en)
|
2012-12-05 |
2019-04-09 |
Ruprecht-Karls-Universität Heidelberg |
Conjugates of proteins and multivalent cell-penetrating peptides and their uses
|