JP2016500703A5 - - Google Patents
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- Publication number
- JP2016500703A5 JP2016500703A5 JP2015540762A JP2015540762A JP2016500703A5 JP 2016500703 A5 JP2016500703 A5 JP 2016500703A5 JP 2015540762 A JP2015540762 A JP 2015540762A JP 2015540762 A JP2015540762 A JP 2015540762A JP 2016500703 A5 JP2016500703 A5 JP 2016500703A5
- Authority
- JP
- Japan
- Prior art keywords
- alkyl
- compound according
- pharmaceutically acceptable
- acceptable salt
- halo
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 125000000217 alkyl group Chemical group 0.000 claims 40
- 150000003839 salts Chemical class 0.000 claims 15
- 150000001875 compounds Chemical class 0.000 claims 14
- 125000001475 halogen functional group Chemical group 0.000 claims 11
- 125000000171 (C1-C6) haloalkyl group Chemical group 0.000 claims 8
- 125000000753 cycloalkyl group Chemical group 0.000 claims 8
- 125000000623 heterocyclic group Chemical group 0.000 claims 6
- 125000001072 heteroaryl group Chemical group 0.000 claims 4
- 125000000882 C2-C6 alkenyl group Chemical group 0.000 claims 2
- 125000003118 aryl group Chemical group 0.000 claims 2
- 239000008194 pharmaceutical composition Substances 0.000 claims 2
- 125000006570 (C5-C6) heteroaryl group Chemical group 0.000 claims 1
- 208000035473 Communicable disease Diseases 0.000 claims 1
- 125000004093 cyano group Chemical group *C#N 0.000 claims 1
- 201000010099 disease Diseases 0.000 claims 1
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 claims 1
- 125000001188 haloalkyl group Chemical group 0.000 claims 1
- 208000015181 infectious disease Diseases 0.000 claims 1
- 230000002265 prevention Effects 0.000 claims 1
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201261722154P | 2012-11-03 | 2012-11-03 | |
| US61/722,154 | 2012-11-03 | ||
| PCT/US2013/067670 WO2014070976A1 (en) | 2012-11-03 | 2013-10-31 | Inhibitors of cytomegalovirus |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2016500703A JP2016500703A (ja) | 2016-01-14 |
| JP2016500703A5 true JP2016500703A5 (enExample) | 2016-12-15 |
| JP6237779B2 JP6237779B2 (ja) | 2017-11-29 |
Family
ID=49620279
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2015540762A Active JP6237779B2 (ja) | 2012-11-03 | 2013-10-31 | サイトメガロウイルスの阻害薬 |
Country Status (4)
| Country | Link |
|---|---|
| US (1) | US9505775B2 (enExample) |
| EP (1) | EP2914588B1 (enExample) |
| JP (1) | JP6237779B2 (enExample) |
| WO (1) | WO2014070976A1 (enExample) |
Families Citing this family (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2020053654A1 (en) | 2018-09-12 | 2020-03-19 | Novartis Ag | Antiviral pyridopyrazinedione compounds |
| CA3155287A1 (en) | 2019-09-26 | 2021-04-01 | Novartis Ag | Antiviral pyrazolopyridinone compounds |
| US20230136702A1 (en) * | 2020-03-03 | 2023-05-04 | The Governors Of The University Of Alberta | Inhibitors of Human Herpesviruses |
| JP2025517423A (ja) * | 2022-05-20 | 2025-06-05 | ギリアード サイエンシーズ， インコーポレイテッド | 抗ウイルスインドリニル化合物及びその使用 |
| CN116675686B (zh) * | 2023-05-12 | 2025-08-29 | 河南省锐达医药科技有限公司 | 一种异吲哚啉基-哌啶甲酰胺类化合物、其制备方法及应用 |
Family Cites Families (13)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4423050A (en) | 1981-05-21 | 1983-12-27 | Syntex (U.S.A.) Inc. | 9-(1,3-Dihydroxy-2-propoxymethyl)guanine as antiviral agent |
| US4355032B2 (en) * | 1981-05-21 | 1990-10-30 | 9-(1,3-dihydroxy-2-propoxymethyl)guanine as antiviral agent | |
| US6342501B1 (en) * | 1994-02-25 | 2002-01-29 | The Regents Of The University Of Michigan | Pyrrolo[2,3-d] pyrimidines as antiviral agents |
| DK1064273T3 (da) * | 1998-03-19 | 2003-03-31 | Upjohn Co | 1,3,4-Thiadiazoler, som er nyttige til behandling af CMV-infektioner |
| US6248739B1 (en) * | 1999-01-08 | 2001-06-19 | Pharmacia & Upjohn Company | Quinolinecarboxamides as antiviral agents |
| EA200201002A1 (ru) * | 2000-03-21 | 2003-02-27 | Фармация Энд Апджон Компани | 4-оксо-1,4-дигидро-3-циннолинкарбоксамиды как противовирусные агенты |
| US20030130264A1 (en) | 2001-02-16 | 2003-07-10 | Tularik Inc. | Methods of using pyrimidine-based antiviral agents |
| WO2002070487A1 (en) | 2001-03-01 | 2002-09-12 | Pharmacia & Upjohn Company | Substituted quinolinecarboxamides as antiviral agents |
| AR038117A1 (es) * | 2002-01-14 | 2004-12-29 | Upjohn Co | Agentes antivirales derivados de la 4- oxo-4,7 -dihidrofuro [2,3-b]piridin-5-carboxamida |
| WO2004106345A2 (en) | 2002-09-04 | 2004-12-09 | Pharmacia & Upjohn Company | Heteroaryl-ethanolamine derivatives as antiviral agents |
| US7407744B2 (en) | 2003-07-25 | 2008-08-05 | The Regents Of The University Of California | Cytomegalovirus gene function and methods for developing antivirals, anti-CMV vaccines, and CMV-based vectors |
| WO2009011850A2 (en) * | 2007-07-16 | 2009-01-22 | Abbott Laboratories | Novel therapeutic compounds |
| TW201011009A (en) | 2008-09-15 | 2010-03-16 | Priaxon Ag | Novel pyrrolidin-2-ones |
-
2013
- 2013-10-31 US US14/440,085 patent/US9505775B2/en active Active
- 2013-10-31 JP JP2015540762A patent/JP6237779B2/ja active Active
- 2013-10-31 EP EP13792793.5A patent/EP2914588B1/en active Active
- 2013-10-31 WO PCT/US2013/067670 patent/WO2014070976A1/en not_active Ceased