JP2016006108A5 - - Google Patents
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- Publication number
- JP2016006108A5 JP2016006108A5 JP2015162398A JP2015162398A JP2016006108A5 JP 2016006108 A5 JP2016006108 A5 JP 2016006108A5 JP 2015162398 A JP2015162398 A JP 2015162398A JP 2015162398 A JP2015162398 A JP 2015162398A JP 2016006108 A5 JP2016006108 A5 JP 2016006108A5
- Authority
- JP
- Japan
- Prior art keywords
- dosage form
- oral pharmaceutical
- pharmaceutical dosage
- pharmaceutically acceptable
- acceptable salt
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- 239000002552 dosage form Substances 0.000 claims 36
- 150000003839 salts Chemical class 0.000 claims 20
- RMRJXGBAOAMLHD-IHFGGWKQSA-N buprenorphine Chemical compound C([C@]12[C@H]3OC=4C(O)=CC=C(C2=4)C[C@@H]2[C@]11CC[C@]3([C@H](C1)[C@](C)(O)C(C)(C)C)OC)CN2CC1CC1 RMRJXGBAOAMLHD-IHFGGWKQSA-N 0.000 claims 15
- 229960001736 buprenorphine Drugs 0.000 claims 15
- 239000001866 hydroxypropyl methyl cellulose Substances 0.000 claims 6
- 235000010979 hydroxypropyl methyl cellulose Nutrition 0.000 claims 6
- 229920003088 hydroxypropyl methyl cellulose Polymers 0.000 claims 6
- UFVKGYZPFZQRLF-UHFFFAOYSA-N hydroxypropyl methyl cellulose Chemical group OC1C(O)C(OC)OC(CO)C1OC1C(O)C(O)C(OC2C(C(O)C(OC3C(C(O)C(O)C(CO)O3)O)C(CO)O2)O)C(CO)O1 UFVKGYZPFZQRLF-UHFFFAOYSA-N 0.000 claims 6
- 229920002678 cellulose Polymers 0.000 claims 5
- 239000001913 cellulose Substances 0.000 claims 5
- 229920000642 polymer Polymers 0.000 claims 5
- 229920000663 Hydroxyethyl cellulose Polymers 0.000 claims 4
- 239000004354 Hydroxyethyl cellulose Substances 0.000 claims 4
- 229920001479 Hydroxyethyl methyl cellulose Polymers 0.000 claims 4
- 229920002153 Hydroxypropyl cellulose Polymers 0.000 claims 4
- 235000019447 hydroxyethyl cellulose Nutrition 0.000 claims 4
- 239000001863 hydroxypropyl cellulose Substances 0.000 claims 4
- 235000010977 hydroxypropyl cellulose Nutrition 0.000 claims 4
- 229920000609 methyl cellulose Polymers 0.000 claims 4
- 239000001923 methylcellulose Substances 0.000 claims 4
- UZHSEJADLWPNLE-GRGSLBFTSA-N naloxone Chemical compound O=C([C@@H]1O2)CC[C@@]3(O)[C@H]4CC5=CC=C(O)C2=C5[C@@]13CCN4CC=C UZHSEJADLWPNLE-GRGSLBFTSA-N 0.000 claims 4
- 229960004127 naloxone Drugs 0.000 claims 4
- 108090000623 proteins and genes Proteins 0.000 claims 4
- 102000004169 proteins and genes Human genes 0.000 claims 4
- 229920003171 Poly (ethylene oxide) Polymers 0.000 claims 3
- 150000004676 glycans Chemical class 0.000 claims 3
- 229920001282 polysaccharide Polymers 0.000 claims 3
- 239000005017 polysaccharide Substances 0.000 claims 3
- 229920002134 Carboxymethyl cellulose Polymers 0.000 claims 2
- 241000196324 Embryophyta Species 0.000 claims 2
- 229920000084 Gum arabic Polymers 0.000 claims 2
- 229920000881 Modified starch Polymers 0.000 claims 2
- 239000004372 Polyvinyl alcohol Substances 0.000 claims 2
- 241000978776 Senegalia senegal Species 0.000 claims 2
- 229920002472 Starch Polymers 0.000 claims 2
- 235000010489 acacia gum Nutrition 0.000 claims 2
- 239000000205 acacia gum Substances 0.000 claims 2
- 229920001577 copolymer Polymers 0.000 claims 2
- 229940079593 drug Drugs 0.000 claims 2
- 239000003814 drug Substances 0.000 claims 2
- FPYJFEHAWHCUMM-UHFFFAOYSA-N maleic anhydride Chemical compound O=C1OC(=O)C=C1 FPYJFEHAWHCUMM-UHFFFAOYSA-N 0.000 claims 2
- 239000011159 matrix material Substances 0.000 claims 2
- 244000005700 microbiome Species 0.000 claims 2
- 235000019426 modified starch Nutrition 0.000 claims 2
- 229920000058 polyacrylate Polymers 0.000 claims 2
- 229920002451 polyvinyl alcohol Polymers 0.000 claims 2
- 229920000036 polyvinylpyrrolidone Polymers 0.000 claims 2
- 239000001267 polyvinylpyrrolidone Substances 0.000 claims 2
- 235000013855 polyvinylpyrrolidone Nutrition 0.000 claims 2
- 235000018102 proteins Nutrition 0.000 claims 2
- 238000009256 replacement therapy Methods 0.000 claims 2
- 235000019698 starch Nutrition 0.000 claims 2
- 239000008107 starch Substances 0.000 claims 2
- 229920003169 water-soluble polymer Polymers 0.000 claims 2
- FHVDTGUDJYJELY-UHFFFAOYSA-N 6-{[2-carboxy-4,5-dihydroxy-6-(phosphanyloxy)oxan-3-yl]oxy}-4,5-dihydroxy-3-phosphanyloxane-2-carboxylic acid Chemical compound O1C(C(O)=O)C(P)C(O)C(O)C1OC1C(C(O)=O)OC(OP)C(O)C1O FHVDTGUDJYJELY-UHFFFAOYSA-N 0.000 claims 1
- NIXOWILDQLNWCW-UHFFFAOYSA-M Acrylate Chemical compound [O-]C(=O)C=C NIXOWILDQLNWCW-UHFFFAOYSA-M 0.000 claims 1
- 229920001353 Dextrin Polymers 0.000 claims 1
- 239000004375 Dextrin Substances 0.000 claims 1
- 108010010803 Gelatin Proteins 0.000 claims 1
- 239000004373 Pullulan Substances 0.000 claims 1
- 229920001218 Pullulan Polymers 0.000 claims 1
- QYKIQEUNHZKYBP-UHFFFAOYSA-N Vinyl ether Chemical compound C=COC=C QYKIQEUNHZKYBP-UHFFFAOYSA-N 0.000 claims 1
- 150000001252 acrylic acid derivatives Chemical class 0.000 claims 1
- 229940072056 alginate Drugs 0.000 claims 1
- 235000010443 alginic acid Nutrition 0.000 claims 1
- 229920000615 alginic acid Polymers 0.000 claims 1
- 235000019425 dextrin Nutrition 0.000 claims 1
- 229920000159 gelatin Polymers 0.000 claims 1
- 239000008273 gelatin Substances 0.000 claims 1
- 235000019322 gelatine Nutrition 0.000 claims 1
- 235000011852 gelatine desserts Nutrition 0.000 claims 1
- 125000002496 methyl group Chemical group [H]C([H])([H])* 0.000 claims 1
- XJRBAMWJDBPFIM-UHFFFAOYSA-N methyl vinyl ether Chemical compound COC=C XJRBAMWJDBPFIM-UHFFFAOYSA-N 0.000 claims 1
- 239000000203 mixture Substances 0.000 claims 1
- 239000003401 opiate antagonist Substances 0.000 claims 1
- 239000001814 pectin Substances 0.000 claims 1
- 235000010987 pectin Nutrition 0.000 claims 1
- 229920001277 pectin Polymers 0.000 claims 1
- 235000019423 pullulan Nutrition 0.000 claims 1
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP06119839.6 | 2006-08-30 | ||
| EP06119839A EP1897543A1 (en) | 2006-08-30 | 2006-08-30 | Buprenorphine- wafer for drug substitution therapy |
Related Parent Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2012273780A Division JP2013079265A (ja) | 2006-08-30 | 2012-12-14 | 薬物置換療法のためのブプレノルフィンウェハー |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2017108044A Division JP2017206517A (ja) | 2006-08-30 | 2017-05-31 | 薬物置換療法のためのブプレノルフィンウェハー |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2016006108A JP2016006108A (ja) | 2016-01-14 |
| JP2016006108A5 true JP2016006108A5 (enExample) | 2016-02-25 |
Family
ID=37685660
Family Applications (4)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2009526094A Pending JP2010501628A (ja) | 2006-08-30 | 2007-08-29 | 薬物置換療法のためのブプレノルフィンウェハー |
| JP2012273780A Pending JP2013079265A (ja) | 2006-08-30 | 2012-12-14 | 薬物置換療法のためのブプレノルフィンウェハー |
| JP2015162398A Pending JP2016006108A (ja) | 2006-08-30 | 2015-08-20 | 薬物置換療法のためのブプレノルフィンウェハー |
| JP2017108044A Pending JP2017206517A (ja) | 2006-08-30 | 2017-05-31 | 薬物置換療法のためのブプレノルフィンウェハー |
Family Applications Before (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2009526094A Pending JP2010501628A (ja) | 2006-08-30 | 2007-08-29 | 薬物置換療法のためのブプレノルフィンウェハー |
| JP2012273780A Pending JP2013079265A (ja) | 2006-08-30 | 2012-12-14 | 薬物置換療法のためのブプレノルフィンウェハー |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2017108044A Pending JP2017206517A (ja) | 2006-08-30 | 2017-05-31 | 薬物置換療法のためのブプレノルフィンウェハー |
Country Status (18)
| Country | Link |
|---|---|
| US (8) | US9101625B2 (enExample) |
| EP (2) | EP1897543A1 (enExample) |
| JP (4) | JP2010501628A (enExample) |
| AU (1) | AU2007291245A1 (enExample) |
| CA (1) | CA2661759C (enExample) |
| CY (1) | CY1114139T1 (enExample) |
| DE (1) | DE202006018608U1 (enExample) |
| DK (1) | DK2059243T3 (enExample) |
| ES (1) | ES2411179T3 (enExample) |
| HR (1) | HRP20130344T1 (enExample) |
| IL (1) | IL197316A (enExample) |
| ME (1) | ME02081B (enExample) |
| MX (1) | MX2009002196A (enExample) |
| PL (1) | PL2059243T3 (enExample) |
| PT (1) | PT2059243E (enExample) |
| RS (1) | RS52831B (enExample) |
| SI (1) | SI2059243T1 (enExample) |
| WO (1) | WO2008025791A1 (enExample) |
Families Citing this family (50)
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| US8900498B2 (en) | 2001-10-12 | 2014-12-02 | Monosol Rx, Llc | Process for manufacturing a resulting multi-layer pharmaceutical film |
| US11207805B2 (en) | 2001-10-12 | 2021-12-28 | Aquestive Therapeutics, Inc. | Process for manufacturing a resulting pharmaceutical film |
| US7357891B2 (en) | 2001-10-12 | 2008-04-15 | Monosol Rx, Llc | Process for making an ingestible film |
| US10285910B2 (en) | 2001-10-12 | 2019-05-14 | Aquestive Therapeutics, Inc. | Sublingual and buccal film compositions |
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| US8603514B2 (en) | 2002-04-11 | 2013-12-10 | Monosol Rx, Llc | Uniform films for rapid dissolve dosage form incorporating taste-masking compositions |
| US20190328679A1 (en) | 2001-10-12 | 2019-10-31 | Aquestive Therapeutics, Inc. | Uniform films for rapid-dissolve dosage form incorporating anti-tacking compositions |
| RU2504377C2 (ru) | 2006-07-21 | 2014-01-20 | БайоДеливери Сайенсиз Интэнэшнл, Инк. | Способ трансмукозальной доставки лекарства, средство трансмукозальной доставки лекарства (варианты) и способ лечения боли |
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-
2006
- 2006-08-30 EP EP06119839A patent/EP1897543A1/en not_active Withdrawn
- 2006-12-08 DE DE202006018608U patent/DE202006018608U1/de not_active Expired - Lifetime
-
2007
- 2007-08-29 HR HRP20130344TT patent/HRP20130344T1/hr unknown
- 2007-08-29 PL PL07802995T patent/PL2059243T3/pl unknown
- 2007-08-29 WO PCT/EP2007/058978 patent/WO2008025791A1/en not_active Ceased
- 2007-08-29 SI SI200731222T patent/SI2059243T1/sl unknown
- 2007-08-29 MX MX2009002196A patent/MX2009002196A/es unknown
- 2007-08-29 RS RS20130181A patent/RS52831B/sr unknown
- 2007-08-29 US US12/439,410 patent/US9101625B2/en active Active
- 2007-08-29 EP EP07802995A patent/EP2059243B1/en not_active Revoked
- 2007-08-29 DK DK07802995.6T patent/DK2059243T3/da active
- 2007-08-29 AU AU2007291245A patent/AU2007291245A1/en not_active Abandoned
- 2007-08-29 CA CA2661759A patent/CA2661759C/en not_active Expired - Fee Related
- 2007-08-29 ME MEP-2013-181A patent/ME02081B/me unknown
- 2007-08-29 ES ES07802995T patent/ES2411179T3/es active Active
- 2007-08-29 PT PT78029956T patent/PT2059243E/pt unknown
- 2007-08-29 JP JP2009526094A patent/JP2010501628A/ja active Pending
-
2009
- 2009-02-26 IL IL197316A patent/IL197316A/en active IP Right Grant
-
2012
- 2012-12-14 JP JP2012273780A patent/JP2013079265A/ja active Pending
-
2013
- 2013-04-25 CY CY20131100339T patent/CY1114139T1/el unknown
-
2014
- 2014-09-29 US US14/500,409 patent/US20150025102A1/en not_active Abandoned
-
2015
- 2015-07-15 US US14/800,270 patent/US9370512B2/en active Active
- 2015-08-20 JP JP2015162398A patent/JP2016006108A/ja active Pending
-
2016
- 2016-04-22 US US15/135,724 patent/US9763931B2/en not_active Expired - Fee Related
- 2016-04-22 US US15/135,794 patent/US9861628B2/en active Active
-
2017
- 2017-02-24 US US15/442,231 patent/US20170157062A1/en not_active Abandoned
- 2017-05-31 JP JP2017108044A patent/JP2017206517A/ja active Pending
- 2017-09-19 US US15/708,991 patent/US20180008595A1/en not_active Abandoned
-
2018
- 2018-08-17 US US15/998,868 patent/US20190216797A1/en not_active Abandoned
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