JP2016006053A5 - - Google Patents
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- Publication number
- JP2016006053A5 JP2016006053A5 JP2015134747A JP2015134747A JP2016006053A5 JP 2016006053 A5 JP2016006053 A5 JP 2016006053A5 JP 2015134747 A JP2015134747 A JP 2015134747A JP 2015134747 A JP2015134747 A JP 2015134747A JP 2016006053 A5 JP2016006053 A5 JP 2016006053A5
- Authority
- JP
- Japan
- Prior art keywords
- virus
- pharmaceutical composition
- composition according
- rotavirus
- coronavirus
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 239000008194 pharmaceutical composition Substances 0.000 claims 11
- 241000700605 Viruses Species 0.000 claims 9
- 241000711573 Coronaviridae Species 0.000 claims 3
- 241000711408 Murine respirovirus Species 0.000 claims 3
- 241000702670 Rotavirus Species 0.000 claims 3
- 150000001875 compounds Chemical class 0.000 claims 3
- 241000701161 unidentified adenovirus Species 0.000 claims 3
- 241001529453 unidentified herpesvirus Species 0.000 claims 3
- 241000709661 Enterovirus Species 0.000 claims 2
- 241000725643 Respiratory syncytial virus Species 0.000 claims 2
- YQNQNVDNTFHQSW-UHFFFAOYSA-N acetic acid [2-[[(5-nitro-2-thiazolyl)amino]-oxomethyl]phenyl] ester Chemical compound CC(=O)OC1=CC=CC=C1C(=O)NC1=NC=C([N+]([O-])=O)S1 YQNQNVDNTFHQSW-UHFFFAOYSA-N 0.000 claims 2
- 229960002480 nitazoxanide Drugs 0.000 claims 2
- 208000035473 Communicable disease Diseases 0.000 claims 1
- FDTZUTSGGSRHQF-UHFFFAOYSA-N Desacetyl-nitazoxanide Chemical compound OC1=CC=CC=C1C(=O)NC1=NC=C([N+]([O-])=O)S1 FDTZUTSGGSRHQF-UHFFFAOYSA-N 0.000 claims 1
- 208000036142 Viral infection Diseases 0.000 claims 1
- 230000009385 viral infection Effects 0.000 claims 1
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US17762609P | 2009-05-12 | 2009-05-12 | |
| US61/177,626 | 2009-05-12 |
Related Parent Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2012510917A Division JP5918124B2 (ja) | 2009-05-12 | 2010-05-11 | ハロアルキルヘテロアリールベンズアミド化合物 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2016006053A JP2016006053A (ja) | 2016-01-14 |
| JP2016006053A5 true JP2016006053A5 (enExample) | 2016-06-09 |
| JP6193922B2 JP6193922B2 (ja) | 2017-09-06 |
Family
ID=43069021
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2012510917A Active JP5918124B2 (ja) | 2009-05-12 | 2010-05-11 | ハロアルキルヘテロアリールベンズアミド化合物 |
| JP2015134747A Expired - Fee Related JP6193922B2 (ja) | 2009-05-12 | 2015-07-03 | ハロアルキルヘテロアリールベンズアミド化合物 |
Family Applications Before (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2012510917A Active JP5918124B2 (ja) | 2009-05-12 | 2010-05-11 | ハロアルキルヘテロアリールベンズアミド化合物 |
Country Status (24)
| Country | Link |
|---|---|
| US (4) | US8846727B2 (enExample) |
| EP (2) | EP2429986B1 (enExample) |
| JP (2) | JP5918124B2 (enExample) |
| KR (1) | KR101760956B1 (enExample) |
| CN (2) | CN105853415A (enExample) |
| AP (1) | AP3074A (enExample) |
| AU (2) | AU2010247816B2 (enExample) |
| BR (1) | BRPI1010547A2 (enExample) |
| CA (2) | CA2761876C (enExample) |
| CL (1) | CL2011002830A1 (enExample) |
| CO (1) | CO6460766A2 (enExample) |
| CR (1) | CR20110607A (enExample) |
| DO (1) | DOP2011000353A (enExample) |
| EA (1) | EA021587B1 (enExample) |
| EC (1) | ECSP11011511A (enExample) |
| HK (1) | HK1223819A1 (enExample) |
| HN (1) | HN2011003002A (enExample) |
| IL (2) | IL216331B (enExample) |
| MX (1) | MX337460B (enExample) |
| NI (1) | NI201100199A (enExample) |
| NZ (1) | NZ596538A (enExample) |
| PE (1) | PE20121118A1 (enExample) |
| SG (2) | SG176045A1 (enExample) |
| WO (1) | WO2010132404A1 (enExample) |
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| EP2739611B1 (de) * | 2011-08-03 | 2015-05-13 | Bayer Intellectual Property GmbH | N-(tetrazol-5-yl)- und n-(triazol-5-yl)arylcarbonsäureamide und ihre verwendung als herbizide |
| ES2882807T3 (es) | 2011-09-16 | 2021-12-02 | Novartis Ag | Heterociclil carboxamidas N-sustituidas |
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| US9938236B2 (en) * | 2012-12-27 | 2018-04-10 | Drexel University | Antiviral agents against HBV infection |
| JP6371077B2 (ja) * | 2014-02-25 | 2018-08-08 | 国立大学法人佐賀大学 | ジフルオロメチル基含有化合物及びその用途 |
| EP3140298A1 (en) | 2014-05-07 | 2017-03-15 | Pfizer Inc. | Tropomyosin-related kinase inhibitors |
| BR112017009651A2 (pt) | 2014-11-11 | 2017-12-19 | Romark Laboratories Lc | composto, composição farmacêutica, e, método para tratamento de uma infecção por protozoário intracelular, uma infecção viral ou um câncer. |
| EP3227284B1 (en) | 2014-12-01 | 2021-04-28 | Syngenta Participations AG | Pesticidally active amide heterocyclic derivatives with sulphur containing substituents |
| MX384836B (es) | 2016-03-07 | 2025-03-14 | Enanta Pharm Inc | Agentes antivirales contra la hepatitis b |
| PT3436074T (pt) | 2016-03-31 | 2020-08-21 | Romark Laboratories Lc | Compostos tiazolida para tratamento de infeções virais |
| SG11201808402RA (en) | 2016-04-11 | 2018-10-30 | Genfit | Methods of treatment for cholestatic and fibrotic diseases |
| BR112019012822A2 (pt) | 2016-12-22 | 2019-11-26 | Bayer Ag | 1,2,4-tiadiazolilpirrolonas e 1,2,4-tiadiazolil-hidantoínas e sais das mesmas e uso das mesmas como herbicidas |
| US11173149B2 (en) | 2017-04-18 | 2021-11-16 | Romark Laboratories L.C. | Inhibition of protein disulfide-isomerase A3 |
| NZ762994A (en) | 2017-08-28 | 2025-11-28 | Enanta Pharm Inc | Hepatitis b antiviral agents |
| KR20210095143A (ko) | 2018-10-22 | 2021-07-30 | 어셈블리 바이오사이언시스, 인크. | Hbv의 치료를 위한 5원 헤테로아릴 카르복스아미드 화합물 |
| SG11202105007TA (en) | 2018-11-21 | 2021-06-29 | Enanta Pharm Inc | Functionalized heterocycles as antiviral agents |
| MX2022000278A (es) * | 2019-07-19 | 2022-02-03 | Abivax | Derivados de aril-n-arilo para tratar una infeccion por virus de acido ribonucleico (arn). |
| WO2021016543A1 (en) * | 2019-07-25 | 2021-01-28 | Romark Laboratories L.C. | Antiviral combinations of thiazolide compounds |
| JP7386576B2 (ja) * | 2019-10-02 | 2023-11-27 | カイノス・メディスン・インコーポレイテッド | Ｎ－（１ｈ－イミダゾール－２－イル）ベンズアミド化合物および該化合物を活性成分として含む医薬組成物 |
| EP4101449A4 (en) * | 2020-01-21 | 2024-02-21 | Academy of Military Medical Sciences | Application of nitazoxanide and active form thereof, tizoxanide, in treatment of sars-cov-2 infection |
| CN111187215B (zh) * | 2020-01-21 | 2023-02-24 | 西北农林科技大学 | 含氟吡唑酰胺类衍生物、制备方法及其应用 |
| US20230241037A1 (en) * | 2020-03-09 | 2023-08-03 | 1Globe Health Institute, Nanjing | Cross-linked medication for treatment of coronaviral infection and method of treatment |
| CN113398125B (zh) | 2020-03-16 | 2024-05-03 | 绍兴君科臻元医药科技有限公司 | 替唑尼特药物组合物及其医药用途 |
| WO2021188414A1 (en) | 2020-03-16 | 2021-09-23 | Enanta Pharmaceuticals, Inc. | Functionalized heterocyclic compounds as antiviral agents |
| EP4182304A1 (en) | 2020-07-20 | 2023-05-24 | Romark Laboratories, L.C. | Crystalline salts of tizoxanide and 2-hydroxy-n-(5-chloro-1,3-thiazol-2-yl)benzamide (rm-4848) with ethanolamine, morpholine, propanolamine, piperazine and n-methylpiperazine |
| JP2023538136A (ja) | 2020-08-24 | 2023-09-06 | ロマーク ラボラトリーズ，リミティド カンパニー | コロナウイルスに対するチアゾリドの利用 |
| US20230373930A1 (en) * | 2020-10-09 | 2023-11-23 | Bristol-Myers Squibb Company | Aminoimidazole fpr2 agonists |
| US20240002332A1 (en) * | 2020-11-18 | 2024-01-04 | Wenwei HUANG | Small Molecule Inhibitors of SARS-CoV-2 Infections |
| WO2022130406A1 (en) * | 2020-12-15 | 2022-06-23 | Cipla Limited | Inhalation composition of nitazoxanide or its derivatives for use in coronavirus disease |
| US12146029B1 (en) | 2021-02-08 | 2024-11-19 | Futurefuel Chemical Company | Polymers enhanced with hydrated sodium sulfoisophthalic acid salts |
| CN116003323B (zh) * | 2023-02-14 | 2023-12-08 | 西北农林科技大学 | 含氟吡唑苯乙酰胺类衍生物及其应用 |
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-
2010
- 2010-05-11 EA EA201171378A patent/EA021587B1/ru not_active IP Right Cessation
- 2010-05-11 NZ NZ596538A patent/NZ596538A/en not_active IP Right Cessation
- 2010-05-11 US US12/777,383 patent/US8846727B2/en active Active
- 2010-05-11 AU AU2010247816A patent/AU2010247816B2/en not_active Ceased
- 2010-05-11 EP EP10775367.5A patent/EP2429986B1/en not_active Not-in-force
- 2010-05-11 CN CN201610225952.2A patent/CN105853415A/zh active Pending
- 2010-05-11 BR BRPI1010547-6A patent/BRPI1010547A2/pt not_active Application Discontinuation
- 2010-05-11 EP EP16167043.5A patent/EP3078377A3/en not_active Withdrawn
- 2010-05-11 CA CA2761876A patent/CA2761876C/en not_active Expired - Fee Related
- 2010-05-11 WO PCT/US2010/034319 patent/WO2010132404A1/en not_active Ceased
- 2010-05-11 PE PE2011001963A patent/PE20121118A1/es not_active Application Discontinuation
- 2010-05-11 JP JP2012510917A patent/JP5918124B2/ja active Active
- 2010-05-11 CA CA2940954A patent/CA2940954A1/en not_active Abandoned
- 2010-05-11 SG SG2011083573A patent/SG176045A1/en unknown
- 2010-05-11 KR KR1020117029247A patent/KR101760956B1/ko not_active Expired - Fee Related
- 2010-05-11 SG SG10201402281WA patent/SG10201402281WA/en unknown
- 2010-05-11 CN CN201080031243.1A patent/CN102803203B/zh not_active Expired - Fee Related
- 2010-05-11 AP AP2011006015A patent/AP3074A/xx active
- 2010-05-11 MX MX2011012040A patent/MX337460B/es active IP Right Grant
-
2011
- 2011-11-11 CL CL2011002830A patent/CL2011002830A1/es unknown
- 2011-11-11 NI NI201100199A patent/NI201100199A/es unknown
- 2011-11-11 HN HN2011003002A patent/HN2011003002A/es unknown
- 2011-11-13 IL IL216331A patent/IL216331B/en active IP Right Grant
- 2011-11-14 DO DO2011000353A patent/DOP2011000353A/es unknown
- 2011-11-15 CO CO11154944A patent/CO6460766A2/es not_active Application Discontinuation
- 2011-11-18 CR CR20110607A patent/CR20110607A/es unknown
- 2011-12-09 EC ECSP11011511 patent/ECSP11011511A/es unknown
-
2014
- 2014-08-05 US US14/451,637 patent/US9126992B2/en not_active Ceased
-
2015
- 2015-07-03 JP JP2015134747A patent/JP6193922B2/ja not_active Expired - Fee Related
- 2015-07-27 IL IL240167A patent/IL240167A0/en unknown
-
2016
- 2016-04-18 AU AU2016202439A patent/AU2016202439B2/en not_active Ceased
- 2016-05-17 US US15/156,580 patent/USRE46724E1/en active Active
- 2016-09-22 HK HK16111122.0A patent/HK1223819A1/zh unknown
-
2018
- 2018-01-08 US US15/864,411 patent/USRE47786E1/en active Active
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