|
US4711955A
(en)
|
1981-04-17 |
1987-12-08 |
Yale University |
Modified nucleotides and methods of preparing and using same
|
|
US4603112A
(en)
|
1981-12-24 |
1986-07-29 |
Health Research, Incorporated |
Modified vaccinia virus
|
|
US4596556A
(en)
|
1985-03-25 |
1986-06-24 |
Bioject, Inc. |
Hypodermic injection apparatus
|
|
FI861417A0
(fi)
|
1985-04-15 |
1986-04-01 |
Endotronics Inc |
Hepatitis b ytantigen framstaelld med rekombinant-dna-teknik, vaccin, diagnostiskt medel och cellinjer samt foerfaranden foer framstaellning daerav.
|
|
FR2583429B1
(fr)
|
1985-06-18 |
1989-11-03 |
Transgene Sa |
Vecteur d'expression de l'interferon u dans les cellules de mammifere, procede pour sa mise en oeuvre et produit obtenu et composition pharmaceutique contenant l'interferon u
|
|
FR2606029B2
(fr)
|
1986-04-08 |
1989-02-03 |
Transgene Sa |
Vecteur viral et adn recombinant codant pour une glycoproteine du virus agent causal du s.i.d.a., culture cellulaire infectee par ce vecteur, procede de preparation de la glycoproteine, glycoproteine obtenue, vaccin et anticorps obtenus
|
|
FR2643817B1
(fr)
|
1989-03-06 |
1993-12-17 |
Transgene Sa |
Composition pharmaceutique, utile a titre preventif ou curatif contre les tumeurs induites par les papillomavirus
|
|
EP1088830A3
(en)
|
1987-06-22 |
2004-04-07 |
Medeva Holdings B.V. |
Hepatitis b surface antigen particles
|
|
US4873316A
(en)
|
1987-06-23 |
1989-10-10 |
Biogen, Inc. |
Isolation of exogenous recombinant proteins from the milk of transgenic mammals
|
|
FR2632863B2
(fr)
|
1987-10-29 |
1990-08-31 |
Transgene Sa |
Virus du fowlpox recombinant et vaccins derives de ces virus
|
|
GB8819209D0
(en)
|
1988-08-12 |
1988-09-14 |
Research Corp Ltd |
Polypeptide & dna encoding same
|
|
DK0414374T3
(da)
|
1989-07-25 |
1998-03-09 |
Smithkline Beecham Biolog |
Hidtil ukendte antigener og fremgangsmåder til fremstilling deraf
|
|
FR2650838A1
(fr)
|
1989-08-09 |
1991-02-15 |
Transgene Sa |
Vecteurs d'expression du facteur ix dans une cellule eucaryote superieure, procede de preparation de facteur ix par des animaux transgeniques et facteur ix obtenu
|
|
US5108910A
(en)
|
1989-08-22 |
1992-04-28 |
Immunex Corporation |
DNA sequences encoding fusion proteins comprising GM-CSF and IL-3
|
|
US5670488A
(en)
|
1992-12-03 |
1997-09-23 |
Genzyme Corporation |
Adenovirus vector for gene therapy
|
|
FR2668064B1
(fr)
|
1990-10-23 |
1994-12-16 |
Transgene Sa |
Composition pharmaceutique pour le traitement ou la prevention d'une tumeur maligne.
|
|
GB9105383D0
(en)
|
1991-03-14 |
1991-05-01 |
Immunology Ltd |
An immunotherapeutic for cervical cancer
|
|
DE122007000023I1
(de)
|
1991-07-19 |
2007-08-09 |
Univ Queensland St Lucia |
Impfsstoff gegen Humanes Papillomavirus (typ 18)
|
|
ES2129461T3
(es)
|
1991-11-16 |
1999-06-16 |
Smithkline Beecham Biolog |
Proteina hibrida entre cs de plasmodium y hbsag.
|
|
EP0647140B1
(en)
|
1992-06-25 |
2007-12-12 |
Georgetown University |
Papillomavirus vaccines
|
|
US5786148A
(en)
|
1996-11-05 |
1998-07-28 |
Incyte Pharmaceuticals, Inc. |
Polynucleotides encoding a novel prostate-specific kallikrein
|
|
GB9223084D0
(en)
|
1992-11-04 |
1992-12-16 |
Imp Cancer Res Tech |
Compounds to target cells
|
|
EP1024198A3
(en)
|
1992-12-03 |
2002-05-29 |
Genzyme Corporation |
Pseudo-adenoviral vectors for the gene therapy of haemophiliae
|
|
US5747323A
(en)
|
1992-12-31 |
1998-05-05 |
Institut National De La Sante Et De La Recherche Medicale (Inserm) |
Retroviral vectors comprising a VL30-derived psi region
|
|
US5801029A
(en)
|
1993-02-16 |
1998-09-01 |
Onyx Pharmaceuticals, Inc. |
Cytopathic viruses for therapy and prophylaxis of neoplasia
|
|
ES2242955T4
(es)
|
1993-03-09 |
2010-04-12 |
The University Of Rochester |
Produccion de la proteina de la capside del virus del papiloma humano y particulas de tipo viral.
|
|
FR2705686B1
(fr)
|
1993-05-28 |
1995-08-18 |
Transgene Sa |
Nouveaux adénovirus défectifs et lignées de complémentation correspondantes.
|
|
US6133028A
(en)
|
1993-05-28 |
2000-10-17 |
Transgene S.A. |
Defective adenoviruses and corresponding complementation lines
|
|
FR2707091B1
(fr)
|
1993-06-30 |
1997-04-04 |
Cohen Haguenauer Odile |
Vecteur rétroviral pour le transfert et l'expression de gènes dans des cellules eucaryotes.
|
|
FR2711523B1
(fr)
|
1993-10-26 |
1996-02-16 |
Transgene Sa |
Procédé de préparation d'un aérosol viral.
|
|
US5698443A
(en)
|
1995-06-27 |
1997-12-16 |
Calydon, Inc. |
Tissue specific viral vectors
|
|
US5635599A
(en)
*
|
1994-04-08 |
1997-06-03 |
The United States Of America As Represented By The Department Of Health And Human Services |
Fusion proteins comprising circularly permuted ligands
|
|
US5525711A
(en)
|
1994-05-18 |
1996-06-11 |
The United States Of America As Represented By The Secretary Of The Department Of Health And Human Services |
Pteridine nucleotide analogs as fluorescent DNA probes
|
|
WO1995032299A1
(en)
|
1994-05-20 |
1995-11-30 |
The Board Of Trustees Of The Leland Stanford Junior University |
An autonomous replication system for mammalian cells
|
|
US5998205A
(en)
|
1994-11-28 |
1999-12-07 |
Genetic Therapy, Inc. |
Vectors for tissue-specific replication
|
|
US6638762B1
(en)
|
1994-11-28 |
2003-10-28 |
Genetic Therapy, Inc. |
Tissue-vectors specific replication and gene expression
|
|
FR2727689A1
(fr)
|
1994-12-01 |
1996-06-07 |
Transgene Sa |
Nouveau procede de preparation d'un vecteur viral
|
|
FR2730735B1
(fr)
|
1995-02-20 |
1997-05-09 |
Pasteur Institut |
Sequences amplificatrices, vecteurs portant ces sequences et leurs utilisations dans des compositions pour l'expression de sequences nucleotidiques dans des cellules transfectees, applications therapeutiques et vaccinales
|
|
US5837520A
(en)
|
1995-03-07 |
1998-11-17 |
Canji, Inc. |
Method of purification of viral vectors
|
|
US5759776A
(en)
|
1995-06-05 |
1998-06-02 |
California Pacific Medical Center |
Targets for breast cancer diagnosis and treatment
|
|
WO1996040958A1
(en)
|
1995-06-07 |
1996-12-19 |
Baylor College Of Medicine |
Nucleic acid transporters for delivery of nucleic acids into a cell
|
|
UA68327C2
(en)
|
1995-07-04 |
2004-08-16 |
Gsf Forschungszentrum Fur Unwe |
A recombinant mva virus, an isolated eukaryotic cell, infected with recombinant mva virus, a method for production in vitro of polypeptides with use of said cell, a method for production in vitro of virus parts (variants), vaccine containing the recombinant mva virus, a method for immunization of animals
|
|
FR2737222B1
(fr)
|
1995-07-24 |
1997-10-17 |
Transgene Sa |
Nouveaux vecteurs viraux et lignee pour la therapie genique
|
|
US6090618A
(en)
|
1996-10-07 |
2000-07-18 |
Arch Development Corporation |
DNA constructs and viral vectors comprising a smooth muscle promoter
|
|
US6225446B1
(en)
*
|
1995-12-06 |
2001-05-01 |
Schering Corporation |
Mutational variants of mammalian proteins
|
|
FR2746815A1
(fr)
|
1996-03-26 |
1997-10-03 |
Pasteur Institut |
Sequences en amont du gene sm 22, vecteurs les contenant et leurs utilisations therapeutiques, notamment dans le traitement des maladies vasculaires
|
|
US5776683A
(en)
|
1996-07-11 |
1998-07-07 |
California Pacific Medical Center |
Methods for identifying genes amplified in cancer cells
|
|
JP2000514290A
(ja)
|
1996-07-01 |
2000-10-31 |
ローヌ―プーラン・ロレ・エス・アー |
組換えアデノウイルスの製造方法
|
|
JP2001500015A
(ja)
|
1996-09-06 |
2001-01-09 |
トラステイーズ・オブ・ザ・ユニバーシテイ・オブ・ペンシルベニア |
T7ポリメラーゼを利用する組換えアデノ随伴ウイルスの誘導可能な製造方法
|
|
US5955306A
(en)
|
1996-09-17 |
1999-09-21 |
Millenium Pharmaceuticals, Inc. |
Genes encoding proteins that interact with the tub protein
|
|
US5994132A
(en)
|
1996-10-23 |
1999-11-30 |
University Of Michigan |
Adenovirus vectors
|
|
JP4492826B2
(ja)
|
1996-11-20 |
2010-06-30 |
イントロジェン セラピューティクス,インコーポレイテッド |
アデノウイルスベクターの産生および精製のための改良された方法
|
|
DE69739961D1
(de)
|
1996-12-13 |
2010-09-23 |
Schering Corp |
Methoden zur Virus-Reinigung
|
|
US5993412A
(en)
|
1997-05-19 |
1999-11-30 |
Bioject, Inc. |
Injection apparatus
|
|
FR2763958A1
(fr)
|
1997-05-29 |
1998-12-04 |
Transgene Sa |
Produit de combinaison associant un acide nucleique a une substance desorganisant la matrice extracellulaire pour la therapie genique
|
|
FR2763959A1
(fr)
|
1997-06-02 |
1998-12-04 |
Transgene Sa |
Nouveaux vecteurs adenoviraux recombinants comprenant une sequence d'epissage
|
|
WO1998056415A1
(en)
|
1997-06-11 |
1998-12-17 |
Aquila Biopharmaceuticals, Inc. |
Purified saponins as oral adjuvants
|
|
AU707186B2
(en)
|
1997-07-01 |
1999-07-01 |
Transgene S.A. |
Compositions useful for transferring therapeutically active substances into a target cell, and their use in gene therapy
|
|
FR2766091A1
(fr)
|
1997-07-18 |
1999-01-22 |
Transgene Sa |
Composition antitumorale a base de polypeptide immunogene de localisation cellulaire modifiee
|
|
WO2000046355A2
(en)
|
1999-02-04 |
2000-08-10 |
Geron Corporation |
Telomerase reverse transcriptase transcriptional regulatory sequences
|
|
WO1999027113A1
(en)
|
1997-11-26 |
1999-06-03 |
Geron Corporation |
Mouse telomerase reverse transcriptase
|
|
NZ504894A
(en)
|
1997-12-02 |
2002-12-20 |
Powderject Vaccines Inc |
Crystalline vaccine and adjuvant compositions jointly and separately administered to animals using a transdermal or transmucosally delivery technique
|
|
CN1227360C
(zh)
|
1998-02-05 |
2005-11-16 |
史密丝克莱恩比彻姆生物有限公司 |
Mage家族肿瘤相关抗原衍生物及其编码核酸序列
|
|
CA2326739A1
(en)
|
1998-04-02 |
1999-10-14 |
The Regents Of The University Of California |
Methods for enhancing antigen-presenting cells and anti-tumor responses in a human patient
|
|
US6838081B1
(en)
|
1998-04-02 |
2005-01-04 |
The Regents Of The University Of California |
Methods for enhancing antigen-presenting cells and anti-tumor responses in a human patient
|
|
AU3560399A
(en)
|
1998-04-15 |
1999-11-01 |
Ludwig Institute For Cancer Research |
Tumor associated nucleic acids and uses therefor
|
|
CA2295510A1
(en)
|
1998-05-06 |
1999-11-11 |
Transgene S.A. |
Use of a nuclease inhibitor or interleukin-10 (il-10) for the preparation of a therapeutic composition for improving transfection of a polynucleotide into a cell and compositions useful in gene therapy
|
|
CN1107604C
(zh)
*
|
1998-05-15 |
2003-05-07 |
李振东 |
防夜间会车眩目的后灯侧灯车体灯
|
|
JP3864610B2
(ja)
|
1998-05-21 |
2007-01-10 |
旭硝子株式会社 |
水分散型撥水撥油剤組成物およびその製造方法
|
|
DK1199368T3
(da)
|
1998-07-07 |
2004-04-13 |
Transgene Sa |
Anvendelse af adenovirus-E4-læserammer til forbedring af ekspression af et gen af interesse
|
|
TW200728465A
(en)
|
1998-07-14 |
2007-08-01 |
Corixa Corp |
Compositions and methods for the therapy and diagnosis of prostate cancer
|
|
FR2782732A1
(fr)
|
1998-08-28 |
2000-03-03 |
Transgene Sa |
Systeme d'expression inductible
|
|
US6900049B2
(en)
|
1998-09-10 |
2005-05-31 |
Cell Genesys, Inc. |
Adenovirus vectors containing cell status-specific response elements and methods of use thereof
|
|
EP0998945A1
(en)
|
1998-09-30 |
2000-05-10 |
Transgene S.A. |
Use of magnesium (Mg2+) for the enhancement of gene delivery in gene therapy
|
|
US20020037274A1
(en)
|
1998-10-26 |
2002-03-28 |
Angelica Williams |
Single agent method for killing tumor and tumor associated endothelial cells using adenoviral mutants
|
|
US7217421B1
(en)
|
1998-11-03 |
2007-05-15 |
Cell Genesys, Inc. |
Cancer-associated antigens and methods of their identification and use
|
|
FR2787465A1
(fr)
|
1998-12-21 |
2000-06-23 |
Transgene Sa |
Procede d'inactivation des virus enveloppes dans une preparation virale de virus non enveloppes
|
|
CN1258738A
(zh)
*
|
1998-12-31 |
2000-07-05 |
上海华晨生物技术研究所 |
表达人粒细胞巨噬细胞集落刺激因子的重组腺病毒及其制法和用途
|
|
CZ20012428A3
(cs)
|
1998-12-31 |
2001-11-14 |
Aventis Pharma S. A. |
Způsob separace virových částic
|
|
DE60029195T2
(de)
|
1999-02-22 |
2007-06-28 |
Transgene S.A. |
Verfahren zur Gewinnung von purifizierter Virenzusammensetzung
|
|
US6492169B1
(en)
|
1999-05-18 |
2002-12-10 |
Crucell Holland, B.V. |
Complementing cell lines
|
|
ATE316982T1
(de)
|
1999-08-09 |
2006-02-15 |
Lexigen Pharm Corp |
Mehrere zytokin-antikörper komplexen
|
|
DK1230378T3
(da)
|
1999-11-15 |
2007-10-08 |
Onyx Pharma Inc |
Et onkolytisk adenovirus
|
|
WO2001047563A1
(en)
|
1999-12-28 |
2001-07-05 |
Transgene S.A. |
Use of lithium (li+) for the preparation of a composition for transfection of a polynucleotide into a cell and compositions useful in gene therapy
|
|
CA2341356C
(en)
|
2000-04-14 |
2011-10-11 |
Transgene S.A. |
Poxvirus with targeted infection specificity
|
|
AU2002230958A1
(en)
|
2000-12-18 |
2002-07-16 |
Geron Corporation |
Chimeric cytolytic viruses for cancer treatment
|
|
EP1390398A2
(en)
|
2001-05-30 |
2004-02-25 |
Transgene S.A. |
Adenovirus protein ix, its domains involved in capsid assembly, transcriptional activity and nuclear reorganization
|
|
AU2002335973A1
(en)
*
|
2001-10-23 |
2003-05-06 |
Centre For Translational Research In Cancer |
A synthetic chimeric fusion protein with immuno-therapeutic uses
|
|
EP1310561A1
(en)
|
2001-11-09 |
2003-05-14 |
Transgene S.A. |
Chimeric promoters for controlling expression in skeletal muscle cells
|
|
GB0201679D0
(en)
*
|
2002-01-25 |
2002-03-13 |
Asterion Ltd |
Polypeptide variants
|
|
US20050053777A1
(en)
|
2003-09-06 |
2005-03-10 |
Hilliard Donald Bennett |
Pellicle
|
|
FR2862866B1
(fr)
|
2003-11-28 |
2006-12-15 |
Gilles Voydeville |
Prothese discale intervertebrale postero-laterale
|
|
DK1699822T3
(da)
|
2003-12-30 |
2008-08-04 |
Merck Patent Gmbh |
IL-7-fusionsproteiner med antistofdele, fremstilling deraf og anvendelse deraf
|
|
ES2424229T3
(es)
*
|
2005-03-18 |
2013-09-30 |
Cytos Biotechnology Ag |
Proteínas de fusión de alérgenos de gato y utilización de las mismas
|
|
EP2052081A1
(en)
|
2006-08-02 |
2009-04-29 |
McGill University |
Fusion proteins and methods for modulation of immune response
|
|
WO2008053573A1
(fr)
|
2006-10-30 |
2008-05-08 |
National University Corporation Hokkaido University |
Remède pour néoplasme malin
|
|
US20100278873A1
(en)
*
|
2007-11-08 |
2010-11-04 |
David Avigan |
Stimulation of anti-tumor immunity using dendritic cell/tumor cell fusions and anti-cd3/cd28
|
|
EP2360204B1
(en)
|
2008-11-21 |
2016-09-28 |
DIC Corporation |
Method for manufacturing polyarylene sulfide resin
|
|
US9539320B2
(en)
*
|
2009-05-15 |
2017-01-10 |
Irx Therapeutics, Inc. |
Vaccine immunotherapy
|
|
JP2013537172A
(ja)
*
|
2010-09-09 |
2013-09-30 |
トリフォイリウム エーピーエス |
血管新生阻害剤の気道投与
|
|
WO2014066443A1
(en)
*
|
2012-10-23 |
2014-05-01 |
Emory University |
Gm-csf and il-4 conjugates, compositions, and methods related thereto
|