CN104870477B - Gm-csf和il-4轭合物、组合物以及与其相关的方法 - Google Patents

Gm-csf和il-4轭合物、组合物以及与其相关的方法 Download PDF

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CN104870477B
CN104870477B CN201380066094.6A CN201380066094A CN104870477B CN 104870477 B CN104870477 B CN 104870477B CN 201380066094 A CN201380066094 A CN 201380066094A CN 104870477 B CN104870477 B CN 104870477B
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cells
gift4
antigen
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CN104870477A (zh
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雅克·加利波
九生·邓
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Emory University
Childrens Healthcare of Atlanta Inc
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Childrens Healthcare of Atlanta Inc
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    • C07K14/52—Cytokines; Lymphokines; Interferons
    • C07K14/54—Interleukins [IL]
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CN201380066094.6A 2012-10-23 2013-10-23 Gm-csf和il-4轭合物、组合物以及与其相关的方法 Expired - Fee Related CN104870477B (zh)

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EP (2) EP2912069B1 (OSRAM)
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WO2014066443A1 (en) 2012-10-23 2014-05-01 Emory University Gm-csf and il-4 conjugates, compositions, and methods related thereto
US10072058B2 (en) 2015-04-29 2018-09-11 Emory University Chimeric virus-like particles incorporating fusion GPI anchored GM-CSF and IL-4 conjugates
WO2017027866A1 (en) * 2015-08-13 2017-02-16 University Of Florida Research Foundation, Inc. Aav6 vectors for immunotherapy
CN105647970A (zh) * 2016-02-22 2016-06-08 河北利同康生物科技有限公司 前列腺癌特异性pap-gm-csf-il-6基因重组融合蛋白及其制备方法
EP3430148A4 (en) * 2016-03-18 2020-01-01 Nantcell, Inc. MULTIMODAL VECTOR FOR DENDRITIC CELL INFECTION
US11267859B2 (en) * 2017-06-09 2022-03-08 The Regents Of The University Of Colorado, A Body Corporate GM-CSF mimetics and methods of making and using same
CN109735566B (zh) * 2018-12-13 2023-02-28 中国科学院广州生物医药与健康研究院 一种增强腺病毒载体生物制品感染靶细胞的方法
EP3955955B1 (en) 2019-04-19 2025-02-26 Synerkine Pharma B.V. A fusion protein comprising il13
WO2021188883A1 (en) * 2020-03-20 2021-09-23 The Regents Of The University Of Colorado, A Body Corporate Methods and compositions for the treatment of viral disease using granulocyte-macrophage colony-stimulating factor (gm-csf)
EP4422671A1 (en) * 2021-10-25 2024-09-04 Ellennbe GmbH Pharmaceutical composition and kit comprising an immunomodulatory substance for treating diseases
WO2024112814A1 (en) * 2022-11-21 2024-05-30 Wisconsin Alumni Research Foundation SYNTHETIC IL6-IL1β FUSION CYTOKINE FOR PROMOTING T CELL CYTOTOXIC FUNCTION, T CELL PROLIFERATION, AND TUMORICIDAL ACTIVITY

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