DE69739961D1 - Methoden zur Virus-Reinigung - Google Patents

Methoden zur Virus-Reinigung

Info

Publication number
DE69739961D1
DE69739961D1 DE69739961T DE69739961T DE69739961D1 DE 69739961 D1 DE69739961 D1 DE 69739961D1 DE 69739961 T DE69739961 T DE 69739961T DE 69739961 T DE69739961 T DE 69739961T DE 69739961 D1 DE69739961 D1 DE 69739961D1
Authority
DE
Germany
Prior art keywords
methods
virus cleaning
virus
cleaning
purifying
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE69739961T
Other languages
English (en)
Inventor
John Chu-Tay Tang
Gary J Vellekamp
Laureano L Bondoc Jr
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Merck Sharp and Dohme Corp
Original Assignee
Schering Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Schering Corp filed Critical Schering Corp
Application granted granted Critical
Publication of DE69739961D1 publication Critical patent/DE69739961D1/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N7/00—Viruses; Bacteriophages; Compositions thereof; Preparation or purification thereof
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2710/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA dsDNA viruses
    • C12N2710/00011—Details
    • C12N2710/10011—Adenoviridae
    • C12N2710/10051—Methods of production or purification of viral material
DE69739961T 1996-12-13 1997-12-11 Methoden zur Virus-Reinigung Expired - Lifetime DE69739961D1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US76683596A 1996-12-13 1996-12-13

Publications (1)

Publication Number Publication Date
DE69739961D1 true DE69739961D1 (de) 2010-09-23

Family

ID=25077670

Family Applications (2)

Application Number Title Priority Date Filing Date
DE69739961T Expired - Lifetime DE69739961D1 (de) 1996-12-13 1997-12-11 Methoden zur Virus-Reinigung
DE69737364T Expired - Lifetime DE69737364T2 (de) 1996-12-13 1997-12-11 Methoden zur virus-reinigung

Family Applications After (1)

Application Number Title Priority Date Filing Date
DE69737364T Expired - Lifetime DE69737364T2 (de) 1996-12-13 1997-12-11 Methoden zur virus-reinigung

Country Status (9)

Country Link
EP (2) EP0948601B1 (de)
JP (3) JP2001506126A (de)
AT (2) ATE477320T1 (de)
AU (1) AU5370598A (de)
CA (1) CA2274876A1 (de)
DE (2) DE69739961D1 (de)
ES (2) ES2283032T3 (de)
IL (1) IL130198A (de)
WO (1) WO1998026048A1 (de)

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US7732129B1 (en) * 1998-12-01 2010-06-08 Crucell Holland B.V. Method for the production and purification of adenoviral vectors
ES2278399T3 (es) 1996-11-20 2007-08-01 Introgen Therapeutics, Inc. Metodo mejorado para la produccion y purificacion de vectores adenovirales.
US6689600B1 (en) 1998-11-16 2004-02-10 Introgen Therapeutics, Inc. Formulation of adenovirus for gene therapy
FR2787465A1 (fr) * 1998-12-21 2000-06-23 Transgene Sa Procede d'inactivation des virus enveloppes dans une preparation virale de virus non enveloppes
US7264958B1 (en) 1999-02-22 2007-09-04 Transgene, S.A. Method for obtaining a purified viral preparation
SE9904272D0 (sv) * 1999-11-25 1999-11-25 Amersham Pharm Biotech Ab A method for selective removal of a substance from samples containing compounds having nucleic acid structure
EP1501921B2 (de) 2002-04-30 2012-07-25 Oncolytics Biotech Inc. Verbesserte reinigungsmethode für viren
CA2531773A1 (en) 2003-07-21 2005-02-17 Transgene S.A. Novel multifunctional cytokines
US7901921B2 (en) 2004-10-22 2011-03-08 Oncolytics Biotech Inc. Viral purification methods
CN101080488A (zh) 2004-11-03 2007-11-28 因特罗根治疗公司 生产和纯化腺病毒载体的新方法
WO2008039136A1 (en) 2006-09-29 2008-04-03 Ge Healthcare Bio-Sciences Ab Separation matrix for viral purification
PL2118292T3 (pl) 2007-01-30 2011-12-30 Transgene Sa Polipeptyd E2 wirusa brodawczaka stosowany do szczepienia
JP2010193720A (ja) * 2009-02-23 2010-09-09 Asahi Kasei Chemicals Corp アニオン交換基が固定された多孔膜を用いたウイルスの分離方法
MX2012001592A (es) 2009-08-07 2012-05-22 Transgene Sa Composicion para el tratamiento de la infección del virus de la hepatitis b.
GB201011502D0 (en) * 2010-07-08 2010-08-25 Glaxosmithkline Biolog Sa Novel process
CN103476928B (zh) 2010-12-09 2017-03-29 巴斯德研究所 用于获得高产量重组蛋白表达的基于mgmt的方法
TWI575070B (zh) 2011-07-12 2017-03-21 傳斯堅公司 Ｈｂｖ聚合酶突變體
TW201321016A (zh) 2011-09-29 2013-06-01 Transgene Sa 免疫療法組成物及用於治療ｃ型肝炎病毒感染之療程（二）
WO2013045658A1 (en) 2011-09-29 2013-04-04 Transgene Sa Immunotherapy composition and regimen for treating hepatitis c virus infection
RU2015114330A (ru) 2012-09-17 2016-11-10 У.Р. Грейс Энд Ко.-Конн. Хроматографические среды и устройства
JP6430949B2 (ja) 2012-10-23 2018-11-28 エモリー ユニバーシティ Ｇｍ−ｃｓｆとｉｌ−４のコンジュゲート、組成物、ならびにそれに関連する方法
WO2016131945A1 (en) 2015-02-20 2016-08-25 Transgene Sa Combination product with autophagy modulator
US20190134190A1 (en) 2016-05-04 2019-05-09 Transgene Sa Combination therapy with cpg tlr9 ligand
US20190328869A1 (en) 2016-10-10 2019-10-31 Transgene Sa Immunotherapeutic product and mdsc modulator combination therapy
CA3044074A1 (en) 2016-11-16 2018-05-24 Immunomic Therapeutics, Inc. Nucleic acids for treatment of allergies
JP2020517271A (ja) 2017-04-22 2020-06-18 イミュノミック セラピューティックス， インコーポレイテッドＩｍｍｕｎｏｍｉｃ Ｔｈｅｒａｐｅｕｔｉｃｓ， Ｉｎｃ． 改良ｌａｍｐ構築物
JP7222915B2 (ja) 2017-05-02 2023-02-15 イミュノミック セラピューティックス， インコーポレイテッド 癌抗原を含む改善されたｌａｍｐ構築物
US11603527B2 (en) 2017-12-27 2023-03-14 Global Life Sciences Solutions Usa Llc Method and kit for viral vector isolation
US20210261647A1 (en) 2018-05-15 2021-08-26 Immunomic Therapeutics, Inc Lamp constructs comprising allergens
GB201820806D0 (en) 2018-12-20 2019-02-06 Ge Healthcare Bioprocess R&D Ab Large pore agarose
TW202043256A (zh) 2019-01-10 2020-12-01 美商健生生物科技公司 前列腺新抗原及其用途
CN114641306A (zh) 2019-10-18 2022-06-17 免疫治疗有限公司 包含癌抗原的改良lamp构建物
JOP20220116A1 (ar) 2019-11-18 2023-01-30 Janssen Biotech Inc اللقاحات المستندة إلى الطافر calr وjak2 واستخداماتها
TW202144389A (zh) 2020-02-14 2021-12-01 美商健生生物科技公司 在多發性骨髓瘤中表現之新抗原及其用途
TW202144388A (zh) 2020-02-14 2021-12-01 美商健生生物科技公司 在卵巢癌中表現之新抗原及其用途
EP4135757A1 (de) 2020-04-13 2023-02-22 Janssen Biotech, Inc. Psma- und steap1-impfstoffe und ihre verwendungen
WO2022009052A2 (en) 2020-07-06 2022-01-13 Janssen Biotech, Inc. Prostate neoantigens and their uses
EP4175721A1 (de) 2020-07-06 2023-05-10 Janssen Biotech, Inc. Prostata-neoantigene und ihre verwendungen
WO2022009051A1 (en) 2020-07-06 2022-01-13 Janssen Biotech, Inc. A method for determining responsiveness to prostate cancer treatment
WO2023201201A1 (en) 2022-04-10 2023-10-19 Immunomic Therapeutics, Inc. Bicistronic lamp constructs comprising immune response enhancing genes and methods of use thereof

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Publication number Priority date Publication date Assignee Title
IT1248075B (it) * 1991-06-18 1995-01-05 Sclavo Spa Processo per la purificazione del virus dell'epatite a (hav), virus cosi` purificato e composizioni vaccinali che lo contengono.
FR2696748B1 (fr) * 1992-10-14 1994-12-30 Pasteur Merieux Serums Vacc Procédé de préparation d'antigènes et de vaccins de l'hépatite A (HAV).
SK283703B6 (sk) 1993-10-25 2003-12-02 Canji, Inc. Rekombinantný adenovírusový vektor a jeho použitie
WO1997008298A1 (en) 1995-08-30 1997-03-06 Genzyme Corporation Chromatographic purification of adenovirus and aav
BR9710030A (pt) 1996-07-01 1999-08-10 Rhone Poulenc Rorer Sa Processo de produção de adenovírus recombinantes processo de purificação de adenovírus recombinantes a partir de um meio biológico preparação viral purificada composição farmacêutica e utilização de iodixanol-5,5'-[(2-Hidroxipropil-1,3-Propanottl)-Bis[N,N'-Bis(2,3-Didroxipropil-2,4,6-Triodo-1,3-Benzenocarboxamida]

Also Published As

Publication number Publication date
EP0948601A1 (de) 1999-10-13
ES2283032T3 (es) 2007-10-16
DE69737364D1 (de) 2007-03-29
JP2005318898A (ja) 2005-11-17
IL130198A (en) 2005-09-25
JP2001506126A (ja) 2001-05-15
JP2009022292A (ja) 2009-02-05
EP1679368B1 (de) 2010-08-11
ES2349046T3 (es) 2010-12-22
EP0948601B1 (de) 2007-02-14
DE69737364T2 (de) 2007-11-29
ATE477320T1 (de) 2010-08-15
IL130198A0 (en) 2000-06-01
CA2274876A1 (en) 1998-06-18
ATE353956T1 (de) 2007-03-15
AU5370598A (en) 1998-07-03
EP1679368A1 (de) 2006-07-12
WO1998026048A1 (en) 1998-06-18

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