JP2015533372A5 - - Google Patents
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- Publication number
- JP2015533372A5 JP2015533372A5 JP2015537303A JP2015537303A JP2015533372A5 JP 2015533372 A5 JP2015533372 A5 JP 2015533372A5 JP 2015537303 A JP2015537303 A JP 2015537303A JP 2015537303 A JP2015537303 A JP 2015537303A JP 2015533372 A5 JP2015533372 A5 JP 2015533372A5
- Authority
- JP
- Japan
- Prior art keywords
- body structural
- alpha body
- structural sequence
- polypeptide
- positively charged
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201261716783P | 2012-10-22 | 2012-10-22 | |
| EP12189485.1 | 2012-10-22 | ||
| US61/716,783 | 2012-10-22 | ||
| EP12189485 | 2012-10-22 | ||
| PCT/EP2013/072050 WO2014064092A1 (en) | 2012-10-22 | 2013-10-22 | Polypeptides capable of cellular internalization |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2015533372A JP2015533372A (ja) | 2015-11-24 |
| JP2015533372A5 true JP2015533372A5 (enExample) | 2016-12-08 |
Family
ID=47046473
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2015537303A Pending JP2015533372A (ja) | 2012-10-22 | 2013-10-22 | 細胞インターナリゼーション可能なポリペプチド |
Country Status (7)
| Country | Link |
|---|---|
| US (1) | US10023647B2 (enExample) |
| EP (1) | EP2909233B1 (enExample) |
| JP (1) | JP2015533372A (enExample) |
| AU (1) | AU2013336753B2 (enExample) |
| CA (1) | CA2888930C (enExample) |
| DK (1) | DK2909233T3 (enExample) |
| WO (1) | WO2014064092A1 (enExample) |
Families Citing this family (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2016506361A (ja) * | 2012-10-22 | 2016-03-03 | コンプリクス エン ヴェー | Ｉｌ−２３に特異的に結合するポリペプチド |
| EP3650465A1 (en) * | 2018-11-12 | 2020-05-13 | Navigo Proteins Gmbh | Novel populations of polypeptides having a triple-helical structure |
| EP4036117A1 (en) | 2021-01-27 | 2022-08-03 | Complix NV | Mcl-1 binding alphabodies and uses thereof |
| WO2023203127A1 (en) | 2022-04-20 | 2023-10-26 | Vib Vzw | Alphabody-based degrader molecules |
Family Cites Families (13)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| NZ551934A (en) | 2004-06-24 | 2009-09-25 | Inst Medical W & E Hall | Conjugates comprising a targeting moiety and a peptide that mimics the apoptosis-inducing BH3-only proteins |
| EP1998809B1 (en) | 2006-03-30 | 2014-06-25 | Drais Pharmaceuticals, Inc. | Camptothecin-cell penetrating peptide conjugates and pharmaceutical compositions containing the same |
| EP2161278B1 (en) | 2008-09-08 | 2012-05-23 | Complix N.V. | Single-chain coiled coil scaffold |
| CA2749558C (en) * | 2008-12-08 | 2019-01-15 | Complix Nv | Single-chain antiparallel coiled coil proteins |
| EP3549951A3 (en) | 2008-12-09 | 2019-11-20 | Dana Farber Cancer Institute, Inc. | Methods and compositions for specific modulation of mcl-1 |
| WO2010129023A2 (en) * | 2009-04-28 | 2010-11-11 | President And Fellows Of Harvard College | Supercharged proteins for cell penetration |
| GB2471693A (en) | 2009-07-08 | 2011-01-12 | Complix Nv | Parathyroid hormone related protein antagonists |
| GB2471692A (en) | 2009-07-08 | 2011-01-12 | Complix Nv | HIV gp41-binding single-chain coiled-coil peptide comprising heptad repeats |
| US20140294828A1 (en) | 2011-01-06 | 2014-10-02 | Complix Sa | Alphabodies specifically binding to viral proteins and methods for producing the same |
| AU2011354262B2 (en) * | 2011-01-06 | 2016-09-08 | Complix Nv | Alphabody libraries and methods for producing the same |
| DK2661447T3 (en) | 2011-01-06 | 2015-11-02 | Complix N V | Alphabodies that specifically bind to cytokines or growth factors and / or cytokine or growth factor receptors |
| US20130261049A1 (en) * | 2011-01-06 | 2013-10-03 | Complix Sa | Alphabodies specifically binding to class-i viral fusion proteins and methods for producing the same |
| BR112014016744A2 (en) * | 2012-01-06 | 2018-09-04 | Complix Nv | polypeptide, pharmaceutical composition and method for producing one or more polypeptides |
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2013
- 2013-10-22 DK DK13788700.6T patent/DK2909233T3/en active
- 2013-10-22 CA CA2888930A patent/CA2888930C/en active Active
- 2013-10-22 US US14/437,063 patent/US10023647B2/en active Active
- 2013-10-22 WO PCT/EP2013/072050 patent/WO2014064092A1/en not_active Ceased
- 2013-10-22 EP EP13788700.6A patent/EP2909233B1/en active Active
- 2013-10-22 JP JP2015537303A patent/JP2015533372A/ja active Pending
- 2013-10-22 AU AU2013336753A patent/AU2013336753B2/en not_active Ceased