JP2014513941A5 - - Google Patents
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- JP2014513941A5 JP2014513941A5 JP2014505502A JP2014505502A JP2014513941A5 JP 2014513941 A5 JP2014513941 A5 JP 2014513941A5 JP 2014505502 A JP2014505502 A JP 2014505502A JP 2014505502 A JP2014505502 A JP 2014505502A JP 2014513941 A5 JP2014513941 A5 JP 2014513941A5
- Authority
- JP
- Japan
- Prior art keywords
- seq
- fusion protein
- amino acid
- acid sequence
- positions
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201110132218A CN102219860B (zh) | 2011-05-20 | 2011-05-20 | FGFR-Fc融合蛋白及其用途 |
| PCT/CN2012/075706 WO2012159550A1 (zh) | 2011-05-20 | 2012-05-18 | FGFR-Fc融合蛋白及其用途 |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2016038502A Division JP6138304B2 (ja) | 2016-03-01 | 2016-03-01 | ＦＧＦＲ−Ｆｃ融合蛋白質およびその使用 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2014513941A JP2014513941A (ja) | 2014-06-19 |
| JP2014513941A5 true JP2014513941A5 (enExample) | 2014-10-23 |
Family
ID=44776585
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2014505502A Pending JP2014513941A (ja) | 2011-05-20 | 2012-05-18 | ＦＧＦＲ−Ｆｃ融合蛋白質およびその使用 |
Country Status (11)
| Country | Link |
|---|---|
| US (2) | US9273137B2 (enExample) |
| EP (2) | EP2711376B1 (enExample) |
| JP (1) | JP2014513941A (enExample) |
| KR (2) | KR101660336B1 (enExample) |
| CN (1) | CN102219860B (enExample) |
| AU (1) | AU2012261412B2 (enExample) |
| BR (1) | BR112013022285B1 (enExample) |
| CA (1) | CA2834584C (enExample) |
| DK (1) | DK3173102T3 (enExample) |
| RU (1) | RU2560573C2 (enExample) |
| WO (1) | WO2012159550A1 (enExample) |
Families Citing this family (12)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN102219860B (zh) * | 2011-05-20 | 2012-09-12 | 烟台荣昌生物工程有限公司 | FGFR-Fc融合蛋白及其用途 |
| AU2013295805B2 (en) * | 2012-07-24 | 2019-05-02 | The Trustees Of Columbia University In The City Of New York | Fusion proteins and methods thereof |
| EA201591324A1 (ru) | 2013-01-16 | 2016-01-29 | Инсерм (Энститю Насьональ Де Ля Сантэ Э Де Ля Решерш Медикаль) | Полипептид растворимого рецептора 3 фактора роста фибробластов (fgr3) для применения с целью предотвращения или лечения нарушений, связанных с замедлением роста скелета |
| US9957313B2 (en) | 2013-03-15 | 2018-05-01 | Remegen, Ltd. | FGFR-FC fusion proteins and the use thereof |
| WO2014190147A2 (en) * | 2013-05-23 | 2014-11-27 | Five Prime Therapeutics, Inc. | Methods of treating cancer |
| BR112016017137B1 (pt) * | 2014-02-07 | 2022-10-11 | Principia Biopharma, Inc | Composto e/ou sal farmaceuticamente aceitável do mesmo e composições farmacêuticas |
| CN105983093A (zh) * | 2015-02-11 | 2016-10-05 | 烟台荣昌生物工程有限公司 | 血管新生因子融合蛋白在制备用于治疗与血管新生相关的眼部疾病药物中的应用 |
| RU2751483C2 (ru) | 2016-07-07 | 2021-07-14 | Пфайзер Инк. | Полипептиды, являющиеся растворимыми рецепторами 3 фактора роста фибробластов (sfgfr3), и пути их применения |
| JP7247097B2 (ja) * | 2017-03-17 | 2023-03-28 | バクシム アクチェンゲゼルシャフト | がん免疫療法のための新規ｐｄ－ｌ１標的ｄｎａワクチン |
| CN111328336B (zh) | 2018-12-07 | 2024-01-30 | 荣昌生物制药(烟台)股份有限公司 | 一种双功能血管生成抑制剂及其用途 |
| CN116143941B (zh) * | 2022-09-08 | 2024-06-04 | 浙江省血液中心 | 一种KIR3DL1-IgG-Fc融合重组蛋白、应用及试剂盒 |
| CN118420715B (zh) * | 2023-03-23 | 2025-01-24 | 湖南中晟全肽生物科技股份有限公司 | 一种结合fgfr2受体的多肽及其用途 |
Family Cites Families (14)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| IL99120A0 (en) | 1991-08-07 | 1992-07-15 | Yeda Res & Dev | Multimers of the soluble forms of tnf receptors,their preparation and pharmaceutical compositions containing them |
| US6656728B1 (en) * | 1999-02-08 | 2003-12-02 | Chiron Corporation | Fibroblast growth factor receptor-immunoglobulin fusion |
| DE102005007665A1 (de) * | 2005-02-19 | 2006-08-31 | Degussa Ag | Folie auf Basis eines Polyamidblends |
| EP2083081A1 (en) * | 2005-07-22 | 2009-07-29 | Five Prime Therapeutics, Inc. | Compositions and methods of treating disease with FGFR fusion proteins |
| CA2655205A1 (en) * | 2006-06-12 | 2007-12-21 | Receptor Biologix Inc. | Pan-cell surface receptor- specific therapeutics |
| RU2341198C2 (ru) * | 2006-11-27 | 2008-12-20 | ФГУ Ростовский научно-исследовательский онкологический институт Росздрава | Способ оценки ангиогенных факторов при химиотерапии рака молочной железы |
| ES2366160T3 (es) * | 2006-11-28 | 2011-10-17 | Aventis Pharma S.A. | Fusiones de fc con receptor para fgf soluble modificadas con actividad biológica mejorada. |
| CL2007003411A1 (es) * | 2006-11-28 | 2008-07-04 | Centelion | Proteina fusion que consiste en una region fc de una inmunoglobulina con un fragmento o dominio soluble de un receptor para fgf; polinucleotido que la codifica y vector y celula que lo comprenden; composicion farmaceutica que comprende la proteina fu |
| WO2008133873A2 (en) * | 2007-04-25 | 2008-11-06 | Aveo Pharmaceuticals, Inc. | Fgf-binding fusion proteins |
| FR2933702A1 (fr) * | 2008-07-08 | 2010-01-15 | Sanofi Aventis | Antagonistes specifiques du recepteur fgf-r4 |
| RU2509774C2 (ru) * | 2008-08-04 | 2014-03-20 | Файв Прайм Терапьютикс, Инк. | Мутеины кислотной зоны внеклеточного домена рецептора фактора роста фибробластов |
| US8614183B2 (en) * | 2009-11-13 | 2013-12-24 | Five Prime Therapeutics, Inc. | Use of FGFR1 extra cellular domain proteins to treat cancers characterized by ligand-dependent activating mutations in FGFR2 |
| CN102219859B (zh) * | 2011-05-20 | 2012-09-12 | 烟台荣昌生物工程有限公司 | 拮抗血管新生诱导因子的融合蛋白及其用途 |
| CN102219860B (zh) * | 2011-05-20 | 2012-09-12 | 烟台荣昌生物工程有限公司 | FGFR-Fc融合蛋白及其用途 |
-
2011
- 2011-05-20 CN CN201110132218A patent/CN102219860B/zh active Active
-
2012
- 2012-05-18 BR BR112013022285-9A patent/BR112013022285B1/pt active IP Right Grant
- 2012-05-18 AU AU2012261412A patent/AU2012261412B2/en active Active
- 2012-05-18 EP EP12788998.8A patent/EP2711376B1/en active Active
- 2012-05-18 RU RU2013140184/10A patent/RU2560573C2/ru active
- 2012-05-18 EP EP16205128.8A patent/EP3173102B1/en active Active
- 2012-05-18 KR KR1020167001261A patent/KR101660336B1/ko active Active
- 2012-05-18 CA CA2834584A patent/CA2834584C/en active Active
- 2012-05-18 DK DK16205128.8T patent/DK3173102T3/da active
- 2012-05-18 KR KR1020137023245A patent/KR20130119978A/ko not_active Ceased
- 2012-05-18 JP JP2014505502A patent/JP2014513941A/ja active Pending
- 2012-05-18 WO PCT/CN2012/075706 patent/WO2012159550A1/zh not_active Ceased
-
2013
- 2013-03-15 US US13/842,345 patent/US9273137B2/en active Active
-
2016
- 2016-02-29 US US15/056,207 patent/US20160176945A1/en not_active Abandoned
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