JP2014513941A5 - - Google Patents
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- Publication number
- JP2014513941A5 JP2014513941A5 JP2014505502A JP2014505502A JP2014513941A5 JP 2014513941 A5 JP2014513941 A5 JP 2014513941A5 JP 2014505502 A JP2014505502 A JP 2014505502A JP 2014505502 A JP2014505502 A JP 2014505502A JP 2014513941 A5 JP2014513941 A5 JP 2014513941A5
- Authority
- JP
- Japan
- Prior art keywords
- seq
- fusion protein
- amino acid
- acid sequence
- positions
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201110132218A CN102219860B (zh) | 2011-05-20 | 2011-05-20 | FGFR-Fc融合蛋白及其用途 |
| PCT/CN2012/075706 WO2012159550A1 (zh) | 2011-05-20 | 2012-05-18 | FGFR-Fc融合蛋白及其用途 |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2016038502A Division JP6138304B2 (ja) | 2016-03-01 | 2016-03-01 | ＦＧＦＲ−Ｆｃ融合蛋白質およびその使用 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2014513941A JP2014513941A (ja) | 2014-06-19 |
| JP2014513941A5 true JP2014513941A5 (enExample) | 2014-10-23 |
Family
ID=44776585
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2014505502A Pending JP2014513941A (ja) | 2011-05-20 | 2012-05-18 | ＦＧＦＲ−Ｆｃ融合蛋白質およびその使用 |
Country Status (11)
| Country | Link |
|---|---|
| US (2) | US9273137B2 (enExample) |
| EP (2) | EP3173102B1 (enExample) |
| JP (1) | JP2014513941A (enExample) |
| KR (2) | KR101660336B1 (enExample) |
| CN (1) | CN102219860B (enExample) |
| AU (1) | AU2012261412B2 (enExample) |
| BR (1) | BR112013022285B1 (enExample) |
| CA (1) | CA2834584C (enExample) |
| DK (1) | DK3173102T3 (enExample) |
| RU (1) | RU2560573C2 (enExample) |
| WO (1) | WO2012159550A1 (enExample) |
Families Citing this family (12)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN102219860B (zh) * | 2011-05-20 | 2012-09-12 | 烟台荣昌生物工程有限公司 | FGFR-Fc融合蛋白及其用途 |
| CA2880013C (en) * | 2012-07-24 | 2022-11-29 | The Trustees Of Columbia University In The City Of New York | Fusion proteins and methods thereof |
| US20150344855A1 (en) * | 2013-01-16 | 2015-12-03 | INSERM (Institut National de la Santé et de la Recherche Médicale | A Soluble Fibroblast Growth Factor Receptor 3 (FGR3) Polypeptide For Use In The Prevention Or Treatment Of Skeletal Growth Retardation Disorders |
| US9957313B2 (en) | 2013-03-15 | 2018-05-01 | Remegen, Ltd. | FGFR-FC fusion proteins and the use thereof |
| WO2014190147A2 (en) * | 2013-05-23 | 2014-11-27 | Five Prime Therapeutics, Inc. | Methods of treating cancer |
| DK3102577T3 (en) * | 2014-02-07 | 2018-11-12 | Principia Biopharma Inc | QUINOLONDERIVATIVES AS FIBROBLAST GROWTH FACTOR RECEPTOR INHIBITORS |
| CN105983093A (zh) * | 2015-02-11 | 2016-10-05 | 烟台荣昌生物工程有限公司 | 血管新生因子融合蛋白在制备用于治疗与血管新生相关的眼部疾病药物中的应用 |
| KR102432192B1 (ko) | 2016-07-07 | 2022-08-12 | 화이자 인코포레이티드 | 가용성 섬유아세포 성장 인자 수용체 3(sfgfr3) 폴리펩티드 및 이의 용도 |
| SG11201908528UA (en) * | 2017-03-17 | 2019-10-30 | Vaximm Ag | Novel pd-l1 targeting dna vaccine for cancer immunotherapy |
| BR112021003275A2 (pt) | 2018-12-07 | 2021-06-22 | Remegen Co., Ltd. | inibidor de angiogênese bifuncional e uso do mesmo |
| CN116143941B (zh) * | 2022-09-08 | 2024-06-04 | 浙江省血液中心 | 一种KIR3DL1-IgG-Fc融合重组蛋白、应用及试剂盒 |
| CN116199744B (zh) * | 2023-03-23 | 2024-06-25 | 湖南中晟全肽生物科技股份有限公司 | 一种结合fgfr2受体的多肽及其用途 |
Family Cites Families (14)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| IL99120A0 (en) | 1991-08-07 | 1992-07-15 | Yeda Res & Dev | Multimers of the soluble forms of tnf receptors,their preparation and pharmaceutical compositions containing them |
| WO2000046380A2 (en) * | 1999-02-08 | 2000-08-10 | Chiron Corporation | Fibroblast growth factor receptor-immunoglobulin fusion |
| DE102005007665A1 (de) | 2005-02-19 | 2006-08-31 | Degussa Ag | Folie auf Basis eines Polyamidblends |
| NZ565511A (en) * | 2005-07-22 | 2011-03-31 | Five Prime Therapeutics Inc | Compositions and methods of treating disease with FGFR fusion proteins |
| AU2007257683A1 (en) | 2006-06-12 | 2007-12-21 | Symphogen A/S | Pan-cell surface receptor- specific therapeutics |
| RU2341198C2 (ru) * | 2006-11-27 | 2008-12-20 | ФГУ Ростовский научно-исследовательский онкологический институт Росздрава | Способ оценки ангиогенных факторов при химиотерапии рака молочной железы |
| PE20081250A1 (es) * | 2006-11-28 | 2008-10-07 | Centelion | FUSIONES Fc CON RECEPTOR PARA FGF SOLUBLE MODIFICADAS, CON ACTIVIDAD BIOLOGICA MEJORADA |
| ZA200903134B (en) * | 2006-11-28 | 2010-08-25 | Centelion | Modified soluble FGF receptor FC fusions with improved biological activity |
| WO2008133873A2 (en) * | 2007-04-25 | 2008-11-06 | Aveo Pharmaceuticals, Inc. | Fgf-binding fusion proteins |
| FR2933702A1 (fr) * | 2008-07-08 | 2010-01-15 | Sanofi Aventis | Antagonistes specifiques du recepteur fgf-r4 |
| CN102171343B (zh) * | 2008-08-04 | 2017-07-14 | 戊瑞治疗有限公司 | Fgfr细胞外结构域酸性区突变蛋白 |
| PT2498799T (pt) * | 2009-11-13 | 2016-11-04 | Five Prime Therapeutics Inc | Utilização de proteínas do domínio extracelular rfcf1 para tratar cancros caracterizados por mutações ativadoras dependentes de ligando em rfcf2 |
| CN102219860B (zh) * | 2011-05-20 | 2012-09-12 | 烟台荣昌生物工程有限公司 | FGFR-Fc融合蛋白及其用途 |
| CN102219859B (zh) * | 2011-05-20 | 2012-09-12 | 烟台荣昌生物工程有限公司 | 拮抗血管新生诱导因子的融合蛋白及其用途 |
-
2011
- 2011-05-20 CN CN201110132218A patent/CN102219860B/zh active Active
-
2012
- 2012-05-18 WO PCT/CN2012/075706 patent/WO2012159550A1/zh not_active Ceased
- 2012-05-18 RU RU2013140184/10A patent/RU2560573C2/ru active
- 2012-05-18 KR KR1020167001261A patent/KR101660336B1/ko active Active
- 2012-05-18 EP EP16205128.8A patent/EP3173102B1/en active Active
- 2012-05-18 AU AU2012261412A patent/AU2012261412B2/en active Active
- 2012-05-18 DK DK16205128.8T patent/DK3173102T3/da active
- 2012-05-18 JP JP2014505502A patent/JP2014513941A/ja active Pending
- 2012-05-18 EP EP12788998.8A patent/EP2711376B1/en active Active
- 2012-05-18 KR KR1020137023245A patent/KR20130119978A/ko not_active Ceased
- 2012-05-18 CA CA2834584A patent/CA2834584C/en active Active
- 2012-05-18 BR BR112013022285-9A patent/BR112013022285B1/pt active IP Right Grant
-
2013
- 2013-03-15 US US13/842,345 patent/US9273137B2/en active Active
-
2016
- 2016-02-29 US US15/056,207 patent/US20160176945A1/en not_active Abandoned
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