JP2023538422A5 - - Google Patents
Info
- Publication number
- JP2023538422A5 JP2023538422A5 JP2023512669A JP2023512669A JP2023538422A5 JP 2023538422 A5 JP2023538422 A5 JP 2023538422A5 JP 2023512669 A JP2023512669 A JP 2023512669A JP 2023512669 A JP2023512669 A JP 2023512669A JP 2023538422 A5 JP2023538422 A5 JP 2023538422A5
- Authority
- JP
- Japan
- Prior art keywords
- modified
- polypeptide
- polypeptide according
- sequence
- less
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US202063067658P | 2020-08-19 | 2020-08-19 | |
| US63/067,658 | 2020-08-19 | ||
| PCT/IB2021/000574 WO2022038417A2 (en) | 2020-08-19 | 2021-08-19 | Modified il-18 polypeptides and uses thereof |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2023538422A JP2023538422A (ja) | 2023-09-07 |
| JP2023538422A5 true JP2023538422A5 (enExample) | 2024-08-20 |
Family
ID=78032459
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2023512669A Pending JP2023538422A (ja) | 2020-08-19 | 2021-08-19 | 修飾ｉｌ－１８ポリペプチドおよびその使用 |
Country Status (9)
| Country | Link |
|---|---|
| US (1) | US20220056091A1 (enExample) |
| EP (1) | EP4200323A2 (enExample) |
| JP (1) | JP2023538422A (enExample) |
| KR (1) | KR20230052956A (enExample) |
| CN (1) | CN116368148A (enExample) |
| AU (1) | AU2021327861A1 (enExample) |
| CA (1) | CA3189327A1 (enExample) |
| IL (1) | IL300638A (enExample) |
| WO (1) | WO2022038417A2 (enExample) |
Families Citing this family (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20190070262A1 (en) | 2017-09-06 | 2019-03-07 | Yale University | Interleukin-18 variants and methods of use |
| AR123978A1 (es) | 2020-11-02 | 2023-02-01 | Simcha Il 18 Inc | Variantes de la interleucina-18 y métodos de uso |
| JP2025508823A (ja) | 2022-02-23 | 2025-04-10 | ブライト ピーク セラピューティクス エージー | 免疫抗原特異的ｉｌ－１８免疫サイトカイン及びその使用 |
| WO2024044780A1 (en) * | 2022-08-26 | 2024-02-29 | Sutro Biopharma, Inc. | Interleukin-18 variants and uses thereof |
| US20240182536A1 (en) * | 2022-11-11 | 2024-06-06 | Mural Oncology, Inc. | Interleukin 18 variants |
| WO2025041095A2 (en) * | 2023-08-23 | 2025-02-27 | Bright Peak Therapeutics Ag | Il-18 polypeptides modified with polymers |
| US12134635B1 (en) | 2023-12-29 | 2024-11-05 | Sonnet BioTherapeutics, Inc. | Interleukin 18 (IL-18) variants and fusion proteins comprising same |
| WO2025151273A1 (en) * | 2024-01-08 | 2025-07-17 | Adimab, Llc | Il-18 polypeptides and uses thereof |
| WO2025242835A1 (en) | 2024-05-22 | 2025-11-27 | Ose Immunotherapeutics | Molecules comprising masking linkers and uses thereof for the treatment of cancer |
| WO2026083296A1 (en) | 2024-10-16 | 2026-04-23 | Bright Peak Therapeutics Ag | Trispecific compositions comprising il-18, vegf binding domains, and pd-1 binding domains |
Family Cites Families (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DK1392830T3 (da) * | 2001-03-08 | 2006-05-08 | Ares Trading Sa | Interleukin-18 mutanter, deres fremstilling og anvendelse |
| TW200510454A (en) * | 2003-04-15 | 2005-03-16 | Smithkline Beecham Corp | Conjugates comprising human IL-18 and substitution mutants thereof |
| WO2014189370A1 (en) | 2013-05-24 | 2014-11-27 | Stichting Katholieke Universiteit | Substituted azadibenzocyclooctyne compounds and their use in metal-free click reactions |
| WO2015112016A1 (en) | 2014-01-24 | 2015-07-30 | Synaffix B.V. | Process for the cycloaddition of a halogenated 1,3-dipole compound with a (hetero)cycloalkyne |
| CN121021395A (zh) | 2016-06-28 | 2025-11-28 | 文塔纳医疗系统公司 | 点击化学用于ihc和ish测定中的信号扩增的应用 |
| US20190070262A1 (en) * | 2017-09-06 | 2019-03-07 | Yale University | Interleukin-18 variants and methods of use |
-
2021
- 2021-08-19 IL IL300638A patent/IL300638A/en unknown
- 2021-08-19 CN CN202180071568.0A patent/CN116368148A/zh active Pending
- 2021-08-19 WO PCT/IB2021/000574 patent/WO2022038417A2/en not_active Ceased
- 2021-08-19 JP JP2023512669A patent/JP2023538422A/ja active Pending
- 2021-08-19 KR KR1020237009427A patent/KR20230052956A/ko active Pending
- 2021-08-19 CA CA3189327A patent/CA3189327A1/en active Pending
- 2021-08-19 EP EP21783575.0A patent/EP4200323A2/en not_active Withdrawn
- 2021-08-19 US US17/406,847 patent/US20220056091A1/en active Pending
- 2021-08-19 AU AU2021327861A patent/AU2021327861A1/en active Pending
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| TW496870B (en) | Compositions methods for stimulating megakaryocyte growth and differentiation | |
| JP2014519852A5 (enExample) | ||
| JP2010534486A5 (enExample) | ||
| JP2023081303A5 (enExample) | ||
| JP2001514858A5 (enExample) | ||
| JP2023528207A5 (enExample) | ||
| RU2007139915A (ru) | Haemophilus influenzae типа в | |
| JP2019196370A5 (enExample) | ||
| JP2010518006A5 (enExample) | ||
| JP2008505133A5 (enExample) | ||
| CN101588820A (zh) | α-乳清蛋白组合物 | |
| JP2008525033A5 (enExample) | ||
| JP2008538183A5 (enExample) | ||
| JP2006506942A5 (enExample) | ||
| JP2023554379A5 (enExample) | ||
| JP2010516290A5 (enExample) | ||
| JP2014513941A5 (enExample) | ||
| JP2024513559A5 (enExample) | ||
| JPH06500114A (ja) | 組織再生促進及び癌治療用の生物活性ｅｇｆペプチド | |
| JP2010513327A5 (enExample) | ||
| JP2023529839A5 (enExample) | ||
| JP2024535925A5 (enExample) | ||
| JP2024525213A5 (enExample) | ||
| CN112010959A (zh) | αO-芋螺毒素肽GeXIVA新突变体、其药物组合物及用途 | |
| JP2009540842A5 (enExample) |