JP2015521588A5 - - Google Patents
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- Publication number
- JP2015521588A5 JP2015521588A5 JP2015516240A JP2015516240A JP2015521588A5 JP 2015521588 A5 JP2015521588 A5 JP 2015521588A5 JP 2015516240 A JP2015516240 A JP 2015516240A JP 2015516240 A JP2015516240 A JP 2015516240A JP 2015521588 A5 JP2015521588 A5 JP 2015521588A5
- Authority
- JP
- Japan
- Prior art keywords
- polypeptide
- amino acid
- seq
- fniii
- substitution
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201261656671P | 2012-06-07 | 2012-06-07 | |
| US61/656,671 | 2012-06-07 | ||
| PCT/US2013/044699 WO2013185027A2 (en) | 2012-06-07 | 2013-06-07 | Modified fibronectin fragments or variants and uses thereof |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2015521588A JP2015521588A (ja) | 2015-07-30 |
| JP2015521588A5 true JP2015521588A5 (enExample) | 2016-07-28 |
| JP6297543B2 JP6297543B2 (ja) | 2018-03-20 |
Family
ID=49712865
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2015516240A Active JP6297543B2 (ja) | 2012-06-07 | 2013-06-07 | 修飾フィブロネクチンフラグメント又はバリアント及びその使用 |
Country Status (14)
| Country | Link |
|---|---|
| US (1) | US9969791B2 (enExample) |
| EP (1) | EP2859113A4 (enExample) |
| JP (1) | JP6297543B2 (enExample) |
| KR (1) | KR20150041619A (enExample) |
| CN (1) | CN104968796A (enExample) |
| AU (1) | AU2013271445B2 (enExample) |
| BR (1) | BR112014030716A2 (enExample) |
| CA (1) | CA2876135A1 (enExample) |
| IL (1) | IL236098A0 (enExample) |
| IN (1) | IN2015MN00027A (enExample) |
| MX (1) | MX2014015028A (enExample) |
| SG (1) | SG11201408163VA (enExample) |
| TW (1) | TWI580692B (enExample) |
| WO (1) | WO2013185027A2 (enExample) |
Families Citing this family (14)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AU2013271445B2 (en) * | 2012-06-07 | 2016-12-15 | National Cheng Kung University | Modified fibronectin fragments or variants and uses thereof |
| WO2015103643A2 (en) * | 2014-01-06 | 2015-07-09 | The General Hospital Corporation | Integrin antagonists |
| KR20180022873A (ko) * | 2015-06-26 | 2018-03-06 | 스파이버 테크놀러지스 에이비 | 고리형 rgd 세포-결합 모티프 및 이의 용도 |
| JP7174627B2 (ja) | 2015-10-23 | 2022-11-17 | ウニフェルシタイト・トゥヴェンテ | インテグリン結合ペプチド及びその使用 |
| WO2019165017A1 (en) * | 2018-02-23 | 2019-08-29 | The University Of Chicago | Methods and composition involving thermophilic fibronectin type iii (fn3) monobodies |
| AU2019318538B2 (en) | 2018-08-08 | 2025-02-06 | The General Hospital Corporation | Polypeptide integrin antagonists |
| CN111285932B (zh) * | 2018-12-10 | 2023-07-11 | 武汉禾元生物科技股份有限公司 | 一种从基因工程水稻种子中分离纯化重组人纤维连接蛋白的方法 |
| CN113092772A (zh) * | 2019-12-23 | 2021-07-09 | 首都医科大学附属北京世纪坛医院 | 尿液黏连蛋白亚组sa-2及其多肽片段在过敏性疾病中的应用 |
| CN114686991A (zh) * | 2021-03-02 | 2022-07-01 | 北京创智智能健康技术研究院有限公司 | 一种具有类似纤维粘连蛋白结构域的拟抗体筛选库、其构建方法及应用 |
| CN112941081B (zh) * | 2021-04-16 | 2023-04-21 | 广州启点生物科技有限公司 | 一种纤连蛋白突变体及其制备方法与应用 |
| US11723955B1 (en) | 2022-05-13 | 2023-08-15 | Allgenesis Biotherapeutics Inc. | VEGFR fusion protein pharmaceutical composition |
| TWI836609B (zh) * | 2022-09-16 | 2024-03-21 | 國立成功大學 | 纖維黏蛋白第iii型結構域衍生的蛋白質及其應用 |
| CN116574173A (zh) * | 2023-06-25 | 2023-08-11 | 浙江诸暨聚源生物技术有限公司 | 蛋白稳定性增强的重组人源纤连蛋白突变体及其表达菌株 |
| CN117298257B (zh) * | 2023-07-14 | 2024-07-30 | 杭州恩和生物科技有限公司 | 人纤连蛋白或其功能片段的用途、筛选方法和试剂盒 |
Family Cites Families (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4554101A (en) | 1981-01-09 | 1985-11-19 | New York Blood Center, Inc. | Identification and preparation of epitopes on antigens and allergens on the basis of hydrophilicity |
| US5753230A (en) * | 1994-03-18 | 1998-05-19 | The Scripps Research Institute | Methods and compositions useful for inhibition of angiogenesis |
| US20050118661A1 (en) * | 2002-01-21 | 2005-06-02 | Helen Mardon | Fibronectin variants and screening methods |
| BRPI0906739A2 (pt) * | 2008-01-18 | 2015-08-04 | Burnham Inst Medical Research | Métodos e composições relacionadas para internalizar peptídeos de rgd |
| US9072706B2 (en) * | 2010-12-14 | 2015-07-07 | University Of Rochester | Chimeric fibronectin matrix mimetics and uses therof |
| AU2013271445B2 (en) * | 2012-06-07 | 2016-12-15 | National Cheng Kung University | Modified fibronectin fragments or variants and uses thereof |
-
2013
- 2013-06-07 AU AU2013271445A patent/AU2013271445B2/en not_active Ceased
- 2013-06-07 SG SG11201408163VA patent/SG11201408163VA/en unknown
- 2013-06-07 US US14/406,215 patent/US9969791B2/en active Active
- 2013-06-07 MX MX2014015028A patent/MX2014015028A/es unknown
- 2013-06-07 TW TW102120488A patent/TWI580692B/zh active
- 2013-06-07 WO PCT/US2013/044699 patent/WO2013185027A2/en not_active Ceased
- 2013-06-07 CA CA2876135A patent/CA2876135A1/en not_active Abandoned
- 2013-06-07 JP JP2015516240A patent/JP6297543B2/ja active Active
- 2013-06-07 BR BR112014030716A patent/BR112014030716A2/pt not_active Application Discontinuation
- 2013-06-07 KR KR20157000345A patent/KR20150041619A/ko not_active Withdrawn
- 2013-06-07 CN CN201380030284.2A patent/CN104968796A/zh active Pending
- 2013-06-07 IN IN27MUN2015 patent/IN2015MN00027A/en unknown
- 2013-06-07 EP EP13800217.5A patent/EP2859113A4/en not_active Withdrawn
-
2014
- 2014-12-07 IL IL236098A patent/IL236098A0/en unknown
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