JP2015531241A5 - - Google Patents

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Publication number
JP2015531241A5
JP2015531241A5 JP2015536869A JP2015536869A JP2015531241A5 JP 2015531241 A5 JP2015531241 A5 JP 2015531241A5 JP 2015536869 A JP2015536869 A JP 2015536869A JP 2015536869 A JP2015536869 A JP 2015536869A JP 2015531241 A5 JP2015531241 A5 JP 2015531241A5
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JP
Japan
Prior art keywords
starting
bioreactor
perfusion
cell
cells
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JP2015536869A
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English (en)
Japanese (ja)
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JP2015531241A (ja
JP6393267B2 (ja
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Priority claimed from PCT/US2013/064159 external-priority patent/WO2014059035A1/en
Publication of JP2015531241A publication Critical patent/JP2015531241A/ja
Publication of JP2015531241A5 publication Critical patent/JP2015531241A5/ja
Application granted granted Critical
Publication of JP6393267B2 publication Critical patent/JP6393267B2/ja
Expired - Fee Related legal-status Critical Current
Anticipated expiration legal-status Critical

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JP2015536869A 2012-10-10 2013-10-09 かん流細胞培養システムを最適化するための方法およびシステム Expired - Fee Related JP6393267B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201261712190P 2012-10-10 2012-10-10
US61/712,190 2012-10-10
PCT/US2013/064159 WO2014059035A1 (en) 2012-10-10 2013-10-09 Methods and systems for optimizing perfusion cell culture system

Publications (3)

Publication Number Publication Date
JP2015531241A JP2015531241A (ja) 2015-11-02
JP2015531241A5 true JP2015531241A5 (https=) 2017-12-14
JP6393267B2 JP6393267B2 (ja) 2018-09-19

Family

ID=49448331

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2015536869A Expired - Fee Related JP6393267B2 (ja) 2012-10-10 2013-10-09 かん流細胞培養システムを最適化するための方法およびシステム

Country Status (15)

Country Link
US (2) US20140099711A1 (https=)
EP (1) EP2906677A1 (https=)
JP (1) JP6393267B2 (https=)
KR (1) KR20150063541A (https=)
CN (1) CN104822821A (https=)
AR (1) AR092967A1 (https=)
AU (1) AU2013329318A1 (https=)
CA (1) CA2887581A1 (https=)
HK (1) HK1213285A1 (https=)
IL (1) IL238179A0 (https=)
MX (1) MX2015004516A (https=)
RU (1) RU2015117547A (https=)
SG (2) SG11201502741WA (https=)
TW (1) TW201418455A (https=)
WO (1) WO2014059035A1 (https=)

Families Citing this family (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US9944894B2 (en) 2015-01-16 2018-04-17 General Electric Company Pluripotent stem cell expansion and passage using a rocking platform bioreactor
CN105385731B (zh) * 2015-12-25 2018-10-30 上海莱士血液制品股份有限公司 一种表达重组八因子的灌注培养方法
ITUB20160272A1 (it) * 2016-01-22 2017-07-22 Univ Degli Studi Di Palermo Bioreattore a perfusione autosufficiente monouso per crescite cellulari 3D
CN108779424A (zh) * 2016-03-21 2018-11-09 通用电气公司 使用搅拌槽生物反应器的多能干细胞扩增和传代
US11609120B2 (en) 2017-10-06 2023-03-21 Lonza Ltd Automated control of cell culture using Raman spectroscopy
EP4039786A1 (en) 2017-10-16 2022-08-10 Regeneron Pharmaceuticals, Inc. Perfusion bioreactor and related methods of use
WO2019226618A1 (en) * 2018-05-22 2019-11-28 Nantkwest, Inc. Methods and systems for cell bed formation during bioprocessing
US20210214702A1 (en) * 2018-06-01 2021-07-15 Gennova Biopharmaceuticals Limited Process for production of recombinant tnk-tpa by packed-bed perfusion system
EP3875595A4 (en) * 2018-11-02 2022-07-13 Kyowa Kirin Co., Ltd. Liquid medium preparation method
GB201903813D0 (en) * 2019-03-20 2019-05-01 Cn Bio Innovations Ltd Dual circulation microphysiological system
US12325848B2 (en) 2019-05-15 2025-06-10 Life Technologies Corporation Cell settler apparatus systems and methods for perfusion processes
US12460170B2 (en) 2019-11-07 2025-11-04 Merck Patent Gmbh Methods and systems for performing perfusion cell culture
WO2021097281A1 (en) 2019-11-15 2021-05-20 Lonza Ltd Process and system for producing an inoculum
WO2021110870A1 (en) 2019-12-05 2021-06-10 Acib Gmbh Method for producing a fermentation product
WO2021123248A1 (en) * 2019-12-19 2021-06-24 Universität Für Bodenkultur Wien Continuous reconstitution of process materials from solids

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6338964B1 (en) 1999-05-07 2002-01-15 Bayer Corporation Process and medium for mammalian cell culture under low dissolved carbon dioxide concentration
US20040185534A1 (en) * 2000-10-02 2004-09-23 Knudsen Ida Molgaard Industrial-scale serum-free production of recombinant proteins in mammalian cells
EP1689878A4 (en) * 2003-11-03 2007-02-14 Centocor Inc METHOD FOR MAINTAINING LOW SHEAR IN A BIOTECHNOLOGICAL SYSTEM
WO2007071072A1 (en) * 2005-12-22 2007-06-28 Corporation De L'ecole Polytechnique De Montreal High-rate perfusion bioreactor
US20100167396A1 (en) * 2006-04-21 2010-07-01 Bayer Healthcare Llc Application of Anti-Apoptotic Gene Expression in Mammalian Cells for Perfusion Culture
ES2657055T3 (es) * 2007-08-09 2018-03-01 Wyeth Llc Uso de perfusión para mejorar la producción de un cultivo de células alimentado por lotes en biorreactores
US20090325287A1 (en) * 2008-06-13 2009-12-31 Haimanti Dorai Methods for Obtaining High Viable Cell Density in Mammalian Cell Culture
US9550969B2 (en) * 2011-03-18 2017-01-24 Ge Healthcare Bio-Sciences Ab Flexible bag for cultivation of cells

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