HK1213285A1 - 用於優化灌流細胞培養系統的方法和系統 - Google Patents
用於優化灌流細胞培養系統的方法和系統Info
- Publication number
- HK1213285A1 HK1213285A1 HK16101154.2A HK16101154A HK1213285A1 HK 1213285 A1 HK1213285 A1 HK 1213285A1 HK 16101154 A HK16101154 A HK 16101154A HK 1213285 A1 HK1213285 A1 HK 1213285A1
- Authority
- HK
- Hong Kong
- Prior art keywords
- systems
- methods
- cell culture
- culture system
- perfusion cell
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
- C12M29/00—Means for introduction, extraction or recirculation of materials, e.g. pumps
- C12M29/18—External loop; Means for reintroduction of fermented biomass or liquid percolate
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/745—Blood coagulation or fibrinolysis factors
- C07K14/755—Factors VIII, e.g. factor VIII C (AHF), factor VIII Ag (VWF)
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
- C12M21/00—Bioreactors or fermenters specially adapted for specific uses
- C12M21/14—Bioreactors or fermenters specially adapted for specific uses for producing enzymes
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
- C12M29/00—Means for introduction, extraction or recirculation of materials, e.g. pumps
- C12M29/02—Percolation
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
- C12M29/00—Means for introduction, extraction or recirculation of materials, e.g. pumps
- C12M29/10—Perfusion
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
- C12M41/00—Means for regulation, monitoring, measurement or control, e.g. flow regulation
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
- C12M41/00—Means for regulation, monitoring, measurement or control, e.g. flow regulation
- C12M41/44—Means for regulation, monitoring, measurement or control, e.g. flow regulation of volume or liquid level
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
- C12M47/00—Means for after-treatment of the produced biomass or of the fermentation or metabolic products, e.g. storage of biomass
- C12M47/02—Separating microorganisms from the culture medium; Concentration of biomass
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
- C12M47/00—Means for after-treatment of the produced biomass or of the fermentation or metabolic products, e.g. storage of biomass
- C12M47/10—Separation or concentration of fermentation products
Landscapes
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Zoology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Wood Science & Technology (AREA)
- Biotechnology (AREA)
- Genetics & Genomics (AREA)
- General Health & Medical Sciences (AREA)
- Biochemistry (AREA)
- Biomedical Technology (AREA)
- Sustainable Development (AREA)
- General Engineering & Computer Science (AREA)
- Microbiology (AREA)
- Analytical Chemistry (AREA)
- Molecular Biology (AREA)
- Medicinal Chemistry (AREA)
- Toxicology (AREA)
- Gastroenterology & Hepatology (AREA)
- Biophysics (AREA)
- Hematology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Apparatus Associated With Microorganisms And Enzymes (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201261712190P | 2012-10-10 | 2012-10-10 | |
| PCT/US2013/064159 WO2014059035A1 (en) | 2012-10-10 | 2013-10-09 | Methods and systems for optimizing perfusion cell culture system |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| HK1213285A1 true HK1213285A1 (zh) | 2016-06-30 |
Family
ID=49448331
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| HK16101154.2A HK1213285A1 (zh) | 2012-10-10 | 2016-02-02 | 用於優化灌流細胞培養系統的方法和系統 |
Country Status (15)
| Country | Link |
|---|---|
| US (2) | US20150299638A1 (zh) |
| EP (1) | EP2906677A1 (zh) |
| JP (1) | JP6393267B2 (zh) |
| KR (1) | KR20150063541A (zh) |
| CN (1) | CN104822821A (zh) |
| AR (1) | AR092967A1 (zh) |
| AU (1) | AU2013329318A1 (zh) |
| CA (1) | CA2887581A1 (zh) |
| HK (1) | HK1213285A1 (zh) |
| IL (1) | IL238179A0 (zh) |
| MX (1) | MX2015004516A (zh) |
| RU (1) | RU2015117547A (zh) |
| SG (2) | SG10201705806YA (zh) |
| TW (1) | TW201418455A (zh) |
| WO (1) | WO2014059035A1 (zh) |
Families Citing this family (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US9944894B2 (en) | 2015-01-16 | 2018-04-17 | General Electric Company | Pluripotent stem cell expansion and passage using a rocking platform bioreactor |
| CN105385731B (zh) * | 2015-12-25 | 2018-10-30 | 上海莱士血液制品股份有限公司 | 一种表达重组八因子的灌注培养方法 |
| ITUB20160272A1 (it) * | 2016-01-22 | 2017-07-22 | Univ Degli Studi Di Palermo | Bioreattore a perfusione autosufficiente monouso per crescite cellulari 3D |
| JP6943449B2 (ja) * | 2016-03-21 | 2021-09-29 | グローバル・ライフ・サイエンシズ・ソリューションズ・ユーエスエー・エルエルシー | 撹拌タンクバイオリアクタを用いた多能性幹細胞の増殖および継代 |
| KR20200068697A (ko) | 2017-10-06 | 2020-06-15 | 론자 리미티드 | 라만 분광법을 사용하는 세포 배양의 자동 제어 |
| CA3075679A1 (en) | 2017-10-16 | 2019-04-25 | Regeneron Pharmaceuticals, Inc. | Perfusion bioreactor and related methods of use |
| EP3875595A4 (en) * | 2018-11-02 | 2022-07-13 | Kyowa Kirin Co., Ltd. | METHOD FOR PREPARING LIQUID CULTURE MEDIUM |
| GB201903813D0 (en) * | 2019-03-20 | 2019-05-01 | Cn Bio Innovations Ltd | Dual circulation microphysiological system |
| WO2020232183A1 (en) * | 2019-05-15 | 2020-11-19 | Life Technologies Corporation | Cell settler apparatus systems and methods for perfusion processes |
| WO2021110870A1 (en) | 2019-12-05 | 2021-06-10 | Acib Gmbh | Method for producing a fermentation product |
Family Cites Families (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6338964B1 (en) | 1999-05-07 | 2002-01-15 | Bayer Corporation | Process and medium for mammalian cell culture under low dissolved carbon dioxide concentration |
| US20040185534A1 (en) * | 2000-10-02 | 2004-09-23 | Knudsen Ida Molgaard | Industrial-scale serum-free production of recombinant proteins in mammalian cells |
| EP1689878A4 (en) * | 2003-11-03 | 2007-02-14 | Centocor Inc | METHOD FOR MAINTAINING LOW SHEAR IN A BIOTECHNOLOGICAL SYSTEM |
| WO2007071072A1 (en) * | 2005-12-22 | 2007-06-28 | Corporation De L'ecole Polytechnique De Montreal | High-rate perfusion bioreactor |
| US20100167396A1 (en) * | 2006-04-21 | 2010-07-01 | Bayer Healthcare Llc | Application of Anti-Apoptotic Gene Expression in Mammalian Cells for Perfusion Culture |
| EP2188371B1 (en) * | 2007-08-09 | 2017-12-20 | Wyeth LLC | Use of perfusion to enhance production of fed-batch cell culture in bioreactors |
| AU2009257336B2 (en) * | 2008-06-13 | 2016-01-28 | Janssen Biotech, Inc. | Methods for obtaining high viable cell density in mammalian cell culture |
| WO2012128703A1 (en) * | 2011-03-18 | 2012-09-27 | Ge Healthcare Bio-Sciences Ab | Flexible bag for cultivation of cells |
-
2013
- 2013-10-09 SG SG10201705806YA patent/SG10201705806YA/en unknown
- 2013-10-09 AU AU2013329318A patent/AU2013329318A1/en not_active Abandoned
- 2013-10-09 US US14/434,913 patent/US20150299638A1/en not_active Abandoned
- 2013-10-09 EP EP13780035.5A patent/EP2906677A1/en not_active Withdrawn
- 2013-10-09 US US14/049,676 patent/US20140099711A1/en not_active Abandoned
- 2013-10-09 WO PCT/US2013/064159 patent/WO2014059035A1/en active Application Filing
- 2013-10-09 CA CA2887581A patent/CA2887581A1/en not_active Abandoned
- 2013-10-09 JP JP2015536869A patent/JP6393267B2/ja not_active Expired - Fee Related
- 2013-10-09 KR KR1020157011445A patent/KR20150063541A/ko not_active Application Discontinuation
- 2013-10-09 TW TW102136546A patent/TW201418455A/zh unknown
- 2013-10-09 SG SG11201502741WA patent/SG11201502741WA/en unknown
- 2013-10-09 MX MX2015004516A patent/MX2015004516A/es unknown
- 2013-10-09 RU RU2015117547A patent/RU2015117547A/ru not_active Application Discontinuation
- 2013-10-09 CN CN201380064458.7A patent/CN104822821A/zh active Pending
- 2013-10-10 AR ARP130103674A patent/AR092967A1/es unknown
-
2015
- 2015-04-12 IL IL238179A patent/IL238179A0/en unknown
-
2016
- 2016-02-02 HK HK16101154.2A patent/HK1213285A1/zh unknown
Also Published As
| Publication number | Publication date |
|---|---|
| SG10201705806YA (en) | 2017-08-30 |
| MX2015004516A (es) | 2015-10-14 |
| AU2013329318A1 (en) | 2015-05-14 |
| JP6393267B2 (ja) | 2018-09-19 |
| SG11201502741WA (en) | 2015-05-28 |
| US20150299638A1 (en) | 2015-10-22 |
| CN104822821A (zh) | 2015-08-05 |
| AR092967A1 (es) | 2015-05-06 |
| IL238179A0 (en) | 2015-05-31 |
| WO2014059035A1 (en) | 2014-04-17 |
| JP2015531241A (ja) | 2015-11-02 |
| EP2906677A1 (en) | 2015-08-19 |
| CA2887581A1 (en) | 2014-04-17 |
| US20140099711A1 (en) | 2014-04-10 |
| RU2015117547A (ru) | 2016-12-10 |
| TW201418455A (zh) | 2014-05-16 |
| KR20150063541A (ko) | 2015-06-09 |
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