JP2015530404A5 - - Google Patents
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- JP2015530404A5 JP2015530404A5 JP2015532965A JP2015532965A JP2015530404A5 JP 2015530404 A5 JP2015530404 A5 JP 2015530404A5 JP 2015532965 A JP2015532965 A JP 2015532965A JP 2015532965 A JP2015532965 A JP 2015532965A JP 2015530404 A5 JP2015530404 A5 JP 2015530404A5
- Authority
- JP
- Japan
- Prior art keywords
- peptide
- active ingredient
- conjugate
- composition
- seq
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
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- 108090000765 processed proteins & peptides Proteins 0.000 claims 21
- 239000004480 active ingredient Substances 0.000 claims 13
- 239000002872 contrast media Substances 0.000 claims 11
- 239000000203 mixture Substances 0.000 claims 9
- 210000004027 cell Anatomy 0.000 claims 5
- 239000012634 fragment Substances 0.000 claims 4
- 108010043121 Green Fluorescent Proteins Proteins 0.000 claims 2
- 102000004144 Green Fluorescent Proteins Human genes 0.000 claims 2
- XEEYBQQBJWHFJM-UHFFFAOYSA-N Iron Chemical compound [Fe] XEEYBQQBJWHFJM-UHFFFAOYSA-N 0.000 claims 2
- 150000001413 amino acids Chemical class 0.000 claims 2
- 239000002537 cosmetic Substances 0.000 claims 2
- 239000005090 green fluorescent protein Substances 0.000 claims 2
- 235000013402 health food Nutrition 0.000 claims 2
- 102000040430 polynucleotide Human genes 0.000 claims 2
- 108091033319 polynucleotide Proteins 0.000 claims 2
- 239000002157 polynucleotide Substances 0.000 claims 2
- 108090000623 proteins and genes Proteins 0.000 claims 2
- 102000004169 proteins and genes Human genes 0.000 claims 2
- 239000000126 substance Substances 0.000 claims 2
- 102000020313 Cell-Penetrating Peptides Human genes 0.000 claims 1
- 108010051109 Cell-Penetrating Peptides Proteins 0.000 claims 1
- 102000004190 Enzymes Human genes 0.000 claims 1
- 108090000790 Enzymes Proteins 0.000 claims 1
- 229930186217 Glycolipid Natural products 0.000 claims 1
- 102000008394 Immunoglobulin Fragments Human genes 0.000 claims 1
- 108010021625 Immunoglobulin Fragments Proteins 0.000 claims 1
- 125000003275 alpha amino acid group Chemical group 0.000 claims 1
- 201000010099 disease Diseases 0.000 claims 1
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 claims 1
- 239000003814 drug Substances 0.000 claims 1
- 229940079593 drug Drugs 0.000 claims 1
- MHMNJMPURVTYEJ-UHFFFAOYSA-N fluorescein-5-isothiocyanate Chemical compound O1C(=O)C2=CC(N=C=S)=CC=C2C21C1=CC=C(O)C=C1OC1=CC(O)=CC=C21 MHMNJMPURVTYEJ-UHFFFAOYSA-N 0.000 claims 1
- 238000003384 imaging method Methods 0.000 claims 1
- 229910052500 inorganic mineral Inorganic materials 0.000 claims 1
- 229910052742 iron Inorganic materials 0.000 claims 1
- 239000003446 ligand Substances 0.000 claims 1
- 150000002632 lipids Chemical class 0.000 claims 1
- 230000001404 mediated effect Effects 0.000 claims 1
- 239000011707 mineral Substances 0.000 claims 1
- 239000002105 nanoparticle Substances 0.000 claims 1
- 102000039446 nucleic acids Human genes 0.000 claims 1
- 108020004707 nucleic acids Proteins 0.000 claims 1
- 150000007523 nucleic acids Chemical class 0.000 claims 1
- 230000005298 paramagnetic effect Effects 0.000 claims 1
- 230000035699 permeability Effects 0.000 claims 1
- 239000008194 pharmaceutical composition Substances 0.000 claims 1
- 238000002360 preparation method Methods 0.000 claims 1
- 230000002265 prevention Effects 0.000 claims 1
- 102000004196 processed proteins & peptides Human genes 0.000 claims 1
- 210000000130 stem cell Anatomy 0.000 claims 1
- 235000000346 sugar Nutrition 0.000 claims 1
- 150000008163 sugars Chemical class 0.000 claims 1
- 230000001225 therapeutic effect Effects 0.000 claims 1
Applications Claiming Priority (9)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| KR20120104144 | 2012-09-19 | ||
| KR10-2012-0104144 | 2012-09-19 | ||
| KR10-2012-0109216 | 2012-09-28 | ||
| KR20120109216 | 2012-09-28 | ||
| KR20130017046 | 2013-02-18 | ||
| KR10-2013-0017169 | 2013-02-18 | ||
| KR20130017169 | 2013-02-18 | ||
| KR10-2013-0017046 | 2013-02-18 | ||
| PCT/KR2013/008445 WO2014046481A1 (ko) | 2012-09-19 | 2013-09-17 | 세포 투과성 펩티드, 그를 포함한 컨쥬게이트 및 그를 포함한 조성물 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2015530404A JP2015530404A (ja) | 2015-10-15 |
| JP2015530404A5 true JP2015530404A5 (enExample) | 2016-11-10 |
| JP6510410B2 JP6510410B2 (ja) | 2019-05-08 |
Family
ID=50341702
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2015532965A Active JP6510410B2 (ja) | 2012-09-19 | 2013-09-17 | 細胞透過性ペプチド、それを含んだコンジュゲート、及びそれを含んだ組成物 |
Country Status (8)
| Country | Link |
|---|---|
| US (1) | US9631184B2 (enExample) |
| EP (1) | EP2899199B1 (enExample) |
| JP (1) | JP6510410B2 (enExample) |
| KR (1) | KR102201430B1 (enExample) |
| CN (3) | CN110064056B (enExample) |
| ES (1) | ES2743919T3 (enExample) |
| TW (1) | TWI598441B (enExample) |
| WO (1) | WO2014046481A1 (enExample) |
Families Citing this family (27)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP6262721B2 (ja) | 2012-05-11 | 2018-01-17 | ジェムバックス アンド カエル カンパニー，リミティド | 敗血症の予防用または治療用の組成物 |
| CN116694597A (zh) | 2012-05-11 | 2023-09-05 | 珍白斯凯尔有限公司 | 具有抗炎活性的肽及其在制备抗炎组合物中的应用 |
| KR101799904B1 (ko) | 2012-07-11 | 2017-11-22 | 주식회사 젬백스앤카엘 | 세포 투과성 펩티드, 그를 포함한 컨쥬게이트 및 그를 포함한 조성물 |
| US20150125438A1 (en) | 2012-07-20 | 2015-05-07 | Sang Jae Kim | Anti-Inflammatory Peptides and Composition Comprising the Same |
| ES2758451T3 (es) | 2012-09-19 | 2020-05-05 | Gemvax & Kael Co Ltd | Péptido de penetración celular, conjugado que comprende el mismo y composición que comprende el conjugado |
| EP3736282B1 (en) | 2012-09-19 | 2023-06-21 | Gemvax & Kael Co., Ltd. | Cell penetrating peptide, conjugate comprising same, and composition comprising conjugate |
| WO2014171792A1 (ko) | 2013-04-19 | 2014-10-23 | 주식회사 카엘젬백스 | 허혈성 손상 치료 및 예방용 조성물 |
| US10383926B2 (en) | 2013-06-07 | 2019-08-20 | Gemvax & Kael Co., Ltd. | Biological markers useful in cancer immunotherapy |
| ES2808076T3 (es) | 2013-06-21 | 2021-02-25 | Gemvax & Kael Co Ltd | Regulador de la secreción hormonal, composición que lo contiene y procedimiento para controlar la secreción hormonal mediante su uso |
| WO2015005723A1 (ko) * | 2013-07-12 | 2015-01-15 | 주식회사 카엘젬백스 | 세포 투과성 펩티드 및 이를 포함하는 컨쥬게이트 |
| CA2926183C (en) | 2013-10-23 | 2018-07-03 | Gemvax & Kael Co., Ltd. | Composition for treating and preventing benign prostatic hyperplasia |
| EP3072519B1 (en) | 2013-11-22 | 2020-08-19 | Gemvax & Kael Co., Ltd. | Peptide having angiogenesis inhibitory activity and composition containing same |
| EP3085380B1 (en) | 2013-12-17 | 2020-06-17 | Gemvax & Kael Co., Ltd. | Composition for treating prostate cancer |
| KR102373603B1 (ko) | 2014-04-11 | 2022-03-14 | 주식회사 젬백스앤카엘 | 섬유증 억제 활성을 가지는 펩티드 및 이를 포함하는 조성물 |
| EP3138399B1 (en) | 2014-04-30 | 2023-09-06 | Gemvax & Kael Co., Ltd. | Composition for organ, tissue, or cell transplantation, kit, and transplantation method |
| KR102413243B1 (ko) | 2014-12-23 | 2022-06-27 | 주식회사 젬백스앤카엘 | 안질환 치료 펩티드 및 이를 포함하는 안질환 치료용 조성물 |
| JP6751097B2 (ja) | 2015-02-27 | 2020-09-02 | ジェムバックス アンド カエル カンパニー，リミティド | 聴力損傷予防用ペプチド及びそれを含む組成物 |
| CN107667112B (zh) | 2015-05-26 | 2021-12-07 | 珍白斯凯尔有限公司 | 新型肽和含有其的组合物 |
| EP3318265B1 (en) | 2015-07-02 | 2021-08-18 | Gemvax & Kael Co., Ltd. | Peptide having anti-viral effect and composition containing same |
| JP6920324B2 (ja) * | 2015-11-03 | 2021-08-18 | ジェムバックス アンド カエル カンパニー，リミティド | 神経細胞の損失予防及び再生の効能を有するペプチド及びこれを含む組成物 |
| KR101661912B1 (ko) * | 2016-01-29 | 2016-10-04 | (주)넥스젠바이오텍 | 녹색형광단백질-인간 상피세포재생인자 융합단백질을 유효성분으로 포함하는 주름 개선 및 항노화 화장료 조성물 |
| WO2017176087A1 (ko) | 2016-04-07 | 2017-10-12 | 주식회사 젬백스앤카엘 | 텔로머라제 활성 증가 및 텔로미어 연장 효능을 가지는 펩티드 및 이를 포함하는 조성물 |
| US11446398B2 (en) | 2016-04-11 | 2022-09-20 | Obsidian Therapeutics, Inc. | Regulated biocircuit systems |
| EP3806888B1 (en) | 2018-06-12 | 2024-01-31 | Obsidian Therapeutics, Inc. | Pde5 derived regulatory constructs and methods of use in immunotherapy |
| US20210386788A1 (en) | 2018-10-24 | 2021-12-16 | Obsidian Therapeutics, Inc. | Er tunable protein regulation |
| WO2021046451A1 (en) | 2019-09-06 | 2021-03-11 | Obsidian Therapeutics, Inc. | Compositions and methods for dhfr tunable protein regulation |
| US20230181681A1 (en) * | 2020-05-08 | 2023-06-15 | Industry Academic Cooperation Foundation, Hallym University | Peptide for suppressing coronavirus and use thereof |
Family Cites Families (24)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6610839B1 (en) * | 1997-08-14 | 2003-08-26 | Geron Corporation | Promoter for telomerase reverse transcriptase |
| JP3869092B2 (ja) * | 1996-10-01 | 2007-01-17 | ジェロン・コーポレーション | ヒトテロメラーゼ触媒性サブユニット |
| US7030211B1 (en) | 1998-07-08 | 2006-04-18 | Gemvax As | Antigenic peptides derived from telomerase |
| GB0112342D0 (en) * | 2001-05-21 | 2001-07-11 | Norsk Hydro As | Polypeptides |
| WO2003038047A2 (en) * | 2001-10-29 | 2003-05-08 | Baylor College Of Medicine | Human telomerase reverse transcriptase as a class-ii restricted tumor-associated antigen |
| US7294708B2 (en) * | 2002-05-31 | 2007-11-13 | Beijing Institute Of Biotechnology | Telomerase reverse transcriptase fragments and uses thereof |
| JP2009519033A (ja) | 2005-12-16 | 2009-05-14 | ディアト | 核酸を細胞に送達するための細胞貫通ペプチド結合体 |
| US20100168034A1 (en) | 2006-02-20 | 2010-07-01 | Ewha University-Industry Collaboration Foundation | Peptide having cell membrane penetrating activity |
| AU2008211854C1 (en) | 2007-01-29 | 2014-01-23 | Procell Therapeutics Inc. | Novel macromolecule transduction domains and methods for identification and uses thereof |
| EP1994942A1 (en) * | 2007-05-25 | 2008-11-26 | INSERM (Institut National de la Santé et de la Recherche Médicale) | Pharmaceutical compositions comprising telomerase, and uses thereof |
| ES2602453T3 (es) * | 2008-06-16 | 2017-02-21 | Mediolanum Farmaceutici S.P.A. | Inmunoterapia antitumoral |
| ES2334315B1 (es) | 2008-07-29 | 2011-02-28 | Universitat Pompeu Fabra | Peptidos con capacidad de penetracion celular y sus usos. |
| US20110318380A1 (en) * | 2008-10-01 | 2011-12-29 | Dako Denmark A/S | MHC Multimers in Cancer Vaccines and Immune Monitoring |
| KR101169030B1 (ko) | 2009-01-21 | 2012-07-26 | 애니젠 주식회사 | 신규한 세포막 투과 도메인 및 이를 포함하는 세포내 전달 시스템 |
| KR101783291B1 (ko) | 2009-05-20 | 2017-09-29 | 도레이 카부시키가이샤 | 세포막 투과성 펩티드 |
| CN108383894A (zh) * | 2010-02-16 | 2018-08-10 | 阿尔特公司 | 多肽及其应用 |
| KR101263212B1 (ko) | 2010-05-28 | 2013-05-10 | 성신여자대학교 산학협력단 | 신규한 세포막 투과성 펩타이드 및 그의 용도 |
| WO2011150493A1 (en) * | 2010-05-30 | 2011-12-08 | The Governing Council Of The University Of Toronto | Mitochondrial penetrating peptides as carriers for antimicrobials |
| KR101348284B1 (ko) * | 2010-09-09 | 2014-01-03 | 주식회사 나이벡 | 인간 유래 세포 투과성 펩타이드와 생리활성 펩타이드 결합체 및 그 용도 |
| CN116694597A (zh) | 2012-05-11 | 2023-09-05 | 珍白斯凯尔有限公司 | 具有抗炎活性的肽及其在制备抗炎组合物中的应用 |
| KR101799904B1 (ko) | 2012-07-11 | 2017-11-22 | 주식회사 젬백스앤카엘 | 세포 투과성 펩티드, 그를 포함한 컨쥬게이트 및 그를 포함한 조성물 |
| ES2758451T3 (es) | 2012-09-19 | 2020-05-05 | Gemvax & Kael Co Ltd | Péptido de penetración celular, conjugado que comprende el mismo y composición que comprende el conjugado |
| EP3736282B1 (en) | 2012-09-19 | 2023-06-21 | Gemvax & Kael Co., Ltd. | Cell penetrating peptide, conjugate comprising same, and composition comprising conjugate |
| KR101778244B1 (ko) | 2014-05-13 | 2017-09-26 | 한양대학교 산학협력단 | 세포 투과성 펩티드 및 이를 이용한 생물학적 활성 물질의 전달방법 |
-
2013
- 2013-09-17 US US14/429,641 patent/US9631184B2/en active Active
- 2013-09-17 ES ES13839102T patent/ES2743919T3/es active Active
- 2013-09-17 TW TW102133733A patent/TWI598441B/zh active
- 2013-09-17 KR KR1020157009510A patent/KR102201430B1/ko active Active
- 2013-09-17 EP EP13839102.4A patent/EP2899199B1/en active Active
- 2013-09-17 WO PCT/KR2013/008445 patent/WO2014046481A1/ko not_active Ceased
- 2013-09-17 CN CN201910049089.3A patent/CN110064056B/zh active Active
- 2013-09-17 JP JP2015532965A patent/JP6510410B2/ja active Active
- 2013-09-17 CN CN201910048425.2A patent/CN110028554B/zh active Active
- 2013-09-17 CN CN201380057722.4A patent/CN104768967B/zh active Active
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