JP2011521897A5 - - Google Patents

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Publication number
JP2011521897A5
JP2011521897A5 JP2011505127A JP2011505127A JP2011521897A5 JP 2011521897 A5 JP2011521897 A5 JP 2011521897A5 JP 2011505127 A JP2011505127 A JP 2011505127A JP 2011505127 A JP2011505127 A JP 2011505127A JP 2011521897 A5 JP2011521897 A5 JP 2011521897A5
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JP
Japan
Prior art keywords
peptide ligand
moiety
nanoparticle
fluorescent
ligand according
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JP2011505127A
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English (en)
Japanese (ja)
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JP2011521897A (ja
JP5497006B2 (ja
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Priority claimed from PCT/US2009/040480 external-priority patent/WO2009129220A2/en
Publication of JP2011521897A publication Critical patent/JP2011521897A/ja
Publication of JP2011521897A5 publication Critical patent/JP2011521897A5/ja
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JP2011505127A 2008-04-14 2009-04-14 膵管腺癌の検出および治療のためのプレクチン−1標的化剤 Active JP5497006B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US4481808P 2008-04-14 2008-04-14
US61/044,818 2008-04-14
PCT/US2009/040480 WO2009129220A2 (en) 2008-04-14 2009-04-14 Plectin-1 targeted agents for detection and treatment of pancreatic ductal adenocarcinoma

Related Child Applications (1)

Application Number Title Priority Date Filing Date
JP2014042379A Division JP6046070B2 (ja) 2008-04-14 2014-03-05 膵管腺癌の検出および治療のためのプレクチン−1標的化剤

Publications (3)

Publication Number Publication Date
JP2011521897A JP2011521897A (ja) 2011-07-28
JP2011521897A5 true JP2011521897A5 (enExample) 2012-07-05
JP5497006B2 JP5497006B2 (ja) 2014-05-21

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Family Applications (3)

Application Number Title Priority Date Filing Date
JP2011505127A Active JP5497006B2 (ja) 2008-04-14 2009-04-14 膵管腺癌の検出および治療のためのプレクチン−1標的化剤
JP2014042379A Active JP6046070B2 (ja) 2008-04-14 2014-03-05 膵管腺癌の検出および治療のためのプレクチン−1標的化剤
JP2016223323A Pending JP2017048239A (ja) 2008-04-14 2016-11-16 膵管腺癌の検出および治療のためのプレクチン−1標的化剤

Family Applications After (2)

Application Number Title Priority Date Filing Date
JP2014042379A Active JP6046070B2 (ja) 2008-04-14 2014-03-05 膵管腺癌の検出および治療のためのプレクチン−1標的化剤
JP2016223323A Pending JP2017048239A (ja) 2008-04-14 2016-11-16 膵管腺癌の検出および治療のためのプレクチン−1標的化剤

Country Status (6)

Country Link
US (4) US8829159B2 (enExample)
EP (2) EP2862871A1 (enExample)
JP (3) JP5497006B2 (enExample)
CA (1) CA2758415C (enExample)
HK (1) HK1209438A1 (enExample)
WO (1) WO2009129220A2 (enExample)

Families Citing this family (21)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2009129220A2 (en) * 2008-04-14 2009-10-22 The Gereral Hospital Corporation Plectin-1 targeted agents for detection and treatment of pancreatic ductal adenocarcinoma
JP2013510094A (ja) * 2009-11-05 2013-03-21 ユニバーシティ オブ バージニア パテント ファウンデーション がんのバイオマーカーとしてプレクチン−1を検出するための組成物および方法
DE102010039289A1 (de) * 2010-08-12 2012-02-16 Leica Microsystems (Schweiz) Ag Mikroskopsystem
US10174361B2 (en) * 2011-11-10 2019-01-08 Exosome Diagnostics, Inc. Cerebrospinal fluid assay
WO2013109944A1 (en) * 2012-01-18 2013-07-25 The Trustees Of The University Of Pennsylvania Methods for assessing risk for cancer using biomarkers
US10860526B2 (en) * 2012-12-01 2020-12-08 The Regents Of The University Of California System and method of managing large data files
US9606123B2 (en) 2013-03-29 2017-03-28 University Of Virginia Patent Foundation Compositions and methods for diagnosing and monitoring ovarian cancer progression and treatment
WO2015017506A2 (en) * 2013-07-30 2015-02-05 Blend Therapeutics, Inc. Nanoparticle diagnostic and methods for treating disease
US10182791B2 (en) * 2013-10-07 2019-01-22 The Regents Of The University Of California Integrated ultrasound, OCT, PA and/or florescence imaging endoscope for diagnosing cancers in gastrointestinal, respiratory, and urogenital tracts
EP3378937B1 (en) * 2015-11-19 2021-06-09 Niigata University Peptide having accumulation specific to pancreatic cancer, and use of said peptide
US10611796B2 (en) 2016-03-16 2020-04-07 Council Of Scientific & Industrial Research Method for regressing pancreatic tumor by a liposomal formulation along with DNA vaccines
JP7197078B2 (ja) * 2016-04-08 2022-12-27 ジィールバイオ,インコーポレーテッド プレクチン1結合性抗体およびその使用
WO2017182873A2 (en) 2016-04-19 2017-10-26 Ureka Sarl Peptide-oligourea foldamer compounds and methods of their use
JP2019534285A (ja) * 2016-10-26 2019-11-28 カオ グループ、インク. 放射エネルギーによる崩壊の標的とされる癌結合性放射線不透過性ペプチド
WO2018227112A1 (en) 2017-06-09 2018-12-13 The Trustees Of Columbia University In The City Of New York Short tat oligomers for drug delivery
CN112105380A (zh) * 2017-10-11 2020-12-18 埃缇健康公司D/B/A泽尔拜尔 网蛋白-1结合抗体和其用途
CA3081925A1 (en) * 2017-11-18 2019-05-23 Nzola DE MAGALHAES Product and process for employing gc7 (n1-guanyl-1,7-diaminoheptane) based antigen binding conjugates in cancer therapy
US11890352B2 (en) 2018-02-27 2024-02-06 University Of Virginia Patent Foundation Plectin-targeted liposomes/PARP inhibitor in the treatment of cancer
IL280880B2 (en) 2018-08-27 2025-04-01 Regeneron Pharma Using Raman Spectroscopy in Downstream Purification
US20220026432A1 (en) * 2018-12-14 2022-01-27 Konica Minolta, Inc. Method for forecasting arrival of drug inside diseased tissue
CN114814200B (zh) * 2022-05-09 2025-06-27 浙江大学 一种纳米颗粒-荧光标记融合蛋白复合体及其单链dna检测方法

Family Cites Families (41)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4522811A (en) 1982-07-08 1985-06-11 Syntex (U.S.A.) Inc. Serial injection of muramyldipeptides and liposomes enhances the anti-infective activity of muramyldipeptides
DE3307869A1 (de) 1983-03-05 1984-09-06 Dragoco Gerberding & Co Gmbh, 3450 Holzminden Methylsubstituierte 1-((3-methylthio)-1-oxo-butyl)-cyclohex-2-ene, verfahren zu deren herstellung und deren verwendung als riech- und aromastoffe
WO1985003508A1 (en) 1984-02-08 1985-08-15 Cetus Corporation Toxin conjugates
US5051448A (en) 1984-07-24 1991-09-24 The Mclean Hospital Corporation GABA esters and GABA analog esters
JP2594123B2 (ja) 1987-09-12 1997-03-26 株式会社林原生物化学研究所 減感作剤
US5827934A (en) 1988-03-08 1998-10-27 The University Of Wyoming Cytotoxic diphtheria toxin fragments
US5169862A (en) 1989-07-07 1992-12-08 Peptide Technologies Corporation Analogs of viscosin and their uses
US5208020A (en) 1989-10-25 1993-05-04 Immunogen Inc. Cytotoxic agents comprising maytansinoids and their therapeutic use
IL98744A0 (en) 1990-07-06 1992-07-15 Gen Hospital Corp Method of studying biological tissue using monocrystalline particles
US5192746A (en) 1990-07-09 1993-03-09 Tanabe Seiyaku Co., Ltd. Cyclic cell adhesion modulation compounds
US5858784A (en) 1991-12-17 1999-01-12 The Regents Of The University Of California Expression of cloned genes in the lung by aerosol- and liposome-based delivery
ES2149768T3 (es) 1992-03-25 2000-11-16 Immunogen Inc Conjugados de agentes enlazantes de celulas derivados de cc-1065.
PL310897A1 (en) 1993-03-29 1996-01-08 Univ Cincinnati Analogues of yy peptide and their application
US5559103A (en) 1993-07-21 1996-09-24 Cytel Corporation Bivalent sialyl X saccharides
US5539085A (en) 1993-08-20 1996-07-23 Onyx Pharmaceuticals, Inc. Bcl-2 and R-ras complex
US5696093A (en) 1994-10-28 1997-12-09 Crc For Biopharmaceutical Research Pty Limited Method of treating nasal congestion using neuropeptide Y Y2 agonist peptides
US5574010A (en) 1994-11-14 1996-11-12 The Regents Of The University Of California Treatment of pancreatic tumors with peptide YY and analogs thereof
US5576423A (en) 1994-12-02 1996-11-19 Schering Corporation Antibodies to the slam protein expressed on activated T cells
US5968479A (en) 1995-01-30 1999-10-19 Daiichi Pure Chemicals Co., Ltd. Diagnostic marker
US20030100051A1 (en) * 1998-05-12 2003-05-29 Ruben Steven M. 97 human secreted proteins
DE19717904A1 (de) 1997-04-23 1998-10-29 Diagnostikforschung Inst Säurelabile und enzymatisch spaltbare Farbstoffkonstrukte zur Diagnostik mit Nahinfrarotlicht und zur Therapie
US6046167A (en) 1998-03-25 2000-04-04 University Of Cincinnati Peptide YY analogs
US6592847B1 (en) 1998-05-14 2003-07-15 The General Hospital Corporation Intramolecularly-quenched near infrared flourescent probes
US20030103975A1 (en) * 1999-11-03 2003-06-05 Jones Jonathan C.R. Modulation of angiogenesis and endothelialization
US20030069180A1 (en) * 2000-06-09 2003-04-10 Corixa Corporation Compositions and methods for the therapy and diagnosis of colon cancer
US20020177207A1 (en) * 2001-03-14 2002-11-28 Myriad Genetics, Incorporated Tsg101-interacting proteins and use thereof
AUPR290801A0 (en) * 2001-02-06 2001-03-01 Peter Maccallum Cancer Institute, The Substrate binding domain
WO2002098364A2 (en) * 2001-06-06 2002-12-12 The General Hospital Corporation Magnetic-nanoparticle conjugates and methods of use
WO2003030725A2 (en) * 2001-10-11 2003-04-17 The Johns Hopkins University Pancreatic cancer diagnosis and therapies
US20050249668A1 (en) * 2002-03-29 2005-11-10 Ralph Weissleder Nir-fluorescent cyanine dyes, their synthesis and biological use
US20040018622A1 (en) * 2002-07-17 2004-01-29 Mitchell Lloyd G. Spliceosome mediated RNA trans-splicing for correction of skin disorders
AU2002951346A0 (en) * 2002-09-05 2002-09-26 Garvan Institute Of Medical Research Diagnosis of ovarian cancer
US20050260639A1 (en) 2002-09-30 2005-11-24 Oncotherapy Science, Inc. Method for diagnosing pancreatic cancer
EA008829B1 (ru) 2002-12-17 2007-08-31 Нэстек Фармасьютикал Кампани Инк. Композиции и способы для усовершенствованной доставки пептидов, связывающихся с y-рецепторами, которую осуществляют через слизистые оболочки, и способы лечения и предотвращения ожирения
WO2004099432A2 (en) 2003-05-02 2004-11-18 The Johns Hopkins University Identification of biomarkers for detecting pancreatic cancer
EP1756165A2 (en) * 2004-06-02 2007-02-28 Sidney Kimmel Cancer Center Tissue-specific imaging and therapeutical agents targeting proteins expressed on lung endothelial cell surface
ES2360519T3 (es) 2005-04-22 2011-06-06 University Of Washington Conjugado de cianina-clorotoxina y procedimiento para la visualización intraquirúrgica del cáncer.
EP2005187A4 (en) * 2006-03-23 2010-04-21 Life Technologies Corp METHOD AND REAGENTS FOR IN VIVO IMAGING CANCER CELL LINES
KR20100074177A (ko) 2007-09-10 2010-07-01 유니버시티 오브 매사추세츠 미토콘드리아-표적화된 항-종양 물질
WO2009129220A2 (en) * 2008-04-14 2009-10-22 The Gereral Hospital Corporation Plectin-1 targeted agents for detection and treatment of pancreatic ductal adenocarcinoma
CA2745307A1 (en) * 2008-12-12 2010-06-17 University Of Massachusetts Polyesters with grafted zwitterions

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